DE602006020052D1 - Neue arzneimittel gegen demenz - Google Patents

Neue arzneimittel gegen demenz

Info

Publication number
DE602006020052D1
DE602006020052D1 DE602006020052T DE602006020052T DE602006020052D1 DE 602006020052 D1 DE602006020052 D1 DE 602006020052D1 DE 602006020052 T DE602006020052 T DE 602006020052T DE 602006020052 T DE602006020052 T DE 602006020052T DE 602006020052 D1 DE602006020052 D1 DE 602006020052D1
Authority
DE
Germany
Prior art keywords
against damage
new medicines
medicines against
new
damage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006020052T
Other languages
English (en)
Inventor
Robert Ternansky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE602006020052D1 publication Critical patent/DE602006020052D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602006020052T 2005-09-28 2006-09-28 Neue arzneimittel gegen demenz Active DE602006020052D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72206605P 2005-09-28 2005-09-28
US77263106P 2006-02-10 2006-02-10
PCT/US2006/038387 WO2007038772A1 (en) 2005-09-28 2006-09-28 Novel drugs for dementia

Publications (1)

Publication Number Publication Date
DE602006020052D1 true DE602006020052D1 (de) 2011-03-24

Family

ID=37708469

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006020052T Active DE602006020052D1 (de) 2005-09-28 2006-09-28 Neue arzneimittel gegen demenz

Country Status (4)

Country Link
US (1) US20080227806A1 (de)
EP (1) EP1931656B1 (de)
DE (1) DE602006020052D1 (de)
WO (1) WO2007038772A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100216875A1 (en) * 2006-12-20 2010-08-26 Gregory Hook Methods of treating alzheimer's disease
US20110105603A1 (en) * 2010-08-06 2011-05-05 American Life Science Pharmaceuticals, Inc. Compositions and methods for treating beta-amyloid related diseases
WO2011017600A2 (en) 2009-08-07 2011-02-10 American Life Science Pharmaceuticals, Inc. (Alsp Inc.) Compositions and methods for treating beta-amyloid related diseases
CN102695546B (zh) 2009-09-11 2014-09-10 前体生物药物股份公司 作为谷氨酰胺酰环化酶抑制剂的杂环衍生物
PL3461819T3 (pl) 2017-09-29 2020-11-30 Probiodrug Ag Inhibitory cyklazy glutaminylowej

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55115878A (en) * 1979-02-27 1980-09-06 Taisho Pharmaceut Co Ltd Epoxysuccinic acid derivative
JPS55153778A (en) * 1979-05-17 1980-11-29 Taisho Pharmaceut Co Ltd Epoxysuccinylamino acid derivative
US4942165A (en) * 1986-02-11 1990-07-17 Advanced Biologics, Inc. Treatment for Alzheimer's disease
JP2808877B2 (ja) * 1990-09-29 1998-10-08 大正製薬株式会社 エポキシスクシナム酸誘導体およびその中間体
EP0580161A1 (de) * 1992-07-22 1994-01-26 THE McLEAN HOSPITAL CORPORATION Prophylaktische und therapeutische Behandlung der Alzheimer'schen Krankheit
US5556853A (en) * 1993-10-29 1996-09-17 Takeda Chemical Industries, Ltd. Epoxysuccinic acid derivatives
EP0763029A1 (de) * 1994-05-31 1997-03-19 Takeda Chemical Industries, Ltd. Epoxybernsteinsäurederivate, ihre herstellung und verwendung
CA2217051C (en) * 1995-03-31 2006-05-30 Nippon Chemiphar Co., Ltd. Epoxysuccinic acid derivatives
US6110967A (en) * 1997-04-18 2000-08-29 Taiho Pharmaceuticals Co., Ltd. Epoxysuccinamide derivative or salt thereof
DE69815137T2 (de) * 1997-09-04 2004-04-08 Nippon Chemiphar Co. Ltd. Epoxybernsteinsäureamid-derivate
US6313268B1 (en) * 1998-10-16 2001-11-06 Vivian Y. H. Hook Secretases related to Alzheimer's dementia
WO2004084830A2 (en) 2003-03-21 2004-10-07 Buck Institute Method for treating alzheimer’s dementia

Also Published As

Publication number Publication date
EP1931656B1 (de) 2011-02-09
US20080227806A1 (en) 2008-09-18
EP1931656A1 (de) 2008-06-18
WO2007038772A1 (en) 2007-04-05

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