DE3448145C2 - - Google Patents
Info
- Publication number
- DE3448145C2 DE3448145C2 DE3448145A DE3448145A DE3448145C2 DE 3448145 C2 DE3448145 C2 DE 3448145C2 DE 3448145 A DE3448145 A DE 3448145A DE 3448145 A DE3448145 A DE 3448145A DE 3448145 C2 DE3448145 C2 DE 3448145C2
- Authority
- DE
- Germany
- Prior art keywords
- glycoprotein
- molecular weight
- extract
- administered
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108090000288 Glycoproteins Proteins 0.000 claims description 45
- 102000003886 Glycoproteins Human genes 0.000 claims description 45
- 239000000126 substance Substances 0.000 claims description 18
- 102000004169 proteins and genes Human genes 0.000 claims description 10
- 108090000623 proteins and genes Proteins 0.000 claims description 10
- 201000001474 proteinuria Diseases 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 241000222355 Trametes versicolor Species 0.000 claims description 8
- 239000000284 extract Substances 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 4
- 239000012670 alkaline solution Substances 0.000 claims description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 16
- 239000000203 mixture Substances 0.000 description 12
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- 230000000694 effects Effects 0.000 description 8
- 229910052757 nitrogen Inorganic materials 0.000 description 8
- 206010029164 Nephrotic syndrome Diseases 0.000 description 7
- 208000009928 nephrosis Diseases 0.000 description 7
- 239000000825 pharmaceutical preparation Substances 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 5
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- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
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- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 229960005205 prednisolone Drugs 0.000 description 3
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 241000974482 Aricia saepiolus Species 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0.000 description 2
- 208000005777 Lupus Nephritis Diseases 0.000 description 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
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- 239000001257 hydrogen Substances 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 description 2
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- 239000002504 physiological saline solution Substances 0.000 description 2
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- 208000024891 symptom Diseases 0.000 description 2
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- 238000005406 washing Methods 0.000 description 2
- 239000003643 water by type Substances 0.000 description 2
- AZUYLZMQTIKGSC-UHFFFAOYSA-N 1-[6-[4-(5-chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methylindazol-5-yl)pyrazol-1-yl]-2-azaspiro[3.3]heptan-2-yl]prop-2-en-1-one Chemical compound ClC=1C(=C2C=NNC2=CC=1C)C=1C(=NN(C=1C)C1CC2(CN(C2)C(C=C)=O)C1)C=1C=C2C=NN(C2=CC=1)C AZUYLZMQTIKGSC-UHFFFAOYSA-N 0.000 description 1
- MYKOKMFESWKQRX-UHFFFAOYSA-N 10h-anthracen-9-one;sulfuric acid Chemical compound OS(O)(=O)=O.C1=CC=C2C(=O)C3=CC=CC=C3CC2=C1 MYKOKMFESWKQRX-UHFFFAOYSA-N 0.000 description 1
- RYSMHWILUNYBFW-GRIPGOBMSA-N 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine Chemical compound C1=NC=2C(N(C)C)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](N)[C@H]1O RYSMHWILUNYBFW-GRIPGOBMSA-N 0.000 description 1
- 241000221198 Basidiomycota Species 0.000 description 1
- 241000222356 Coriolus Species 0.000 description 1
