IL87435A - 6-substituted-imidazo (1,2-b) pyridazin-2-yl carbamate esters, their preparation and pharmaceutical compositions containing them - Google Patents

6-substituted-imidazo (1,2-b) pyridazin-2-yl carbamate esters, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL87435A
IL87435A IL87435A IL8743588A IL87435A IL 87435 A IL87435 A IL 87435A IL 87435 A IL87435 A IL 87435A IL 8743588 A IL8743588 A IL 8743588A IL 87435 A IL87435 A IL 87435A
Authority
IL
Israel
Prior art keywords
pyridazin
imidazo
substituted
preparation
pharmaceutical compositions
Prior art date
Application number
IL87435A
Other languages
English (en)
Other versions
IL87435A0 (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL87435A0 publication Critical patent/IL87435A0/xx
Publication of IL87435A publication Critical patent/IL87435A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL87435A 1987-08-15 1988-08-12 6-substituted-imidazo (1,2-b) pyridazin-2-yl carbamate esters, their preparation and pharmaceutical compositions containing them IL87435A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878719368A GB8719368D0 (en) 1987-08-15 1987-08-15 Heterocyclic compounds

Publications (2)

Publication Number Publication Date
IL87435A0 IL87435A0 (en) 1989-01-31
IL87435A true IL87435A (en) 1993-01-31

Family

ID=10622364

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87435A IL87435A (en) 1987-08-15 1988-08-12 6-substituted-imidazo (1,2-b) pyridazin-2-yl carbamate esters, their preparation and pharmaceutical compositions containing them

Country Status (28)

Country Link
US (5) US5091531A (xx)
EP (1) EP0305093B1 (xx)
JP (1) JPS6468375A (xx)
KR (1) KR890003764A (xx)
CN (2) CN1031532A (xx)
AP (1) AP89A (xx)
AT (1) ATE103919T1 (xx)
AU (1) AU613392B2 (xx)
CA (1) CA1336432C (xx)
DD (1) DD289529A5 (xx)
DE (1) DE3888897T2 (xx)
DK (1) DK168954B1 (xx)
ES (1) ES2063039T3 (xx)
FI (1) FI89600C (xx)
GB (1) GB8719368D0 (xx)
HU (1) HU204052B (xx)
IL (1) IL87435A (xx)
MC (1) MC1969A1 (xx)
MX (1) MX12655A (xx)
MY (1) MY103602A (xx)
NO (1) NO168305C (xx)
NZ (1) NZ225808A (xx)
PH (1) PH25741A (xx)
PL (3) PL160045B1 (xx)
PT (1) PT88260B (xx)
RU (3) RU1769759C (xx)
YU (3) YU47200B (xx)
ZA (1) ZA885996B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds
PH27291A (en) * 1989-01-31 1993-05-04 Takeda Chemical Industries Ltd Imidazolpyrimidazines their production and use
EP0440119A1 (en) * 1990-01-31 1991-08-07 Takeda Chemical Industries, Ltd. Imidazopyridazine compounds, their production and use
DE69106902T2 (de) * 1990-03-01 1995-07-06 Takeda Chemical Industries Ltd Imidazopyridazine, ihre Herstellung und Verwendung.
ATE256128T1 (de) * 1998-10-21 2003-12-15 Takeda Chemical Industries Ltd Kondensierte pyridazinderivate, verfahren zu ihrer herstellung und ihre anwendung
EA006483B1 (ru) 2000-06-30 2005-12-29 Уайт Замещенные триазолопиримидины в качестве противораковых средств
JP3767352B2 (ja) 2000-09-18 2006-04-19 トヨタ自動車株式会社 内燃機関の制御装置
WO2002083675A2 (en) * 2001-04-10 2002-10-24 Merck Sharp & Dohme Limited Inhibitors of akt activity
KR20090047509A (ko) * 2006-08-04 2009-05-12 다케다 야쿠힌 고교 가부시키가이샤 융합 헤테로시클릭 유도체 및 이의 용도
JP5357763B2 (ja) * 2006-11-06 2013-12-04 トレロ ファーマシューティカルズ， インコーポレイテッド イミダゾ［１，２−ｂ］ピリダジン誘導体およびピラゾロ［１，５−ａ］ピリダジン誘導体およびプロテインキナーゼインヒビターとしてのこれらの使用
US8431608B2 (en) 2007-08-17 2013-04-30 Icagen Inc. Heterocycles as potassium channel modulators
EP2178373B1 (en) * 2007-08-17 2013-01-23 Icagen, Inc. Heterocycles as potassium channel modulators
UY31676A1 (es) * 2008-02-28 2009-09-30 "derivados de 3-metil-imidiazo-[1,2-b]-piridazina"
EP2277881A4 (en) * 2008-04-18 2011-09-07 Shionogi & Co HETEROCYCLIC COMPOUND HAVING INHIBITORY ACTIVITY ON P13K
UY32049A (es) * 2008-08-14 2010-03-26 Takeda Pharmaceutical Inhibidores de cmet
TW201437211A (zh) * 2013-03-01 2014-10-01 Bayer Pharma AG 經取代咪唑并嗒□

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB305093A (en) * 1928-01-30 1929-07-25 British Continental Motors Ltd Improvements relating to induction passages of sleeve-valve internal combustion engines
US3615639A (en) * 1967-10-23 1971-10-26 Eastman Kodak Co Direct positive silver halide emulsions containing dyes as electron acceptors and spectral sensitizers
US3809691A (en) * 1967-10-23 1974-05-07 Eastman Kodak Co Novel cyanine dyes with fused imidazolo nuclei
DE2043811A1 (en) * 1970-09-03 1972-03-09 E.I. du Pont de Nemours and Co., Wilmington, Del. (V.StA.) Fungicidal and acaricidal alkyl 2-benzimi- - dazole carbomate derivs
US3725407A (en) * 1971-04-08 1973-04-03 American Cyanamid Co 6-substituted amino-3-nitroimidazo(1,2-b)pyridazines and methods of preparing the same
FR2315507A1 (fr) * 1975-06-26 1977-01-21 Roussel Uclaf Imidazo /1,2-b/ pyridazines substituees, procede de preparation et compositions pesticides les renfermant
US4105767A (en) * 1977-03-28 1978-08-08 Merck & Co., Inc. Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group
US4166851A (en) * 1977-05-16 1979-09-04 Merck & Co., Inc. Certain imidazo(1,2a)pyridine derivatives
US4154835A (en) * 1977-10-12 1979-05-15 Merck & Co., Inc. Anthelmintic imidazo [1,2-a] pyridines
US4330543A (en) * 1978-12-14 1982-05-18 Merck & Co., Inc. Imidazoazines and imidazodiazines
US4221796A (en) * 1979-09-19 1980-09-09 E. R. Squibb & Sons, Inc. Substituted imidazolo-pyridines and method
DE3131365A1 (de) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
JPS58126887A (ja) * 1981-09-26 1983-07-28 Takeda Chem Ind Ltd 新規７−デアザプリン誘導体
US4460773A (en) * 1982-02-05 1984-07-17 Lion Corporation 1-Phenyl-1H-pyrazolo [3,4-b]pyrazine derivatives and process for preparing same
US4464372A (en) * 1982-08-16 1984-08-07 Schering Corporation Imidazo[1,2-b]pyridazines
IL69417A (en) * 1982-08-27 1987-12-20 Roussel Uclaf 2-acyl imidazo(1,2-a)pyrimidines,their preparation and pharmaceutical compositions containing them
US4654347A (en) * 1983-06-23 1987-03-31 American Cyanamid Company Aryl and heteroaryl[[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]methanones
DE3401911A1 (de) * 1984-01-20 1985-08-01 A. Nattermann & Cie GmbH, 5000 Köln Substituierte 4,5-dihydro-6-vinyl-3(2h)-pyridazinone und 6-vinyl-3(2h)-pyridazinone sowie verfahren zu ihrer herstellung
DE3423092A1 (de) * 1984-06-22 1986-01-02 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 8-alkylthio-2-piperazino-pyrimido(5,4-d) pyrimidine, ihre herstellung und diese verbindungen enthaltende arzneimittel
US4569934A (en) * 1984-10-09 1986-02-11 American Cyanamid Company Imidazo[1,2-b]pyridazines
DE3446812A1 (de) * 1984-12-21 1986-06-26 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3446778A1 (de) * 1984-12-21 1986-07-03 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3527036A1 (de) * 1985-07-27 1987-02-05 Merck Patent Gmbh 6-arylalkenylpyridazinone
DE3542661A1 (de) * 1985-12-03 1987-06-04 Bayer Ag Imidazopyridazinalkensaeureamide, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung
WO1989001333A1 (en) * 1987-08-07 1989-02-23 The Australian National University IMIDAZO[1,2-b]PYRIDAZINES
WO1989001478A1 (en) * 1987-08-07 1989-02-23 The Australian National University ARYLOXY- AND ARALKYLTHIO-IMIDAZO[1,2-b]PYRIDAZINES
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds

Also Published As

Publication number Publication date
AU613392B2 (en) 1991-08-01
NO883613D0 (no) 1988-08-12
US5538970A (en) 1996-07-23
YU47200B (sh) 1995-01-31
EP0305093B1 (en) 1994-04-06
CN1085901A (zh) 1994-04-27
DK451588D0 (da) 1988-08-12
YU202789A (en) 1990-04-30
YU47212B (sh) 1995-01-31
PT88260A (pt) 1989-09-14
MC1969A1 (fr) 1989-09-29
PL160045B1 (en) 1993-02-26
ATE103919T1 (de) 1994-04-15
DK451588A (da) 1989-02-16
KR890003764A (ko) 1989-04-17
GB8719368D0 (en) 1987-09-23
DE3888897D1 (de) 1994-05-11
CA1336432C (en) 1995-07-25
RU2017741C1 (ru) 1994-08-15
NO883613L (no) 1989-02-16
IL87435A0 (en) 1989-01-31
AP8800098A0 (en) 1988-08-01
AU2097988A (en) 1989-02-16
NO168305C (no) 1992-02-05
NZ225808A (en) 1991-07-26
RU1836372C (ru) 1993-08-23
PT88260B (pt) 1995-03-01
FI89600B (fi) 1993-07-15
CN1031532A (zh) 1989-03-08
PL159008B1 (pl) 1992-11-30
HUT50473A (en) 1990-02-28
EP0305093A1 (en) 1989-03-01
ZA885996B (en) 1990-04-25
PL160044B1 (pl) 1993-02-26
DE3888897T2 (de) 1994-10-20
JPS6468375A (en) 1989-03-14
US5371219A (en) 1994-12-06
HU204052B (en) 1991-11-28
DK168954B1 (da) 1994-07-18
FI883758A (fi) 1989-02-16
PH25741A (en) 1991-10-18
NO168305B (no) 1991-10-28
MX12655A (es) 1993-10-01
US5091531A (en) 1992-02-25
DD289529A5 (de) 1991-05-02
PL274216A1 (en) 1989-05-02
US5447956A (en) 1995-09-05
FI883758A0 (fi) 1988-08-12
RU1769759C (ru) 1992-10-15
YU156988A (en) 1990-04-30
YU47130B (sh) 1994-12-28
AP89A (en) 1990-06-14
YU202889A (en) 1990-04-30
ES2063039T3 (es) 1995-01-01
FI89600C (fi) 1993-10-25
US5380759A (en) 1995-01-10
MY103602A (en) 1993-08-28

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Legal Events

Date Code Title Description
RH Patent void
MM9K Patent not in force due to non-payment of renewal fees