US6143298A
(en)
*
|
1988-09-01 |
2000-11-07 |
Bayer Corporation |
Soluble truncated forms of ICAM-1
|
ES2141076T3
(es)
|
1988-09-01 |
2000-03-16 |
Bayer Ag |
Proteina del receptor de rinovirus humano que inhibe la infectividad del virus.
|
US6514936B1
(en)
|
1988-09-01 |
2003-02-04 |
Bayer Corporation |
Antiviral methods using human rhinovirus receptor (ICAM-1)
|
US6051231A
(en)
*
|
1988-09-01 |
2000-04-18 |
Bayer Corporation |
Antiviral methods and prepations
|
NZ237688A
(en)
*
|
1990-04-19 |
1993-01-27 |
Res Dev Foundation |
Antibody-cytotoxic immunoconjugate-containing compositions and cancer treatment
|
US20030064480A1
(en)
*
|
1990-06-28 |
2003-04-03 |
Leander Lauffer |
Fusion proteins with immunoglobulin portions, the preparation and use thereof
|
US6130202A
(en)
*
|
1990-07-20 |
2000-10-10 |
Bayer Corporation |
Antiviral methods
|
US6107461A
(en)
*
|
1990-07-20 |
2000-08-22 |
Bayer Corporation |
Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
|
DE69131564T2
(de)
*
|
1990-07-20 |
2000-01-13 |
Bayer Ag |
Multimere Formen des menschlichen Rhinovirus-Rezeptorproteins
|
US6407221B1
(en)
*
|
1990-12-14 |
2002-06-18 |
Cell Genesys, Inc. |
Chimeric chains for receptor-associated signal transduction pathways
|
US6605712B1
(en)
*
|
1990-12-20 |
2003-08-12 |
Arch Development Corporation |
Gene transcription and ionizing radiation: methods and compositions
|
IL101147A
(en)
*
|
1991-03-07 |
2004-06-20 |
Gen Hospital Corp |
Change of direction of cellular immunity by chimera receptors
|
US5851828A
(en)
*
|
1991-03-07 |
1998-12-22 |
The General Hospital Corporation |
Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
|
US5843728A
(en)
*
|
1991-03-07 |
1998-12-01 |
The General Hospital Corporation |
Redirection of cellular immunity by receptor chimeras
|
US6753162B1
(en)
|
1991-03-07 |
2004-06-22 |
The General Hospital Corporation |
Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
|
US5912170A
(en)
*
|
1991-03-07 |
1999-06-15 |
The General Hospital Corporation |
Redirection of cellular immunity by protein-tyrosine kinase chimeras
|
US7049136B2
(en)
|
1991-03-07 |
2006-05-23 |
The General Hospital Corporation |
Redirection of cellular immunity by receptor chimeras
|
US6004811A
(en)
|
1991-03-07 |
1999-12-21 |
The Massachussetts General Hospital |
Redirection of cellular immunity by protein tyrosine kinase chimeras
|
WO1993010218A1
(en)
*
|
1991-11-14 |
1993-05-27 |
The United States Government As Represented By The Secretary Of The Department Of Health And Human Services |
Vectors including foreign genes and negative selective markers
|
IL104570A0
(en)
*
|
1992-03-18 |
1993-05-13 |
Yeda Res & Dev |
Chimeric genes and cells transformed therewith
|
US8211422B2
(en)
|
1992-03-18 |
2012-07-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric receptor genes and cells transformed therewith
|
JPH07509694A
(ja)
*
|
1992-05-14 |
1995-10-26 |
ベイラー・カレッジ・オブ・メディシン |
突然変異したステロイドホルモン受容体,その使用方法および遺伝子治療のための分子スイッチ
|
AU679120B2
(en)
*
|
1993-09-03 |
1997-06-19 |
Systemix, Inc. |
Genetically modified human hematopoietic stem cells and their progeny
|
AU2207195A
(en)
*
|
1994-04-05 |
1995-10-23 |
Board Of Regents, The University Of Texas System |
Modified receptors that continuously signal
|
PT758394E
(pt)
|
1994-05-02 |
2003-04-30 |
Bernd Groner |
Proteina bifuncional sua preparacao e utilizacao
|
US5985660A
(en)
*
|
1994-06-15 |
1999-11-16 |
Systemix, Inc. |
Method of identifying biological response modifiers involved in dendritic and/or lymphoid progenitor cell proliferation and/or differentiation
|
US5972627A
(en)
*
|
1994-06-15 |
1999-10-26 |
Systemix, Inc. |
Method of purifying a population of cells enriched for dendritic and/or lymphoid progenitors and populations of cells obtained thereby
|
CA2204183A1
(en)
*
|
1994-11-01 |
1996-05-09 |
Andrew Lawrence Feldhaus |
Chimeric receptors for the generation of selectively-activatable th-independent cytotoxic t cells
|
US7820798B2
(en)
*
|
1994-11-07 |
2010-10-26 |
Human Genome Sciences, Inc. |
Tumor necrosis factor-gamma
|
US7597886B2
(en)
*
|
1994-11-07 |
2009-10-06 |
Human Genome Sciences, Inc. |
Tumor necrosis factor-gamma
|
WO1996018105A1
(en)
*
|
1994-12-06 |
1996-06-13 |
The President And Fellows Of Harvard College |
Single chain t-cell receptor
|
US5837544A
(en)
*
|
1995-02-02 |
1998-11-17 |
Cell Genesys, Inc. |
Method of inducing a cell to proliferate using a chimeric receptor comprising janus kinase
|
US5712149A
(en)
*
|
1995-02-03 |
1998-01-27 |
Cell Genesys, Inc. |
Chimeric receptor molecules for delivery of co-stimulatory signals
|
US6103521A
(en)
*
|
1995-02-06 |
2000-08-15 |
Cell Genesys, Inc. |
Multispecific chimeric receptors
|
US5891680A
(en)
*
|
1995-02-08 |
1999-04-06 |
Whitehead Institute For Biomedical Research |
Bioactive fusion proteins comprising the p35 and p40 subunits of IL-12
|
NZ337002A
(en)
*
|
1995-02-24 |
2005-07-29 |
Gen Hospital Corp |
Redirection of cellular immunity by receptor chimeras
|
US5830755A
(en)
*
|
1995-03-27 |
1998-11-03 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
T-cell receptors and their use in therapeutic and diagnostic methods
|
KR19980703665A
(ko)
*
|
1995-04-04 |
1998-12-05 |
카렌 크루벤 |
세포 표면상 제 1 류 mhc 단백질의 수준이 낮은 유전적으로변형된 세포의 이식
|
US5866416A
(en)
*
|
1995-04-07 |
1999-02-02 |
The United States Of America As Represented By The Secretary Of Agriculture |
Cell line for propagating receptor binding site-deleted FMDV
|
US7429646B1
(en)
|
1995-06-05 |
2008-09-30 |
Human Genome Sciences, Inc. |
Antibodies to human tumor necrosis factor receptor-like 2
|
US6015554A
(en)
*
|
1995-06-07 |
2000-01-18 |
Systemix, Inc. |
Method of reconstituting human lymphoid and dendritic cells
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
US6685940B2
(en)
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
US6017754A
(en)
*
|
1995-08-24 |
2000-01-25 |
Invitrogen Corporation |
System for isolating and identifying eukaryotic cells transfected with genes and vectors, host cells and methods thereof
|
DE19540515C1
(de)
*
|
1995-10-31 |
1997-02-06 |
Boehringer Ingelheim Int |
Tumortherapie durch adoptiven Transfer CD44v-spezifischer zytotoxischer T-Lymphozyten
|
US6699715B1
(en)
|
1995-11-30 |
2004-03-02 |
Bristol-Myers Squibb Co. |
Modified sFv molecules which mediate adhesion between cells and uses thereof
|
WO1997020048A2
(en)
*
|
1995-11-30 |
1997-06-05 |
Bristol-Myers Squibb Company |
Modified sfv molecules which mediate adhesion between cells and uses thereof
|
EP0888381A4
(en)
*
|
