DE69814800T2 - Epoxysuccinamid-derivate oder ihre salze - Google Patents

Epoxysuccinamid-derivate oder ihre salze

Info

Publication number
DE69814800T2
DE69814800T2 DE69814800T DE69814800T DE69814800T2 DE 69814800 T2 DE69814800 T2 DE 69814800T2 DE 69814800 T DE69814800 T DE 69814800T DE 69814800 T DE69814800 T DE 69814800T DE 69814800 T2 DE69814800 T2 DE 69814800T2
Authority
DE
Germany
Prior art keywords
substituted
group
alkyl
salt
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69814800T
Other languages
English (en)
Other versions
DE69814800D1 (de
Inventor
Tetsuji Asao
Tomohiro Yamashita
Yoshimitsu Suda
Shigeo Okajima
Yukio Tada
Nobuhiko Katsunuma
Shozo Yamada
Kazuhiko Shigeno
Atsuhiko Uemura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69814800D1 publication Critical patent/DE69814800D1/de
Publication of DE69814800T2 publication Critical patent/DE69814800T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epoxy Compounds (AREA)
DE69814800T 1997-04-18 1998-04-17 Epoxysuccinamid-derivate oder ihre salze Expired - Fee Related DE69814800T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10215197 1997-04-18
PCT/JP1998/001778 WO1998047887A1 (fr) 1997-04-18 1998-04-17 Nouveaux derives d'epoxysuccinamide et sels associes

Publications (2)

Publication Number Publication Date
DE69814800D1 DE69814800D1 (de) 2003-06-26
DE69814800T2 true DE69814800T2 (de) 2003-12-18

Family

ID=14319744

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69814800T Expired - Fee Related DE69814800T2 (de) 1997-04-18 1998-04-17 Epoxysuccinamid-derivate oder ihre salze

Country Status (8)

Country Link
US (1) US6110967A (de)
EP (1) EP0921122B1 (de)
JP (1) JP3410476B2 (de)
AT (1) ATE240949T1 (de)
AU (1) AU727497B2 (de)
CA (1) CA2258354A1 (de)
DE (1) DE69814800T2 (de)
WO (1) WO1998047887A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITPD980169A1 (it) * 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
US20040009891A1 (en) * 2001-02-14 2004-01-15 Newmillennium Pharmaceutical, Inc. Method and composition for treating obesity by targeting cathepsin
US6620844B2 (en) * 2001-02-14 2003-09-16 Newmillennium Pharmaceutical, Inc. Method for reducing blood insulin levels by reducing in vivo cathepsin L activity
EP1474425B9 (de) * 2002-01-07 2008-07-02 Eisai Co., Ltd. Desazapurine und deren verwendung
ITPD20050056A1 (it) * 2005-03-02 2006-09-03 Fidia Farmaceutici Derivati ammidici del'acido ialuronico in osteoartrosi
US20080227806A1 (en) * 2005-09-28 2008-09-18 American Life Science Pharmaceuticals Novel Drugs for Dementia
BRPI0712868A2 (pt) * 2006-06-13 2013-05-07 Univ Leland Stanford Junior inibidores epàxidos de cisteÍna proteases
US20100216875A1 (en) * 2006-12-20 2010-08-26 Gregory Hook Methods of treating alzheimer's disease
US20110092484A1 (en) 2007-06-08 2011-04-21 Nippon Chemiphar Co., Ltd. Therapeutic or prophylactic agent for cerebral aneurysm
JPWO2009054454A1 (ja) 2007-10-24 2011-03-03 国立大学法人 東京医科歯科大学 カテプシン阻害剤を有効成分として含有するＴｏｌｌ様受容体のシグナル伝達の調整剤
CN101967209B (zh) * 2010-10-20 2012-11-07 南京大学 一种n-乙酰基乙二胺螯合树脂及其制备方法
WO2013116663A1 (en) 2012-02-01 2013-08-08 The Trustees Of Columbia University In The City Of New York Novel cysteine protease inhibitors and uses thereof
CN104211666B (zh) * 2013-05-31 2017-11-14 中国人民解放军军事医学科学院毒物药物研究所 2,3‑环氧丁二酰胺类化合物、其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556853A (en) * 1993-10-29 1996-09-17 Takeda Chemical Industries, Ltd. Epoxysuccinic acid derivatives
JPH08104683A (ja) * 1993-10-29 1996-04-23 Takeda Chem Ind Ltd エポキシコハク酸誘導体
CA2190151A1 (en) * 1994-05-31 1995-12-07 Shigetoshi Tsubotani Epoxysuccinic acid derivatives, their production and use
JPH08104684A (ja) * 1994-05-31 1996-04-23 Takeda Chem Ind Ltd エポキシコハク酸関連化合物
AU697565B2 (en) * 1995-12-12 1998-10-08 Taiho Pharmaceutical Co., Ltd. Epoxysuccinamide derivative or salt thereof and medicine comprising the same

Also Published As

Publication number Publication date
WO1998047887A1 (fr) 1998-10-29
ATE240949T1 (de) 2003-06-15
JP3410476B2 (ja) 2003-05-26
AU727497B2 (en) 2000-12-14
US6110967A (en) 2000-08-29
EP0921122A1 (de) 1999-06-09
EP0921122A4 (de) 2001-06-13
DE69814800D1 (de) 2003-06-26
AU6853798A (en) 1998-11-13
CA2258354A1 (en) 1998-10-29
EP0921122B1 (de) 2003-05-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee