DD289529A5 - Verfahren zur herstellung heterozyklischer verbindungen - Google Patents

Verfahren zur herstellung heterozyklischer verbindungen Download PDF

Info

Publication number
DD289529A5
DD289529A5 DD88318868A DD31886888A DD289529A5 DD 289529 A5 DD289529 A5 DD 289529A5 DD 88318868 A DD88318868 A DD 88318868A DD 31886888 A DD31886888 A DD 31886888A DD 289529 A5 DD289529 A5 DD 289529A5
Authority
DD
German Democratic Republic
Prior art keywords
carbamate
group
formula
imidazo
methyl
Prior art date
Application number
DD88318868A
Other languages
German (de)
English (en)
Inventor
Simon T Hodgson
Original Assignee
��������@��������@����������@���k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ��������@��������@����������@���k�� filed Critical ��������@��������@����������@���k��
Publication of DD289529A5 publication Critical patent/DD289529A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DD88318868A 1987-08-15 1988-08-12 Verfahren zur herstellung heterozyklischer verbindungen DD289529A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878719368A GB8719368D0 (en) 1987-08-15 1987-08-15 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
DD289529A5 true DD289529A5 (de) 1991-05-02

Family

ID=10622364

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88318868A DD289529A5 (de) 1987-08-15 1988-08-12 Verfahren zur herstellung heterozyklischer verbindungen

Country Status (28)

Country Link
US (5) US5091531A (fr)
EP (1) EP0305093B1 (fr)
JP (1) JPS6468375A (fr)
KR (1) KR890003764A (fr)
CN (2) CN1031532A (fr)
AP (1) AP89A (fr)
AT (1) ATE103919T1 (fr)
AU (1) AU613392B2 (fr)
CA (1) CA1336432C (fr)
DD (1) DD289529A5 (fr)
DE (1) DE3888897T2 (fr)
DK (1) DK168954B1 (fr)
ES (1) ES2063039T3 (fr)
FI (1) FI89600C (fr)
GB (1) GB8719368D0 (fr)
HU (1) HU204052B (fr)
IL (1) IL87435A (fr)
MC (1) MC1969A1 (fr)
MX (1) MX12655A (fr)
MY (1) MY103602A (fr)
NO (1) NO168305C (fr)
NZ (1) NZ225808A (fr)
PH (1) PH25741A (fr)
PL (3) PL160044B1 (fr)
PT (1) PT88260B (fr)
RU (3) RU1769759C (fr)
YU (3) YU47200B (fr)
ZA (1) ZA885996B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds
PH27291A (en) * 1989-01-31 1993-05-04 Takeda Chemical Industries Ltd Imidazolpyrimidazines their production and use
EP0440119A1 (fr) * 1990-01-31 1991-08-07 Takeda Chemical Industries, Ltd. Composés de imidazopyridazine, leur préparation et utilisation
EP0444549B1 (fr) * 1990-03-01 1995-01-25 Takeda Chemical Industries, Ltd. Imidazopyridazines, leur préparation et leur application
ATE256128T1 (de) * 1998-10-21 2003-12-15 Takeda Chemical Industries Ltd Kondensierte pyridazinderivate, verfahren zu ihrer herstellung und ihre anwendung
CA2413802A1 (fr) 2000-06-30 2002-01-10 Mark R. Schmitt Triazolopyrimidines substitues comme agents anticancereux
JP3767352B2 (ja) 2000-09-18 2006-04-19 トヨタ自動車株式会社 内燃機関の制御装置
AU2002251266A1 (en) * 2001-04-10 2002-10-28 Merck Sharp And Dohme Limited Inhibitors of akt activity
CL2007002261A1 (es) * 2006-08-04 2008-05-02 Takeda Pharmaceutical Compuestos derivados de imidazo[1,2-b]piridazina, inhibidores de quinasa; composicion farmaceutica; y uso en el tratamiento o prevencion del cancer.
BRPI0718029A2 (pt) * 2006-11-06 2013-11-26 Supergen Inc Derivados de imidazo(1,2-b)piridazina e pirazolo(1,5-a)pirimidina e seu uso como inibidores da proteína cinase
US8431608B2 (en) 2007-08-17 2013-04-30 Icagen Inc. Heterocycles as potassium channel modulators
AU2008289101A1 (en) * 2007-08-17 2009-02-26 Icagen, Inc. Heterocycles as potassium channel modulators
KR20100128305A (ko) * 2008-02-28 2010-12-07 노파르티스 아게 C-met 티로신 키나제 매개 질환의 치료를 위한 이미다조[1,2-b]피리다진 유도체
JPWO2009128520A1 (ja) * 2008-04-18 2011-08-04 塩野義製薬株式会社 Pi3k阻害活性を有する複素環化合物
UY32049A (es) * 2008-08-14 2010-03-26 Takeda Pharmaceutical Inhibidores de cmet
TW201437211A (zh) * 2013-03-01 2014-10-01 Bayer Pharma AG 經取代咪唑并嗒□

