CN103833775A - 瑟土因调节性化合物 - Google Patents
瑟土因调节性化合物 Download PDFInfo
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- CN103833775A CN103833775A CN201310744228.7A CN201310744228A CN103833775A CN 103833775 A CN103833775 A CN 103833775A CN 201310744228 A CN201310744228 A CN 201310744228A CN 103833775 A CN103833775 A CN 103833775A
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| CN107496410A (zh) * | 2017-09-21 | 2017-12-22 | 上海华堇生物技术有限责任公司 | 洋槐黄素的药物用途 |
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| WO2007041643A1 (en) * | 2005-10-03 | 2007-04-12 | University Of Tennessee Research Foundation | Dietary calcium for reducing the production of reactive oxygen species |
| TW200918542A (en) | 2007-06-20 | 2009-05-01 | Sirtris Pharmaceuticals Inc | Sirtuin modulating compounds |
| CL2008001822A1 (es) * | 2007-06-20 | 2009-03-13 | Sirtris Pharmaceuticals Inc | Compuestos derivados de tiazolo[5,4-b]piridina; composicion farmaceutica que comprende a dichos compuestos; y uso del compuesto en el tratamiento de la resistencia a la insulina, sindrome metabolico, diabetes, entre otras. |
| TWI444379B (zh) | 2007-06-29 | 2014-07-11 | Sunesis Pharmaceuticals Inc | 有用於作為Ｒａｆ激酶抑制劑之化合物 |
| AU2008279776B2 (en) * | 2007-07-19 | 2013-05-23 | Merck Sharp & Dohme Corp. | Heterocyclic amide compounds as protein kinase inhibitors |
| BRPI0820377A2 (pt) * | 2007-11-08 | 2015-05-19 | Sirtris Pharmaceutical Inc | Tiazolopiridinas solubilizadas |
| CA2723135A1 (en) | 2008-05-01 | 2009-11-05 | Sirtris Pharmaceuticals, Inc. | Quenolines and related analogs as sirtuin modulators |
| CA2729128C (en) | 2008-07-03 | 2016-05-31 | Sirtris Pharmaceuticals, Inc. | Benzimidazoles and related analogs as sirtuin modulators |
| CA2738809C (en) | 2008-09-29 | 2015-11-24 | Sirtris Pharmaceuticals, Inc. | Quinazolinone, quinolone and related analogs as sirtuin modulators |
| AU2009333588A1 (en) | 2008-12-08 | 2011-07-21 | Northwestern University | Method of modulating HSF-1 |
| MX2011006555A (es) | 2008-12-19 | 2011-08-03 | Sirtris Pharmaceuticals Inc | Compuestos de tiazolopiridina moduladores de sirtuina. |
| WO2011059839A1 (en) | 2009-10-29 | 2011-05-19 | Sirtris Pharmaceuticals, Inc. | Bicyclic pyridines and analogs as sirtuin modulators |
| JP2013522376A (ja) * | 2010-03-24 | 2013-06-13 | メディカル ユニバーシティー オブ サウス カロライナ | 変性疾患を治療するための組成物および方法 |
| EP2558589A4 (en) * | 2010-04-15 | 2014-01-01 | Glaxosmithkline Llc | SIRTUIN ACTIVATORS AND ACTIVATION ASSAYS FOR THIS |
| KR20130101442A (ko) * | 2010-05-03 | 2013-09-13 | 큐알엔에이, 인크. | 시르투인 (sirt)에 대한 자연 안티센스 전사체의 저해에 의한 시르투인 (sirt) 관련된 질환의 치료 |
| EP2423214A1 (en) | 2010-08-13 | 2012-02-29 | Solvay SA | Light emitting materials for Electronics |
| TW201223956A (en) | 2010-08-13 | 2012-06-16 | Solvay | Light emitting materials for electronics |
| KR20120047341A (ko) * | 2010-10-21 | 2012-05-14 | 경상대학교산학협력단 | 니코틴아미드를 유효성분으로 포함하는 알킬화 약물-유도성 신경퇴행의 예방 또는 치료용 조성물 |
| CN103391777A (zh) | 2011-02-02 | 2013-11-13 | 普林斯顿大学理事会 | 作为病毒产生调节剂的去乙酰化酶调节剂 |
| KR101329524B1 (ko) | 2011-05-23 | 2013-11-13 | 연세대학교 산학협력단 | 미분화 전능성 줄기세포의 선택적 세포사멸 방법 |
| RU2017129378A (ru) | 2011-07-15 | 2019-02-04 | Нусерт Сайенсиз, Инк. | Композиции и способы модулирования метаболических путей |
| CN104010651A (zh) | 2011-09-07 | 2014-08-27 | 康奈尔大学 | 通过靶向Sirt5治疗癌症的方法 |
| EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| US9198454B2 (en) | 2012-03-08 | 2015-12-01 | Nusirt Sciences, Inc. | Compositions, methods, and kits for regulating energy metabolism |
| AU2013344753B2 (en) | 2012-11-13 | 2018-09-27 | Nusirt Sciences, Inc. | Compositions and methods for increasing energy metabolism |
| CA2902879C (en) | 2013-03-15 | 2023-09-26 | Nusirt Sciences, Inc. | Leucine and nicotinic acid reduces lipid levels |
| CN106456997B (zh) | 2014-02-27 | 2018-12-28 | 纽斯尔特科学公司 | 用于减少或预防肝性脂肪变性的组合物和方法 |
