DE3321127A1 - Neues verfahren zur herstellung von 2-(2-aminothiazol-4-yl)-glyoxylsaeure-derivaten oder eines salzes derselben sowie zwischenprodukte derselben und verfahren zur herstellung der zwischenprodukte - Google Patents
Neues verfahren zur herstellung von 2-(2-aminothiazol-4-yl)-glyoxylsaeure-derivaten oder eines salzes derselben sowie zwischenprodukte derselben und verfahren zur herstellung der zwischenprodukteInfo
- Publication number
- DE3321127A1 DE3321127A1 DE19833321127 DE3321127A DE3321127A1 DE 3321127 A1 DE3321127 A1 DE 3321127A1 DE 19833321127 DE19833321127 DE 19833321127 DE 3321127 A DE3321127 A DE 3321127A DE 3321127 A1 DE3321127 A1 DE 3321127A1
- Authority
- DE
- Germany
- Prior art keywords
- salt
- stands
- general formula
- group
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
- C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
- C07C45/81—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
- C07C45/82—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation by distillation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/16—Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57103108A JPS58222048A (ja) | 1982-06-17 | 1982-06-17 | 1―ブロモ―4―クロロブタン―2,3―ジオン |
JP57103109A JPS58222076A (ja) | 1982-06-17 | 1982-06-17 | 2−アミノチアゾ−ル誘導体 |
JP58078201A JPS59204179A (ja) | 1983-05-06 | 1983-05-06 | 2―(2―アミノチアゾール―4―イル)グリオキシル酸誘導体またはその塩の製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3321127A1 true DE3321127A1 (de) | 1983-12-22 |
DE3321127C2 DE3321127C2 (en, 2012) | 1988-06-01 |
Family
ID=27302641
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19833321127 Granted DE3321127A1 (de) | 1982-06-17 | 1983-06-10 | Neues verfahren zur herstellung von 2-(2-aminothiazol-4-yl)-glyoxylsaeure-derivaten oder eines salzes derselben sowie zwischenprodukte derselben und verfahren zur herstellung der zwischenprodukte |
DE3348173A Expired DE3348173C2 (en, 2012) | 1982-06-17 | 1983-06-10 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3348173A Expired DE3348173C2 (en, 2012) | 1982-06-17 | 1983-06-10 |
Country Status (21)
Country | Link |
---|---|
US (2) | US4563534A (en, 2012) |
KR (1) | KR860001027B1 (en, 2012) |
AT (1) | AT380877B (en, 2012) |
AU (1) | AU542287B2 (en, 2012) |
BE (1) | BE897063A (en, 2012) |
CA (1) | CA1191512A (en, 2012) |
DE (2) | DE3321127A1 (en, 2012) |
DK (3) | DK161073C (en, 2012) |
ES (3) | ES8502697A1 (en, 2012) |
FI (1) | FI85470C (en, 2012) |
FR (3) | FR2528839B1 (en, 2012) |
GB (2) | GB2122988B (en, 2012) |
IL (1) | IL68931A0 (en, 2012) |
IT (1) | IT1171839B (en, 2012) |
MX (1) | MX156981A (en, 2012) |
NL (1) | NL8302151A (en, 2012) |
NO (1) | NO161114C (en, 2012) |
NZ (1) | NZ204609A (en, 2012) |
PH (3) | PH18261A (en, 2012) |
PT (1) | PT76880B (en, 2012) |
SE (3) | SE452981B (en, 2012) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3321127A1 (de) | 1982-06-17 | 1983-12-22 | Toyama Chemical Co. Ltd., Tokyo | Neues verfahren zur herstellung von 2-(2-aminothiazol-4-yl)-glyoxylsaeure-derivaten oder eines salzes derselben sowie zwischenprodukte derselben und verfahren zur herstellung der zwischenprodukte |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU567990B2 (en) * | 1982-06-17 | 1987-12-10 | Toyama Chemical Co. Ltd. | Halogenated vicinal diketones |