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB305093A (en) * 1928-01-30 1929-07-25 British Continental Motors Ltd Improvements relating to induction passages of sleeve-valve internal combustion engines
US3615639A (en) * 1967-10-23 1971-10-26 Eastman Kodak Co Direct positive silver halide emulsions containing dyes as electron acceptors and spectral sensitizers
US3809691A (en) * 1967-10-23 1974-05-07 Eastman Kodak Co Novel cyanine dyes with fused imidazolo nuclei
DE2043811A1 (en) * 1970-09-03 1972-03-09 E.I. du Pont de Nemours and Co., Wilmington, Del. (V.StA.) Fungicidal and acaricidal alkyl 2-benzimi- - dazole carbomate derivs
US3725407A (en) * 1971-04-08 1973-04-03 American Cyanamid Co 6-substituted amino-3-nitroimidazo(1,2-b)pyridazines and methods of preparing the same
FR2315507A1 (fr) * 1975-06-26 1977-01-21 Roussel Uclaf Imidazo /1,2-b/ pyridazines substituees, procede de preparation et compositions pesticides les renfermant
US4105767A (en) * 1977-03-28 1978-08-08 Merck & Co., Inc. Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group
US4166851A (en) * 1977-05-16 1979-09-04 Merck & Co., Inc. Certain imidazo(1,2a)pyridine derivatives
US4154835A (en) * 1977-10-12 1979-05-15 Merck & Co., Inc. Anthelmintic imidazo [1,2-a] pyridines
US4330543A (en) * 1978-12-14 1982-05-18 Merck & Co., Inc. Imidazoazines and imidazodiazines
US4221796A (en) * 1979-09-19 1980-09-09 E. R. Squibb & Sons, Inc. Substituted imidazolo-pyridines and method
DE3131365A1 (de) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
JPS58126887A (ja) * 1981-09-26 1983-07-28 Takeda Chem Ind Ltd 新規7−デアザプリン誘導体
US4460773A (en) * 1982-02-05 1984-07-17 Lion Corporation 1-Phenyl-1H-pyrazolo [3,4-b]pyrazine derivatives and process for preparing same
US4464372A (en) * 1982-08-16 1984-08-07 Schering Corporation Imidazo[1,2-b]pyridazines
IL69417A (en) * 1982-08-27 1987-12-20 Roussel Uclaf 2-acyl imidazo(1,2-a)pyrimidines,their preparation and pharmaceutical compositions containing them
US4654347A (en) * 1983-06-23 1987-03-31 American Cyanamid Company Aryl and heteroaryl[[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]methanones
DE3401911A1 (de) * 1984-01-20 1985-08-01 A. Nattermann & Cie GmbH, 5000 Köln Substituierte 4,5-dihydro-6-vinyl-3(2h)-pyridazinone und 6-vinyl-3(2h)-pyridazinone sowie verfahren zu ihrer herstellung
DE3423092A1 (de) * 1984-06-22 1986-01-02 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 8-alkylthio-2-piperazino-pyrimido(5,4-d) pyrimidine, ihre herstellung und diese verbindungen enthaltende arzneimittel
US4569934A (en) * 1984-10-09 1986-02-11 American Cyanamid Company Imidazo[1,2-b]pyridazines
DE3446812A1 (de) * 1984-12-21 1986-06-26 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3446778A1 (de) * 1984-12-21 1986-07-03 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3527036A1 (de) * 1985-07-27 1987-02-05 Merck Patent Gmbh 6-arylalkenylpyridazinone
DE3542661A1 (de) * 1985-12-03 1987-06-04 Bayer Ag Imidazopyridazinalkensaeureamide, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung
WO1989001478A1 (fr) * 1987-08-07 1989-02-23 The Australian National University IMIDAZO[1,2-b]PYRIDAZINES AVEC SUBSTITUANTS ARYLOXY ET ARALKYLTHIO
WO1989001333A1 (fr) * 1987-08-07 1989-02-23 The Australian National University IMIDAZO[1,2-b]PYRIDAZINES
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds

Also Published As

Publication number Publication date
FI883758A (fi) 1989-02-16
AP89A (en) 1990-06-14
NO883613L (no) 1989-02-16
JPS6468375A (en) 1989-03-14
NO168305B (no) 1991-10-28
YU202889A (en) 1990-04-30
YU202789A (en) 1990-04-30
US5538970A (en) 1996-07-23
CN1031532A (zh) 1989-03-08
PL274216A1 (en) 1989-05-02
PL160045B1 (en) 1993-02-26
EP0305093A1 (fr) 1989-03-01
ZA885996B (en) 1990-04-25
MC1969A1 (fr) 1989-09-29
CA1336432C (fr) 1995-07-25
RU2017741C1 (ru) 1994-08-15
EP0305093B1 (fr) 1994-04-06
US5447956A (en) 1995-09-05
MY103602A (en) 1993-08-28
PH25741A (en) 1991-10-18
YU47130B (sh) 1994-12-28
AP8800098A0 (en) 1988-08-01
RU1769759C (ru) 1992-10-15
NO168305C (no) 1992-02-05
KR890003764A (ko) 1989-04-17
FI89600C (fi) 1993-10-25
DK451588D0 (da) 1988-08-12
US5380759A (en) 1995-01-10
GB8719368D0 (en) 1987-09-23
FI883758A0 (fi) 1988-08-12
CN1085901A (zh) 1994-04-27
YU47212B (sh) 1995-01-31
PL160044B1 (pl) 1993-02-26
HUT50473A (en) 1990-02-28
PL159008B1 (pl) 1992-11-30
AU613392B2 (en) 1991-08-01
IL87435A (en) 1993-01-31
RU1836372C (ru) 1993-08-23
HU204052B (en) 1991-11-28
AU2097988A (en) 1989-02-16
DK168954B1 (da) 1994-07-18
NZ225808A (en) 1991-07-26
MX12655A (es) 1993-10-01
ATE103919T1 (de) 1994-04-15
YU47200B (sh) 1995-01-31
FI89600B (fi) 1993-07-15
PT88260A (pt) 1989-09-14
ES2063039T3 (es) 1995-01-01
DE3888897D1 (de) 1994-05-11
DE3888897T2 (de) 1994-10-20
US5091531A (en) 1992-02-25
DK451588A (da) 1989-02-16
US5371219A (en) 1994-12-06
NO883613D0 (no) 1988-08-12
PT88260B (pt) 1995-03-01
IL87435A0 (en) 1989-01-31
YU156988A (en) 1990-04-30

Similar Documents

Publication Publication Date Title
DE69836332T2 (de) Benzyliden-1,3-dihydro-indol-2-on-derivate als inhibitoren von rezeptor tyrosin kinasen, insbesondere von raf kinasen
EP0682027B1 (fr) Dérivés de la pyrrolopyrimidine avec une activité anti-proliférative
DE2265617C3 (de) 5-Chlor-2- [3-(aminomethyl)-5-methyl-4H-1.2.4-triazol-4-yl]-benzophenone
DE69930120T2 (de) Annellierte azepinone als inhibitoren cyclin-abhängiger kinasen
DD289529A5 (de) Verfahren zur herstellung heterozyklischer verbindungen
EP0005205A1 (fr) 5.6-Diméthylpyrrolo(2,3-d)pyrimidines substituées, leur procédé de préparation et médicamentsles contenant
DE4034687A1 (de) Neue isoindolderivate und ihre salze, verfahren zu deren herstellung und antitumor-mittel mit einem gehalt derselben
US4992442A (en) Pyrrolo(3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same
EP0039519A1 (fr) Thiénotricycles substitués, procédé de préparation et médicaments les contenant
DD236928A5 (de) Verfahren zur herstellung neuer 1,2,4-triazolo-carbamate
DE2233682A1 (de) 2- eckige klammer auf 3-(subst. aminomethyl)-4-h-1,2,4-triazol-4-yl eckige klammer zu -benzophenone, ein verfahren zu ihrer herstellung sowie diese enthaltende arzneimittel
EP0180833B1 (fr) Dérivés de la 4-oxopyrido[2,3-d]pyrimidine, procédé pour leur préparation et médicaments les contenant
CH636876A5 (de) Imidazo- und pyrimido(2,1-b)chinazoline, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
US5114944A (en) 2-phenylpyrazolo[1,5-a]pyrimidine-3-acetic acid derivatives exhibiting therapeutic effects
EP0997463A1 (fr) Derives de naphthyridine
DE2221808C2 (de) Hydrazinopyridazin-Derivate, deren Säureadditionssalze, Verfahren zu deren Herstellung und Heilmittel
DE60010311T2 (de) Triazolpurin-derivate, medikamentzusammensetzungen, die diese enthalten und mittel, die affinität zum adenosin a3 rezeptor zeigen
DD201594A5 (de) Verfahren zur herstellung von neuen polyazaheterocyclischen verbindungen
AU640135B2 (en) Hetero polycyclic biocidal compounds and their use in medicine
DE2240043A1 (de) (phenyl-tolyl)-1,2,4-triazole und verfahren zu ihrer herstellung
EP0024582A1 (fr) Benzodiazépinones, procédé pour leur préparation et médicaments les contenant
EP0094668B1 (fr) Dérivés de pyrrolo-(3,4-d)(2)benzazépine
DE2257627A1 (de) 4-(2-benzoylphenyl)-2,4-dihydro-5eckige klammer auf (alkylamino)-alkyl eckige klammer zu- 3h-1,2,4-triazol-3-one, deren saeureanlagerungssalze und verfahren zur herstellung dieser verbindungen
DE2435041B2 (de) 8-substituierte 6-aryl-4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung, ihre verwendung in arzneimitteln und diese enthaltende pharmazeutische praeparate
JPS6125035B2 (fr)

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee