CR11232A - Compuestos de tiazolopirina modulares de sirtuina - Google Patents

Compuestos de tiazolopirina modulares de sirtuina

Info

Publication number
CR11232A
CR11232A CR11232A CR11232A CR11232A CR 11232 A CR11232 A CR 11232A CR 11232 A CR11232 A CR 11232A CR 11232 A CR11232 A CR 11232A CR 11232 A CR11232 A CR 11232A
Authority
CR
Costa Rica
Prior art keywords
compounds
modular
thiazolopirine
sirtuina
modular compounds
Prior art date
Application number
CR11232A
Other languages
English (en)
Spanish (es)
Inventor
Jean Bemis
Jeremy S Disch
Pui Yee Ng
Christopher Oalmann
Robert B Perni
Chi B Vu
Original Assignee
Sirtris Pharmaceuticas Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sirtris Pharmaceuticas Inc filed Critical Sirtris Pharmaceuticas Inc
Publication of CR11232A publication Critical patent/CR11232A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CR11232A 2007-06-20 2010-01-20 Compuestos de tiazolopirina modulares de sirtuina CR11232A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93663607P 2007-06-20 2007-06-20

Publications (1)

Publication Number Publication Date
CR11232A true CR11232A (es) 2010-05-24

Family

ID=39798234

Family Applications (1)

Application Number Title Priority Date Filing Date
CR11232A CR11232A (es) 2007-06-20 2010-01-20 Compuestos de tiazolopirina modulares de sirtuina

Country Status (23)

Country Link
US (2) US7893086B2 (enExample)
EP (1) EP2170905A2 (enExample)
JP (1) JP5498940B2 (enExample)
KR (1) KR20100051048A (enExample)
CN (2) CN103833775A (enExample)
AR (1) AR067107A1 (enExample)
AU (1) AU2008266749C1 (enExample)
BR (1) BRPI0813651A2 (enExample)
CA (1) CA2691733A1 (enExample)
CL (1) CL2008001822A1 (enExample)
CO (1) CO6251248A2 (enExample)
CR (1) CR11232A (enExample)
DO (1) DOP2009000284A (enExample)
EA (1) EA018922B1 (enExample)
IL (1) IL202730A0 (enExample)
MA (1) MA31506B1 (enExample)
MX (1) MX2009013977A (enExample)
NZ (1) NZ581990A (enExample)
PE (1) PE20090694A1 (enExample)
TW (1) TW200916472A (enExample)
UY (1) UY31169A1 (enExample)
WO (1) WO2008156869A2 (enExample)
ZA (1) ZA200908883B (enExample)

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CL2008001821A1 (es) 2007-06-20 2009-03-13 Sirtris Pharmaceuticals Inc Compuestos derivados de imidazo[2,1-b]-tiazol; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de diabetes, sindrome metabolico, resistencia a la insulina, entre otras.
AR067354A1 (es) 2007-06-29 2009-10-07 Sunesis Pharmaceuticals Inc Compuestos utiles como inhibidores de la raf quinasa
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EP2273992B1 (en) * 2008-05-01 2016-05-25 Glaxosmithkline LLC Quinolines and related analogs as sirtuin modulators
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KR101329524B1 (ko) 2011-05-23 2013-11-13 연세대학교 산학협력단 미분화 전능성 줄기세포의 선택적 세포사멸 방법
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CN108452311A (zh) 2012-11-13 2018-08-28 纽斯尔特科学公司 用于增强能量代谢的组合物和方法
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WO2024005905A2 (en) * 2022-04-29 2024-01-04 The Regents Of The University Of Michigan Small molecule sirtuin inhibitors and uses thereof

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CN101801981A (zh) 2010-08-11
BRPI0813651A2 (pt) 2014-12-30
AU2008266749B2 (en) 2012-03-15
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CA2691733A1 (en) 2008-12-24
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