SG10201601711SA - Alkyne Substituted Quinazoline Compound And Methods Of Use - Google Patents
Alkyne Substituted Quinazoline Compound And Methods Of UseInfo
- Publication number
- SG10201601711SA SG10201601711SA SG10201601711SA SG10201601711SA SG10201601711SA SG 10201601711S A SG10201601711S A SG 10201601711SA SG 10201601711S A SG10201601711S A SG 10201601711SA SG 10201601711S A SG10201601711S A SG 10201601711SA SG 10201601711S A SG10201601711S A SG 10201601711SA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- quinazoline compound
- substituted quinazoline
- alkyne substituted
- alkyne
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161449088P | 2011-03-04 | 2011-03-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201601711SA true SG10201601711SA (en) | 2016-04-28 |
Family
ID=46798728
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013066352A SG193291A1 (en) | 2011-03-04 | 2012-03-02 | Alkyne substituted quinazoline compound and methods of use |
| SG10201601711SA SG10201601711SA (en) | 2011-03-04 | 2012-03-02 | Alkyne Substituted Quinazoline Compound And Methods Of Use |
| SG10201913982WA SG10201913982WA (en) | 2011-03-04 | 2012-03-02 | Alkyne Substituted Quinazoline Compound And Methods Of Use |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013066352A SG193291A1 (en) | 2011-03-04 | 2012-03-02 | Alkyne substituted quinazoline compound and methods of use |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201913982WA SG10201913982WA (en) | 2011-03-04 | 2012-03-02 | Alkyne Substituted Quinazoline Compound And Methods Of Use |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US9090588B2 (en) |
| EP (1) | EP2680850B1 (en) |
| JP (1) | JP6006242B2 (en) |
| KR (4) | KR20210043016A (en) |
| CN (1) | CN103998040B (en) |
| AU (3) | AU2012225693A1 (en) |
| BR (1) | BR112013022552B1 (en) |
| CA (1) | CA2828713C (en) |
| IL (1) | IL228072A (en) |
| MX (1) | MX344302B (en) |
| RU (1) | RU2013144571A (en) |
| SG (3) | SG193291A1 (en) |
| TW (1) | TWI617556B (en) |
| WO (1) | WO2012122058A2 (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG193291A1 (en) | 2011-03-04 | 2013-10-30 | Newgen Therapeutics Inc | Alkyne substituted quinazoline compound and methods of use |
| WO2012155339A1 (en) | 2011-05-17 | 2012-11-22 | 江苏康缘药业股份有限公司 | 4-phenylamino-6-butenamide-7-alkyloxy quinazoline derivatives, preparative method and use thereof |
| JP6437820B2 (en) * | 2011-07-27 | 2018-12-12 | シャンハイ ファーマシューティカルズ ホールディング カンパニー，リミティド | Quinazoline derivative, production method thereof, intermediate, composition and application thereof |
| CN104119350B (en) | 2013-04-28 | 2017-04-12 | 广东东阳光药业有限公司 | Amino quinazoline derivatives as well as salts and application method thereof |
| CN103254156B (en) * | 2013-05-10 | 2015-08-26 | 苏州明锐医药科技有限公司 | Ah method is for the preparation method of Buddhist nun's intermediate |
| CN103254183B (en) * | 2013-05-10 | 2015-11-11 | 苏州明锐医药科技有限公司 | Ah method is for the preparation method of Buddhist nun |
| CN108430972B (en) | 2015-12-24 | 2022-12-27 | 协和麒麟株式会社 | Alpha, beta-unsaturated amide compound |
| DE102016224889B4 (en) * | 2016-12-14 | 2019-11-07 | Airbus Defence and Space GmbH | A method for preventing separation of a fluid flow, flow body system and aircraft |
| US11083492B2 (en) * | 2018-06-06 | 2021-08-10 | Lifetech Scientific (Shenzhen) Co., Ltd | Method for implanting an interventional medical device |
| US10973321B2 (en) | 2018-09-04 | 2021-04-13 | Steelcase Inc. | Workspace system and components and method for the use thereof |
| CA3113241A1 (en) | 2018-09-25 | 2020-04-02 | Black Diamond Therapeutics, Inc. | Quinazoline derivatives as tyrosine kinase inhibitor, compositions, methods of making them and their use |
| CN114787150A (en) * | 2019-08-15 | 2022-07-22 | 黑钻治疗公司 | Alkynyl quinazoline compounds |
| TWI820414B (en) * | 2020-04-17 | 2023-11-01 | 大陸商北京賽特明強醫藥科技有限公司 | Quinazoline compounds, preparation method and use thereof |
| CN113527215B (en) * | 2020-04-17 | 2023-12-05 | 北京赛特明强医药科技有限公司 | Quinazoline compound, preparation method and application thereof |
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| US4343940A (en) | 1979-02-13 | 1982-08-10 | Mead Johnson & Company | Anti-tumor quinazoline compounds |
| GB2160201B (en) | 1984-06-14 | 1988-05-11 | Wyeth John & Brother Ltd | Quinazoline and cinnoline derivatives |
| DE68917485T2 (en) | 1988-01-23 | 1995-02-09 | Kyowa Hakko Kogyo Kk | Pyridazinone derivatives and pharmaceutical preparations containing them. |
| US5053227A (en) | 1989-03-22 | 1991-10-01 | Cygnus Therapeutic Systems | Skin permeation enhancer compositions, and methods and transdermal systems associated therewith |
