DE3888897D1 - Imidazo[1,2-b]pyridazinderivate. - Google Patents

Imidazo[1,2-b]pyridazinderivate.

Info

Publication number
DE3888897D1
DE3888897D1 DE88307513T DE3888897T DE3888897D1 DE 3888897 D1 DE3888897 D1 DE 3888897D1 DE 88307513 T DE88307513 T DE 88307513T DE 3888897 T DE3888897 T DE 3888897T DE 3888897 D1 DE3888897 D1 DE 3888897D1
Authority
DE
Germany
Prior art keywords
imidazo
pyridazine derivatives
pyridazine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88307513T
Other languages
English (en)
Other versions
DE3888897T2 (de
Inventor
Simon Teanby Hodgson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Application granted granted Critical
Publication of DE3888897D1 publication Critical patent/DE3888897D1/de
Publication of DE3888897T2 publication Critical patent/DE3888897T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE3888897T 1987-08-15 1988-08-12 Imidazo[1,2-b]pyridazinderivate. Expired - Fee Related DE3888897T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878719368A GB8719368D0 (en) 1987-08-15 1987-08-15 Heterocyclic compounds

Publications (2)

Publication Number Publication Date
DE3888897D1 true DE3888897D1 (de) 1994-05-11
DE3888897T2 DE3888897T2 (de) 1994-10-20

Family

ID=10622364

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3888897T Expired - Fee Related DE3888897T2 (de) 1987-08-15 1988-08-12 Imidazo[1,2-b]pyridazinderivate.

Country Status (28)

Country Link
US (5) US5091531A (de)
EP (1) EP0305093B1 (de)
JP (1) JPS6468375A (de)
KR (1) KR890003764A (de)
CN (2) CN1031532A (de)
AP (1) AP89A (de)
AT (1) ATE103919T1 (de)
AU (1) AU613392B2 (de)
CA (1) CA1336432C (de)
DD (1) DD289529A5 (de)
DE (1) DE3888897T2 (de)
DK (1) DK168954B1 (de)
ES (1) ES2063039T3 (de)
FI (1) FI89600C (de)
GB (1) GB8719368D0 (de)
HU (1) HU204052B (de)
IL (1) IL87435A (de)
MC (1) MC1969A1 (de)
MX (1) MX12655A (de)
MY (1) MY103602A (de)
NO (1) NO168305C (de)
NZ (1) NZ225808A (de)
PH (1) PH25741A (de)
PL (3) PL159008B1 (de)
PT (1) PT88260B (de)
RU (3) RU1769759C (de)
YU (3) YU47200B (de)
ZA (1) ZA885996B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds
PH27291A (en) * 1989-01-31 1993-05-04 Takeda Chemical Industries Ltd Imidazolpyrimidazines their production and use
EP0440119A1 (de) * 1990-01-31 1991-08-07 Takeda Chemical Industries, Ltd. Imidazopyridazinverbindungen, ihre Herstellung und Verwendung
ATE117690T1 (de) * 1990-03-01 1995-02-15 Takeda Chemical Industries Ltd Imidazopyridazine, ihre herstellung und verwendung.
US6627630B1 (en) * 1998-10-21 2003-09-30 Takeda Chemical Industries, Ltd. Condensed pyridazine derivatives, their production and use
NZ523807A (en) 2000-06-30 2004-09-24 Wyeth Corp Substituted-triazolopyrimidines as anticancer agents
JP3767352B2 (ja) 2000-09-18 2006-04-19 トヨタ自動車株式会社 内燃機関の制御装置
AU2002251266A1 (en) * 2001-04-10 2002-10-28 Merck Sharp And Dohme Limited Inhibitors of akt activity
JP5238697B2 (ja) * 2006-08-04 2013-07-17 武田薬品工業株式会社 縮合複素環誘導体およびその用途
EP2086979B1 (de) * 2006-11-06 2015-06-03 Tolero Pharmaceuticals, Inc. Imidazo[1,2-b]pyridazin- und pyrazolo[1,5-a]pyrimidinderivate und ihre verwendung als proteinkinasehemmer
AU2008289101A1 (en) * 2007-08-17 2009-02-26 Icagen, Inc. Heterocycles as potassium channel modulators
US8431608B2 (en) 2007-08-17 2013-04-30 Icagen Inc. Heterocycles as potassium channel modulators
BRPI0908504A2 (pt) * 2008-02-28 2015-08-11 Novatis Ag Compostos derivados de 3-metil-imidazo[1,2-b]piridazina, uso dos mesmos e composição farmacêutica
EP2444403A1 (de) * 2008-04-18 2012-04-25 Shionogi Co., Ltd. Heterocyclische Verbindung mit hemmender Wirkung gegenüber PI3K
UY32049A (es) * 2008-08-14 2010-03-26 Takeda Pharmaceutical Inhibidores de cmet
TW201437211A (zh) * 2013-03-01 2014-10-01 Bayer Pharma AG 經取代咪唑并嗒□

