DE69506212T2 - Impfstoff gegen gram-negative bakterielle infektionen - Google Patents

Impfstoff gegen gram-negative bakterielle infektionen

Info

Publication number
DE69506212T2
DE69506212T2 DE69506212T DE69506212T DE69506212T2 DE 69506212 T2 DE69506212 T2 DE 69506212T2 DE 69506212 T DE69506212 T DE 69506212T DE 69506212 T DE69506212 T DE 69506212T DE 69506212 T2 DE69506212 T2 DE 69506212T2
Authority
DE
Germany
Prior art keywords
bacterial infections
negative bacterial
gram
vaccine
lps
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69506212T
Other languages
English (en)
Other versions
DE69506212D1 (de
Inventor
Apurba Bhattacharjee
Alan Cross
Erald Sadoff
Wendell Zollinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Army
Original Assignee
US Department of Army
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Army filed Critical US Department of Army
Application granted granted Critical
Publication of DE69506212D1 publication Critical patent/DE69506212D1/de
Publication of DE69506212T2 publication Critical patent/DE69506212T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/803—Antibody or antigen-binding fragment thereof that binds gram-negative bacteria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DE69506212T 1994-04-20 1995-04-20 Impfstoff gegen gram-negative bakterielle infektionen Expired - Lifetime DE69506212T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23040294A 1994-04-20 1994-04-20
PCT/US1995/004446 WO1995029662A2 (en) 1994-04-20 1995-04-20 Vaccine against gram-negative bacterial infections

Publications (2)

Publication Number Publication Date
DE69506212D1 DE69506212D1 (de) 1999-01-07
DE69506212T2 true DE69506212T2 (de) 1999-08-05

Family

ID=22865082

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69506212T Expired - Lifetime DE69506212T2 (de) 1994-04-20 1995-04-20 Impfstoff gegen gram-negative bakterielle infektionen

Country Status (9)

Country Link
US (3) US7025963B1 (de)
EP (1) EP0710118B1 (de)
AT (1) ATE173634T1 (de)
AU (1) AU2356095A (de)
DE (1) DE69506212T2 (de)
DK (1) DK0710118T3 (de)
ES (1) ES2128055T3 (de)
GR (1) GR3029477T3 (de)
WO (1) WO1995029662A2 (de)