1995-12-21 |
2001-10-17 |
Scripps Research Inst |
TARGETED THERAPEUTIC AND DIAGNOSTIC AGENTS, METHODS FOR THEIR PRODUCTION AND USE
|
GB9526131D0
(en)
*
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Recombinant chimeric receptors
|
US7888466B2
(en)
|
1996-01-11 |
2011-02-15 |
Human Genome Sciences, Inc. |
Human G-protein chemokine receptor HSATU68
|
US7084252B1
(en)
|
1996-01-16 |
2006-08-01 |
The Rockefeller University |
DB, the receptor for leptin
|
US7063958B1
(en)
|
1996-01-16 |
2006-06-20 |
The Rockefeller University |
Nucleic acids db, the receptor for leptin
|
US7148004B1
(en)
*
|
1997-01-16 |
2006-12-12 |
The Rockefeller University |
Oligonucleotides of the OB-R isoforms and methods of diagnosing body weight
|
WO1997026328A1
(en)
|
1996-01-17 |
1997-07-24 |
Imperial College Innovations Limited |
Immunotherapy using cytotoxic t lymphocytes (ctl)
|
US7619079B2
(en)
*
|
1996-02-14 |
2009-11-17 |
The Rockefeller University |
Db, the receptor for leptin, nucleic acids encoding the receptor, and uses thereof
|
WO1997033978A1
(en)
*
|
1996-03-12 |
1997-09-18 |
Life Technologies, Inc. |
Hematopoietic cell culture nutrient supplement
|
US6451995B1
(en)
|
1996-03-20 |
2002-09-17 |
Sloan-Kettering Institute For Cancer Research |
Single chain FV polynucleotide or peptide constructs of anti-ganglioside GD2 antibodies, cells expressing same and related methods
|
US6060054A
(en)
*
|
1996-04-10 |
2000-05-09 |
National Jewish Medical And Research Center |
Product for T lymphocyte immunosuppression
|
JP2001519650A
(ja)
*
|
1996-04-15 |
2001-10-23 |
ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ |
可溶性7回貫膜ドメインgタンパク質共役受容体、組成物及び方法
|
EP0937095A4
(en)
*
|
1996-10-25 |
1999-12-22 |
Cell Genesys Inc |
TARGETED CYTOLYSIS OF CANCER CELLS
|
US5969102A
(en)
|
1997-03-03 |
1999-10-19 |
St. Jude Children's Research Hospital |
Lymphocyte surface receptor that binds CAML, nucleic acids encoding the same and methods of use thereof
|
WO1999028349A2
(en)
|
1997-12-02 |
1999-06-10 |
Medarex, Inc. |
CELLS EXPRESSING ANTI-Fc RECEPTOR BINDING COMPONENTS
|
ZA9811162B
(en)
|
1997-12-12 |
2000-06-07 |
Genentech Inc |
Treatment with anti-ERBB2 antibodies.
|
CA2323776C
(en)
|
1998-03-19 |
2010-04-27 |
Human Genome Sciences, Inc. |
Cytokine receptor common gamma chain like
|
GB9809658D0
(en)
*
|
1998-05-06 |
1998-07-01 |
Celltech Therapeutics Ltd |
Biological products
|
US6410319B1
(en)
|
1998-10-20 |
2002-06-25 |
City Of Hope |
CD20-specific redirected T cells and their use in cellular immunotherapy of CD20+ malignancies
|
US6534633B1
(en)
*
|
1998-10-21 |
2003-03-18 |
Altor Bioscience Corporation |
Polyspecific binding molecules and uses thereof
|
US6855549B1
(en)
|
1998-11-23 |
2005-02-15 |
The University Of Iowa Research Foundation |
Methods and compositions for increasing the infectivity of gene transfer vectors
|
US6156515A
(en)
*
|
1999-02-09 |
2000-12-05 |
Urocor, Inc. |
Prostate-specific gene for diagnosis, prognosis and management of prostate cancer
|
EP2357192A1
(en)
|
1999-02-26 |
2011-08-17 |
Human Genome Sciences, Inc. |
Human endokine alpha and methods of use
|
US6200803B1
(en)
|
1999-05-21 |
2001-03-13 |
Rosetta Inpharmatics, Inc. |
Essential genes of yeast as targets for antifungal agents, herbicides, insecticides and anti-proliferative drugs
|
US6197517B1
(en)
|
1999-05-21 |
2001-03-06 |
Rosetta Inpharmatics, Inc. |
Essential genes of yeast as targets for antifungal agents, herbicides, insecticides and anti-proliferative drugs
|
US6221597B1
(en)
|
1999-05-21 |
2001-04-24 |
Rosetta Inpharmatics, Inc. |
Essential genes of yeast as targets for antifungal agents, herbicides, insecticides and anti-proliferative drugs
|
EP1754488A1
(en)
|
1999-05-24 |
2007-02-21 |
Introgen Therapeutics, Inc. |
Methods and compositions for non-viral gene therapy for treatment of hyperproliferative diseases
|
US20040013667A1
(en)
*
|
1999-06-25 |
2004-01-22 |
Genentech, Inc. |
Treatment with anti-ErbB2 antibodies
|
US6949245B1
(en)
*
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
CN100381172C
(zh)
*
|
1999-06-25 |
2008-04-16 |
吉尼泰克公司 |
使用抗-ErbB2抗体治疗前列腺癌
|
US20030086924A1
(en)
*
|
1999-06-25 |
2003-05-08 |
Genentech, Inc. |
Treatment with anti-ErbB2 antibodies
|
US7041292B1
(en)
|
1999-06-25 |
2006-05-09 |
Genentech, Inc. |
Treating prostate cancer with anti-ErbB2 antibodies
|
US6632628B1
(en)
|
1999-08-20 |
2003-10-14 |
Board Of Regents, The University Of Texas System |
Methods and compositions relating to HDAC 4 and 5 regulation of cardiac gene expression
|
US6627196B1
(en)
*
|
1999-08-27 |
2003-09-30 |
Genentech, Inc. |
Dosages for treatment with anti-ErbB2 antibodies
|
US7514259B2
(en)
*
|
2000-02-11 |
2009-04-07 |
Schepens Eye Research Institute |
Isolation and transplantation of retinal stem cells
|
WO2001083781A2
(en)
*
|
2000-04-28 |
2001-11-08 |
Millennium Pharmaceuticals, Inc. |
14094, a novel human trypsin family member and uses thereof
|
ATE441433T1
(de)
|
2000-05-19 |
2009-09-15 |
Genentech Inc |
Gennachweisverfahren zur verbesserung der wahrscheinlichkeit einer wirkungsvollen antwort auf eine krebstherapie mit einem erbb- antagonisten
|
IL136511A0
(en)
*
|
2000-06-01 |
2001-06-14 |
Gavish Galilee Bio Appl Ltd |
Genetically engineered mhc molecules
|
US20030031675A1
(en)
|
2000-06-06 |
2003-02-13 |
Mikesell Glen E. |
B7-related nucleic acids and polypeptides useful for immunomodulation
|
EP1294949A4
(en)
|
2000-06-15 |
2004-08-25 |
Human Genome Sciences Inc |
HUMAN TUMORNESCROSE FACTOR DELTA AND EPSILON
|
AU6842701A
(en)
|
2000-06-16 |
2002-01-14 |
Human Genome Sciences Inc |
Antibodies that immunospecifically bind to blys
|
AU2001297703B2
(en)
*
|
2000-11-07 |
2006-10-19 |
City Of Hope |
CD19-specific redirected immune cells
|
EP2027874B1
(en)
|
2000-11-28 |
2013-10-16 |
Medimmune, Inc. |
Methods of administering/dosing anti-rsv antibodies for prophylaxis and treatment
|
ES2649037T3
(es)
|
2000-12-12 |
2018-01-09 |
Medimmune, Llc |
Moléculas con semividas prolongadas, composiciones y usos de las mismas
|
EP1683865A3
(en)
|
2001-02-02 |
2006-10-25 |
Eli Lilly & Company |
Mammalian proteins and in particular CD200
|
US7175988B2
(en)
*
|
2001-02-09 |
2007-02-13 |
Human Genome Sciences, Inc. |
Human G-protein Chemokine Receptor (CCR5) HDGNR10
|
ZA200305980B
(en)
|
2001-02-12 |
2007-01-31 |
Res Dev Foundation |
Modified proteins, designer toxins, and methods of making thereof
|
AU2002250236A1
(en)
*
|
2001-03-02 |
2002-09-19 |
Medimmune, Inc. |
Cd2 antagonists for treatment of autoimmune or inflammatory disease
