SE8800613D0
(sv)
|
1988-02-23 |
1988-02-23 |
Wallac Oy |
A novel spectrofluorometric method and compounds that are of value for the method
|
JPH03287584A
(ja)
|
1990-04-05 |
1991-12-18 |
Banyu Pharmaceut Co Ltd |
置換アリルアミン誘導体
|
US5250534A
(en)
|
1990-06-20 |
1993-10-05 |
Pfizer Inc. |
Pyrazolopyrimidinone antianginal agents
|
US6200980B1
(en)
|
1995-06-07 |
2001-03-13 |
Cell Pathways, Inc. |
Method of treating a patient having precancerous lesions with phenyl purinone derivatives
|
WO1998049166A1
(en)
|
1997-04-25 |
1998-11-05 |
Pfizer Limited |
PYRAZOLOPYRIMIDINONES WHICH INHIBIT TYPE 5 CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE PHOSPHODIESTERASE (cGMP PDE5) FOR THE TREATMENT OF SEXUAL DYSFUNCTION
|
JP3721077B2
(ja)
|
1998-04-20 |
2005-11-30 |
ファイザー・インク |
性的不全を治療するためのピラゾロピリミジノンcGMPPDE5阻害剤
|
JP2000038350A
(ja)
|
1998-05-18 |
2000-02-08 |
Yoshitomi Pharmaceut Ind Ltd |
糖尿病治療薬
|
GB9823101D0
(en)
|
1998-10-23 |
1998-12-16 |
Pfizer Ltd |
Pharmaceutically active compounds
|
GB9823102D0
(en)
|
1998-10-23 |
1998-12-16 |
Pfizer Ltd |
Pharmaceutically active compounds
|
CZ27399A3
(cs)
|
1999-01-26 |
2000-08-16 |
Ústav Experimentální Botaniky Av Čr |
Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
|
IN187433B
(es)
|
1999-09-10 |
2002-04-27 |
Cipla Ltd |
|
WO2001019827A1
(en)
|
1999-09-13 |
2001-03-22 |
Cipla Ltd. |
A novel process for the synthesis of sildenafil citrate
|
KR20020063854A
(ko)
|
1999-09-17 |
2002-08-05 |
애보트 게엠베하 운트 콤파니 카게 |
치료제로서의 키나제 억제제
|
AU768851B2
(en)
|
1999-09-24 |
2004-01-08 |
Nihon Nohyaku Co., Ltd. |
Aromatic diamide derivatives or salts thereof, agricultural/horticultural chemicals and method of using the same
|
CA2387353A1
(en)
|
1999-10-11 |
2001-04-19 |
Charlotte Moira Norfor Allerton |
Pharmaceutically active compounds
|
TWI265925B
(en)
|
1999-10-11 |
2006-11-11 |
Pfizer |
Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them
|
IL152925A
(en)
|
1999-10-21 |
2010-04-15 |
Pfizer |
Pharmaceutical preparations for the treatment of neurological disease containing an inhibitor of ring guanizine '3', 5 '- monophosphate phosphodiesterase 5 and one of gabapentin or pregabalin
|
KR100523718B1
(ko)
|
1999-12-22 |
2005-10-26 |
니혼노야쿠가부시키가이샤 |
방향족 디아미드 유도체, 농원예용 약제 및 이의 사용방법
|
CO5271697A1
(es)
|
2000-01-12 |
2003-04-30 |
Pfizer Prod Inc |
Composiciones y procedimientos para el tratamiento de afecciones que responden a un aumento de testosterona
|
US20020013327A1
(en)
|
2000-04-18 |
2002-01-31 |
Lee Andrew G. |
Compositions and methods for treating female sexual dysfunction
|
NZ522783A
(en)
|
2000-06-28 |
2004-07-30 |
Smithkline Beecham P |
Wet milling process for pharmaceuticals with agitator or chamber having nylon with internal lubricant
|
WO2002016348A1
(en)
|
2000-08-09 |
2002-02-28 |
Astrazeneca Ab |
Antiangiogenic bicyclic derivatives
|
AU2001284417A1
(en)
|
2000-09-05 |
2002-03-22 |
Taisho Pharmaceutical Co. Ltd. |
Hair growth stimulants
|
US6548508B2
(en)
|
2000-10-20 |
2003-04-15 |
Pfizer, Inc. |
Use of PDE V inhibitors for improved fecundity in mammals
|
CN1481244A
(zh)
|
2000-12-19 |
2004-03-10 |
Ĭ��ר���ɷ�����˾ |
含有吡唑并[4,3-d]嘧啶和抗血栓形成剂、钙拮抗剂、前列腺素或前列腺素衍生物的药物制剂
|
JP2004518662A
(ja)
|
2000-12-19 |
2004-06-24 |
スミスクライン ビーチャム パブリック リミテッド カンパニー |
Gsk−3阻害剤としてのピラゾロ[3,4−c]ピリジン
