FR2540860B1 - Nouveaux intermediaires pour la production de derives de l'acide 2-(2-aminothiazol-4-yl) glyoxylique ou d'un de ses sels et le procede de production desdits intermediaires - Google Patents

Nouveaux intermediaires pour la production de derives de l'acide 2-(2-aminothiazol-4-yl) glyoxylique ou d'un de ses sels et le procede de production desdits intermediaires

Info

Publication number
FR2540860B1
FR2540860B1 FR848400472A FR8400472A FR2540860B1 FR 2540860 B1 FR2540860 B1 FR 2540860B1 FR 848400472 A FR848400472 A FR 848400472A FR 8400472 A FR8400472 A FR 8400472A FR 2540860 B1 FR2540860 B1 FR 2540860B1
Authority
FR
France
Prior art keywords
intermediates
aminothiazol
salt
producing
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR848400472A
Other languages
English (en)
Other versions
FR2540860A1 (fr
Inventor
Hiroshi Sadaki
Hiroyuki Imaizumi
Kenji Takeda
Takihiro Inaba
Ryuko Takeno
Seishi Morita
Tetsuya Kajita
Isamu Saikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP57103109A external-priority patent/JPS58222076A/ja
Priority claimed from JP57103108A external-priority patent/JPS58222048A/ja
Priority claimed from JP58078201A external-priority patent/JPS59204179A/ja
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Priority to FR848400472A priority Critical patent/FR2540860B1/fr
Publication of FR2540860A1 publication Critical patent/FR2540860A1/fr
Application granted granted Critical
Publication of FR2540860B1 publication Critical patent/FR2540860B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78Separation; Purification; Stabilisation; Use of additives
    • C07C45/79Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78Separation; Purification; Stabilisation; Use of additives
    • C07C45/81Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
    • C07C45/82Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation by distillation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/16Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/40Unsubstituted amino or imino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/46Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/48Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
FR848400472A 1982-06-17 1984-01-13 Nouveaux intermediaires pour la production de derives de l'acide 2-(2-aminothiazol-4-yl) glyoxylique ou d'un de ses sels et le procede de production desdits intermediaires Expired FR2540860B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR848400472A FR2540860B1 (fr) 1982-06-17 1984-01-13 Nouveaux intermediaires pour la production de derives de l'acide 2-(2-aminothiazol-4-yl) glyoxylique ou d'un de ses sels et le procede de production desdits intermediaires

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP57103109A JPS58222076A (ja) 1982-06-17 1982-06-17 2−アミノチアゾ−ル誘導体
JP57103108A JPS58222048A (ja) 1982-06-17 1982-06-17 1―ブロモ―4―クロロブタン―2,3―ジオン
JP58078201A JPS59204179A (ja) 1983-05-06 1983-05-06 2―(2―アミノチアゾール―4―イル)グリオキシル酸誘導体またはその塩の製造法
FR848400472A FR2540860B1 (fr) 1982-06-17 1984-01-13 Nouveaux intermediaires pour la production de derives de l'acide 2-(2-aminothiazol-4-yl) glyoxylique ou d'un de ses sels et le procede de production desdits intermediaires

Publications (2)

Publication Number Publication Date
FR2540860A1 FR2540860A1 (fr) 1984-08-17
FR2540860B1 true FR2540860B1 (fr) 1988-03-25

Family

ID=27302641

Family Applications (3)

Application Number Title Priority Date Filing Date
FR8309863A Expired FR2528839B1 (fr) 1982-06-17 1983-06-15 Nouveau procede de production de derives de l'acide 2-(2-aminothiazol-4-yl) glyoxylique ou d'un de ses sels, les intermediaires necessaires a la synthese de ces derniers, et le procede de production desdits intermediaires
FR848400472A Expired FR2540860B1 (fr) 1982-06-17 1984-01-13 Nouveaux intermediaires pour la production de derives de l'acide 2-(2-aminothiazol-4-yl) glyoxylique ou d'un de ses sels et le procede de production desdits intermediaires
FR8400471A Expired FR2540873B1 (fr) 1982-06-17 1984-01-13 Nouveaux intermediaires pour la production de derives de l'acide 2-(2-aminothiazol-4-yl) glyoxylique ou d'un de ses sels et le procede de production desdits intermediaires

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR8309863A Expired FR2528839B1 (fr) 1982-06-17 1983-06-15 Nouveau procede de production de derives de l'acide 2-(2-aminothiazol-4-yl) glyoxylique ou d'un de ses sels, les intermediaires necessaires a la synthese de ces derniers, et le procede de production desdits intermediaires

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR8400471A Expired FR2540873B1 (fr) 1982-06-17 1984-01-13 Nouveaux intermediaires pour la production de derives de l'acide 2-(2-aminothiazol-4-yl) glyoxylique ou d'un de ses sels et le procede de production desdits intermediaires

Country Status (21)