|
US8163289B2
(en)
|
2001-03-09 |
2012-04-24 |
Iterative Therapeutics, Inc. |
Methods and compositions involving polymeric immunoglobulin fusion proteins
|
WO2002072608A2
(en)
|
2001-03-09 |
2002-09-19 |
University Of Chicago |
POLYMERIC IMMUNOGLOBULIN FUSION PROTEINS THAT TARGET LOW-AFFINITY FCηRECEPTORS
|
US7723111B2
(en)
|
2001-03-09 |
2010-05-25 |
The United States Of America As Represented By The Department Of Health And Human Services |
Activated dual specificity lymphocytes and their methods of use
|
JP2004532213A
(ja)
*
|
2001-04-06 |
2004-10-21 |
ザ ユニヴァーシティ オヴ シカゴ |
Egr−1プロモーター活性の化学療法誘導
|
US20040242523A1
(en)
*
|
2003-03-06 |
2004-12-02 |
Ana-Farber Cancer Institue And The Univiersity Of Chicago |
Chemo-inducible cancer gene therapy
|
US8034791B2
(en)
|
2001-04-06 |
2011-10-11 |
The University Of Chicago |
Activation of Egr-1 promoter by DNA damaging chemotherapeutics
|
DE60236646D1
(de)
|
2001-04-13 |
2010-07-22 |
Human Genome Sciences Inc |
Anti-VEGF-2 Antikörper
|
US7514537B2
(en)
*
|
2001-04-30 |
2009-04-07 |
City Of Hope |
Chimeric immunoreceptor useful in treating human gliomas
|
AU2007237297B2
(en)
*
|
2001-04-30 |
2010-12-16 |
City Of Hope |
Chimeric immunoreceptor useful in treating human cancers
|
US11278594B2
(en)
|
2001-04-30 |
2022-03-22 |
City Of Hope |
Chimeric immunoreceptor useful in treating human cancers
|
US20030171546A1
(en)
*
|
2001-04-30 |
2003-09-11 |
City Of Hope |
Chimeric immunoreceptor useful in treating human cancers
|
US20090257994A1
(en)
|
2001-04-30 |
2009-10-15 |
City Of Hope |
Chimeric immunoreceptor useful in treating human cancers
|
JP4309758B2
(ja)
|
2001-05-25 |
2009-08-05 |
ヒューマン ジノーム サイエンシーズ, インコーポレイテッド |
Trailレセプターに免疫特異的に結合する抗体
|
IL159894A0
(en)
|
2001-07-17 |
2004-06-20 |
Res Dev Foundation |
Therapeutic agents comprising pro-apoptotic proteins
|
US6867189B2
(en)
*
|
2001-07-26 |
2005-03-15 |
Genset S.A. |
Use of adipsin/complement factor D in the treatment of metabolic related disorders
|
US20030148982A1
(en)
*
|
2001-11-13 |
2003-08-07 |
Brenner Malcolm K. |
Bi-spcific chimeric T cells
|
EP1534739A4
(en)
*
|
2002-01-18 |
2006-05-31 |
Bristol Myers Squibb Co |
IDENTIFICATION OF POLYNUCLEOTIDES AND POLYPEPTIDES FOR PREDICTING THE ACTIVITY OF COMPOUNDS THAT INTERACT WITH TYROSINE KINASE PROTEINS AND / OR TYROSINE KINASE PROTEIN PATHWAYS
|
WO2003070889A2
(en)
*
|
2002-02-19 |
2003-08-28 |
Idec Pharmaceuticals Corporation |
Prostate specific genes and the use thereof in design or therapeutics
|
WO2003085093A2
(en)
*
|
2002-04-01 |
2003-10-16 |
Human Genome Sciences, Inc. |
Antibodies that specifically bind to gmad
|
AU2003226065B2
(en)
|
2002-04-12 |
2009-02-26 |
Ludwig Institute For Cancer Research, Ltd |
Recombinant anti-interleukin-9 antibodies
|
US6790641B2
(en)
|
2002-05-01 |
2004-09-14 |
Cell Genesys, Inc. |
Lentiviral vector particles resistant to complement inactivation
|
JP4585968B2
(ja)
|
2002-05-10 |
2010-11-24 |
パーデュー・リサーチ・ファウンデーション |
EphA2アゴニストモノクローナル抗体およびその使用法
|
US7446190B2
(en)
*
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
AU2003275985A1
(en)
*
|
2002-06-12 |
2003-12-31 |
Research Development Foundation |
Immunotoxin as a therapeutic agent and uses thereof
|
US7425618B2
(en)
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
CA2495251C
(en)
|
2002-08-14 |
2018-03-06 |
Macrogenics, Inc. |
Fc.gamma.riib-specific antibodies and methods of use thereof
|
US20050272029A1
(en)
*
|
2002-08-16 |
2005-12-08 |
Bertrand Saunier |
Hepatitis c viral-like particle purification
|
WO2004035537A2
(en)
|
2002-10-16 |
2004-04-29 |
Euro-Celtique S.A. |
Antibodies that bind cell-associated ca 125/o772p and methods of use thereof
|
JP2006515748A
(ja)
*
|
2002-11-12 |
2006-06-08 |
ジェネンテック・インコーポレーテッド |
リウマチ様関節炎の治療のための組成物と方法
|
WO2004048525A2
(en)
*
|
2002-11-21 |
2004-06-10 |
Genentech, Inc. |
Therapy of non-malignant diseases or disorders with anti-erbb2 antibodies
|
US20050265992A1
(en)
*
|
2003-01-03 |
2005-12-01 |
The Research Foundation Of State University Of New York |
F11 receptor (F11R) antagonists as therapeutic agents
|
US8557957B2
(en)
|
2003-01-03 |
2013-10-15 |
Elizabeth Kornecki |
Methods of treating disorders by administration of F11 receptor antagonists
|
JP2006518997A
(ja)
*
|
2003-01-21 |
2006-08-24 |
ブリストル−マイヤーズ スクイブ カンパニー |
新規アシルコエンザイムa:モノアシルグリセロールアシルトランスフェラーゼ−3(mgat3)をコードするポリヌクレオチドおよびその用途
|
US7662387B2
(en)
|
2003-02-20 |
2010-02-16 |
Seattle Genetics |
Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
|
KR20120035234A
(ko)
|
2003-04-11 |
2012-04-13 |
메디뮨 엘엘씨 |
재조합 il?9 항체 및 그의 용도
|
US20050048617A1
(en)
|
2003-08-18 |
2005-03-03 |
Medimmune, Inc. |
Humanization of antibodies
|
US20130266551A1
(en)
|
2003-11-05 |
2013-10-10 |
St. Jude Children's Research Hospital, Inc. |
Chimeric receptors with 4-1bb stimulatory signaling domain
|
US20050113564A1
(en)
*
|
2003-11-05 |
2005-05-26 |
St. Jude Children's Research Hospital |
Chimeric receptors with 4-1BB stimulatory signaling domain
|
US7435596B2
(en)
*
|
2004-11-04 |
2008-10-14 |
St. Jude Children's Research Hospital, Inc. |
Modified cell line and method for expansion of NK cell
|
WO2005058961A2
(en)
*
|
2003-12-12 |
2005-06-30 |
Amgen Inc. |
Antibodies specific for human galanin, and uses thereof
|
EP1786463A4
(en)
*
|
2004-03-26 |
2009-05-20 |
Human Genome Sciences Inc |
ANTIBODY AGAINST NOGO RECEPTOR
|
US20050238628A1
(en)
*
|
2004-04-08 |
2005-10-27 |
Blau Carl A |
Methods for treating cancer
|
DE602005024148D1
(de)
*
|
2004-08-25 |
2010-11-25 |
Univ Chicago |
Verwendung der kombination aus temozolomid und tnf-alpha zur behandlung von glioblastoma
|
WO2006034292A2
(en)
|
2004-09-21 |
2006-03-30 |
Medimmune, Inc. |
Antibodies against and methods for producing vaccines for respiratory syncytial virus
|
WO2006036445A2
(en)
|
2004-09-24 |
2006-04-06 |
Trustees Of Dartmouth College |
Chimeric nk receptor and methods for treating cancer
|
EP2422811A2
(en)
|
2004-10-27 |
2012-02-29 |
MedImmune, LLC |
Modulation of antibody specificity by tailoring the affinity to cognate antigens
|
US20080112933A1
(en)
*
|
2004-11-08 |
2008-05-15 |
Scadden David T |
Methods and Compositions for Increasing Stem Cell Homing Using Gas Activators
|
AU2006210769A1
(en)
*
|
2005-02-01 |
2006-08-10 |
Research Development Foundation |
BLyS fusion proteins for targeting BLyS receptor and methods for treatment of B-cell proliferative disorders
|
EP1869192B1
(en)
|
2005-03-18 |
2016-01-20 |
MedImmune, LLC |
Framework-shuffling of antibodies
|
CN101198624B