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB305093A (en) * 1928-01-30 1929-07-25 British Continental Motors Ltd Improvements relating to induction passages of sleeve-valve internal combustion engines
US3615639A (en) * 1967-10-23 1971-10-26 Eastman Kodak Co Direct positive silver halide emulsions containing dyes as electron acceptors and spectral sensitizers
US3809691A (en) * 1967-10-23 1974-05-07 Eastman Kodak Co Novel cyanine dyes with fused imidazolo nuclei
DE2043811A1 (en) * 1970-09-03 1972-03-09 E.I. du Pont de Nemours and Co., Wilmington, Del. (V.StA.) Fungicidal and acaricidal alkyl 2-benzimi- - dazole carbomate derivs
US3725407A (en) * 1971-04-08 1973-04-03 American Cyanamid Co 6-substituted amino-3-nitroimidazo(1,2-b)pyridazines and methods of preparing the same
FR2315507A1 (fr) * 1975-06-26 1977-01-21 Roussel Uclaf Imidazo /1,2-b/ pyridazines substituees, procede de preparation et compositions pesticides les renfermant
US4105767A (en) * 1977-03-28 1978-08-08 Merck & Co., Inc. Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group
US4166851A (en) * 1977-05-16 1979-09-04 Merck & Co., Inc. Certain imidazo(1,2a)pyridine derivatives
US4154835A (en) * 1977-10-12 1979-05-15 Merck & Co., Inc. Anthelmintic imidazo [1,2-a] pyridines
US4330543A (en) * 1978-12-14 1982-05-18 Merck & Co., Inc. Imidazoazines and imidazodiazines
US4221796A (en) * 1979-09-19 1980-09-09 E. R. Squibb & Sons, Inc. Substituted imidazolo-pyridines and method
DE3131365A1 (de) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
JPS58126887A (ja) * 1981-09-26 1983-07-28 Takeda Chem Ind Ltd 新規７−デアザプリン誘導体
US4460773A (en) * 1982-02-05 1984-07-17 Lion Corporation 1-Phenyl-1H-pyrazolo [3,4-b]pyrazine derivatives and process for preparing same
US4464372A (en) * 1982-08-16 1984-08-07 Schering Corporation Imidazo[1,2-b]pyridazines
IL69417A (en) * 1982-08-27 1987-12-20 Roussel Uclaf 2-acyl imidazo(1,2-a)pyrimidines,their preparation and pharmaceutical compositions containing them
US4654347A (en) * 1983-06-23 1987-03-31 American Cyanamid Company Aryl and heteroaryl[[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]methanones
DE3401911A1 (de) * 1984-01-20 1985-08-01 A. Nattermann & Cie GmbH, 5000 Köln Substituierte 4,5-dihydro-6-vinyl-3(2h)-pyridazinone und 6-vinyl-3(2h)-pyridazinone sowie verfahren zu ihrer herstellung
DE3423092A1 (de) * 1984-06-22 1986-01-02 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 8-alkylthio-2-piperazino-pyrimido(5,4-d) pyrimidine, ihre herstellung und diese verbindungen enthaltende arzneimittel
US4569934A (en) * 1984-10-09 1986-02-11 American Cyanamid Company Imidazo[1,2-b]pyridazines
DE3446778A1 (de) * 1984-12-21 1986-07-03 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3446812A1 (de) * 1984-12-21 1986-06-26 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3527036A1 (de) * 1985-07-27 1987-02-05 Merck Patent Gmbh 6-arylalkenylpyridazinone
DE3542661A1 (de) * 1985-12-03 1987-06-04 Bayer Ag Imidazopyridazinalkensaeureamide, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung
WO1989001478A1 (en) * 1987-08-07 1989-02-23 The Australian National University ARYLOXY- AND ARALKYLTHIO-IMIDAZO[1,2-b]PYRIDAZINES
WO1989001333A1 (en) * 1987-08-07 1989-02-23 The Australian National University IMIDAZO[1,2-b]PYRIDAZINES
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds

Also Published As

Publication number Publication date
YU202789A (en) 1990-04-30
IL87435A0 (en) 1989-01-31
RU1836372C (ru) 1993-08-23
HUT50473A (en) 1990-02-28
DE3888897T2 (de) 1994-10-20
US5447956A (en) 1995-09-05
AP89A (en) 1990-06-14
DK168954B1 (da) 1994-07-18
EP0305093B1 (de) 1994-04-06
HU204052B (en) 1991-11-28
MC1969A1 (fr) 1989-09-29
CN1031532A (zh) 1989-03-08
PL160044B1 (pl) 1993-02-26
MY103602A (en) 1993-08-28
NO883613L (no) 1989-02-16
CA1336432C (en) 1995-07-25
GB8719368D0 (en) 1987-09-23
YU202889A (en) 1990-04-30
DD289529A5 (de) 1991-05-02
PT88260A (pt) 1989-09-14
YU156988A (en) 1990-04-30
FI883758A0 (fi) 1988-08-12
AU613392B2 (en) 1991-08-01
ZA885996B (en) 1990-04-25
IL87435A (en) 1993-01-31
PL274216A1 (en) 1989-05-02
JPS6468375A (en) 1989-03-14
US5380759A (en) 1995-01-10
PH25741A (en) 1991-10-18
FI89600C (fi) 1993-10-25
FI883758A (fi) 1989-02-16
US5371219A (en) 1994-12-06
NZ225808A (en) 1991-07-26
DK451588D0 (da) 1988-08-12
PL159008B1 (pl) 1992-11-30
AP8800098A0 (en) 1988-08-01
FI89600B (fi) 1993-07-15
AU2097988A (en) 1989-02-16
US5538970A (en) 1996-07-23
YU47130B (sh) 1994-12-28
RU2017741C1 (ru) 1994-08-15
NO168305C (no) 1992-02-05
NO168305B (no) 1991-10-28
PT88260B (pt) 1995-03-01
RU1769759C (ru) 1992-10-15
EP0305093A1 (de) 1989-03-01
PL160045B1 (en) 1993-02-26
YU47200B (sh) 1995-01-31
KR890003764A (ko) 1989-04-17
CN1085901A (zh) 1994-04-27
YU47212B (sh) 1995-01-31
ES2063039T3 (es) 1995-01-01
NO883613D0 (no) 1988-08-12
MX12655A (es) 1993-10-01
ATE103919T1 (de) 1994-04-15
US5091531A (en) 1992-02-25
DK451588A (da) 1989-02-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee