DK163731C - 1-benzazepin-2-on-derivater samt mellemprodukter til brug ved fremstilling deraf - Google Patents

1-benzazepin-2-on-derivater samt mellemprodukter til brug ved fremstilling deraf

Info

Publication number
DK163731C
DK163731C DK595686A DK595686A DK163731C DK 163731 C DK163731 C DK 163731C DK 595686 A DK595686 A DK 595686A DK 595686 A DK595686 A DK 595686A DK 163731 C DK163731 C DK 163731C
Authority
DK
Denmark
Prior art keywords
benzazepin
intermediates
derivatives
preparing
Prior art date
Application number
DK595686A
Other languages
English (en)
Other versions
DK163731B (da
DK595686D0 (da
DK595686A (da
Inventor
Jagabandhu Das
David Mack Floyd
John Krapcho
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of DK595686D0 publication Critical patent/DK595686D0/da
Publication of DK595686A publication Critical patent/DK595686A/da
Publication of DK163731B publication Critical patent/DK163731B/da
Application granted granted Critical
Publication of DK163731C publication Critical patent/DK163731C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C07D223/10—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK595686A 1985-12-12 1986-12-11 1-benzazepin-2-on-derivater samt mellemprodukter til brug ved fremstilling deraf DK163731C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US80818385A 1985-12-12 1985-12-12
US80818385 1985-12-12
US91713086A 1986-10-09 1986-10-09
US91713086 1986-10-09

Publications (4)

Publication Number Publication Date
DK595686D0 DK595686D0 (da) 1986-12-11
DK595686A DK595686A (da) 1987-06-13
DK163731B DK163731B (da) 1992-03-30
DK163731C true DK163731C (da) 1992-08-31

Family

ID=27123095

Family Applications (1)

Application Number Title Priority Date Filing Date
DK595686A DK163731C (da) 1985-12-12 1986-12-11 1-benzazepin-2-on-derivater samt mellemprodukter til brug ved fremstilling deraf

Country Status (18)

Country Link
EP (1) EP0229329B1 (da)
JP (1) JPH0686435B2 (da)
KR (1) KR900001177B1 (da)
CN (1) CN1017894B (da)
AU (1) AU591726B2 (da)
CA (2) CA1271748A (da)
CZ (1) CZ278686B6 (da)
DE (1) DE3688788T2 (da)
DK (1) DK163731C (da)
ES (1) ES2058059T3 (da)
FI (1) FI83775C (da)
HU (2) HU196760B (da)
IE (1) IE61757B1 (da)
IL (2) IL80668A0 (da)
NO (1) NO168820C (da)
NZ (1) NZ218292A (da)
PL (2) PL150461B1 (da)
PT (1) PT83917B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4752645A (en) * 1986-10-09 1988-06-21 E. R. Squibb & Sons, Inc. Benzazepine derivatives
US4771047A (en) * 1987-07-27 1988-09-13 E. R. Squibb & Sons, Inc. Benzazepine derivatives
US4774239A (en) * 1987-08-26 1988-09-27 E. R. Squibb & Sons, Inc. Benzazepine derivatives
DE3807922A1 (de) * 1988-03-10 1989-09-21 Boehringer Mannheim Gmbh Substituierte heterocyclen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
US4946840A (en) * 1989-04-06 1990-08-07 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
ES2272341T3 (es) * 2000-01-26 2007-05-01 Astellas Pharma Inc. Combinaciones de inhibidores de enzima y de antagonistas.
US20030008860A1 (en) 2002-05-09 2003-01-09 Bakker-Arkema Rebecca Guggemos Treatment of congestive heart failure
JP2022055368A (ja) * 2019-02-19 2022-04-08 株式会社三和化学研究所 ベンゾアゼピン誘導体の製造方法及びその中間体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3075967A (en) 1961-06-12 1963-01-29 Olin Mathieson Benzothiazines
US3330823A (en) 1964-12-16 1967-07-11 Squibb & Sons Inc N-amino-loweralkylene-benzo-lactams
CA1271747C (en) 1985-06-12 1990-07-17 BENZAZEPINE DERIVATIVES

Also Published As

Publication number Publication date
CA1294617C (en) 1992-01-21
JPS62164668A (ja) 1987-07-21
NO865012D0 (no) 1986-12-11
PL271723A1 (en) 1988-12-08
PL262928A1 (en) 1988-08-04
CN1017894B (zh) 1992-08-19
DE3688788T2 (de) 1994-03-03
PT83917A (en) 1987-01-01
NO168820C (no) 1992-04-08
PL150461B1 (en) 1990-05-31
CZ278686B6 (en) 1994-05-18
HUT43572A (en) 1987-11-30
DE3688788D1 (de) 1993-09-02
AU6530386A (en) 1987-06-18
KR900001177B1 (ko) 1990-02-27
DK163731B (da) 1992-03-30
PT83917B (en) 1988-06-23
FI83775C (fi) 1991-08-26
FI865056A (fi) 1987-06-13
NO865012L (no) 1987-06-15
PL151569B1 (en) 1990-09-28
FI865056A0 (fi) 1986-12-11
FI83775B (fi) 1991-05-15
CA1271748C (en) 1990-07-17
AU591726B2 (en) 1989-12-14
EP0229329B1 (en) 1993-07-28
NZ218292A (en) 1988-10-28
JPH0686435B2 (ja) 1994-11-02
ES2058059T3 (es) 1994-11-01
IE863224L (en) 1988-04-09
EP0229329A1 (en) 1987-07-22
IL80668A0 (en) 1987-02-27
CA1271748A (en) 1990-07-17
NO168820B (no) 1991-12-30
CN86108530A (zh) 1987-06-17
HU196760B (en) 1989-01-30
IL95607A0 (en) 1991-06-30
IE61757B1 (en) 1994-11-30
DK595686D0 (da) 1986-12-11
CZ915486A3 (en) 1994-01-19
HU199806B (en) 1990-03-28
DK595686A (da) 1987-06-13
KR870005999A (ko) 1987-07-08

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PBP Patent lapsed