(zh)
|
2005-05-06 |
2012-10-10 |
津莫吉尼蒂克斯公司 |
Il-31单克隆抗体及使用方法
|
ES2431315T3
(es)
|
2005-05-19 |
2013-11-26 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Epítopos funcionales del antígeno PsaA de Streptococcus pneumoniae y usos de los mismos
|
EP1893647A2
(en)
|
2005-06-23 |
2008-03-05 |
MedImmune, Inc. |
Antibody formulations having optimized aggregation and fragmentation profiles
|
WO2007008604A2
(en)
*
|
2005-07-08 |
2007-01-18 |
Bristol-Myers Squibb Company |
Single nucleotide polymorphisms associated with dose-dependent edema and methods of use thereof
|
WO2007021807A1
(en)
*
|
2005-08-12 |
2007-02-22 |
Schering Corporation |
Mcp1 fusions
|
US20070202512A1
(en)
*
|
2005-08-19 |
2007-08-30 |
Bristol-Myers Squibb Company |
Human single nucleotide polymorphisms associated with dose-dependent weight gain and methods of use thereof
|
EP1945261A4
(en)
|
2005-11-07 |
2010-05-12 |
Scripps Research Inst |
COMPOSITIONS AND METHODS FOR CONTROLLING THE SPECIFICITY OF TISSUE FACTOR SIGNALING
|
US8592149B2
(en)
|
2006-04-27 |
2013-11-26 |
Pikamab, Inc. |
Methods and compositions for antibody therapy
|
US20090304657A1
(en)
*
|
2006-05-03 |
2009-12-10 |
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services |
Chimeric t cell receptors and related materials and methods of use
|
HUE030269T2
(en)
|
2006-06-26 |
2017-04-28 |
Macrogenics Inc |
FC RIIB-specific antibodies and methods for their use
|
US7572618B2
(en)
|
2006-06-30 |
2009-08-11 |
Bristol-Myers Squibb Company |
Polynucleotides encoding novel PCSK9 variants
|
EA021255B1
(ru)
|
2006-08-28 |
2015-05-29 |
Киова Хакко Кирин Ко., Лимитед |
Антагонистические моноклональные антитела человека, специфичные в отношении light человека
|
EP2759549B1
(en)
|
2006-09-01 |
2015-08-19 |
ZymoGenetics, Inc. |
IL-31 monoclonal antibodies and methods of use
|
EP2082043A4
(en)
|
2006-10-10 |
2010-03-24 |
Viromed Co Ltd |
ENHANCED SAFETY EXPRESSION VECTORS
|
WO2008048545A2
(en)
|
2006-10-16 |
2008-04-24 |
Medimmune, Llc. |
Molecules with reduced half-lives, compositions and uses thereof
|
US20080254512A1
(en)
|
2006-11-02 |
2008-10-16 |
Capon Daniel J |
Hybrid immunoglobulins with moving parts
|
ES2523915T5
(es)
|
2006-12-01 |
2022-05-26 |
Seagen Inc |
Agentes de unión a la diana variantes y usos de los mismos
|
US9249423B2
(en)
|
2007-02-02 |
2016-02-02 |
Yale University |
Method of de-differentiating and re-differentiating somatic cells using RNA
|
US10155038B2
(en)
|
2007-02-02 |
2018-12-18 |
Yale University |
Cells prepared by transient transfection and methods of use thereof
|
US8859229B2
(en)
*
|
2007-02-02 |
2014-10-14 |
Yale University |
Transient transfection with RNA
|
RU2491094C2
(ru)
|
2007-03-30 |
2013-08-27 |
Медиммун, Ллк |
Препарат антитела
|
CA2685213C
(en)
|
2007-05-04 |
2017-02-21 |
Technophage, Investigacao E Desenvolvimento Em Biotecnologia, Sa |
Engineered rabbit antibody variable domains and uses thereof
|
JP2010527356A
(ja)
|
2007-05-14 |
2010-08-12 |
メディミューン,エルエルシー |
好酸球レベルを低下させる方法
|
US20080283557A1
(en)
*
|
2007-05-17 |
2008-11-20 |
Julianne Desautels |
Spout for food stuff container
|
CN101861391A
(zh)
|
2007-08-10 |
2010-10-13 |
韦恩州立大学 |
通过翻译调控基因表达系统检测和调节细胞死亡的组合物和方法
|
JO3076B1
(ar)
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
HUE036548T2
(hu)
|
2007-12-07 |
2018-08-28 |
Zymogenetics Inc |
IL-31-re specifikus humanizált antitest molekulák
|
US20090181409A1
(en)
*
|
2008-01-10 |
2009-07-16 |
Ye Fang |
Optical biosensor method for cell-cell interaction
|
ES2613963T3
(es)
|
2008-01-18 |
2017-05-29 |
Medimmune, Llc |
Anticuerpos manipulados con cisteína para conjugación específica de sitio
|
CA2723197C
(en)
|
2008-05-02 |
2017-09-19 |
Seattle Genetics, Inc. |
Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation
|
EP2815766B1
(en)
|
2008-08-05 |
2017-07-05 |
Novartis AG |
Compositions and methods for antibodies targeting complement protein C5
|
US20120128684A1
(en)
|
2008-08-25 |
2012-05-24 |
Burnham Institute For Medical Research |
Conserved Hemagglutinin Epitope, Antibodies to the Epitope and Methods of Use
|
EP2331566B1
(en)
|
2008-08-26 |
2015-10-07 |
City of Hope |
Method and compositions for enhanced anti-tumor effector functioning of t cells
|
US8852608B2
(en)
|
2009-02-02 |
2014-10-07 |
Medimmune, Llc |
Antibodies against and methods for producing vaccines for respiratory syncytial virus
|
WO2010093993A2
(en)
|
2009-02-12 |
2010-08-19 |
Human Genome Sciences, Inc. |
Use of b lymphocyte stimulator protein antagonists to promote transplantation tolerance
|
ES2548030T3
(es)
|
2009-06-01 |
2015-10-13 |
Medimmune, Llc |
Moléculas con semividas prolongadas y usos de las mismas
|
AU2010270979B2
(en)
|
2009-06-22 |
2015-04-23 |
Medimmune, Llc |
Engineered Fc regions for site-specific conjugation
|
HUE033312T2
(en)
|
2009-07-20 |
2017-11-28 |
Bristol Myers Squibb Co |
Combination of anti CTLA4 antibody with etoposide for synergistic treatment of proliferative diseases
|
EP2464657B1
(en)
|
2009-08-10 |
2015-04-01 |
MorphoSys AG |
Novel screening strategies for the identification of antibodies or fragments thereof which bind an antigen that has an enzymatic activity
|
WO2011020079A1
(en)
*
|
2009-08-13 |
2011-02-17 |
Calmune Corporation |
Antibodies against human respiratory syncytial virus (rsv) and methods of use
|
EP3381937A3
(en)
|
2009-08-13 |
2018-10-31 |
The Johns Hopkins University |
Methods of modulating immune function
|
US20110189183A1
(en)
|
2009-09-18 |
2011-08-04 |
Robert Anthony Williamson |
Antibodies against candida, collections thereof and methods of use
|
US9273283B2
(en)
|
2009-10-29 |
2016-03-01 |
The Trustees Of Dartmouth College |
Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
|
EP3187585A1
(en)
|
2010-03-25 |
2017-07-05 |
Oregon Health&Science University |
Cmv glycoproteins and recombinant vectors
|
ES2949159T3
(es)
|
2010-05-06 |
2023-09-26 |
Novartis Ag |
Composiciones y métodos de uso para anticuerpos terapéuticos de proteína 6 relacionada con lipoproteínas de baja densidad (LRP6)
|
KR20130066631A
(ko)
|
2010-05-06 |
2013-06-20 |
노파르티스 아게 |
치료적 저밀도 지단백질-관련 단백질 6 (lrp6) 다가 항체에 대한 조성물 및 사용 방법
|
US8524217B2
(en)
|
2010-05-11 |
2013-09-03 |
Merck Sharp & Dohme Corp. |
MCP1-Ig fusion variants
|
CA3062786C
(en)
|
2010-07-09 |
2022-04-19 |
Janssen Vaccines & Prevention B.V. |
Anti-human respiratory syncytial virus (rsv) antibodies and methods of use
|
MX356527B
(es)
|
2010-07-09 |
2018-06-01 |
Bioverativ Therapeutics Inc |
Polipeptidos de factor ix y metodos para usarlos.
