DE3688788D1 - Benzazepinderivate. - Google Patents

Benzazepinderivate.

Info

Publication number
DE3688788D1
DE3688788D1 DE8686117264T DE3688788T DE3688788D1 DE 3688788 D1 DE3688788 D1 DE 3688788D1 DE 8686117264 T DE8686117264 T DE 8686117264T DE 3688788 T DE3688788 T DE 3688788T DE 3688788 D1 DE3688788 D1 DE 3688788D1
Authority
DE
Germany
Prior art keywords
benzazepine derivatives
benzazepine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686117264T
Other languages
English (en)
Other versions
DE3688788T2 (de
Inventor
Jagabandhu Das
David Mack Floyd
John Krapcho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of DE3688788D1 publication Critical patent/DE3688788D1/de
Publication of DE3688788T2 publication Critical patent/DE3688788T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08Oxygen atoms
    • C07D223/10Oxygen atoms attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE86117264T 1985-12-12 1986-12-11 Benzazepinderivate. Expired - Fee Related DE3688788T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80818385A 1985-12-12 1985-12-12
US91713086A 1986-10-09 1986-10-09

Publications (2)

Publication Number Publication Date
DE3688788D1 true DE3688788D1 (de) 1993-09-02
DE3688788T2 DE3688788T2 (de) 1994-03-03

Family

ID=27123095

Family Applications (1)

Application Number Title Priority Date Filing Date
DE86117264T Expired - Fee Related DE3688788T2 (de) 1985-12-12 1986-12-11 Benzazepinderivate.

Country Status (18)

Country Link
EP (1) EP0229329B1 (de)
JP (1) JPH0686435B2 (de)
KR (1) KR900001177B1 (de)
CN (1) CN1017894B (de)
AU (1) AU591726B2 (de)
CA (2) CA1271748C (de)
CZ (1) CZ278686B6 (de)
DE (1) DE3688788T2 (de)
DK (1) DK163731C (de)
ES (1) ES2058059T3 (de)
FI (1) FI83775C (de)
HU (2) HU199806B (de)
IE (1) IE61757B1 (de)
IL (2) IL80668A0 (de)
NO (1) NO168820C (de)
NZ (1) NZ218292A (de)
PL (2) PL150461B1 (de)
PT (1) PT83917B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4752645A (en) * 1986-10-09 1988-06-21 E. R. Squibb & Sons, Inc. Benzazepine derivatives
US4771047A (en) * 1987-07-27 1988-09-13 E. R. Squibb & Sons, Inc. Benzazepine derivatives
US4774239A (en) * 1987-08-26 1988-09-27 E. R. Squibb & Sons, Inc. Benzazepine derivatives
DE3807922A1 (de) * 1988-03-10 1989-09-21 Boehringer Mannheim Gmbh Substituierte heterocyclen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
US4946840A (en) * 1989-04-06 1990-08-07 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
DE60031171T2 (de) * 2000-01-26 2007-08-23 Astellas Pharma Inc. Ace inhibitor-vasopressin antagonist kombinationen
US20030008860A1 (en) 2002-05-09 2003-01-09 Bakker-Arkema Rebecca Guggemos Treatment of congestive heart failure
JP2022055368A (ja) * 2019-02-19 2022-04-08 株式会社三和化学研究所 ベンゾアゼピン誘導体の製造方法及びその中間体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3075967A (en) 1961-06-12 1963-01-29 Olin Mathieson Benzothiazines
US3330823A (en) 1964-12-16 1967-07-11 Squibb & Sons Inc N-amino-loweralkylene-benzo-lactams
CA1271747A (en) * 1985-06-12 1990-07-17 David M. Floyd Benzazepines derivatives

Also Published As

Publication number Publication date
CZ278686B6 (en) 1994-05-18
FI865056A (fi) 1987-06-13
FI83775B (fi) 1991-05-15
ES2058059T3 (es) 1994-11-01
DK595686A (da) 1987-06-13
NO168820C (no) 1992-04-08
PL150461B1 (en) 1990-05-31
DK163731C (da) 1992-08-31
CN86108530A (zh) 1987-06-17
NO168820B (no) 1991-12-30
FI865056A0 (fi) 1986-12-11
KR870005999A (ko) 1987-07-08
NO865012L (no) 1987-06-15
HU199806B (en) 1990-03-28
DE3688788T2 (de) 1994-03-03
EP0229329A1 (de) 1987-07-22
CZ915486A3 (en) 1994-01-19
CN1017894B (zh) 1992-08-19
AU6530386A (en) 1987-06-18
CA1271748A (en) 1990-07-17
JPS62164668A (ja) 1987-07-21
DK163731B (da) 1992-03-30
PL271723A1 (en) 1988-12-08
PT83917A (en) 1987-01-01
NZ218292A (en) 1988-10-28
IL80668A0 (en) 1987-02-27
PL262928A1 (en) 1988-08-04
DK595686D0 (da) 1986-12-11
IL95607A0 (en) 1991-06-30
KR900001177B1 (ko) 1990-02-27
AU591726B2 (en) 1989-12-14
JPH0686435B2 (ja) 1994-11-02
HUT43572A (en) 1987-11-30
HU196760B (en) 1989-01-30
NO865012D0 (no) 1986-12-11
FI83775C (fi) 1991-08-26
IE863224L (en) 1988-04-09
CA1271748C (en) 1990-07-17
EP0229329B1 (de) 1993-07-28
PT83917B (en) 1988-06-23
IE61757B1 (en) 1994-11-30
CA1294617C (en) 1992-01-21
PL151569B1 (en) 1990-09-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee