DE69427104T2 - Quinazoline Derivate und ihre Anwendung als Krebsmittel - Google Patents

Quinazoline Derivate und ihre Anwendung als Krebsmittel

Info

Publication number
DE69427104T2
DE69427104T2 DE69427104T DE69427104T DE69427104T2 DE 69427104 T2 DE69427104 T2 DE 69427104T2 DE 69427104 T DE69427104 T DE 69427104T DE 69427104 T DE69427104 T DE 69427104T DE 69427104 T2 DE69427104 T2 DE 69427104T2
Authority
DE
Germany
Prior art keywords
quinazoline derivatives
cancer drugs
halogeno
amino
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69427104T
Other languages
English (en)
Other versions
DE69427104D1 (de
Inventor
Andrew John Barker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE69427104D1 publication Critical patent/DE69427104D1/de
Publication of DE69427104T2 publication Critical patent/DE69427104T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69427104T 1993-07-19 1994-07-15 Quinazoline Derivate und ihre Anwendung als Krebsmittel Expired - Fee Related DE69427104T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939314893A GB9314893D0 (en) 1993-07-19 1993-07-19 Quinazoline derivatives

Publications (2)

Publication Number Publication Date
DE69427104D1 DE69427104D1 (de) 2001-05-23
DE69427104T2 true DE69427104T2 (de) 2001-10-31

Family

ID=10739032

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427104T Expired - Fee Related DE69427104T2 (de) 1993-07-19 1994-07-15 Quinazoline Derivate und ihre Anwendung als Krebsmittel

Country Status (15)

Country Link
US (1) US5475001A (de)
EP (1) EP0635498B1 (de)
JP (1) JP3545763B2 (de)
AT (1) ATE200667T1 (de)
AU (1) AU7191694A (de)
DE (1) DE69427104T2 (de)
DK (1) DK0635498T3 (de)
ES (1) ES2156137T3 (de)
GB (2) GB9314893D0 (de)
GR (1) GR3035890T3 (de)
IL (1) IL110164A (de)
PT (1) PT635498E (de)
TW (1) TW270117B (de)
WO (1) WO1995003283A1 (de)
ZA (1) ZA945156B (de)

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GB9314893D0 (en) 1993-09-01
TW270117B (en) 1996-02-11
IL110164A (en) 2000-09-28
PT635498E (pt) 2001-08-30
AU7191694A (en) 1995-02-20
GR3035890T3 (en) 2001-08-31
ES2156137T3 (es) 2001-06-16
DK0635498T3 (da) 2001-05-07
ATE200667T1 (de) 2001-05-15
EP0635498B1 (de) 2001-04-18
EP0635498A1 (de) 1995-01-25
GB9414341D0 (en) 1994-09-07
US5475001A (en) 1995-12-12
DE69427104D1 (de) 2001-05-23
WO1995003283A1 (en) 1995-02-02
JP3545763B2 (ja) 2004-07-21
JPH09500636A (ja) 1997-01-21
IL110164A0 (en) 1994-10-07
ZA945156B (en) 1995-01-19

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