| US5721237A (en) | 1991-05-10 | 1998-02-24 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties |
| GB9300059D0 (en) | 1992-01-20 | 1993-03-03 | Zeneca Ltd | Quinazoline derivatives |
| US6177401B1 (en) | 1992-11-13 | 2001-01-23 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften | Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis |
| GB9314893D0 (en) | 1993-07-19 | 1993-09-01 | Zeneca Ltd | Quinazoline derivatives |
| JP3089901B2 (en) | 1993-07-20 | 2000-09-18 | 株式会社豊田自動織機製作所 | Power transmission structure in clutchless compressor |
| WO1995024190A2 (en) | 1994-03-07 | 1995-09-14 | Sugen, Inc. | Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof |
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| AU5108196A (en) | 1995-03-20 | 1996-10-08 | Dr. Karl Thomae Gmbh | Imidazoquinazolines, drugs containing these compounds, their use and process for their preparation |
| CA2216796C (en) | 1995-03-30 | 2003-09-02 | Pfizer Inc. | Quinazoline derivatives |
| GB9508538D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| IL117923A (en) | 1995-05-03 | 2000-06-01 | Warner Lambert Co | Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds |
| ATE182148T1 (en) | 1995-05-12 | 1999-07-15 | Neurogen Corp | NEW DEAZAPURINE DERIVATIVES; A NEW CLASS OF CRF1-SPECIFIC LIGANDS |
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| UA74803C2 (en) | 1999-11-11 | 2006-02-15 | Осі Фармасьютікалз, Інк. | A stable polymorph of n-(3-ethynylphenyl)-6,7-bis(2-methoxyetoxy)-4-quinazolinamine hydrochloride, a method for producing thereof (variants) and pharmaceutical use |
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| JP5580592B2 (en) | 2006-09-11 | 2014-08-27 | キュリス，インコーポレイテッド | Quinazoline-based EGFR inhibitors containing zinc binding moieties |
| WO2008119663A1 (en) | 2007-03-29 | 2008-10-09 | F. Hoffmann-La Roche Ag | Heterocyclic antiviral compounds |
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| CN105037333A (en) | 2009-12-21 | 2015-11-11 | 张强 | Novel quinazoline derivatives |
| US20120195857A1 (en) | 2010-08-12 | 2012-08-02 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| CN102382106A (en) | 2010-08-30 | 2012-03-21 | 黄振华 | Aniline substituted quinazoline derivative |
| SG193291A1 (en) | 2011-03-04 | 2013-10-30 | Newgen Therapeutics Inc | Alkyne substituted quinazoline compound and methods of use |
| WO2012155339A1 (en) | 2011-05-17 | 2012-11-22 | 江苏康缘药业股份有限公司 | 4-phenylamino-6-butenamide-7-alkyloxy quinazoline derivatives, preparative method and use thereof |
-
2012
- 2012-03-02 SG SG2013066352A patent/SG193291A1/en unknown
- 2012-03-02 KR KR1020217010767A patent/KR20210043016A/en not_active Application Discontinuation
- 2012-03-02 MX MX2013010016A patent/MX344302B/en active IP Right Grant
- 2012-03-02 BR BR112013022552-1A patent/BR112013022552B1/en active IP Right Grant
- 2012-03-02 CA CA2828713A patent/CA2828713C/en active Active
- 2012-03-02 SG SG10201601711SA patent/SG10201601711SA/en unknown
- 2012-03-02 WO PCT/US2012/027614 patent/WO2012122058A2/en active Application Filing
- 2012-03-02 SG SG10201913982WA patent/SG10201913982WA/en unknown
- 2012-03-02 RU RU2013144571/04A patent/RU2013144571A/en not_active Application Discontinuation
- 2012-03-02 US US14/002,983 patent/US9090588B2/en active Active
- 2012-03-02 EP EP12754325.4A patent/EP2680850B1/en active Active
- 2012-03-02 KR KR1020137026199A patent/KR102061743B1/en active IP Right Grant
- 2012-03-02 AU AU2012225693A patent/AU2012225693A1/en not_active Abandoned
- 2012-03-02 JP JP2013556664A patent/JP6006242B2/en active Active
- 2012-03-02 KR KR1020227006071A patent/KR20220031732A/en not_active Application Discontinuation
- 2012-03-02 CN CN201280011384.6A patent/CN103998040B/en active Active
- 2012-03-02 KR KR1020197038395A patent/KR20200003933A/en not_active Application Discontinuation
- 2012-03-03 TW TW101107247A patent/TWI617556B/en active
-
2013
- 2013-08-22 IL IL228072A patent/IL228072A/en active IP Right Grant
-
2015
- 2015-06-19 US US14/745,308 patent/US20160031860A1/en not_active Abandoned
-
2017
- 2017-02-14 AU AU2017200984A patent/AU2017200984A1/en not_active Abandoned
- 2017-08-11 US US15/675,438 patent/US20180093975A1/en not_active Abandoned
-
2018
- 2018-11-22 AU AU2018267622A patent/AU2018267622B2/en active Active
-
2019
- 2019-01-18 US US16/252,458 patent/US20190382382A1/en not_active Abandoned
-
2020
- 2020-03-27 US US16/833,020 patent/US11524956B2/en active Active
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