ZA756326B - 2-hydroxy-aminoalkyl-derivatives of aminoglycoside antibiotics - Google Patents
2-hydroxy-aminoalkyl-derivatives of aminoglycoside antibioticsInfo
- Publication number
- ZA756326B ZA756326B ZA00756326A ZA756326A ZA756326B ZA 756326 B ZA756326 B ZA 756326B ZA 00756326 A ZA00756326 A ZA 00756326A ZA 756326 A ZA756326 A ZA 756326A ZA 756326 B ZA756326 B ZA 756326B
- Authority
- ZA
- South Africa
- Prior art keywords
- aminoalkyl
- hydroxy
- derivatives
- aminoglycoside antibiotics
- aminoglycoside
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
- C07H15/23—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL7650576A IL50576A0 (en) | 1975-10-06 | 1976-09-29 | 2-hydroxy-omega-aminoalkyl derivatives of aminoglycosides and their preparation |
AU18235/76A AU491233B2 (en) | 1975-10-06 | 1976-09-29 | 2-hydroxy-w-aminoalkyl-derivatives of aminoglycoside antibiotics |
PH18973A PH14200A (en) | 1975-10-06 | 1976-10-04 | 2-hydroxy-w-aminoalkyl-derivatives of amino glycoside antibiotics |
BE171258A BE846962R (en) | 1974-10-26 | 1976-10-05 | NEW AMINOGLYCOSIDES OF 2-DEOXYSTREPTAMINE, THEIR PREPARATION AND ANTIBACTERIAL COMPOSITION CONTAINING THEM |
LU75939A LU75939A1 (en) | 1974-10-26 | 1976-10-05 | |
DE2644911A DE2644911C3 (en) | 1974-10-26 | 1976-10-05 | Derivatives of kanamycin A or B, processes for their preparation and medicaments containing them |
CA262,724A CA1050975A (en) | 1975-10-06 | 1976-10-05 | 2-HYDROXY-.omega.-AMINOALKYL-DERIVATIVES OF AMINOGLYCOSIDE ANTIBIOTICS |
HU76PI544A HU175520B (en) | 1975-10-06 | 1976-10-05 | Process for producing 2-deoxy-streptamine-amido-glycoside derivatives |
BG7600034371A BG25098A3 (en) | 1975-10-06 | 1976-10-06 | A method of obtaining 2-deoxistreptamine amineglucosides |
FR7630138A FR2326931A2 (en) | 1975-10-06 | 1976-10-06 | (2)-Deoxystreptamine amino-glycoside antibacterials - esp. (1-N)-hydroxy-omega-aminoalkyl kanamycins(OE153077) |
NL7611021.A NL160833C (en) | 1975-10-06 | 1976-10-06 | PROCESS FOR PREPARING ANTI-BACTERIAL KANAMYCIN DERIVATIVES AND PREPARATIONS CONTAINING THEM. |
RO7687926A RO74068A (en) | 1975-10-06 | 1976-10-06 | PROCESS FOR PREPARING 1-N- (S) -2-HYDROXY-6-AMINOHEXYL-KANAMICIN A |
CH7812672A CH608812A5 (en) | 1974-10-26 | 1976-10-06 | |
DD195294A DD126341A6 (en) | 1975-10-06 | 1976-10-15 | |
US05/957,873 US4217446A (en) | 1974-10-26 | 1978-11-06 | ωAmino-2-hydroxyalkyl derivatives of aminoglycoside antibiotics |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4641274A GB1464401A (en) | 1974-10-26 | 1974-10-26 | Aminoglycosides |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA756326B true ZA756326B (en) | 1976-09-29 |
Family
ID=10441164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA00756326A ZA756326B (en) | 1974-10-26 | 1975-10-06 | 2-hydroxy-aminoalkyl-derivatives of aminoglycoside antibiotics |
Country Status (28)
Country | Link |
---|---|
JP (1) | JPS5519237B2 (en) |
AR (1) | AR205593A1 (en) |
AT (1) | AT340051B (en) |
