IL48263A - 2-hydroxy-omega-aminoalkyl derivates of aminoglycoside antibiotics,their preparation and pharmaceutical compositions containing them - Google Patents

2-hydroxy-omega-aminoalkyl derivates of aminoglycoside antibiotics,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL48263A
IL48263A IL48263A IL4826375A IL48263A IL 48263 A IL48263 A IL 48263A IL 48263 A IL48263 A IL 48263A IL 4826375 A IL4826375 A IL 4826375A IL 48263 A IL48263 A IL 48263A
Authority
IL
Israel
Prior art keywords
derivates
aminoalkyl
omega
hydroxy
preparation
Prior art date
Application number
IL48263A
Other languages
English (en)
Other versions
IL48263A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL48263A0 publication Critical patent/IL48263A0/xx
Publication of IL48263A publication Critical patent/IL48263A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/23—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL48263A 1974-10-26 1975-10-07 2-hydroxy-omega-aminoalkyl derivates of aminoglycoside antibiotics,their preparation and pharmaceutical compositions containing them IL48263A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4641274A GB1464401A (en) 1974-10-26 1974-10-26 Aminoglycosides

Publications (2)

Publication Number Publication Date
IL48263A0 IL48263A0 (en) 1975-12-31
IL48263A true IL48263A (en) 1978-03-10

Family

ID=10441164

Family Applications (1)

Application Number Title Priority Date Filing Date
IL48263A IL48263A (en) 1974-10-26 1975-10-07 2-hydroxy-omega-aminoalkyl derivates of aminoglycoside antibiotics,their preparation and pharmaceutical compositions containing them

Country Status (28)

Country Link
JP (1) JPS5519237B2 (xx)
AR (1) AR205593A1 (xx)
AT (1) AT340051B (xx)
BE (1) BE834864A (xx)
BG (1) BG24821A3 (xx)
CA (1) CA1039275A (xx)
CH (1) CH601339A5 (xx)
CS (1) CS195712B2 (xx)
DD (1) DD122522A5 (xx)
DE (1) DE2547738C3 (xx)
DK (1) DK147075C (xx)
EG (1) EG11975A (xx)
ES (1) ES442051A1 (xx)
FI (1) FI752951A (xx)
FR (1) FR2289202A1 (xx)
GB (1) GB1464401A (xx)
HU (1) HU172060B (xx)
IE (1) IE42452B1 (xx)
IL (1) IL48263A (xx)
LU (1) LU73644A1 (xx)
NL (1) NL162081C (xx)
NZ (1) NZ179050A (xx)
PH (1) PH12782A (xx)
PL (1) PL99933B1 (xx)
RO (1) RO72878A (xx)
SE (1) SE7511945L (xx)
SU (1) SU617017A3 (xx)
ZA (1) ZA756326B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000473B1 (en) * 1977-06-24 1981-03-11 Scherico Ltd. Process for preparing aminoglycoside derivatives, novel derivatives obtained and pharmaceutical compositions containing such derivatives
JPS5488241A (en) * 1977-12-21 1979-07-13 Kyowa Hakko Kogyo Co Ltd Novel fortimicin a derivative
JPS57118475U (xx) * 1981-01-14 1982-07-22

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606076A5 (xx) * 1973-08-06 1978-10-13 Scherico Ltd

Also Published As

Publication number Publication date
AU8598175A (en) 1976-12-09
GB1464401A (en) 1977-02-16
FR2289202B1 (xx) 1978-11-10
PL99933B1 (pl) 1978-08-31
DK481175A (da) 1976-04-27
ZA756326B (en) 1976-09-29
RO72878A (ro) 1983-07-07
DE2547738A1 (de) 1976-05-06
FR2289202A1 (fr) 1976-05-28
IL48263A0 (en) 1975-12-31
CA1039275A (en) 1978-09-26
NL7512465A (nl) 1976-04-28
BG24821A3 (en) 1978-05-12
EG11975A (en) 1978-06-30
LU73644A1 (xx) 1977-05-31
DD122522A5 (xx) 1976-10-12
AT340051B (de) 1977-11-25
NL162081C (nl) 1980-04-15
CH601339A5 (xx) 1978-07-14
DE2547738C3 (de) 1978-08-03
NL162081B (nl) 1979-11-15
BE834864A (fr) 1976-04-26
IE42452L (en) 1976-04-26
JPS5168543A (xx) 1976-06-14
FI752951A (xx) 1976-04-27
JPS5519237B2 (xx) 1980-05-24
IE42452B1 (en) 1980-08-13
HU172060B (hu) 1978-05-28
PH12782A (en) 1979-08-17
ATA809575A (de) 1977-03-15
DK147075C (da) 1984-11-05
SE7511945L (sv) 1976-04-27
ES442051A1 (es) 1977-04-01
DK147075B (da) 1984-04-02
CS195712B2 (en) 1980-02-29
DE2547738B2 (de) 1977-12-01
SU617017A3 (ru) 1978-07-25
AR205593A1 (es) 1976-05-14
RO72878B (ro) 1983-06-30
NZ179050A (en) 1978-03-06

Similar Documents

Publication Publication Date Title
IL46967A (en) N-pyrrolidyl-, n-piperidyl-,n-pyridyl-and n-pyrroly-polyfluoroalkyl-benzamide derivatives, their preparation and pharmaceutical compositions comprising them
IL47095A0 (en) Thienyl and thietyl ureas,their preparation and pharmaceutical compositions containing them
IL48593A (en) 1-substituted-4-benzylidenepiperidine derivatives, their preparation and pharmaceutical compositions comprising them
IL47360A0 (en) Cephalosporins,their preparation and pharmaceutical compositions containing them
IL46695A (en) Substituted n-(1-benzylpyrrolidinyl-2-alkyl)-benzamides, their preparation and pharmaceutical compositions containing them
IL47529A0 (en) New benzimidazolinone derivatives,their preparation and pharmaceutical compositions containing them
IL48248A0 (en) New antibiotics,their production and pharmaceutical compositions containing them
IL48069A (en) Imidazo-(1,5-a)(1,4)-diazepine derivatives, their preparation and pharmaceutical compositions containing them
IL47877A0 (en) Novel thienothiazine derivatives,their manufacture and pharmaceutical compositions containing them
IL46894A0 (en) New antibiotics,their preparation and pharmaceutical compositions containing them
IL48061A (en) 4a-phenyl-cis-decahydroisoquinoline derivatives, their preparation and pharmaceutical compositions containing them
IL48502A0 (en) Novel benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL47329A (en) Pyridobenzodiazepinones their preparation and pharmaceutical compositions containing them
IL48538A0 (en) Beta-lactam antibiotics,their preparation and pharmaceutical compositions containing them
IL47753A0 (en) Novel triester derivatives of the antibiotic substance sf-837 m1,their preparation and pharmaceutical compositions containing them
IL46631A0 (en) New cephalosporins,their preparation and pharmaceutical compositions containing them
IL47015A (en) Derivatives of phenthylamino-ketones and phenthylamino-dioxolanes,their preparation and pharmaceutical compositions containing them
IL47196A (en) 7-substituted-8-aminomethyl-isoflavone derivatives, their preparation and pharmaceutical compositions containing them
IL47826A (en) 7-aminoalkoxy-chroman and-tetrahydronaphthalene derivatives their preparation and pharmaceutical compositions containing them
IL47892A0 (en) Novel cinnamamide derivatives,their preparation and pharmaceutical compositions containing them
IL48263A (en) 2-hydroxy-omega-aminoalkyl derivates of aminoglycoside antibiotics,their preparation and pharmaceutical compositions containing them
IL47522A0 (en) Ergopeptine derivatives,their preparation and pharmaceutical compositions containing them
IL48526A0 (en) Diaryloxy-imidazolyl-o,n-acetals,their preparation and pharmaceutical compositions containing them
IL47451A (en) Benzhydryloxy-alkylamine derivatives,their preparation and pharmaceutical compositions containing them
IL47654A0 (en) New thieno-pyridine derivatives,their preparation and pharmaceutical compositions containing them