NO20004485D0 - Sykloalkenderivater, deres fremstilling og anvendelse - Google Patents

Sykloalkenderivater, deres fremstilling og anvendelse

Info

Publication number
NO20004485D0
NO20004485D0 NO20004485A NO20004485A NO20004485D0 NO 20004485 D0 NO20004485 D0 NO 20004485D0 NO 20004485 A NO20004485 A NO 20004485A NO 20004485 A NO20004485 A NO 20004485A NO 20004485 D0 NO20004485 D0 NO 20004485D0
Authority
NO
Norway
Prior art keywords
substituents
hydrocarbon group
group optionally
aliphatic hydrocarbon
hydrogen atom
Prior art date
Application number
NO20004485A
Other languages
English (en)
Other versions
NO20004485L (no
NO326426B1 (no
Inventor
Yuzo Ichimori
Masayuki Ii
Katsumi Itoh
Tomoyuki Kitazaki
Junji Yamada
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO20004485D0 publication Critical patent/NO20004485D0/no
Publication of NO20004485L publication Critical patent/NO20004485L/no
Publication of NO326426B1 publication Critical patent/NO326426B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/14—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
NO20004485A 1998-03-09 2000-09-08 Sykloalkenderivater, deres fremstilling og anvendelse NO326426B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5649298 1998-03-09
JP28436298 1998-10-06
PCT/JP1999/001103 WO1999046242A1 (fr) 1998-03-09 1999-03-08 Derives de cycloalcene, leur procede de fabrication et d'utilisation

Publications (3)

Publication Number Publication Date
NO20004485D0 true NO20004485D0 (no) 2000-09-08
NO20004485L NO20004485L (no) 2000-09-08
NO326426B1 NO326426B1 (no) 2008-12-01

Family

ID=26397446

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004485A NO326426B1 (no) 1998-03-09 2000-09-08 Sykloalkenderivater, deres fremstilling og anvendelse

Country Status (20)

Country Link
US (1) US6495604B1 (no)
EP (2) EP1524263A1 (no)
JP (2) JP3665712B2 (no)
KR (4) KR100779889B1 (no)
CN (1) CN100432049C (no)
AT (1) ATE287393T1 (no)
AU (1) AU747521B2 (no)
BR (1) BR9908610A (no)
CA (1) CA2320467C (no)
DE (1) DE69923300T2 (no)
DK (1) DK1063228T5 (no)
ES (1) ES2232114T3 (no)
HK (1) HK1031723A1 (no)
HU (1) HU230061B1 (no)
ID (1) ID25649A (no)
NO (1) NO326426B1 (no)
NZ (1) NZ505874A (no)
PT (1) PT1063228E (no)
RU (1) RU2214398C2 (no)
WO (1) WO1999046242A1 (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1524263A1 (en) 1998-03-09 2005-04-20 Takeda Pharmaceutical Company Limited prodrugs containing cycloalkene derivatives
US20040220103A1 (en) 1999-04-19 2004-11-04 Immunex Corporation Soluble tumor necrosis factor receptor treatment of medical disorders
KR20070095416A (ko) * 1999-08-06 2007-09-28 다케다 야쿠힌 고교 가부시키가이샤 치환 방향환 화합물, 그의 제조법 및 용도
WO2001040498A1 (fr) * 1999-11-29 2001-06-07 Takeda Chemical Industries, Ltd. Procede de production de derives optiquement actifs du cyclohexene et de leurs intermediaires
JP4863553B2 (ja) * 2000-02-04 2012-01-25 武田薬品工業株式会社 安定な乳化組成物
DE60124504T2 (de) 2000-02-04 2007-09-20 Takeda Pharmaceutical Co. Ltd. Stabile emulsionszubereitungen
CA2685447C (en) 2000-08-10 2013-05-28 Takeda Pharmaceutical Company Limited Pharmaceutical composition
JP4922507B2 (ja) * 2000-08-10 2012-04-25 武田薬品工業株式会社 医薬組成物
EP1334966B1 (en) 2000-10-18 2011-05-04 Takeda Pharmaceutical Company Limited Process for preparation of optically active sulfonamides and intermediates for their synthesis
WO2002045750A1 (fr) * 2000-12-08 2002-06-13 Takeda Chemical Industries, Ltd. Medicaments combines
JP4278384B2 (ja) 2001-03-21 2009-06-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 ビタミンｂ２還元体を含む医薬
WO2003013513A1 (en) * 2001-08-03 2003-02-20 Takeda Chemical Industries, Ltd. Stable emulsion composition
US20060058288A1 (en) * 2002-04-08 2006-03-16 Masayuki Ii Severe sepsis preventive therapeutic agent
WO2005056535A1 (en) * 2003-12-03 2005-06-23 Boehringer Ingelheim Pharmaceuticals, Inc. 1,2,3-triazole amide derivatives as inhibitors of cytokine production
TWI462745B (zh) * 2005-04-28 2014-12-01 Takeda Pharmaceutical 安定的乳化組成物
US7935835B2 (en) * 2005-09-14 2011-05-03 Daiichi Sankyo Company, Limited Substituted cycloalkene derivative
JP4962982B2 (ja) 2006-03-30 2012-06-27 国立大学法人広島大学 スクリーニング方法
US20090062355A1 (en) * 2006-04-20 2009-03-05 Takeda Pharmaceutical Company Limited Pharmaceutical Product
US20090105314A1 (en) * 2006-05-15 2009-04-23 Takeda Pharmaceutical Company Limited Pharmaceutical Agent
WO2008004673A1 (fr) 2006-07-07 2008-01-10 Takeda Pharmaceutical Company Limited Dérives de cycloalkène, procédé de production des dérivés et utilisation de ceux-ci
JP2008260760A (ja) * 2007-03-12 2008-10-30 Daiichi Sankyo Co Ltd 置換シクロアルケン誘導体を含有する医薬組成物
CN104744321A (zh) 2010-01-27 2015-07-01 武田药品工业株式会社 用于抑制由抗癌剂诱导的外周神经障碍的化合物
WO2012039447A1 (ja) 2010-09-24 2012-03-29 第一三共株式会社 置換シクロアルケン誘導体の結晶
US20150174160A1 (en) * 2012-07-03 2015-06-25 Jay Pravda Methods for treating, diagnosing and/or monitoring progression of oxo associated states
EP2902014B1 (en) 2012-09-26 2019-03-06 Takeda Pharmaceutical Company Limited Process for producing solid particles
CA2985325C (en) 2015-05-08 2023-09-26 Takeda Pharmaceutical Company Limited Cyclic compounds for inhibition of toll-like receptor 4
BR112019004520A2 (pt) 2016-09-09 2019-05-28 Takeda Pharmaceuticals Co composto, medicamento, métodos para inibição de um receptor toll-like 4 e para prevenção ou tratamento de uma doença, e, uso do composto.
EP3585768A4 (en) * 2017-02-24 2020-12-23 Taiwanj Pharmaceuticals Co., Ltd. SULFONAMIDE OR AMIDE COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE PROPHYLAXIS AND / OR TREATMENT OF AUTOIMMUNE, INFLAMMATORY, OR INFECTIOUS DISEASES