BE (1) | BE834864A (en) |
BG (1) | BG24821A3 (en) |
CA (1) | CA1039275A (en) |
CH (1) | CH601339A5 (en) |
CS (1) | CS195712B2 (en) |
DD (1) | DD122522A5 (en) |
DE (1) | DE2547738C3 (en) |
DK (1) | DK147075C (en) |
EG (1) | EG11975A (en) |
ES (1) | ES442051A1 (en) |
FI (1) | FI752951A (en) |
FR (1) | FR2289202A1 (en) |
GB (1) | GB1464401A (en) |
HU (1) | HU172060B (en) |
IE (1) | IE42452B1 (en) |
IL (1) | IL48263A (en) |
LU (1) | LU73644A1 (en) |
NL (1) | NL162081C (en) |
NZ (1) | NZ179050A (en) |
PH (1) | PH12782A (en) |
PL (1) | PL99933B1 (en) |
RO (1) | RO72878A (en) |
SE (1) | SE7511945L (en) |
SU (1) | SU617017A3 (en) |
ZA (1) | ZA756326B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0000473B1 (en) * | 1977-06-24 | 1981-03-11 | Scherico Ltd. | Process for preparing aminoglycoside derivatives, novel derivatives obtained and pharmaceutical compositions containing such derivatives |
JPS5488241A (en) * | 1977-12-21 | 1979-07-13 | Kyowa Hakko Kogyo Co Ltd | Novel fortimicin a derivative |
JPS57118475U (en) * | 1981-01-14 | 1982-07-22 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH606076A5 (en) * | 1973-08-06 | 1978-10-13 | Scherico Ltd |
-
1974
- 1974-10-26 GB GB4641274A patent/GB1464401A/en not_active Expired
-
1975
- 1975-01-01 AR AR260909A patent/AR205593A1/en active
- 1975-10-06 ZA ZA00756326A patent/ZA756326B/en unknown
- 1975-10-07 IL IL48263A patent/IL48263A/en unknown
- 1975-10-16 PH PH17665A patent/PH12782A/en unknown
- 1975-10-22 RO RO7583664A patent/RO72878A/en unknown
- 1975-10-22 EG EG627/75A patent/EG11975A/en active
- 1975-10-22 FI FI752951A patent/FI752951A/fi not_active Application Discontinuation
- 1975-10-23 CS CS757161A patent/CS195712B2/en unknown
- 1975-10-23 AT AT809575A patent/AT340051B/en not_active IP Right Cessation
- 1975-10-24 CA CA238,246A patent/CA1039275A/en not_active Expired
- 1975-10-24 BE BE161248A patent/BE834864A/en not_active IP Right Cessation
- 1975-10-24 DK DK481175A patent/DK147075C/en active
- 1975-10-24 DD DD189046A patent/DD122522A5/xx unknown
- 1975-10-24 SE SE7511945A patent/SE7511945L/en unknown
- 1975-10-24 HU HU75PI00000496A patent/HU172060B/en unknown
- 1975-10-24 ES ES442051A patent/ES442051A1/en not_active Expired
- 1975-10-24 IE IE2316/75A patent/IE42452B1/en unknown
- 1975-10-24 FR FR7532662A patent/FR2289202A1/en active Granted
- 1975-10-24 SU SU752184101A patent/SU617017A3/en active
- 1975-10-24 NZ NZ179050A patent/NZ179050A/en unknown
- 1975-10-24 LU LU73644A patent/LU73644A1/xx unknown
- 1975-10-24 CH CH1380675A patent/CH601339A5/xx not_active IP Right Cessation
- 1975-10-24 PL PL1975184233A patent/PL99933B1/en unknown
- 1975-10-24 DE DE2547738A patent/DE2547738C3/en not_active Expired
- 1975-10-24 BG BG7500031312A patent/BG24821A3/en unknown
- 1975-10-24 NL NL7512465.A patent/NL162081C/en not_active IP Right Cessation
- 1975-10-24 JP JP12823775A patent/JPS5519237B2/ja not_active Expired
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