DE3855852D1 - Kugelförmige Granula mit Kern sowie deren Herstellung - Google Patents

Kugelförmige Granula mit Kern sowie deren Herstellung

Info

Publication number
DE3855852D1
DE3855852D1 DE3855852T DE3855852T DE3855852D1 DE 3855852 D1 DE3855852 D1 DE 3855852D1 DE 3855852 T DE3855852 T DE 3855852T DE 3855852 T DE3855852 T DE 3855852T DE 3855852 D1 DE3855852 D1 DE 3855852D1
Authority
DE
Germany
Prior art keywords
core
spherical granules
manufacture
granules
coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3855852T
Other languages
English (en)
Other versions
DE3855852T2 (de
Inventor
Tadashi Makino
Tetsuro Tabata
Shin-Ichiro Hirai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11992094&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3855852(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE3855852D1 publication Critical patent/DE3855852D1/de
Publication of DE3855852T2 publication Critical patent/DE3855852T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cereal-Derived Products (AREA)
DE3855852T 1987-01-29 1988-01-25 Kugelförmige Granula mit Kern sowie deren Herstellung Expired - Lifetime DE3855852T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1917887 1987-01-29

Publications (2)

Publication Number Publication Date
DE3855852D1 true DE3855852D1 (de) 1997-05-07
DE3855852T2 DE3855852T2 (de) 1997-07-17

Family

ID=11992094

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8888300569T Expired - Lifetime DE3874360T2 (de) 1987-01-29 1988-01-25 Kugelfoermige granula mit kern sowie deren herstellung.
DE3855852T Expired - Lifetime DE3855852T2 (de) 1987-01-29 1988-01-25 Kugelförmige Granula mit Kern sowie deren Herstellung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE8888300569T Expired - Lifetime DE3874360T2 (de) 1987-01-29 1988-01-25 Kugelfoermige granula mit kern sowie deren herstellung.

Country Status (9)

Country Link
US (2) US5026560A (de)
EP (2) EP0277741B1 (de)
KR (1) KR960005138B1 (de)
AT (1) ATE150963T1 (de)
CA (1) CA1312548C (de)
DE (2) DE3874360T2 (de)
ES (2) ES2099130T3 (de)
GR (1) GR3006170T3 (de)
HU (1) HU198396B (de)

Families Citing this family (237)

* Cited by examiner, † Cited by third party
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HU198396B (en) 1989-10-30
EP0277741B1 (de) 1992-09-09
ES2052697T3 (es) 1994-07-16
ATE150963T1 (de) 1997-04-15
DE3855852T2 (de) 1997-07-17
HUT46238A (en) 1988-10-28
GR3006170T3 (de) 1993-06-21
DE3874360D1 (de) 1992-10-15
ES2099130T3 (es) 1997-05-16
EP0475536B1 (de) 1997-04-02
US5516531A (en) 1996-05-14
US5026560A (en) 1991-06-25
DE3874360T2 (de) 1993-01-14
EP0475536A1 (de) 1992-03-18
KR960005138B1 (ko) 1996-04-22
CA1312548C (en) 1993-01-12
KR880008803A (ko) 1988-09-13

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