|
WO2012019061A2
(en)
|
2010-08-05 |
2012-02-09 |
Stem Centrx, Inc. |
Novel effectors and methods of use
|
PT2606070T
(pt)
|
2010-08-20 |
2017-03-31 |
Novartis Ag |
Anticorpos para o recetor 3 do fator de crescimento epidérmico (her3)
|
EP2608807A1
(en)
|
2010-08-27 |
2013-07-03 |
Stem Centrx, Inc. |
Notum protein modulators and methods of use
|
SG10201506959SA
(en)
|
2010-09-03 |
2015-10-29 |
Stemcentrx Inc |
Novel modulators and methods of use
|
CN103153332A
(zh)
|
2010-09-28 |
2013-06-12 |
卡尔医疗有限公司 |
用于治疗血液恶性肿瘤的组合物和方法
|
CN103429620B
(zh)
|
2010-11-05 |
2018-03-06 |
酵活有限公司 |
在Fc结构域中具有突变的稳定异源二聚的抗体设计
|
EP2643353A1
(en)
|
2010-11-24 |
2013-10-02 |
Novartis AG |
Multispecific molecules
|
AU2011360938B2
(en)
|
2010-12-08 |
2016-07-28 |
Abbvie Stemcentrx Llc |
Novel modulators and methods of use
|
KR20230133410A
(ko)
|
2010-12-09 |
2023-09-19 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
암을 치료하기 위한 키메릭 항원 수용체 변형 t 세포의 용도
|
EP2668210B1
(en)
|
2011-01-26 |
2020-06-17 |
Celldex Therapeutics, Inc. |
Anti-kit antibodies and uses thereof
|
SA112330278B1
(ar)
|
2011-02-18 |
2015-10-09 |
ستيم سينتركس، انك. |
مواد ضابطة جديدة وطرق للاستخدام
|
US9244074B2
(en)
|
2011-06-07 |
2016-01-26 |
University Of Hawaii |
Biomarker of asbestos exposure and mesothelioma
|
WO2012170742A2
(en)
|
2011-06-07 |
2012-12-13 |
University Of Hawaii |
Treatment and prevention of cancer with hmgb1 antagonists
|
DK2691530T3
(da)
|
2011-06-10 |
2018-05-22 |
Univ Oregon Health & Science |
Cmv-glycoproteiner og rekombinante vektorer
|
WO2012172495A1
(en)
|
2011-06-14 |
2012-12-20 |
Novartis Ag |
Compositions and methods for antibodies targeting tem8
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
EP2568289A3
(en)
|
2011-09-12 |
2013-04-03 |
International AIDS Vaccine Initiative |
Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
|
SG11201400881SA
(en)
|
2011-09-23 |
2014-04-28 |
Technophage Investigação E Desenvolvimento Em Biotecnologia Sa |
Modified albumin-binding domains and uses thereof to improve pharmacokinetics
|
EP2586461A1
(en)
|
2011-10-27 |
2013-05-01 |
Christopher L. Parks |
Viral particles derived from an enveloped virus
|
AU2012332590B2
(en)
|
2011-11-01 |
2016-10-20 |
Bionomics, Inc. |
Anti-GPR49 antibodies
|
CN104053671A
(zh)
|
2011-11-01 |
2014-09-17 |
生态学有限公司 |
治疗癌症的抗体和方法
|
AU2012332593B2
(en)
|
2011-11-01 |
2016-11-17 |
Bionomics, Inc. |
Anti-GPR49 antibodies
|
ES2697674T3
(es)
|
2011-11-01 |
2019-01-25 |
Bionomics Inc |
Procedimientos para bloquear el crecimiento de células madre cancerosas
|
PT2773671T
(pt)
|
2011-11-04 |
2021-12-14 |
Zymeworks Inc |
Geração de anticorpo heterodimérico estável com mutações no domínio fc
|
RU2014122602A
(ru)
|
2011-11-04 |
2015-12-10 |
Новартис Аг |
Конструкции на основе белка, родственного липопротеинам низкой плотности, 6(lrp6), и удлинителя полупериода существования
|
EP2785740A1
(en)
|
2011-12-02 |
2014-10-08 |
Eli Lilly and Company |
Anti-glucagon antibodies and uses thereof
|
KR102083957B1
(ko)
|
2011-12-05 |
2020-03-04 |
노파르티스 아게 |
표피 성장 인자 수용체 3 (her3)에 대한 항체
|
KR20140103135A
(ko)
|
2011-12-05 |
2014-08-25 |
노파르티스 아게 |
Her3의 도메인 ii에 대해 지시된 표피 성장 인자 수용체 3 (her3)에 대한 항체
|
AU2012356170B2
(en)
|
2011-12-21 |
2016-06-16 |
Novartis Ag |
Compositions and methods for antibodies targeting Factor P
|
EP3539982A3
(en)
|
2011-12-23 |
2020-01-15 |
Pfizer Inc |
Engineered antibody constant regions for site-specific conjugation and methods and uses therefor
|
KR20140144680A
(ko)
|
2012-02-17 |
2014-12-19 |
더 셰펜스 아이 리써치 인스티튜트 |
인간의 망막 전구세포의 표현형 프로필
|
RU2014138474A
(ru)
|
2012-02-24 |
2016-04-10 |
СтемСентРкс, Инк. |
Новые модуляторы и способы применения
|
PE20150091A1
(es)
|
2012-02-24 |
2015-02-16 |
Stem Centrx Inc |
Anticuerpos anti-sez6 y metodos de empleo
|
AU2013258834B2
(en)
|
2012-05-10 |
2017-09-07 |
Zymeworks Bc Inc. |
Heteromultimer constructs of immunoglobulin heavy chains with mutations in the Fc domain
|
KR102247979B1
(ko)
|
2012-05-25 |
2021-05-04 |
셀렉티스 |
면역요법을 위한 동종이형 및 면역억제제 저항성인 t 세포의 조작 방법
|
EP2679596B1
(en)
|
2012-06-27 |
2017-04-12 |
International Aids Vaccine Initiative |
HIV-1 env glycoprotein variant
|
AU2013295848B2
(en)
|
2012-07-25 |
2018-05-24 |
Celldex Therapeutics, Inc. |
Anti-KIT antibodies and uses thereof
|
WO2014055657A1
(en)
*
|
2012-10-05 |
2014-04-10 |
The Trustees Of The University Of Pennsylvania |
Use of a trans-signaling approach in chimeric antigen receptors
|
US20150231240A1
(en)
|
2012-10-09 |
2015-08-20 |
Igenica Biotherapeutics, Inc. |
Anti-c16orf54 antibodies and methods of use thereof
|
WO2014084859A1
(en)
|
2012-11-30 |
2014-06-05 |
Novartis Ag |
Molecules and methods for modulating tmem16a activities
|
PT2928921T
(pt)
|
2012-12-05 |
2021-04-06 |
Novartis Ag |
Composições e métodos para anticorpos que visam epo
|
EP2935589A1
(en)
|
2012-12-18 |
2015-10-28 |
Novartis AG |
Compositions and methods that utilize a peptide tag that binds to hyaluronan
|
US20150329640A1
(en)
*
|
2012-12-20 |
2015-11-19 |
Bluebird Bio, Inc. |
Chimeric antigen receptors and immune cells targeting b cell malignancies
|
PL2956175T3
(pl)
|
2013-02-15 |
2018-05-30 |
The Regents Of The University Of California |
Chimeryczny receptor antygenowy i sposoby jego zastosowania
|
EP3626741A1
(en)
|
2013-02-20 |
2020-03-25 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
|
EP3744736A1
(en)
|
2013-02-20 |
2020-12-02 |
Novartis AG |
Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells
|
US9968687B2
(en)
|
2013-02-22 |
2018-05-15 |
Abbvie Stemcentrx Llc |
Anti-DLL3 antibody drug conjugates
|
EP3305812B1
(en)
|
2013-03-14 |
2020-06-17 |
Bristol-Myers Squibb Company |
