DK232387A - Diastereoisomere tetrahydropyrido (2,3-d) pyrimi- din derivativer - Google Patents

Diastereoisomere tetrahydropyrido (2,3-d) pyrimi- din derivativer

Info

Publication number
DK232387A
DK232387A DK232387A DK232387A DK232387A DK 232387 A DK232387 A DK 232387A DK 232387 A DK232387 A DK 232387A DK 232387 A DK232387 A DK 232387A DK 232387 A DK232387 A DK 232387A
Authority
DK
Denmark
Prior art keywords
tetrahydropyrido
diastereoisomer
pyrimidine derivatives
pyrimidine
derivatives
Prior art date
Application number
DK232387A
Other languages
English (en)
Other versions
DK232387D0 (da
DK170023B1 (da
Inventor
Edward C Taylor
George Peter Beardsley
Chuan Shih
Stephen R Fletcher
Original Assignee
Univ Princeton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Princeton filed Critical Univ Princeton
Publication of DK232387D0 publication Critical patent/DK232387D0/da
Publication of DK232387A publication Critical patent/DK232387A/da
Application granted granted Critical
Publication of DK170023B1 publication Critical patent/DK170023B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK232387A 1986-06-06 1987-05-06 Diastereoisomere tetrahydropyrido[2,3-d]pyrimidin-derivater samt fremgangsmåde til adskillelse af disse diastereoisomere forbindelser DK170023B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87153986A 1986-06-06 1986-06-06
US87153986 1986-06-06

Publications (3)

Publication Number Publication Date
DK232387D0 DK232387D0 (da) 1987-05-06
DK232387A true DK232387A (da) 1987-12-07
DK170023B1 DK170023B1 (da) 1995-05-01

Family

ID=25357673

Family Applications (1)

Application Number Title Priority Date Filing Date
DK232387A DK170023B1 (da) 1986-06-06 1987-05-06 Diastereoisomere tetrahydropyrido[2,3-d]pyrimidin-derivater samt fremgangsmåde til adskillelse af disse diastereoisomere forbindelser

Country Status (15)

Country Link
EP (1) EP0248573A3 (da)
JP (1) JPH07116190B2 (da)
KR (1) KR950004894B1 (da)
CN (1) CN1019391B (da)
AU (1) AU592182B2 (da)
CA (1) CA1301155C (da)
DK (1) DK170023B1 (da)
EG (1) EG19551A (da)
ES (1) ES2003828A6 (da)
GR (1) GR870783B (da)
NZ (1) NZ219971A (da)
PH (1) PH25509A (da)
PT (1) PT84990B (da)
SU (1) SU1627087A3 (da)
ZA (1) ZA873083B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE60038B1 (en) * 1986-06-30 1994-05-18 Univ Princeton 4(3H)-oxo-5, 6, 7, 8-tetrahydropyrido-[2, 3-d]pyrimidine derivatives
GB8625019D0 (en) * 1986-10-18 1986-11-19 Wellcome Found Compounds
US4895946A (en) * 1987-10-26 1990-01-23 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
US4889859A (en) * 1988-02-05 1989-12-26 The Trustees Of Princeton University Pyrido[2,3-d]pyrimidine derivatives
JP2830008B2 (ja) * 1988-04-01 1998-12-02 武田薬品工業株式会社 縮合ピリミジン誘導体
US5223620A (en) * 1988-04-01 1993-06-29 Takeda Chemical Industries, Ltd. Pyrido[2,3-d]pyrimidine compounds useful as intermediates
DK172753B1 (da) * 1988-05-25 1999-06-28 Lilly Co Eli N-(5,6,7,8-tetrahydropyrido[2,3--d]pyrimidin-6-yl-alkanoyl)-glutaminsyrederivater, deres anvendelse, farmaceutiske præparat
US5008391A (en) * 1989-07-07 1991-04-16 Eli Lilly And Company Enantioselective synthesis of antifolates
US5066828A (en) * 1990-04-12 1991-11-19 Merrell Dow Pharmaceuticals Inc. Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
KR20010040836A (ko) * 1998-02-11 2001-05-15 피터 지. 스트링거 항엽산제의 제조 방법 및 유용한 중간체
CN110749692B (zh) * 2019-10-15 2022-03-18 扬子江药业集团有限公司 L-谷氨酸二乙酯盐酸盐及其光学异构体的分离检测方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA861235B (en) * 1985-03-08 1986-10-29 Univ Princeton Pyrido(2,3-d)pyrimidine derivatives

Also Published As

Publication number Publication date
CA1301155C (en) 1992-05-19
CN87104103A (zh) 1987-12-30
PT84990B (pt) 1990-03-08
CN1019391B (zh) 1992-12-09
DK232387D0 (da) 1987-05-06
DK170023B1 (da) 1995-05-01
NZ219971A (en) 1989-08-29
PT84990A (en) 1987-07-01
ES2003828A6 (es) 1988-11-16
EG19551A (en) 1996-02-29
GR870783B (en) 1987-09-25
AU7273187A (en) 1987-12-10
AU592182B2 (en) 1990-01-04
SU1627087A3 (ru) 1991-02-07
JPS6339878A (ja) 1988-02-20
PH25509A (en) 1991-07-24
EP0248573A2 (en) 1987-12-09
KR880000431A (ko) 1988-03-25
ZA873083B (en) 1987-10-26
EP0248573A3 (en) 1989-06-14
JPH07116190B2 (ja) 1995-12-13
KR950004894B1 (ko) 1995-05-15

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Legal Events

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B1 Patent granted (law 1993)
PBP Patent lapsed

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