DE3412293A1 (de) * | 1984-04-03 | 1985-10-03 | Basf Ag, 6700 Ludwigshafen | Thiazolderivate |
US5484928A (en) * | 1984-04-10 | 1996-01-16 | Biochemie Gesellschaft M.B.H. | 2-(2-aminothiazol-4-yl)-2-oxoacetic acid derivatives |
EP0407651A3 (en) * | 1989-07-10 | 1991-08-07 | J. Uriach & Cia. S.A. | Use of 1,3-diisobutyl-8-methylxanthine as a bronchodilator and antiallergy agent |
EP3405011A1 (en) * | 2017-05-16 | 2018-11-21 | Arjo Wiggins Fine Papers Limited | Paper-in-resin electronics - process for producing it and application in manufactured products |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2710902A1 (de) * | 1977-03-12 | 1978-09-21 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
EP0034340A1 (de) * | 1980-02-18 | 1981-08-26 | Lonza Ag | Verfahren zur Herstellung von (2-Aminothiazol-4-yl)-Essigsäurehydrochlorid |
DE3105136A1 (de) * | 1980-02-12 | 1981-12-10 | Rhône-Poulenc Industries, 75008 Paris | "neue thioloester, ihre herstellung und ihre verwendung zur synthese" |
EP0050458A2 (en) * | 1980-10-14 | 1982-04-28 | Pfizer Inc. | 2-Guanidino-4-heteroarylthiazoles and pharmaceutical compositions containing them |
DE3321127A1 (de) | 1982-06-17 | 1983-12-22 | Toyama Chemical Co. Ltd., Tokyo | Neues verfahren zur herstellung von 2-(2-aminothiazol-4-yl)-glyoxylsaeure-derivaten oder eines salzes derselben sowie zwischenprodukte derselben und verfahren zur herstellung der zwischenprodukte |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2821555A (en) * | 1957-01-07 | 1958-01-28 | Dow Chemical Co | 1-bromo-2, 3-butanedione and its 3-oxime derivative |
US4191762A (en) * | 1974-03-14 | 1980-03-04 | Fujisawa Pharmaceutical Co., Ltd. | 2-Lower alkyl-7-substituted amino-2 or 3-cephem-4-carboxylic acid compounds |
US4390534A (en) * | 1978-12-29 | 1983-06-28 | Fujisawa Pharmaceutical Co., Ltd. | Cephem and cepham compounds |
US4308391A (en) * | 1979-10-01 | 1981-12-29 | Monsanto Company | 2-Amino-4-substituted-thiazolecarboxylic acids and their derivatives |
-
1983
- 1983-06-08 GB GB08315700A patent/GB2122988B/en not_active Expired
- 1983-06-08 AU AU15500/83A patent/AU542287B2/en not_active Ceased
- 1983-06-09 IL IL68931A patent/IL68931A0/xx not_active IP Right Cessation
- 1983-06-09 CA CA000430079A patent/CA1191512A/en not_active Expired
- 1983-06-10 DE DE19833321127 patent/DE3321127A1/de active Granted
- 1983-06-10 DE DE3348173A patent/DE3348173C2/de not_active Expired
- 1983-06-14 US US06/504,317 patent/US4563534A/en not_active Expired - Fee Related
- 1983-06-14 AT AT0219783A patent/AT380877B/de active
- 1983-06-14 FI FI832152A patent/FI85470C/fi not_active IP Right Cessation
- 1983-06-15 FR FR8309863A patent/FR2528839B1/fr not_active Expired
- 1983-06-15 IT IT48504/83A patent/IT1171839B/it active
- 1983-06-16 ES ES523348A patent/ES8502697A1/es not_active Expired
- 1983-06-16 NL NL8302151A patent/NL8302151A/nl not_active Application Discontinuation