Country Link
US (2) US4563534A (fr)
KR (1) KR860001027B1 (fr)
AT (1) AT380877B (fr)
AU (1) AU542287B2 (fr)
BE (1) BE897063A (fr)
CA (1) CA1191512A (fr)
DE (2) DE3321127A1 (fr)
DK (3) DK161073C (fr)
ES (3) ES523348A0 (fr)
FI (1) FI85470C (fr)
FR (3) FR2528839B1 (fr)
GB (2) GB2122988B (fr)
IL (1) IL68931A0 (fr)
IT (1) IT1171839B (fr)
MX (1) MX156981A (fr)
NL (1) NL8302151A (fr)
NO (1) NO161114C (fr)
NZ (1) NZ204609A (fr)
PH (3) PH18261A (fr)
PT (1) PT76880B (fr)
SE (3) SE452981B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2122988B (en) 1982-06-17 1986-06-11 Toyama Chemical Co Ltd Process for producing 2-(2-aminothiazol-4-yl) glyoxylic acid derivative; intermediates
AU567990B2 (en) * 1982-06-17 1987-12-10 Toyama Chemical Co. Ltd. Halogenated vicinal diketones
DE3412293A1 (de) * 1984-04-03 1985-10-03 Basf Ag, 6700 Ludwigshafen Thiazolderivate
US5484928A (en) * 1984-04-10 1996-01-16 Biochemie Gesellschaft M.B.H. 2-(2-aminothiazol-4-yl)-2-oxoacetic acid derivatives
EP0407651A3 (en) * 1989-07-10 1991-08-07 J. Uriach & Cia. S.A. Use of 1,3-diisobutyl-8-methylxanthine as a bronchodilator and antiallergy agent
EP3405011A1 (fr) * 2017-05-16 2018-11-21 Arjo Wiggins Fine Papers Limited Électronique de papier en résine, son procédé de fabrication et son application dans des produits manufacturés

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2821555A (en) * 1957-01-07 1958-01-28 Dow Chemical Co 1-bromo-2, 3-butanedione and its 3-oxime derivative
US4191762A (en) * 1974-03-14 1980-03-04 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted amino-2 or 3-cephem-4-carboxylic acid compounds
DE2710902A1 (de) * 1977-03-12 1978-09-21 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4390534A (en) * 1978-12-29 1983-06-28 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
US4308391A (en) * 1979-10-01 1981-12-29 Monsanto Company 2-Amino-4-substituted-thiazolecarboxylic acids and their derivatives
NL8100539A (nl) * 1980-02-12 1981-09-01 Rhone Poulenc Ind Nieuwe thiolesters, de bereiding daarvan en hun gebruik bij syntheses.
CH642957A5 (de) * 1980-02-18 1984-05-15 Lonza Ag Verfahren zur herstellung von (2-aminothiazol-4-yl)-essigsaeure-hydrochlorid.
US4374843A (en) * 1980-10-14 1983-02-22 Pfizer Inc. 2-Guanidino-4-heteroarylthiazoles
GB2122988B (en) 1982-06-17 1986-06-11 Toyama Chemical Co Ltd Process for producing 2-(2-aminothiazol-4-yl) glyoxylic acid derivative; intermediates

Also Published As

Publication number Publication date
DK163816C (da) 1992-09-21
GB2167410A (en) 1986-05-29
ES530213A0 (es) 1985-07-16
FR2540873B1 (fr) 1987-01-02
AU1550083A (en) 1983-12-22
SE8701193L (sv) 1987-03-23
KR860001027B1 (ko) 1986-07-28
FR2540860A1 (fr) 1984-08-17
DK161073B (da) 1991-05-27
AU542287B2 (en) 1985-02-14
FI832152L (fi) 1983-12-18
ATA219783A (de) 1985-12-15
SE8701192L (sv) 1987-03-23
NO161114B (no) 1989-03-28
SE452981B (sv) 1988-01-04
SE8701193D0 (sv) 1987-03-23
DK163582B (da) 1992-03-16
IL68931A0 (en) 1983-10-31
BE897063A (fr) 1983-12-16
FR2528839B1 (fr) 1987-01-02
GB8518464D0 (en) 1985-08-29
DK229090D0 (da) 1990-09-21
DK163816B (da) 1992-04-06
ES8507522A1 (es) 1985-09-01
FR2528839A1 (fr) 1983-12-23
DK229090A (da) 1990-09-21
PH19985A (en) 1986-08-28
CA1191512A (fr) 1985-08-06
FR2540873A1 (fr) 1984-08-17
PH18261A (en) 1985-05-14
SE8701192D0 (sv) 1987-03-23
GB2122988A (en) 1984-01-25
DK163582C (da) 1992-08-10
KR840005117A (ko) 1984-11-03
SE8303465L (sv) 1983-12-18
DK278883D0 (da) 1983-06-16
PT76880A (en) 1983-07-01
NL8302151A (nl) 1984-01-16
ES8502697A1 (es) 1985-01-16
DE3321127A1 (de) 1983-12-22
ES530212A0 (es) 1985-09-01
DK229190A (da) 1990-09-21
DK278883A (da) 1983-12-18
US4667040A (en) 1987-05-19
FI85470B (fi) 1992-01-15
FI832152A0 (fi) 1983-06-14
US4563534A (en) 1986-01-07
DK161073C (da) 1991-11-18
PH20516A (en) 1987-01-26
MX156981A (es) 1988-10-18
NO832178L (no) 1983-12-19
IT1171839B (it) 1987-06-10
ES8506572A1 (es) 1985-07-16
AT380877B (de) 1986-07-25
DE3348173C2 (fr) 1989-10-05
NO161114C (no) 1989-07-05
NZ204609A (en) 1985-12-13
GB8315700D0 (en) 1983-07-13
IT8348504A0 (it) 1983-06-15
DK229190D0 (da) 1990-09-21
SE8303465D0 (sv) 1983-06-16
GB2122988B (en) 1986-06-11
PT76880B (en) 1986-01-27
GB2167410B (en) 1986-11-05
DE3321127C2 (fr) 1988-06-01
ES523348A0 (es) 1985-01-16
FI85470C (fi) 1992-04-27

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Legal Events

Date Code Title Description
ST Notification of lapse