DK307387A - 4(3h)-oxo-5,6,7,8-tetrahydropyrido-(2,3-d)pyrimidinderivater - Google Patents

4(3h)-oxo-5,6,7,8-tetrahydropyrido-(2,3-d)pyrimidinderivater

Info

Publication number
DK307387A
DK307387A DK307387A DK307387A DK307387A DK 307387 A DK307387 A DK 307387A DK 307387 A DK307387 A DK 307387A DK 307387 A DK307387 A DK 307387A DK 307387 A DK307387 A DK 307387A
Authority
DK
Denmark
Prior art keywords
pyrido
tetrahydro
oxo
pyrimidine derivatives
pyrimidine
Prior art date
Application number
DK307387A
Other languages
English (en)
Other versions
DK172896B1 (da
DK307387D0 (da
Inventor
Edward C Taylor
George Peter Beardsley
James M Hamby
Chuan Shih
Original Assignee
Univ Princeton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/040,330 external-priority patent/US4831037A/en
Application filed by Univ Princeton filed Critical Univ Princeton
Publication of DK307387D0 publication Critical patent/DK307387D0/da
Publication of DK307387A publication Critical patent/DK307387A/da
Application granted granted Critical
Publication of DK172896B1 publication Critical patent/DK172896B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK198703073A 1986-06-30 1987-06-17 4(3H)-oxo-5,6,7,8-tetrahydropyrido-(2,3-d)pyrimidinderivater, farmaceutiske præparater indeholdende dem samt fremgangsmåder DK172896B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US87993586A 1986-06-30 1986-06-30
US87993586 1986-06-30
US07/040,330 US4831037A (en) 1987-04-20 1987-04-20 4 (3H)-oxo-5,6,7,8-tetrahydropyrido-(2,3-d)pyrimidine derivatives
US4033087 1987-04-20

Publications (3)

Publication Number Publication Date
DK307387D0 DK307387D0 (da) 1987-06-17
DK307387A true DK307387A (da) 1987-12-31
DK172896B1 DK172896B1 (da) 1999-09-20

Family

ID=26716970

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198703073A DK172896B1 (da) 1986-06-30 1987-06-17 4(3H)-oxo-5,6,7,8-tetrahydropyrido-(2,3-d)pyrimidinderivater, farmaceutiske præparater indeholdende dem samt fremgangsmåder

Country Status (17)

Country Link
EP (1) EP0255228B1 (da)
JP (1) JPH07116189B2 (da)
KR (1) KR950001017B1 (da)
CN (1) CN1014895B (da)
AU (1) AU594163B2 (da)
CA (1) CA1301156C (da)
DE (1) DE3769721D1 (da)
DK (1) DK172896B1 (da)
EG (1) EG18301A (da)
ES (2) ES2031894T3 (da)
GR (1) GR870943B (da)
HU (1) HU198482B (da)
IE (1) IE60038B1 (da)
IL (1) IL82896A (da)
NZ (1) NZ220871A (da)
PT (1) PT85090B (da)
SU (1) SU1581222A3 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8625019D0 (en) * 1986-10-18 1986-11-19 Wellcome Found Compounds
JP2830008B2 (ja) * 1988-04-01 1998-12-02 武田薬品工業株式会社 縮合ピリミジン誘導体
US5223620A (en) * 1988-04-01 1993-06-29 Takeda Chemical Industries, Ltd. Pyrido[2,3-d]pyrimidine compounds useful as intermediates
DK172753B1 (da) * 1988-05-25 1999-06-28 Lilly Co Eli N-(5,6,7,8-tetrahydropyrido[2,3--d]pyrimidin-6-yl-alkanoyl)-glutaminsyrederivater, deres anvendelse, farmaceutiske præparat
US4871746A (en) * 1988-05-31 1989-10-03 The Trustees Of Princeton University N-[N-(tetrahydropyrido[2,3-D]pyrimidinylmethyl)-aminomethylbenzoyl]glutamic acid derivatives as neoplastic growth inhibitors
JP3015957B2 (ja) * 1989-05-29 2000-03-06 武田薬品工業株式会社 ピロロ[2,3―d]ピリミジン誘導体およびその製造法
US5159079A (en) * 1991-12-20 1992-10-27 Eli Lilly And Company 2-piperidones as intermediates for 5-deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acids
WO1993020075A1 (en) * 1992-04-01 1993-10-14 The University Of Sydney 8-substituted-n5-deazapterins as antifolates
CN1962658B (zh) * 2005-11-10 2010-05-12 北京大学 一种四氢吡啶并[3,2-d]嘧啶类化合物及制备抗肿瘤药物的用途
EP3370659A1 (en) 2015-11-06 2018-09-12 Avent, Inc. Ostomy device, apparatus, and system

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3276808D1 (de) * 1981-09-25 1987-08-27 Southern Res Inst Pyrido (2,3-d) pyrimidines
ZA861235B (en) * 1985-03-08 1986-10-29 Univ Princeton Pyrido(2,3-d)pyrimidine derivatives
NZ219971A (en) * 1986-06-06 1989-08-29 Univ Princeton Tetrahydropyrido (2,3-d pyrimidine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
HUT44548A (en) 1988-03-28
DE3769721D1 (de) 1991-06-06
IL82896A0 (en) 1987-12-20
DK172896B1 (da) 1999-09-20
ES2007064A6 (es) 1989-06-01
JPS6333379A (ja) 1988-02-13
PT85090B (pt) 1990-03-08
DK307387D0 (da) 1987-06-17
ES2031894T3 (es) 1993-01-01
CN87104596A (zh) 1988-01-20
CA1301156C (en) 1992-05-19
HU198482B (en) 1989-10-30
JPH07116189B2 (ja) 1995-12-13
KR880000432A (ko) 1988-03-25
IE60038B1 (en) 1994-05-18
GR870943B (en) 1987-10-19
EP0255228B1 (en) 1991-05-02
NZ220871A (en) 1989-07-27
EG18301A (en) 1993-02-28
IL82896A (en) 1991-06-10
PT85090A (en) 1987-07-01
SU1581222A3 (ru) 1990-07-23
IE871586L (en) 1987-12-30
EP0255228A1 (en) 1988-02-03
AU7426287A (en) 1988-01-07
KR950001017B1 (ko) 1995-02-07
CN1014895B (zh) 1991-11-27
AU594163B2 (en) 1990-03-01

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

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