CY1125700T1 - Ανοσοσυζευγματα με ενδοκυτταρικος διασπασιμη αρθρωση - Google Patents
Ανοσοσυζευγματα με ενδοκυτταρικος διασπασιμη αρθρωσηInfo
- Publication number
- CY1125700T1 CY1125700T1 CY20221100764T CY221100764T CY1125700T1 CY 1125700 T1 CY1125700 T1 CY 1125700T1 CY 20221100764 T CY20221100764 T CY 20221100764T CY 221100764 T CY221100764 T CY 221100764T CY 1125700 T1 CY1125700 T1 CY 1125700T1
- Authority
- CY
- Cyprus
- Prior art keywords
- immunoconjugues
- joint
- cleaved
- intracellular
- intracellular cleaved
- Prior art date
Links
- 230000003834 intracellular effect Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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Abstract
Η παρούσα εφεύρεση σχετίζεται με σύζευγμα που έχει δομικό τύπο MAb- CL2A-SN-38, με δομή αναπαριστώμενη από: όπου το MAb είναι hRS7.
Applications Claiming Priority (3)
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US20789009P | 2009-02-13 | 2009-02-13 | |
EP21176545.8A EP3912643B8 (en) | 2009-02-13 | 2009-12-02 | Immunoconjugates with an intracellularly-cleavable linkage |
PCT/US2009/066371 WO2010093395A1 (en) | 2009-02-13 | 2009-12-02 | Immunoconjugates with an intracellularly-cleavable linkage |
Publications (1)
Publication Number | Publication Date |
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CY1125700T1 true CY1125700T1 (el) | 2023-06-09 |
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CY20221100764T CY1125700T1 (el) | 2009-02-13 | 2022-12-05 | Ανοσοσυζευγματα με ενδοκυτταρικος διασπασιμη αρθρωση |
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US (21) | US7999083B2 (el) |
EP (6) | EP3912643B8 (el) |
CN (1) | CN102448494B (el) |
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CY (1) | CY1125700T1 (el) |
DK (3) | DK3912643T3 (el) |
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FR (1) | FR22C1009I2 (el) |
HR (2) | HRP20230487T1 (el) |
HU (3) | HUE060624T2 (el) |
LT (3) | LT3912643T (el) |
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PL (3) | PL3903829T3 (el) |
PT (2) | PT3903829T (el) |
SI (1) | SI3903829T1 (el) |
TR (1) | TR201910848T4 (el) |
WO (1) | WO2010093395A1 (el) |
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