Combination of dr5 agonist and anti-pd-1 antagonist and methods of use
|
WO2014159239A2
(en)
|
2013-03-14 |
2014-10-02 |
Novartis Ag |
Antibodies against notch 3
|
JP6602746B2
(ja)
|
2013-03-15 |
2019-11-06 |
カポン、ダニエル・ジェイ. |
非ペプチジル結合を含むハイブリッド免疫グロブリン
|
EP2968498A4
(en)
|
2013-03-15 |
2016-09-07 |
Biogen Ma Inc |
PREPARATIONS CONTAINING FACTOR IX POLYPEPTIDE
|
EP2970426B1
(en)
|
2013-03-15 |
2019-08-28 |
Michael C. Milone |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
TWI654206B
(zh)
|
2013-03-16 |
2019-03-21 |
諾華公司 |
使用人類化抗-cd19嵌合抗原受體治療癌症
|
US11077144B2
(en)
|
2013-05-13 |
2021-08-03 |
Cellectis |
CD19 specific chimeric antigen receptor and uses thereof
|
AU2014274660B2
(en)
|
2013-06-06 |
2019-05-16 |
Pierre Fabre Médicament |
Anti-C10orf54 antibodies and uses thereof
|
UY35620A
(es)
|
2013-06-21 |
2015-01-30 |
Novartis Ag |
Anticuerpos del receptor 1 de ldl oxidado similar a lectina y métodos de uso
|
AR096601A1
(es)
|
2013-06-21 |
2016-01-20 |
Novartis Ag |
Anticuerpos del receptor 1 de ldl oxidado similar a lectina y métodos de uso
|
RS62189B1
(sr)
|
2013-08-26 |
2021-08-31 |
Biontech Research And Development Inc |
Nukleinske kiseline koje kodiraju humana antitela na sijalil-luis a
|
US9993566B2
(en)
|
2013-08-28 |
2018-06-12 |
Abbvie Stemcentrx Llc |
SEZ6 modulators and methods of use
|
KR20160044042A
(ko)
|
2013-08-28 |
2016-04-22 |
스템센트알엑스 인코포레이티드 |
부위-특이적 항체 접합 방법 및 조성물
|
EP2848937A1
(en)
|
2013-09-05 |
2015-03-18 |
International Aids Vaccine Initiative |
Methods of identifying novel HIV-1 immunogens
|
EP2873423B1
(en)
|
2013-10-07 |
2017-05-31 |
International Aids Vaccine Initiative |
Soluble hiv-1 envelope glycoprotein trimers
|
AU2014342610A1
(en)
|
2013-11-04 |
2016-06-02 |
Abbvie Stemcentrx Llc |
Anti-EFNA4 antibody-drug conjugates
|
CA3225453A1
(en)
|
2013-12-19 |
2015-06-25 |
Novartis Ag |
Human mesothelin chimeric antigen receptors and uses thereof
|
US10287354B2
(en)
|
2013-12-20 |
2019-05-14 |
Novartis Ag |
Regulatable chimeric antigen receptor
|
CA2935951A1
(en)
|
2014-01-08 |
2015-07-16 |
1Globe Biomedical Co., Ltd. |
Novel synthetic biology-based adcc technology
|
EP3097117B1
(en)
|
2014-01-21 |
2023-10-04 |
Novartis Ag |
Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules
|
RU2701434C2
(ru)
|
2014-01-24 |
2019-09-26 |
Нгм Биофармасьютикалс, Инк. |
Связывающие белки и способы их применения
|
KR20170008202A
(ko)
|
2014-02-21 |
2017-01-23 |
애브비 스템센트알엑스 엘엘씨 |
흑색종에 사용하기 위한 항-dll3 항체 및 약물 접합체
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
DK3116486T3
(da)
|
2014-03-14 |
2020-03-09 |
Biomolecular Holdings Llc |
Hybrid immunoglobulin indeholdende ikke-peptidylbinding
|
US9738702B2
(en)
|
2014-03-14 |
2017-08-22 |
Janssen Biotech, Inc. |
Antibodies with improved half-life in ferrets
|
KR102352573B1
(ko)
|
2014-04-04 |
2022-01-18 |
바이오노믹스 인코포레이티드 |
Lgr5에 결합하는 인간화된 항체들
|
HUE054588T2
(hu)
|
2014-04-07 |
2021-09-28 |
Novartis Ag |
Rák kezelése CD19 elleni, kiméra antigénreceptor alkalmazásával
|
US10329556B2
(en)
|
2014-05-13 |
2019-06-25 |
Bioatla, Llc |
Conditionally active biological proteins
|
CN106459914B
(zh)
|
2014-05-15 |
2020-11-06 |
新加坡国立大学 |
经修饰的自然杀伤细胞及其用途
|
EP3888690A3
(en)
|
2014-05-16 |
2021-10-20 |
MedImmune, LLC |
Molecules with altered neonate fc receptor binding having enhanced therapeutic and diagnostic properties
|
CA2950602C
(en)
|
2014-06-04 |
2021-07-20 |
MabVax Therapeutics, Inc. |
Human monoclonal antibodies to ganglioside gd2
|
EP3161001A2
(en)
|
2014-06-25 |
2017-05-03 |
Novartis AG |
Antibodies specific for il-17a fused to hyaluronan binding peptide tags
|
WO2015198240A2
(en)
|
2014-06-25 |
2015-12-30 |
Novartis Ag |
Compositions and methods for long acting proteins
|
WO2015198243A2
(en)
|
2014-06-25 |
2015-12-30 |
Novartis Ag |
Compositions and methods for long acting proteins
|
AU2015292811B2
(en)
|
2014-07-21 |
2019-12-19 |
Novartis Ag |
Treatment of cancer using a CLL-1 chimeric antigen receptor
|
CN112481283A
(zh)
|
2014-07-21 |
2021-03-12 |
诺华股份有限公司 |
使用cd33嵌合抗原受体治疗癌症
|
TWI750110B
(zh)
|
2014-07-21 |
2021-12-21 |
瑞士商諾華公司 |
使用人類化抗-bcma嵌合抗原受體治療癌症
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
WO2016020880A2
(en)
|
2014-08-07 |
2016-02-11 |
Novartis Ag |
Angiopoietin-like 4 antibodies and methods of use
|
WO2016020882A2
(en)
|
2014-08-07 |
2016-02-11 |
Novartis Ag |
Angiopoetin-like 4 (angptl4) antibodies and methods of use
|
MY189028A
(en)
|
2014-08-19 |
2022-01-20 |
Novartis Ag |
Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
|
WO2016036916A1
(en)
|
2014-09-03 |
2016-03-10 |
Bioatla, Llc |
Discovering and producing conditionally active biologic proteins in the same eukaryotic cell production hosts
|
AU2015317608B2
(en)
|
2014-09-17 |
2021-03-11 |
Novartis Ag |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
IL308324A
(en)
|
2014-09-19 |
2024-01-01 |
Hope City |
IL13RA2-targeted chimeric antigen receptor T cells
|
CA2963935A1
(en)
|
2014-10-08 |
2016-04-14 |
Novartis Ag |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
WO2016073381A1
(en)
|
2014-11-03 |
2016-05-12 |
Cerus Corporation |
Compositions and methods for improved car-t cell therapies
|
SI3223605T1
(sl)
*
|
2014-11-24 |
2021-03-31 |
Regeneron Pharmaceuticals, Inc. |
Nehumane živali, ki izražajo humaniziran CD3 kompleks
|
CN114230664A
(zh)
|
2014-12-11 |
2022-03-25 |
皮埃尔法布雷医药公司 |
抗c10orf54抗体及其用途
|
UY36449A
(es)
|
2014-12-19 |
2016-07-29 |
Novartis Ag |
Composiciones y métodos para anticuerpos dirigidos a bmp6
|
TW201631152A
(zh)
|
2014-12-29 |
2016-09-01 |
諾華公司 |
製造嵌合抗原受體-表現細胞之方法
|
US11459390B2
(en)
|
2015-01-16 |
2022-10-04 |
Novartis Ag |
Phosphoglycerate kinase 1 (PGK) promoters and methods of use for expressing chimeric antigen receptor