- 206010060891 General symptom Diseases 0.000 description 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 238000007696 Kjeldahl method Methods 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 description 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 description 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010039491 Sarcoma Diseases 0.000 description 1
- 208000006268 Sarcoma 180 Diseases 0.000 description 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 238000005903 acid hydrolysis reaction Methods 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 229940041181 antineoplastic drug Drugs 0.000 description 1
- 235000003704 aspartic acid Nutrition 0.000 description 1
- 238000011888 autopsy Methods 0.000 description 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
- 229960002537 betamethasone Drugs 0.000 description 1
- UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 229960004397 cyclophosphamide Drugs 0.000 description 1
- 229960003957 dexamethasone Drugs 0.000 description 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 229960002768 dipyridamole Drugs 0.000 description 1
- IZEKFCXSFNUWAM-UHFFFAOYSA-N dipyridamole Chemical compound C=12N=C(N(CCO)CCO)N=C(N3CCCCC3)C2=NC(N(CCO)CCO)=NC=1N1CCCCC1 IZEKFCXSFNUWAM-UHFFFAOYSA-N 0.000 description 1
- -1 disintegrators Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000010200 folin Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 150000004676 glycans Chemical group 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 244000005709 gut microbiome Species 0.000 description 1
- 239000007902 hard capsule Substances 0.000 description 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 description 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 description 1
- HHIVCXLCMPHUSC-UHFFFAOYSA-N hydron;1h-indol-1-ium;sulfate Chemical compound OS(O)(=O)=O.C1=CC=C2NC=CC2=C1 HHIVCXLCMPHUSC-UHFFFAOYSA-N 0.000 description 1
- 229960000905 indomethacin Drugs 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000010255 intramuscular injection Methods 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 239000007951 isotonicity adjuster Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 230000036244 malformation Effects 0.000 description 1
- HFOJRTIFHRRHGA-UHFFFAOYSA-N naphthalen-1-ol;sulfuric acid Chemical compound OS(O)(=O)=O.C1=CC=C2C(O)=CC=CC2=C1 HFOJRTIFHRRHGA-UHFFFAOYSA-N 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- OQUKIQWCVTZJAF-UHFFFAOYSA-N phenol;sulfuric acid Chemical compound OS(O)(=O)=O.OC1=CC=CC=C1 OQUKIQWCVTZJAF-UHFFFAOYSA-N 0.000 description 1
- 108010001062 polysaccharide-K Proteins 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/375—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Basidiomycetes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58147239A JPS6045524A (ja) | 1983-08-11 | 1983-08-11 | 抗炎症剤 |
| JP58147237A JPS6045523A (ja) | 1983-08-11 | 1983-08-11 | 解熱鎮痛剤 |
| JP58147240A JPS6045530A (ja) | 1983-08-11 | 1983-08-11 | ネフロ−ゼ症候群改善剤 |
| JP58147231A JPS6045532A (ja) | 1983-08-11 | 1983-08-11 | 血糖降下剤 |
| JP58147238A JPS6045531A (ja) | 1983-08-11 | 1983-08-11 | 抗高脂血症剤 |
| JP58147234A JPS6045528A (ja) | 1983-08-11 | 1983-08-11 | 虚血性脳疾患改善剤 |
| JP58147236A JPS6045529A (ja) | 1983-08-11 | 1983-08-11 | 抗血栓症剤 |
| JP58147232A JPS6045525A (ja) | 1983-08-11 | 1983-08-11 | 抗リウマチ剤 |
| JP58147233A JPS6045526A (ja) | 1983-08-11 | 1983-08-11 | 虚血性心疾患改善剤 |
| JP58147235A JPS6045527A (ja) | 1983-08-11 | 1983-08-11 | 血圧降下剤 |
| JP58147241A JPS6045533A (ja) | 1983-08-11 | 1983-08-11 | プロスタグランジン調節剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3448145C2 true DE3448145C2 (en, 2012) | 1989-09-21 |
Family
ID=27582198