|
US6784185B2
(en)
|
2001-03-16 |
2004-08-31 |
Pfizer Inc. |
Pharmaceutically active compounds
|
US6770645B2
(en)
|
2001-03-16 |
2004-08-03 |
Pfizer Inc. |
Pharmaceutically active compounds
|
JP4196678B2
(ja)
|
2001-04-26 |
2008-12-17 |
味の素株式会社 |
複素環化合物
|
WO2002090347A1
(en)
|
2001-04-30 |
2002-11-14 |
Fujisawa Pharmaceutical Co., Ltd. |
Amide compounds
|
FR2825706B1
(fr)
|
2001-06-06 |
2003-12-12 |
Pf Medicament |
Nouveaux derives de benzothienyle ou d'indole, leur preparation et leur utilisation comme inhibiteurs de proteines prenyl transferase
|
IL161155A0
(en)
|
2001-11-02 |
2004-08-31 |
Pfizer Prod Inc |
Treatment of insulin resistance syndrome and type 2 diabetes with pde9 inhibitors
|
TW200303201A
(en)
|
2001-12-10 |
2003-09-01 |
Bristol Myers Squibb Co |
Synthesis of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones
|
US7166293B2
(en)
|
2002-03-29 |
2007-01-23 |
Carlsbad Technology, Inc. |
Angiogenesis inhibitors
|
US20050119278A1
(en)
|
2002-05-16 |
2005-06-02 |
Che-Ming Teng |
Anti-angiogenesis methods
|
TW200406385A
(en)
|
2002-05-31 |
2004-05-01 |
Eisai Co Ltd |
Pyrazole compound and pharmaceutical composition containing the same
|
JP4909068B2
(ja)
|
2003-02-14 |
2012-04-04 |
グラクソ グループ リミテッド |
カルボキサミド誘導体
|
MXPA05008441A
(es)
|
2003-02-14 |
2005-10-19 |
Wyeth Corp |
Derivados de heterociclil-3-sulfonilindazol o azaindazol como ligandos de 5-hidroxitriptamina-6.
|
WO2004087906A1
(en)
|
2003-03-31 |
2004-10-14 |
Pfizer Products Inc. |
Crystal structure of 3',5'-cyclic nucleotide phosphodiesterase 1b (pde1b) and uses thereof
|
EP1620437B1
(en)
|
2003-04-29 |
2009-06-17 |
Pfizer Limited |
5,7-diaminopyrazolo¬4,3-d pyrimidines useful in the traetment of hypertension
|
EP1628661A2
(en)
|
2003-06-05 |
2006-03-01 |
Vertex Pharmaceuticals Incorporated |
Modulators of vr1 receptor
|
US7183267B2
(en)
|
2003-06-10 |
2007-02-27 |
The Johns Hopkins University |
β-lactamase inhibitors and methods of use thereof
|
JP2007500700A
(ja)
|
2003-07-29 |
2007-01-18 |
スミスクライン ビーチャム コーポレーション |
化合物
|
TWI339206B
(en)
|
2003-09-04 |
2011-03-21 |
Vertex Pharma |
Compositions useful as inhibitors of protein kinases
|
JP4768628B2
(ja)
|
2003-11-19 |
2011-09-07 |
アレイ バイオファーマ、インコーポレイテッド |
Mekの二環系阻害剤及びその使用方法
|
US7241773B2
(en)
|
2003-12-22 |
2007-07-10 |
Abbott Laboratories |
3-quinuclidinyl heteroatom bridged biaryl derivatives
|
US20050137398A1
(en)
|
2003-12-22 |
2005-06-23 |
Jianguo Ji |
3-Quinuclidinyl heteroatom bridged biaryl derivatives
|
GB0402137D0
(en)
|
2004-01-30 |
2004-03-03 |
Smithkline Beecham Corp |
Novel compounds
|
DE102004005172A1
(de)
|
2004-02-02 |
2005-08-18 |
Aventis Pharma Deutschland Gmbh |
Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
|
WO2005085249A1
(en)
|
2004-02-27 |
2005-09-15 |
F. Hoffmann-La Roche Ag |
Fused derivatives of pyrazole
|
AU2005219517A1
(en)
|
2004-02-27 |
2005-09-15 |
F.Hoffmann-La Roche Ag |
Heteroaryl-fused pyrazolo derivatives
|
US20070185152A1
(en)
|
2004-03-02 |
2007-08-09 |
Smithkline Beecham Corporation |
Inhibitors of akt activity
|
TW200618800A
(en)
|
2004-08-03 |
2006-06-16 |
Uriach Y Compania S A J |
Heterocyclic compounds
|
MX2007002584A
(es)
|
2004-09-02 |
2007-09-07 |
Genentech Inc |
Inhibidores de piridilo de senalizacion de hedgehog.