|
US11161907B2
(en)
|
2015-02-02 |
2021-11-02 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
US10590182B2
(en)
|
2015-02-24 |
2020-03-17 |
The Regents Of The University Of California |
Binding-triggered transcriptional switches and methods of use thereof
|
US10195272B2
(en)
*
|
2015-03-02 |
2019-02-05 |
The Nemours Foundation |
Adoptive t-cell therapy using FcεRI-based chimeric antigen receptors for treating IgE-mediated allergic diseases
|
DE112016001013T5
(de)
|
2015-03-03 |
2017-12-21 |
Kymab Limited |
Antikörper, verwendungen und verfahren
|
US10174292B2
(en)
|
2015-03-20 |
2019-01-08 |
International Aids Vaccine Initiative |
Soluble HIV-1 envelope glycoprotein trimers
|
EP3072901A1
(en)
|
2015-03-23 |
2016-09-28 |
International Aids Vaccine Initiative |
Soluble hiv-1 envelope glycoprotein trimers
|
SI3280729T1
(sl)
|
2015-04-08 |
2022-09-30 |
Novartis Ag |
Terapije CD20, terapije CD22 in kombinacija terapij s celico, ki izraža himerni antigenski receptor CD19 (CAR)
|
ES2948133T3
(es)
|
2015-04-17 |
2023-08-31 |
Novartis Ag |
Métodos para mejorar la eficacia y expansión de células que expresan un receptor de antígeno quimérico
|
WO2016179518A2
(en)
|
2015-05-06 |
2016-11-10 |
Janssen Biotech, Inc. |
Prostate specific membrane antigen (psma) bispecific binding agents and uses thereof
|
PT3294764T
(pt)
*
|
2015-05-15 |
2021-02-15 |
Hope City |
Composições de recetores de antigénios quiméricos
|
US10434153B1
(en)
|
2015-05-20 |
2019-10-08 |
Kim Leslie O'Neill |
Use of car and bite technology coupled with an scFv from an antibody against human thymidine kinase 1 to specifically target tumors
|
BR112017021484A2
(pt)
|
2015-06-05 |
2018-07-03 |
Novartis Ag |
anticorpos de direcionamento à proteína morfogenética óssea 9 (bmp9) e métodos para os mesmos
|
JOP20200312A1
(ar)
|
2015-06-26 |
2017-06-16 |
Novartis Ag |
الأجسام المضادة للعامل xi وطرق الاستخدام
|
EP3325504A1
(en)
|
2015-07-21 |
2018-05-30 |
Novartis AG |
Methods for improving the efficacy and expansion of immune cells
|
CN108350072B
(zh)
|
2015-08-03 |
2022-05-24 |
诺华股份有限公司 |
治疗fgf21相关病症的方法
|
EP3331913A1
(en)
|
2015-08-07 |
2018-06-13 |
Novartis AG |
Treatment of cancer using chimeric cd3 receptor proteins
|
US11352439B2
(en)
*
|
2015-08-13 |
2022-06-07 |
Kim Leslie O'Neill |
Macrophage CAR (MOTO-CAR) in immunotherapy
|
CN108780084B
(zh)
|
2015-09-03 |
2022-07-22 |
诺华股份有限公司 |
预测细胞因子释放综合征的生物标志物
|
AU2016320748B2
(en)
|
2015-09-09 |
2019-05-02 |
Novartis Ag |
Thymic stromal lymphopoietin (TSLP)-binding antibodies and methods of using the antibodies
|
EP3347377B1
(en)
|
2015-09-09 |
2021-02-17 |
Novartis AG |
Thymic stromal lymphopoietin (tslp)-binding antibodies and methods of using the antibodies
|
EA201890790A1
(ru)
|
2015-09-29 |
2018-10-31 |
Селджин Корпорейшн |
Связывающие pd-1 белки и способы их применения
|
EP3371349A4
(en)
|
2015-11-02 |
2018-09-12 |
Bioatla, LLC |
Conditionally active polypeptides
|
US10144768B2
(en)
|
2015-12-04 |
2018-12-04 |
Novartis Ag |
Antibody cytokine engrafted compositions and methods of use for immunoregulation
|
US11052111B2
(en)
|
2015-12-08 |
2021-07-06 |
Chimera Bioengineering, Inc. |
Smart CAR devices and DE CAR polypeptides for treating disease and methods for enhancing immune responses
|
UY37030A
(es)
|
2015-12-18 |
2017-07-31 |
Novartis Ag |
Anticuerpos dirigidos a cd32b y métodos de uso de los mismos
|
EP3393504A1
(en)
|
2015-12-22 |
2018-10-31 |
Novartis AG |
Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
|
EP3399991A4
(en)
|
2016-01-08 |
2019-08-07 |
The Regents of The University of California |
REQUIRES ACTIVE HETERODIMER POLYPEPTIDES AND METHOD FOR USE THEREOF
|
EP3851457A1
(en)
|
2016-01-21 |
2021-07-21 |
Novartis AG |
Multispecific molecules targeting cll-1
|
EP3410849B1
(en)
|
2016-02-05 |
2023-07-05 |
Institut Pasteur |
Use of inhibitors of adam12 as adjuvants in tumor therapies
|
JP2019509322A
(ja)
|
2016-03-22 |
2019-04-04 |
バイオノミクス リミテッド |
抗lgr5モノクローナル抗体の投与
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
US11312766B2
(en)
|
2016-04-27 |
2022-04-26 |
Novartis Ag |
Antibodies against growth differentiation factor 15 and uses thereof
|
TW201802121A
(zh)
|
2016-05-25 |
2018-01-16 |
諾華公司 |
抗因子XI/XIa抗體之逆轉結合劑及其用途
|
KR102492057B1
(ko)
|
2016-06-15 |
2023-01-26 |
노파르티스 아게 |
골 형태형성 단백질 6(bmp6)의 억제제를 사용한 질병의 치료 방법
|
JP7164512B2
(ja)
|
2016-07-06 |
2022-11-01 |
ブリストル-マイヤーズ スクイブ カンパニー |
Tim-4アンタゴニストとpd-1アンタゴニストの組合せおよび使用方法
|
WO2018045177A1
(en)
|
2016-09-01 |
2018-03-08 |
Chimera Bioengineering, Inc. |
Gold optimized car t-cells
|
KR102257154B1
(ko)
|
2016-09-19 |
2021-05-28 |
셀진 코포레이션 |
Pd-1 결합 단백질을 사용하는 면역 질환의 치료 방법
|
WO2018053401A1
(en)
|
2016-09-19 |
2018-03-22 |
Celgene Corporation |
Methods of treating vitiligo using pd-1 binding proteins
|
TW202340473A
(zh)
|
2016-10-07 |
2023-10-16 |
瑞士商諾華公司 |
利用嵌合抗原受體之癌症治療
|
WO2018083248A1
(en)
|
2016-11-03 |
2018-05-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
US11168147B2
(en)
|
2016-12-23 |
2021-11-09 |
Novartis Ag |
Factor XI antibodies and methods of use
|
WO2018116267A2
(en)
|
2016-12-23 |
2018-06-28 |
Novartis Ag |
Methods of treatment with anti-factor xi/xia antibodies
|
CA3051481A1
(en)
|
2017-02-07 |
2018-08-16 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Phospholipid ether (ple) car t cell tumor targeting (ctct) agents
|
AU2018218557B9
(en)
|
2017-02-08 |
2021-06-24 |
Novartis Ag |
FGF21 mimetic antibodies and uses thereof
|
WO2018160622A1
(en)
|
2017-02-28 |
2018-09-07 |
Endocyte, Inc. |
Compositions and methods for car t cell therapy
|
MX2019011272A
(es)
|
2017-03-22 |
2019-10-24 |
Novartis Ag |
Composiciones y metodos para inmunooncologia.