Family Applications (11)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3448145A Expired DE3448145C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448153A Expired DE3448153C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448152A Expired DE3448152C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448151A Expired DE3448151C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448149A Expired - Fee Related DE3448149C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448144A Expired DE3448144C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448150A Expired DE3448150C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE19843429551 Granted DE3429551A1 (de) | 1983-08-11 | 1984-08-10 | Pharmazeutische zubereitung, die ein glycoprotein enthaelt |
| DE3448154A Expired DE3448154C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448148A Expired DE3448148C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448155A Expired DE3448155C2 (en, 2012) | 1983-08-11 | 1984-08-10 |
Family Applications After (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3448153A Expired DE3448153C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448152A Expired DE3448152C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448151A Expired DE3448151C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448149A Expired - Fee Related DE3448149C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448144A Expired DE3448144C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448150A Expired DE3448150C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE19843429551 Granted DE3429551A1 (de) | 1983-08-11 | 1984-08-10 | Pharmazeutische zubereitung, die ein glycoprotein enthaelt |
| DE3448154A Expired DE3448154C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448148A Expired DE3448148C2 (en, 2012) | 1983-08-11 | 1984-08-10 | |
| DE3448155A Expired DE3448155C2 (en, 2012) | 1983-08-11 | 1984-08-10 |
Country Status (2)
| Country | Link |
|---|---|
| US (2) | US4820689A (en, 2012) |
| DE (11) | DE3448145C2 (en, 2012) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3639561A1 (de) * | 1986-11-20 | 1988-06-01 | Baumann Hanno | Verfahren zur herstellung von nicht-thrombogenen substraten |
| JPH0643336B2 (ja) * | 1988-06-30 | 1994-06-08 | 呉羽化学工業株式会社 | 血管増殖抑制剤 |
| DE3942081A1 (de) * | 1989-12-20 | 1991-06-27 | Behringwerke Ag | Mittel zur verbesserung der wiederfindung von annexinen |
| US5393742A (en) * | 1990-08-30 | 1995-02-28 | Mect Corporation | Preparation for treating renal disease |
| JPH0737990B2 (ja) * | 1990-10-12 | 1995-04-26 | 寳酒造株式会社 | 糖類の標識方法及び糖類標識用キット |
| WO1994012199A1 (en) * | 1992-11-30 | 1994-06-09 | Department Of The Army | Purified coriolus versicolor polypeptide complex |
| DE69423806T2 (de) * | 1993-01-22 | 2000-08-17 | Kanegafuchi Chemical Ind | Therapeutisches Agens für NIDDM |
| JP3960393B2 (ja) * | 1994-06-30 | 2007-08-15 | 明治乳業株式会社 | 健康組成物 |
| JPH08208704A (ja) * | 1995-02-06 | 1996-08-13 | Kureha Chem Ind Co Ltd | 新規な糖タンパク質複合体、その製造方法、並びに抗腫瘍剤、免疫調節剤及び増殖因子阻害剤 |
| US6379714B1 (en) * | 1995-04-14 | 2002-04-30 | Pharmaprint, Inc. | Pharmaceutical grade botanical drugs |
| WO2001056589A2 (en) * | 2000-01-31 | 2001-08-09 | Tadashi Goino | Physiologically active compositions of basidiomycotina and araliaceae extracts |
| JP4561098B2 (ja) * | 2001-06-01 | 2010-10-13 | 味の素株式会社 | 糖尿病用薬剤 |
| US7048932B2 (en) * | 2002-05-22 | 2006-05-23 | The Chinese University Of Hong Kong | Preparation and standardization of immunomodulatory peptide-linked glucans with verifiable oral absorbability from coriolus versicolor |
| JP4587442B2 (ja) * | 2004-02-12 | 2010-11-24 | 株式会社クレハ | 新規な高脂血症治療剤および食品 |
| EP1918363B1 (en) * | 2005-07-28 | 2016-09-28 | Nikken Sohonsha Corporation | Strain of turkey tail mushroom, extract from the same, and use of the same |
