UY32292A - Agonistas de s1p1 y métodos de preparación y uso - Google Patents

Agonistas de s1p1 y métodos de preparación y uso

Info

Publication number
UY32292A
UY32292A UY0001032292A UY32292A UY32292A UY 32292 A UY32292 A UY 32292A UY 0001032292 A UY0001032292 A UY 0001032292A UY 32292 A UY32292 A UY 32292A UY 32292 A UY32292 A UY 32292A
Authority
UY
Uruguay
Prior art keywords
preparation
agonists
use methods
methods
compounds
Prior art date
Application number
UY0001032292A
Other languages
English (en)
Inventor
Lynne Canne Bannen
Diva Sze-Ming Chan
Xiao-Hui Gu
Morrison B Mac
Ng Stephanie
Tie-Lin Wang
Wang Yong
Xu Wei
Original Assignee
Exelixis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exelixis Inc filed Critical Exelixis Inc
Publication of UY32292A publication Critical patent/UY32292A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Abstract

La invención se refiere a compuestos de la fórmula I: así como a métodos de preparación y de uso de los compuestos.
UY0001032292A 2008-12-04 2009-12-04 Agonistas de s1p1 y métodos de preparación y uso UY32292A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20087808P 2008-12-04 2008-12-04

Publications (1)

Publication Number Publication Date
UY32292A true UY32292A (es) 2010-06-30

Family

ID=41511074

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001032292A UY32292A (es) 2008-12-04 2009-12-04 Agonistas de s1p1 y métodos de preparación y uso

Country Status (6)

Country Link
US (1) US20100160369A1 (es)
EP (1) EP2370438A1 (es)
AR (1) AR074543A1 (es)
TW (1) TW201033206A (es)
UY (1) UY32292A (es)
WO (1) WO2010065760A1 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012505836A (ja) 2008-10-17 2012-03-08 アカール ファーマ ピーティーワイ リミテッド Ｓ１ｐ受容体モジュレーターおよびそれらの使用
WO2010042998A1 (en) 2008-10-17 2010-04-22 Akaal Pharma Pty Ltd S1p receptors modulators
CN102361868A (zh) 2009-01-23 2012-02-22 百时美施贵宝公司 作为1-磷酸-鞘氨醇激动剂的吡唑-1，2，4-噁二唑衍生物
WO2010085582A1 (en) 2009-01-23 2010-07-29 Bristol-Myers Squibb Company Substituted oxadiazole derivatives as s1p agonists in the treatment of autoimmune and inflammatory diseases
WO2010085581A1 (en) 2009-01-23 2010-07-29 Bristol-Myers Squibb Company Substituted oxadiazole derivatives as s1p agonists in the treatment of autoimmune and inflammatory diseases
US20100249071A1 (en) * 2009-03-30 2010-09-30 Exelixis, Inc. Modulators of S1P and Methods of Making And Using
US8399451B2 (en) * 2009-08-07 2013-03-19 Bristol-Myers Squibb Company Heterocyclic compounds
ES2539256T3 (es) * 2010-07-20 2015-06-29 Bristol-Myers Squibb Company Compuestos de 3-fenil-1,2,4-oxadiazol sustituidos
KR101275092B1 (ko) * 2011-05-19 2013-06-17 한미정밀화학주식회사 아질사르탄의 개선된 제조방법
US9567304B2 (en) 2012-04-24 2017-02-14 Chugai Seiyaku Kabushiki Kaisha Quinazolinedione derivative
WO2013161851A1 (ja) 2012-04-24 2013-10-31 中外製薬株式会社 ベンズアミド誘導体
KR101731739B1 (ko) 2012-08-17 2017-05-11 액테리온 파마슈티칼 리미티드 (2ｚ,5ｚ)-5-(3-클로로-4-((ｒ)-2,3-디하이드록시프로폭시)벤질리덴)-2-(프로필이미노)-3-(ｏ-톨릴)티아졸리딘-4-온의 제조 방법 및 그 방법에 사용되는 중간체
JP6307088B2 (ja) 2013-10-23 2018-04-04 中外製薬株式会社 キナゾリノンおよびイソキノリノン誘導体
JP2017512183A (ja) 2014-02-13 2017-05-18 リガンド・ファーマシューティカルズ・インコーポレイテッド プロドラッグ化合物およびそれらの使用
CN103936622B (zh) * 2014-05-06 2015-07-15 启东东岳药业有限公司 5-溴-2-氟苯腈合成方法
MA40082B1 (fr) 2014-08-20 2019-09-30 Bristol Myers Squibb Co Nouveau compose de substitution sphingosine phosphate utile traitement maladie rhumatisme
WO2017004608A1 (en) * 2015-07-02 2017-01-05 Exelixis, Inc. Oxadiazole modulators of s1p methods of making and using
WO2017004610A1 (en) * 2015-07-02 2017-01-05 Exelixis, Inc. Tercyclic s1p3-sparing, s1p1 receptor agonists
WO2017004609A1 (en) * 2015-07-02 2017-01-05 Exelixis, Inc. Thiadiazole modulators of s1p and methods of making and using
US10683291B2 (en) * 2015-11-13 2020-06-16 Oppilan Pharma Ltd. Heterocyclic compounds for the treatment of disease
US20210163485A1 (en) * 2017-05-17 2021-06-03 Oppilan Pharma Ltd. Heterocyclic Compounds for the Treatment of Disease
EP3625230A1 (en) * 2017-05-17 2020-03-25 Oppilan Pharma Ltd. Prodrugs for the treatment of disease
US11655258B2 (en) 2017-08-22 2023-05-23 Bayer Aktiengesellschaft Heterocycle derivatives as pesticides
CA3093802A1 (en) 2018-03-13 2019-09-19 Shire Human Genetic Therapies, Inc. Substituted imidazopyridines as inhibitors of plasma kallikrein and uses thereof
CN109912414B (zh) * 2019-04-11 2021-09-17 荆门医药工业技术研究院 一种4-甲醛肟基苯甲酸乙酯的制备方法和应用
AR119140A1 (es) 2019-06-13 2021-11-24 Pi Industries Ltd Compuestos heterocíclicos fusionados y su uso como agentes de control de plagas
WO2021055589A1 (en) 2019-09-18 2021-03-25 Shire Human Genetic Therapies, Inc. Heteroaryl plasma kallikrein inhibitors
CN114728962A (zh) 2019-09-18 2022-07-08 武田药品工业有限公司 血浆激肽释放酶抑制剂及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107288A (en) 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
CA2539438A1 (en) * 2003-10-01 2005-04-14 Merck And Co., Inc. 3,5-aryl, heteroaryl or cycloalkyl substituted-1,2,4-oxadiazoles as s1p receptor agonists
TWI382984B (zh) * 2006-04-03 2013-01-21 Astellas Pharma Inc 雜環化合物

Also Published As

Publication number Publication date
WO2010065760A1 (en) 2010-06-10
US20100160369A1 (en) 2010-06-24
EP2370438A1 (en) 2011-10-05
AR074543A1 (es) 2011-01-26
TW201033206A (en) 2010-09-16

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20181219