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2177522T3 (es) 1990-11-06 2002-12-16 Nippon Shinyaku Co Ltd Preparacion liofilizada y su procedimiento de realizacion.
US5576016A (en) 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
WO1995022973A1 (en) 1994-02-25 1995-08-31 Takeda Chemicals Industries, Ltd. Injectable emulsions containing antifungal triazole derivatives
EP0776886A4 (en) * 1994-08-18 1999-05-12 Chugai Pharmaceutical Co Ltd AMINO ACID DERIVATIVE WITH NITROGEN MONOXIDE SYNTHETASE INHIBITING ACTIVITY
JPH08109165A (ja) * 1994-08-18 1996-04-30 Chugai Pharmaceut Co Ltd 一酸化窒素合成酵素阻害作用を有するアミノ酸誘導体
EP1524263A1 (en) 1998-03-09 2005-04-20 Takeda Pharmaceutical Company Limited prodrugs containing cycloalkene derivatives
DE60124504T2 (de) 2000-02-04 2007-09-20 Takeda Pharmaceutical Co. Ltd. Stabile emulsionszubereitungen

Also Published As

Publication number Publication date
KR20010034555A (ko) 2001-04-25
DE69923300T2 (de) 2006-01-05
CA2320467C (en) 2010-05-04
EP1063228A4 (en) 2001-08-08
PL342826A1 (en) 2001-07-02
ATE287393T1 (de) 2005-02-15
ES2232114T3 (es) 2005-05-16
HUP0101192A2 (hu) 2001-08-28
US6495604B1 (en) 2002-12-17
NO20004485L (no) 2000-09-08
KR100779889B1 (ko) 2007-11-28
EP1524263A1 (en) 2005-04-20
DE69923300D1 (de) 2005-02-24
PT1063228E (pt) 2005-05-31
DK1063228T5 (da) 2009-06-15
WO1999046242A1 (fr) 1999-09-16
CN100432049C (zh) 2008-11-12
AU2746499A (en) 1999-09-27
JP4342453B2 (ja) 2009-10-14
JP2005232168A (ja) 2005-09-02
KR20060017921A (ko) 2006-02-27
NZ505874A (en) 2003-09-26
CA2320467A1 (en) 1999-09-16
AU747521B2 (en) 2002-05-16
KR20050071719A (ko) 2005-07-07
KR100577044B1 (ko) 2006-05-08
ID25649A (id) 2000-10-19
JP2000178246A (ja) 2000-06-27
HK1031723A1 (en) 2001-06-22
EP1063228A1 (en) 2000-12-27
KR20050026075A (ko) 2005-03-14
JP3665712B2 (ja) 2005-06-29
BR9908610A (pt) 2000-12-05
HU230061B1 (hu) 2015-06-29
HUP0101192A3 (en) 2003-09-29
EP1063228B1 (en) 2005-01-19
DK1063228T3 (da) 2005-04-25
CN1291184A (zh) 2001-04-11
RU2214398C2 (ru) 2003-10-20
NO326426B1 (no) 2008-12-01
AU747521C (en) 1999-09-27
KR100492098B1 (ko) 2005-06-01

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Legal Events

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