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CA2289760A1 (en) * 1997-05-16 1998-11-19 Medical Defense Technologies, Llc. Vaccine against lipopolysaccharide core
US6749831B1 (en) 1997-05-16 2004-06-15 Medical Defense Technology, Llc Vaccine against lipopolysaccharide core
EP2261355A3 (de) 1998-05-01 2012-01-11 Novartis Vaccines and Diagnostics, Inc. Antigene und Zusammensetzungen gegen Neisseria meningitidis
US20070026021A1 (en) * 1998-05-01 2007-02-01 Chiron S.R.I. Neisseria meningitidis antigens and compositions
ES2485940T3 (es) 1998-05-29 2014-08-14 Novartis Vaccines And Diagnostics, Inc. Combinación de vacunas contra Meningitis B/C
CN102580072A (zh) 1999-05-19 2012-07-18 诺华疫苗和诊断有限公司 组合式奈瑟球菌组合物
CA2864069A1 (en) * 1999-10-29 2001-05-03 Novartis Vaccines And Diagnostics S.R.L. Neisserial antigenic peptides
GB9928196D0 (en) * 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
ES2507100T3 (es) * 2000-01-17 2014-10-14 Novartis Vaccines And Diagnostics S.R.L. Vacuna OMV suplementada contra meningococo
MX339524B (es) * 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
GB0220194D0 (en) * 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
US8828226B2 (en) 2003-03-01 2014-09-09 The Trustees Of Boston University System for assessing the efficacy of stored red blood cells using microvascular networks
GB0316560D0 (en) 2003-07-15 2003-08-20 Chiron Srl Vesicle filtration
GB0419627D0 (en) * 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
US9616116B2 (en) * 2005-10-24 2017-04-11 University Of Maryland, Baltimore Detoxified endotoxin immunogenic compositions and uses thereof
US20090220522A1 (en) * 2005-10-24 2009-09-03 Cross Alan S Detoxified Endotoxin Vaccine and Adjuvant and Uses thereof
US9475864B2 (en) * 2008-09-05 2016-10-25 University Of Massachusetts Methods, compositions and vaccines relating to Neisseria meningitidis antibodies
US8258705B2 (en) * 2009-04-29 2012-09-04 Hubbell Incorporated Scotopically enhanced emergency light and control thereof
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
WO2011046841A1 (en) 2009-10-12 2011-04-21 New Health Sciences, Inc. Blood storage bag system and depletion devices with oxygen and carbon dioxide depletion capabilities
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
AU2010306920A1 (en) 2009-10-12 2012-05-31 New Health Sciences, Inc. Oxygen depletion devices and methods for removing oxygen from red blood cells
EP2608816B1 (de) 2010-08-25 2023-07-05 Hemanext Inc. Verfahren zur erhöhung der qualität von erythrozyten und zur verlängerung ihrer lebensdauer während der lagerung
EP2613805B1 (de) 2010-09-10 2019-10-23 GlaxoSmithKline Biologicals SA Nada und/oder nhba überexprimierende meningococcus und davon abgeleiteten aussenmembranvesikeln
PT3539381T (pt) 2010-11-05 2023-09-26 Hemanext Inc Irradiação de glóbulos vermelhos e armazenamento anaeróbico
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
AU2012294269B2 (en) 2011-08-10 2016-11-24 Hemanext Inc. Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
AU2013320313B2 (en) 2012-09-18 2018-07-12 Glaxosmithkline Biologicals Sa Outer membrane vesicles
US9877476B2 (en) 2013-02-28 2018-01-30 New Health Sciences, Inc. Gas depletion and gas addition devices for blood treatment
CA2923129C (en) 2013-09-08 2020-06-09 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
MX2017011595A (es) 2015-03-10 2018-06-15 New Health Sciences Inc Kits, dispositivos descartables para reducir el oxígeno y métodos para usarlos.
JP7175611B2 (ja) 2015-04-23 2022-11-21 ヘマネクスト インコーポレイテッド 嫌気性血液保存容器
BR112017024091B1 (pt) 2015-05-18 2022-09-20 Hemanext Inc Método para reduzir citocinas em um produto de sangue total armazenado, composição de sangue total armazenado e uso de um produto de sangue total armazenado
JP7148499B2 (ja) 2016-05-27 2022-10-05 ヘマネクスト インコーポレイテッド 嫌気性血液貯蔵および病原体不活性化方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB109688A (en) 1916-11-04 1917-09-27 Herbert Senior Vincent Improvements in Steam Jacketed Heating or Boiling Pans and like Receptacles.
EP0109688A3 (de) * 1982-11-23 1986-12-03 The Wellcome Foundation Limited Komplexe, Verfahren zu deren Herstellung und diese Komplexe enthaltende Zusammensetzungen
US4707543A (en) * 1985-09-17 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines
US4918163A (en) * 1985-09-27 1990-04-17 Pfizer Inc. Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria
EP0367757B1 (de) * 1986-05-23 1994-11-02 SANOFI ANIMAL HEALTH, Inc. GEMEINSAME IMPFUNG UNTER VERWENDUNG EINER PRAPARATION GRAM-NEGATIVER BAKTERIEN OHNE O-SPEZIFISCHEN KOHlEHYDRATSEITENKETTEN
US4929604A (en) * 1986-05-28 1990-05-29 Board Of Regents, The University Of Texas System Lipopolysaccharides of reduced toxicity and the production thereof
US4912094B1 (en) * 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
GB8918232D0 (en) * 1989-08-10 1989-09-20 Opal Stephen M Pharmaceutical product for the treatment of septic shock

Also Published As

Publication number Publication date
US20060159702A1 (en) 2006-07-20
EP0710118A1 (de) 1996-05-08
ES2128055T3 (es) 1999-05-01
EP0710118B1 (de) 1998-11-25
AU2356095A (en) 1995-11-29
US7018636B1 (en) 2006-03-28
WO1995029662A3 (en) 1995-11-30
DE69506212D1 (de) 1999-01-07
WO1995029662A2 (en) 1995-11-09
GR3029477T3 (en) 1999-05-28
US7025963B1 (en) 2006-04-11
ATE173634T1 (de) 1998-12-15
DK0710118T3 (da) 1999-08-09
US7235644B2 (en) 2007-06-26

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