|
WO2006038001A1
(en)
|
2004-10-06 |
2006-04-13 |
Celltech R & D Limited |
Aminopyrimidine derivatives as jnk inhibitors
|
EP1838296B1
(en)
|
2004-10-20 |
2012-08-08 |
Resverlogix Corp. |
Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases
|
AR051596A1
(es)
|
2004-10-26 |
2007-01-24 |
Irm Llc |
Compuestos heterociclicos condensados nitrogenados como inhibidores de la actividad del receptor canabinoide 1; composiciones farmaceuticas que los contienen y su empleo en la preparacion de medicamentos para el tratamiento de trastornos alimentarios
|
EP1805136A1
(en)
|
2004-10-28 |
2007-07-11 |
The Institutes for Pharmaceutical Discovery, LLC |
Substituted phenylalkanoic acids
|
WO2006053109A1
(en)
|
2004-11-10 |
2006-05-18 |
Synta Pharmaceuticals Corp. |
Heteroaryl compounds
|
MX2007005643A
(es)
|
2004-11-10 |
2008-03-13 |
Cgi Pharmaceuticals Inc |
Ciertas imidazo [1,2-a] pirazin-8-ilaminas, metodo para su elaboracion y metodo de uso de las mismas.
|
AU2005304393B2
(en)
|
2004-11-10 |
2012-09-27 |
Synta Pharmaceuticals Corp. |
IL-12 modulatory compounds
|
DE102004054666A1
(de)
|
2004-11-12 |
2006-05-18 |
Bayer Cropscience Gmbh |
Substituierte Pyrazol-3-carboxamide, Verfahren zur Herstellung und Verwendung als Herbizide und Pflanzenwachstumsregulatoren
|
CN100516049C
(zh)
|
2004-11-16 |
2009-07-22 |
永信药品工业股份有限公司 |
抗血管生成药n2-(取代的芳基甲基)-3-(取代的苯基)吲唑的合成
|
JP5038905B2
(ja)
|
2005-01-07 |
2012-10-03 |
エモリー・ユニバーシテイ |
医学的障害の治療用のcxcr4拮抗薬
|
JP5023054B2
(ja)
|
2005-03-31 |
2012-09-12 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
抗バクテリア剤としての二環式ピラゾール化合物
|
US20070032493A1
(en)
|
2005-05-26 |
2007-02-08 |
Synta Pharmaceuticals Corp. |
Method for treating B cell regulated autoimmune disorders
|
EP1910369A1
(en)
|
2005-07-29 |
2008-04-16 |
Astellas Pharma Inc. |
Fused heterocycles as lck inhibitors
|
US20070037865A1
(en)
|
2005-08-04 |
2007-02-15 |
Sirtris Pharmaceuticals, Inc. |
Sirtuin modulating compounds
|
GB0516703D0
(en)
|
2005-08-15 |
2005-09-21 |
Syngenta Participations Ag |
Novel insecticides
|
JP2007055940A
(ja)
|
2005-08-24 |
2007-03-08 |
Astellas Pharma Inc |
ピラゾロピリミジン誘導体
|
JP2009506007A
(ja)
|
2005-08-25 |
2009-02-12 |
エフ.ホフマン−ラ ロシュ アーゲー |
p38MAPキナーゼ阻害剤及びその使用方法
|
AU2006283944A1
(en)
|
2005-08-25 |
2007-03-01 |
F. Hoffmann-La Roche Ag |
P38 MAP kinase inhibitors and methods for using the same
|
BRPI0614884A2
(pt)
|
2005-08-25 |
2011-04-19 |
Hoffmann La Roche |
inibidores de p38 map cinase e métodos para uso dos mesmos