| WO2015143654A1 (en) * | 2014-03-26 | 2015-10-01 | Merck Sharp & Dohme Corp. | TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF |
| AU2015270130A1 (en) | 2014-06-02 | 2016-12-15 | Glaxosmithkline Intellectual Property (No.2) Limited | Preparation and use of crystalline beta-D-nicotinamide riboside |
| JP6559713B2 (ja) | 2014-06-06 | 2019-08-14 | グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ （Ｎｏ．２） Ｌｉｍｉｔｅｄ | ニコチンアミドリボシド類似体ならびにその医薬組成物および使用 |
| US20180072718A1 (en) | 2016-09-09 | 2018-03-15 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
| US11459293B2 (en) * | 2017-10-27 | 2022-10-04 | Immunebridge Inc. | Compositions and methods of making expanded hematopoietic stem cells using derivatives of fluorene |
| SMT202200294T1 (it) | 2018-02-20 | 2022-11-18 | Incyte Corp | Derivati di n-(fenil)-2-(fenil)pirimidina-4-carbossammide e composti correlati come inibitori di hpk1 per trattare il cancro |
| US10899755B2 (en) | 2018-08-08 | 2021-01-26 | Incyte Corporation | Benzothiazole compounds and uses thereof |
| KR20220059480A (ko) | 2019-08-06 | 2022-05-10 | 인사이트 코포레이션 | 고체 형태의 hpk1 억제제 |
| WO2024005905A2 (en) * | 2022-04-29 | 2024-01-04 | The Regents Of The University Of Michigan | Small molecule sirtuin inhibitors and uses thereof |
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| US3164603A (en) * | 1965-01-05 | xnhcox | ||
| DE1108698B (de) | 1959-09-03 | 1961-06-15 | Hoechst Ag | Verfahren zur Herstellung von 2-(2'-Aminoaryl)-4, 5-arylen-1, 2, 3-triazolen |
| FR1439129A (fr) | 1965-04-02 | 1966-05-20 | Chimetron | Nouveaux sulfonylbenzimidazoles |
| FR1476529A (fr) | 1965-04-24 | 1967-04-14 | Chimetron Sarl | Nouveaux dérivés benzimidazole-sulfoniques et sulfamides correspondants |
| FR1450625A (fr) | 1965-06-18 | 1966-06-24 | Chimetron Sarl | Sulfonamidothiazolyl-2 benzimidazoles |
| US3503929A (en) * | 1965-10-21 | 1970-03-31 | Minnesota Mining & Mfg | Polyimidazoquinazolines and polyamidobenzimidazoles |
| US3517007A (en) * | 1968-04-05 | 1970-06-23 | American Home Prod | 5 - acetamido - 4 - pyrimidinecarboxamides,5 - acetamido - 4 - pyrimidinecarboxylic acid hydrazides and related compounds |
| US3928228A (en) * | 1969-04-28 | 1975-12-23 | Sterling Drug Inc | 4,4{40 -Stilbenebis-pyridooxazoles and related optical brighteners and polymeric compositions brightened thereby |
| US3712888A (en) * | 1970-12-14 | 1973-01-23 | American Cyanamid Co | Bis-pyridoxazole-stilbene derivatives for optical brightening |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107496410A (zh) * | 2017-09-21 | 2017-12-22 | 上海华堇生物技术有限责任公司 | 洋槐黄素的药物用途 |
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| US8268862B2 (en) | 2012-09-18 |
| CO6251248A2 (es) | 2011-02-21 |
| UY31169A1 (es) | 2009-01-30 |
| US7893086B2 (en) | 2011-02-22 |
| DOP2009000284A (es) | 2010-02-28 |
| WO2008156869A2 (en) | 2008-12-24 |
| EA201070035A1 (ru) | 2010-06-30 |
| ZA200908883B (en) | 2010-08-25 |
| EP2170905A2 (en) | 2010-04-07 |
| PE20090694A1 (es) | 2009-06-20 |
| JP2010530432A (ja) | 2010-09-09 |
| EA018922B1 (ru) | 2013-11-29 |
| US20110152254A1 (en) | 2011-06-23 |
| JP5498940B2 (ja) | 2014-05-21 |
| US20090105246A1 (en) | 2009-04-23 |
| MX2009013977A (es) | 2010-04-09 |
| AU2008266749A1 (en) | 2008-12-24 |
| TW200916472A (en) | 2009-04-16 |
| BRPI0813651A2 (pt) | 2014-12-30 |
| AR067107A1 (es) | 2009-09-30 |
| WO2008156869A3 (en) | 2009-05-14 |
| KR20100051048A (ko) | 2010-05-14 |
| NZ581990A (en) | 2012-07-27 |
| CA2691733A1 (en) | 2008-12-24 |
| CL2008001822A1 (es) | 2009-03-13 |
| AU2008266749B2 (en) | 2012-03-15 |
| IL202730A0 (en) | 2010-06-30 |
| MA31506B1 (fr) | 2010-07-01 |
| CR11232A (es) | 2010-05-24 |
| CN101801981A (zh) | 2010-08-11 |
| AU2008266749C1 (en) | 2012-11-01 |
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