| KR100852479B1 (ko) | 2007-01-26 | 2008-08-18 | 대구대학교 산학협력단 | 혈당강하 효과를 갖는 운지버섯 유래 다당체 및 그 제조방법 |
| CN105597080A (zh) * | 2016-01-29 | 2016-05-25 | 程潜 | 一种用于治疗尿毒症和尿蛋白的药物 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2659808B2 (de) * | 1976-01-01 | 1979-08-02 | Kureha Kagaku Kogyo K.K., Tokio | Proteingebundene Polysaccharide und deren Verwendung zur Bekämpfung von Tumoren |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3929994A (en) * | 1969-05-20 | 1975-12-30 | Roussel Uclaf | Anti-inflammatory glycoprotein compositions and method of use |
| JPS5290614A (en) * | 1975-12-18 | 1977-07-30 | Kureha Chem Ind Co Ltd | Preparation of anti-tumor substance |
| JPS536412A (en) * | 1976-07-07 | 1978-01-20 | Kureha Chem Ind Co Ltd | Preparation of n-containing polysaccharides |
| JPS536413A (en) * | 1976-07-07 | 1978-01-20 | Kureha Chem Ind Co Ltd | Preparation of n-containing polysaccharides |
| JPS5315495A (en) * | 1976-07-22 | 1978-02-13 | Kureha Chem Ind Co Ltd | Preparation of polysaccharides |
| US4268505A (en) * | 1978-04-13 | 1981-05-19 | Kureha Kagaku Kogyo Kabushiki Kaisha | Pharmaceutical composition comprising a nitrogen-containing polysaccharide and an antibiotic agent, and a method of treating an infectious disease therewith |
| JPS5851263B2 (ja) * | 1979-07-16 | 1983-11-15 | コニカ株式会社 | 熱ロ−ラ型定着装置 |
| JPS5614276A (en) * | 1979-07-17 | 1981-02-12 | Toshiba Corp | Flash fixing device |
| JPS5639288A (en) * | 1979-09-07 | 1981-04-14 | Mitsui Constr | Drilling machine for locking bolt for pit |
| JPS5932480B2 (ja) * | 1981-02-10 | 1984-08-09 | 呉羽化学工業株式会社 | 新規な糖蛋白複合体 |
| JPH05136322A (ja) * | 1991-11-11 | 1993-06-01 | Mitsubishi Electric Corp | 半導体装置 |
-
1984
- 1984-08-10 DE DE3448145A patent/DE3448145C2/de not_active Expired
- 1984-08-10 DE DE3448153A patent/DE3448153C2/de not_active Expired
- 1984-08-10 DE DE3448152A patent/DE3448152C2/de not_active Expired
- 1984-08-10 DE DE3448151A patent/DE3448151C2/de not_active Expired
- 1984-08-10 DE DE3448149A patent/DE3448149C2/de not_active Expired - Fee Related
- 1984-08-10 DE DE3448144A patent/DE3448144C2/de not_active Expired
- 1984-08-10 DE DE3448150A patent/DE3448150C2/de not_active Expired
- 1984-08-10 DE DE19843429551 patent/DE3429551A1/de active Granted
- 1984-08-10 DE DE3448154A patent/DE3448154C2/de not_active Expired
- 1984-08-10 DE DE3448148A patent/DE3448148C2/de not_active Expired
- 1984-08-10 DE DE3448155A patent/DE3448155C2/de not_active Expired
-
1986
- 1986-08-22 US US06/898,900 patent/US4820689A/en not_active Expired - Fee Related
-
1988
- 1988-12-16 US US07/285,664 patent/US5008243A/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2659808B2 (de) * | 1976-01-01 | 1979-08-02 | Kureha Kagaku Kogyo K.K., Tokio | Proteingebundene Polysaccharide und deren Verwendung zur Bekämpfung von Tumoren |
Non-Patent Citations (2)
| Title |
|---|
| Firmenschrift der Ain aus dem Jahr 1977, Qutline of PKS, S.28-30 * |
| JP 57-134 496 (Abstract) * |
Also Published As
| Publication number | Publication date |
|---|---|
| DE3448144C2 (en, 2012) | 1989-10-05 |
| DE3448148C2 (en, 2012) | 1989-09-21 |
| DE3429551A1 (de) | 1985-02-21 |
| DE3448154C2 (en, 2012) | 1989-11-02 |
| DE3429551C2 (en, 2012) | 1989-09-21 |
| DE3448152C2 (en, 2012) | 1989-11-02 |
| US4820689A (en) | 1989-04-11 |
| DE3448155C2 (en, 2012) | 1989-11-02 |
| DE3448150C2 (en, 2012) | 1989-11-02 |
| DE3448153C2 (en, 2012) | 1989-11-02 |
| DE3448151C2 (en, 2012) | 1989-11-02 |
| DE3448149C2 (en, 2012) | 1990-01-04 |
| US5008243A (en) | 1991-04-16 |
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