CY1111056T1 - Εμβολιο κυστιδιου εξωτερικης μεμβρανης (omv) που περιλαμβανει πρωτεϊνες εξωτερικης μεμβρανης απο ν. meningitidis οροομαδας β - Google Patents

Εμβολιο κυστιδιου εξωτερικης μεμβρανης (omv) που περιλαμβανει πρωτεϊνες εξωτερικης μεμβρανης απο ν. meningitidis οροομαδας β

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Publication number
CY1111056T1
CY1111056T1 CY20101101003T CY101101003T CY1111056T1 CY 1111056 T1 CY1111056 T1 CY 1111056T1 CY 20101101003 T CY20101101003 T CY 20101101003T CY 101101003 T CY101101003 T CY 101101003T CY 1111056 T1 CY1111056 T1 CY 1111056T1
Authority
CY
Cyprus
Prior art keywords
outer membrane
vaccine
omv
meningitidis
serial
Prior art date
Application number
CY20101101003T
Other languages
English (en)
Inventor
Mariagrazia Pizza
Rino Rappuoli
Marzia Giuliani
Original Assignee
Novartis Vaccines And Diagnostics S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0001067A external-priority patent/GB0001067D0/en
Priority claimed from GBGB0005699.4A external-priority patent/GB0005699D0/en
Application filed by Novartis Vaccines And Diagnostics S.R.L. filed Critical Novartis Vaccines And Diagnostics S.R.L.
Publication of CY1111056T1 publication Critical patent/CY1111056T1/el

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

Μία σύνθεση η οποία περιλαμβάνει κυστίδια εξωτερικής μεμβράνης (OMVs) από Neisseria meningitidis οροομάδας Β, και (β) ένα ανοσογόνο συστατικό που επιλέγεται από άλλες Neisseria πρωτεΐνες, ή ανοσογόνα θραύσματα αυτών. Τα συστατικά (β) κατά προτίμηση περιλαμβάνουν μία πρωτεΐνη από ένα στέλεχος NmB διαφορετικό από αυτό από το οποίο προέρχεται το OMV συστατικό (α). Τα OMVs κατά προτίμηση λαμβάνονται με δεοξυχολική εκχύλιση. Προαιρετικά, η σύνθεση μπορεί επίσης να περιλαμβάνει ένα προστατευτικό αντιγόνο κατά άλλων παθογόνων.
CY20101101003T 2000-01-17 2010-11-04 Εμβολιο κυστιδιου εξωτερικης μεμβρανης (omv) που περιλαμβανει πρωτεϊνες εξωτερικης μεμβρανης απο ν. meningitidis οροομαδας β CY1111056T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0001067A GB0001067D0 (en) 2000-01-17 2000-01-17 Supplemented norwegian vaccine
GBGB0005699.4A GB0005699D0 (en) 2000-03-09 2000-03-09 Supplemented OMV vaccines
EP01942562A EP1248647B1 (en) 2000-01-17 2001-01-17 Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins

Publications (1)

Publication Number Publication Date
CY1111056T1 true CY1111056T1 (el) 2015-06-11

Family

ID=26243421

Family Applications (3)

Application Number Title Priority Date Filing Date
CY20101101003T CY1111056T1 (el) 2000-01-17 2010-11-04 Εμβολιο κυστιδιου εξωτερικης μεμβρανης (omv) που περιλαμβανει πρωτεϊνες εξωτερικης μεμβρανης απο ν. meningitidis οροομαδας β
CY20141100751T CY1115842T1 (el) 2000-01-17 2014-09-17 Συμπληρωμενο ομv εμβολιο κατα μηνιγγιtiδοκοκκου
CY20161100845T CY1117957T1 (el) 2000-01-17 2016-08-29 Συμπληρωμενο omv εμβολιο εναντι μηνιγγιοκοκκου

Family Applications After (2)

Application Number Title Priority Date Filing Date
CY20141100751T CY1115842T1 (el) 2000-01-17 2014-09-17 Συμπληρωμενο ομv εμβολιο κατα μηνιγγιtiδοκοκκου
CY20161100845T CY1117957T1 (el) 2000-01-17 2016-08-29 Συμπληρωμενο omv εμβολιο εναντι μηνιγγιοκοκκου

Country Status (17)

Country Link
US (4) US8273360B2 (el)
EP (6) EP2281570A3 (el)
JP (6) JP2003520248A (el)
CN (2) CN102172398A (el)
AT (1) ATE476988T1 (el)
AU (2) AU784518B2 (el)
BR (2) BR0107679A (el)
CA (2) CA2871789C (el)
CY (3) CY1111056T1 (el)
DE (1) DE60142772D1 (el)
DK (3) DK1248647T3 (el)
ES (2) ES2507100T3 (el)
MX (1) MXPA02006962A (el)
NZ (1) NZ520466A (el)
PT (3) PT1897555E (el)
RU (1) RU2279889C2 (el)
WO (1) WO2001052885A1 (el)

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US8273360B2 (en) 2012-09-25
BRPI0107679B8 (pt) 2021-05-25
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AU2009200692B2 (en) 2011-04-14
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RU2002122111A (ru) 2004-03-10
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DK1248647T3 (da) 2010-09-27
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