DE2547738C3 - Derivate von Kanamycin A oder B, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel - Google Patents
Derivate von Kanamycin A oder B, Verfahren zu ihrer Herstellung und diese enthaltende ArzneimittelInfo
- Publication number
- DE2547738C3 DE2547738C3 DE2547738A DE2547738A DE2547738C3 DE 2547738 C3 DE2547738 C3 DE 2547738C3 DE 2547738 A DE2547738 A DE 2547738A DE 2547738 A DE2547738 A DE 2547738A DE 2547738 C3 DE2547738 C3 DE 2547738C3
- Authority
- DE
- Germany
- Prior art keywords
- kanamycin
- value
- compounds
- escherichia coli
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
- C07H15/23—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4641274A GB1464401A (en) | 1974-10-26 | 1974-10-26 | Aminoglycosides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE2547738A1 DE2547738A1 (de) | 1976-05-06 |
| DE2547738B2 DE2547738B2 (de) | 1977-12-01 |
| DE2547738C3 true DE2547738C3 (de) | 1978-08-03 |
Family
ID=10441164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2547738A Expired DE2547738C3 (de) | 1974-10-26 | 1975-10-24 | Derivate von Kanamycin A oder B, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
Country Status (28)
| Country | Link |
|---|---|
| JP (1) | JPS5519237B2 (show.php) |
| AR (1) | AR205593A1 (show.php) |
| AT (1) | AT340051B (show.php) |
| BE (1) | BE834864A (show.php) |
| BG (1) | BG24821A3 (show.php) |
| CA (1) | CA1039275A (show.php) |
| CH (1) | CH601339A5 (show.php) |
| CS (1) | CS195712B2 (show.php) |
| DD (1) | DD122522A5 (show.php) |
| DE (1) | DE2547738C3 (show.php) |
| DK (1) | DK147075C (show.php) |
| EG (1) | EG11975A (show.php) |
| ES (1) | ES442051A1 (show.php) |
| FI (1) | FI752951A7 (show.php) |
| FR (1) | FR2289202A1 (show.php) |
| GB (1) | GB1464401A (show.php) |
| HU (1) | HU172060B (show.php) |
| IE (1) | IE42452B1 (show.php) |
| IL (1) | IL48263A (show.php) |
| LU (1) | LU73644A1 (show.php) |
| NL (1) | NL162081C (show.php) |
| NZ (1) | NZ179050A (show.php) |
| PH (1) | PH12782A (show.php) |
| PL (1) | PL99933B1 (show.php) |
| RO (1) | RO72878A (show.php) |
| SE (1) | SE7511945L (show.php) |
| SU (1) | SU617017A3 (show.php) |
| ZA (1) | ZA756326B (show.php) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2860513D1 (en) * | 1977-06-24 | 1981-04-09 | Scherico Ltd | Process for preparing aminoglycoside derivatives, novel derivatives obtained and pharmaceutical compositions containing such derivatives |
| JPS5488241A (en) * | 1977-12-21 | 1979-07-13 | Kyowa Hakko Kogyo Co Ltd | Novel fortimicin a derivative |
| JPS57118475U (show.php) * | 1981-01-14 | 1982-07-22 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH606076A5 (show.php) * | 1973-08-06 | 1978-10-13 | Scherico Ltd |
-
1974
- 1974-10-26 GB GB4641274A patent/GB1464401A/en not_active Expired
-
1975
- 1975-01-01 AR AR260909A patent/AR205593A1/es active
- 1975-10-06 ZA ZA00756326A patent/ZA756326B/xx unknown
- 1975-10-07 IL IL48263A patent/IL48263A/xx unknown
- 1975-10-16 PH PH17665A patent/PH12782A/en unknown
- 1975-10-22 FI FI752951A patent/FI752951A7/fi not_active Application Discontinuation
- 1975-10-22 RO RO7583664A patent/RO72878A/ro unknown
- 1975-10-22 EG EG627/75A patent/EG11975A/xx active
- 1975-10-23 CS CS757161A patent/CS195712B2/cs unknown
- 1975-10-23 AT AT809575A patent/AT340051B/de not_active IP Right Cessation
- 1975-10-24 NL NL7512465.A patent/NL162081C/xx not_active IP Right Cessation
- 1975-10-24 CH CH1380675A patent/CH601339A5/xx not_active IP Right Cessation
- 1975-10-24 LU LU73644A patent/LU73644A1/xx unknown
- 1975-10-24 DK DK481175A patent/DK147075C/da active
- 1975-10-24 JP JP12823775A patent/JPS5519237B2/ja not_active Expired
- 1975-10-24 CA CA238,246A patent/CA1039275A/en not_active Expired
- 1975-10-24 BE BE161248A patent/BE834864A/xx not_active IP Right Cessation
- 1975-10-24 SE SE7511945A patent/SE7511945L/xx unknown
- 1975-10-24 PL PL1975184233A patent/PL99933B1/pl unknown
- 1975-10-24 IE IE2316/75A patent/IE42452B1/en unknown
- 1975-10-24 SU SU752184101A patent/SU617017A3/ru active
- 1975-10-24 FR FR7532662A patent/FR2289202A1/fr active Granted
- 1975-10-24 HU HU75PI00000496A patent/HU172060B/hu unknown
- 1975-10-24 ES ES442051A patent/ES442051A1/es not_active Expired
- 1975-10-24 DD DD189046A patent/DD122522A5/xx unknown
- 1975-10-24 DE DE2547738A patent/DE2547738C3/de not_active Expired
- 1975-10-24 NZ NZ179050A patent/NZ179050A/xx unknown
- 1975-10-24 BG BG031312A patent/BG24821A3/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C3 | Grant after two publication steps (3rd publication) | ||
| 8339 | Ceased/non-payment of the annual fee |