- 1983-06-16 NZ NZ204609A patent/NZ204609A/en unknown
- 1983-06-16 MX MX83197676A patent/MX156981A/es unknown
- 1983-06-16 PH PH29065A patent/PH18261A/en unknown
- 1983-06-16 PT PT76880A patent/PT76880B/pt not_active IP Right Cessation
- 1983-06-16 BE BE0/211013A patent/BE897063A/fr not_active IP Right Cessation
- 1983-06-16 DK DK278883A patent/DK161073C/da not_active IP Right Cessation
- 1983-06-16 SE SE8303465A patent/SE452981B/sv not_active IP Right Cessation
- 1983-06-16 KR KR1019830002682A patent/KR860001027B1/ko not_active Expired
- 1983-06-16 NO NO832178A patent/NO161114C/no unknown
-
1984
- 1984-01-13 FR FR8400471A patent/FR2540873B1/fr not_active Expired
- 1984-01-13 FR FR848400472A patent/FR2540860B1/fr not_active Expired
- 1984-03-01 ES ES530213A patent/ES8506572A1/es not_active Expired
- 1984-03-01 ES ES530212A patent/ES530212A0/es active Granted
- 1984-09-07 PH PH31192A patent/PH20516A/en unknown
- 1984-09-07 PH PH31191A patent/PH19985A/en unknown
-
1985
- 1985-07-09 US US06/753,068 patent/US4667040A/en not_active Expired - Fee Related
- 1985-07-22 GB GB08518464A patent/GB2167410B/en not_active Expired
-
1987
- 1987-03-23 SE SE8701193A patent/SE8701193L/xx not_active Application Discontinuation
- 1987-03-23 SE SE8701192A patent/SE8701192D0/xx not_active Application Discontinuation
-
1990
- 1990-09-21 DK DK229090A patent/DK163582C/da active
- 1990-09-21 DK DK229190A patent/DK163816C/da not_active IP Right Cessation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2710902A1 (de) * | 1977-03-12 | 1978-09-21 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
DE3105136A1 (de) * | 1980-02-12 | 1981-12-10 | Rhône-Poulenc Industries, 75008 Paris | "neue thioloester, ihre herstellung und ihre verwendung zur synthese" |
EP0034340A1 (de) * | 1980-02-18 | 1981-08-26 | Lonza Ag | Verfahren zur Herstellung von (2-Aminothiazol-4-yl)-Essigsäurehydrochlorid |
EP0050458A2 (en) * | 1980-10-14 | 1982-04-28 | Pfizer Inc. | 2-Guanidino-4-heteroarylthiazoles and pharmaceutical compositions containing them |
DE3321127A1 (de) | 1982-06-17 | 1983-12-22 | Toyama Chemical Co. Ltd., Tokyo | Neues verfahren zur herstellung von 2-(2-aminothiazol-4-yl)-glyoxylsaeure-derivaten oder eines salzes derselben sowie zwischenprodukte derselben und verfahren zur herstellung der zwischenprodukte |
Non-Patent Citations (4)
Title |
---|
Chem. Abstr. 70 (1969) 73580 * |
Houben-Weyl, Methoden der organischen Chemie, 4. Auflage, Bd. IV 1a, 375-376 (1981) * |
Houben-Weyl, Methoden der organischen Chemie, 4. Auflage, Bd. IX, S. 756 (1955) * |
J. Heterocyclic Chem. 16 (1979) 1377-1382 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3321127A1 (de) | 1982-06-17 | 1983-12-22 | Toyama Chemical Co. Ltd., Tokyo | Neues verfahren zur herstellung von 2-(2-aminothiazol-4-yl)-glyoxylsaeure-derivaten oder eines salzes derselben sowie zwischenprodukte derselben und verfahren zur herstellung der zwischenprodukte |
DE3348173C2 (en, 2012) * | 1982-06-17 | 1989-10-05 | Toyama Chemical Co. Ltd., Tokio/Tokyo, Jp |
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