|
CN110494557A
(zh)
|
2017-03-27 |
2019-11-22 |
新加坡国立大学 |
用于离体扩增和活化自然杀伤细胞的刺激细胞系
|
BR112019019917A2
(pt)
|
2017-03-27 |
2020-04-22 |
Nat Univ Singapore |
receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais
|
US10415017B2
(en)
|
2017-05-17 |
2019-09-17 |
Thunder Biotech, Inc. |
Transgenic macrophages, chimeric antigen receptors, and associated methods
|
CN111107868A
(zh)
|
2017-05-24 |
2020-05-05 |
诺华股份有限公司 |
抗体细胞因子移植蛋白及使用方法
|
JOP20190271A1
(ar)
|
2017-05-24 |
2019-11-21 |
Novartis Ag |
بروتينات مطعّمة بسيتوكين- الجسم المضاد وطرق الاستخدام للاضطرابات المتعلقة بالمناعة
|
WO2018215937A1
(en)
|
2017-05-24 |
2018-11-29 |
Novartis Ag |
Interleukin-7 antibody cytokine engrafted proteins and methods of use in the treatment of cancer
|
CA3063983A1
(en)
|
2017-05-24 |
2018-11-29 |
Novartis Ag |
Antibody-cytokine engrafted proteins and methods of use in the treatment of cancer
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
BR112020001132A2
(pt)
|
2017-07-18 |
2020-07-21 |
Calimmune, Inc. |
interruptor modulável para seleção de células doadoras modificadas
|
CN111630069B
(zh)
|
2017-10-13 |
2024-05-31 |
勃林格殷格翰国际有限公司 |
针对Thomsen-nouvelle(Tn)抗原的人抗体
|
EP3697436A1
(en)
|
2017-10-18 |
2020-08-26 |
Novartis AG |
Compositions and methods for selective protein degradation
|
WO2019081983A1
(en)
|
2017-10-25 |
2019-05-02 |
Novartis Ag |
CD32B TARGETING ANTIBODIES AND METHODS OF USE
|
CN112055595A
(zh)
|
2018-01-22 |
2020-12-08 |
恩多塞特公司 |
Car t细胞的使用方法
|
KR20200130709A
(ko)
|
2018-03-06 |
2020-11-19 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
전립선-특이 막 항원 car 및 이의 사용 방법
|
WO2019197651A1
(en)
|
2018-04-12 |
2019-10-17 |
Mediapharma S.R.L. |
Lgals3bp antibody-drug-conjugate and its use for the treatment of cancer
|
IL278630B1
(en)
|
2018-05-11 |
2024-06-01 |
Lupagen Inc |
Systems and methods for closed circuit and real-time changes of the patient's cells
|
TW202015726A
(zh)
|
2018-05-30 |
2020-05-01 |
瑞士商諾華公司 |
Entpd2抗體、組合療法、及使用該等抗體和組合療法之方法
|
BR112020024351A2
(pt)
|
2018-06-01 |
2021-02-23 |
Novartis Ag |
moléculas de ligação contra bcma e usos das mesmas
|
KR20210020932A
(ko)
|
2018-06-13 |
2021-02-24 |
노파르티스 아게 |
Bcma 키메라 항원 수용체 및 이의 용도
|
BR112021000934A2
(pt)
|
2018-07-20 |
2021-04-27 |
Pierre Fabre Medicament |
receptor para vista
|
AU2019311077A1
(en)
|
2018-07-23 |
2021-02-25 |
Heidelberg Pharma Research Gmbh |
Use of anti-CD5 antibody drug conjugate (ADC) in allogeneic cell therapy
|
UY38407A
(es)
|
2018-10-15 |
2020-05-29 |
Novartis Ag |
Anticuerpos estabilizadores de trem2
|
SG11202109057XA
(en)
|
2019-03-05 |
2021-09-29 |
Nkarta Inc |
Cd19-directed chimeric antigen receptors and uses thereof in immunotherapy
|
WO2020198731A2
(en)
|
2019-03-28 |
2020-10-01 |
Danisco Us Inc |
Engineered antibodies
|
CU20210096A7
(es)
|
2019-05-21 |
2022-06-06 |
Novartis Ag |
Moléculas de unión a cd19
|
US20230071196A1
(en)
|
2019-05-21 |
2023-03-09 |
Novartis Ag |
Variant cd58 domains and uses thereof
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與entpd2抗體之組合療法
|
CN114502590A
(zh)
|
2019-09-18 |
2022-05-13 |
诺华股份有限公司 |
Entpd2抗体、组合疗法、以及使用这些抗体和组合疗法的方法
|
IL292924A
(en)
|
2019-11-26 |
2022-07-01 |
Novartis Ag |
Chimeric antigen receptors cd19 and cd22 and their uses
|
TW202138388A
(zh)
|
2019-12-30 |
2021-10-16 |
美商西根公司 |
以非海藻糖苷化抗-cd70抗體治療癌症之方法
|
CA3166509A1
(en)
|
2020-01-14 |
2021-07-22 |
Synthekine, Inc. |
Biased il2 muteins methods and compositions
|
US20230203191A1
(en)
|
2020-03-30 |
2023-06-29 |
Danisco Us Inc |
Engineered antibodies
|
JP2023523760A
(ja)
|
2020-05-01 |
2023-06-07 |
ノバルティス アーゲー |
免疫グロブリン変異体
|
JP2023523794A
(ja)
|
2020-05-01 |
2023-06-07 |
ノバルティス アーゲー |
人工操作免疫グロブリン
|
KR20230104651A
(ko)
|
2020-11-06 |
2023-07-10 |
노파르티스 아게 |
Cd19 결합 분자 및 이의 용도
|
EP4271482A2
(en)
|
2020-12-31 |
2023-11-08 |
Alamar Biosciences, Inc. |
Binder molecules with high affinity and/ or specificity and methods of making and use thereof
|
KR20240025597A
(ko)
|
2021-06-29 |
2024-02-27 |
씨젠 인크. |
비푸코실화 항-cd70 항체 및 cd47 길항제의 조합으로 암을 치료하는 방법
|
AR128222A1
(es)
|
2022-01-07 |
2024-04-10 |
Johnson & Johnson Entpr Innovation Inc |
MATERIALES Y MÉTODOS DE PROTEÍNAS DE UNIÓN A IL-1b
|
TW202400658A
(zh)
|
2022-04-26 |
2024-01-01 |
瑞士商諾華公司 |
靶向il—13和il—18的多特異性抗體
|
WO2024015953A1
(en)
|
2022-07-15 |
2024-01-18 |
Danisco Us Inc. |
Methods for producing monoclonal antibodies
|
WO2024013727A1
(en)
|
2022-07-15 |
2024-01-18 |
Janssen Biotech, Inc. |
Material and methods for improved bioengineered pairing of antigen-binding variable regions
|
WO2024097864A1
(en)
|
2022-11-02 |
2024-05-10 |
Tigen Pharma Sa |
Expansion of lymphocytes
|
WO2024130158A1
(en)
|
2022-12-16 |
2024-06-20 |
Modernatx, Inc. |
Lipid nanoparticles and polynucleotides encoding extended serum half-life interleukin-22 for the treatment of metabolic disease
|