DE69818674D1 - Kristallmodifikation eines h-phenyl-2-pyrimidinamin-derivates, verfahren zu deren herstellung und deren anwendung - Google Patents

Kristallmodifikation eines h-phenyl-2-pyrimidinamin-derivates, verfahren zu deren herstellung und deren anwendung

Info

Publication number
DE69818674D1
DE69818674D1 DE69818674T DE69818674T DE69818674D1 DE 69818674 D1 DE69818674 D1 DE 69818674D1 DE 69818674 T DE69818674 T DE 69818674T DE 69818674 T DE69818674 T DE 69818674T DE 69818674 D1 DE69818674 D1 DE 69818674D1
Authority
DE
Germany
Prior art keywords
pyrimidinamine
derivate
phenyl
production
crystal modification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69818674T
Other languages
English (en)
Other versions
DE69818674T2 (de
Inventor
Juerg Zimmermann
Bertrand Sutter
Michael Buerger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4218028&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69818674(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE69818674D1 publication Critical patent/DE69818674D1/de
Application granted granted Critical
Publication of DE69818674T2 publication Critical patent/DE69818674T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
DE69818674T 1997-07-18 1998-07-16 Kristallmodifikation eines h-phenyl-2-pyrimidinamin-derivates, verfahren zu deren herstellung und deren anwendung Expired - Lifetime DE69818674T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH176497 1997-07-18
CH176497 1997-07-18
PCT/EP1998/004427 WO1999003854A1 (en) 1997-07-18 1998-07-16 Crystal modification of a n-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use

Publications (2)

Publication Number Publication Date
DE69818674D1 true DE69818674D1 (de) 2003-11-06
DE69818674T2 DE69818674T2 (de) 2004-08-12

Family

ID=4218028

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69818674T Expired - Lifetime DE69818674T2 (de) 1997-07-18 1998-07-16 Kristallmodifikation eines h-phenyl-2-pyrimidinamin-derivates, verfahren zu deren herstellung und deren anwendung

Country Status (31)

Country Link
US (5) US6894051B1 (de)
EP (1) EP0998473B1 (de)
JP (1) JP3276359B2 (de)
KR (1) KR100450356B1 (de)
CN (1) CN1134430C (de)
AR (2) AR016351A1 (de)
AT (1) ATE251152T1 (de)
AU (1) AU740713B2 (de)
BR (1) BR9810920A (de)
CA (1) CA2296604C (de)
CO (1) CO4940418A1 (de)
CZ (1) CZ298531B6 (de)
DE (1) DE69818674T2 (de)
DK (1) DK0998473T3 (de)
ES (1) ES2209194T3 (de)
HK (1) HK1028599A1 (de)
HU (1) HU230185B1 (de)
ID (1) ID24093A (de)
IL (5) IL133906A0 (de)
MY (2) MY128664A (de)
NO (2) NO319486B1 (de)
NZ (1) NZ502295A (de)
PE (1) PE97899A1 (de)
PL (1) PL188348B1 (de)
PT (1) PT998473E (de)
RU (1) RU2208012C2 (de)
SK (2) SK286551B6 (de)
TR (1) TR200000060T2 (de)
TW (1) TW491845B (de)
WO (1) WO1999003854A1 (de)
ZA (1) ZA986362B (de)

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