|
WO2007030582A2
(en)
|
2005-09-09 |
2007-03-15 |
Bristol-Myers Squibb Company |
Acyclic ikur inhibitors
|
US20070087988A1
(en)
|
2005-09-30 |
2007-04-19 |
New York University |
Hematopoietic progenitor kinase 1 for modulation of an immune response
|
US20080242685A1
(en)
|
2005-10-25 |
2008-10-02 |
Smithkline Beecham Corporation |
Chemical Compounds
|
AU2006311766A1
(en)
|
2005-11-03 |
2007-05-18 |
Ilypsa, Inc. |
Indole compounds having C4-acidic substituents and use thereof as phospholipase-A2 inhibitors
|
RU2008126228A
(ru)
|
2005-11-30 |
2010-01-10 |
Астеллас Фарма Инк. (Jp) |
2-аминобензамидное производное
|
GB0525143D0
(en)
|
2005-12-09 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
CA2635997A1
(en)
|
2006-01-11 |
2007-07-19 |
Astrazeneca Ab |
Morpholino pyrimidine derivatives and their use in therapy
|
CN101426779B
(zh)
|
2006-02-16 |
2013-08-21 |
先正达参股股份有限公司 |
含有二环双酰胺结构的农药
|
WO2007112093A2
(en)
|
2006-03-23 |
2007-10-04 |
Synta Pharmaceuticals Corp. |
Benzimidazolyl-pyridine compounds for inflammation and immune-related uses
|
PL1999132T3
(pl)
|
2006-03-30 |
2012-12-31 |
Irm Llc |
Azolopirymidyny jako inhibitory aktywności Receptora Kannabinoidowego typu 1
|
PL2018380T3
(pl)
|
2006-05-19 |
2012-05-31 |
Abbvie Bahamas Ltd |
Skondensowane azabicykliczne pochodne alkanowe podstawione bicykloheterocyklem o aktywności wobec OUN
|
US20080280891A1
(en)
|
2006-06-27 |
2008-11-13 |
Locus Pharmaceuticals, Inc. |
Anti-cancer agents and uses thereof
|
WO2008008059A1
(en)
|
2006-07-12 |
2008-01-17 |
Locus Pharmaceuticals, Inc. |
Anti-cancer agents ans uses thereof
|
PE20121506A1
(es)
|
2006-07-14 |
2012-11-26 |
Amgen Inc |
Compuestos triazolopiridinas como inhibidores de c-met
|
GB0614691D0
(en)
|
2006-07-24 |
2006-08-30 |
Syngenta Participations Ag |
Insecticidal compounds
|
BRPI0717805A2
(pt)
|
2006-10-06 |
2013-10-29 |
Irm Llc |
Inibidores de proteína quinase e métodos de uso dos mesmos
|
AU2007329728A1
(en)
|
2006-10-20 |
2008-06-12 |
Concert Pharmaceuticals Inc. |
3-(dihydro-1H-pyrazolo (4,3-d) pyrimidin-5-yl)-4-propoxybenzenesulfonamide derivatives and methods of use
|
WO2008089310A2
(en)
|
2007-01-18 |
2008-07-24 |
Lexicon Pharmaceuticals, Inc. |
Delta 5 desaturase inhibitors for the treatment of obesity
|
WO2008089307A2
(en)
|
2007-01-18 |
2008-07-24 |
Lexicon Pharmaceuticals, Inc. |
Delta 5 desaturase inhibitors for the treatment of pain, inflammation and cancer
|
JP5330274B2
(ja)
*
|
2007-03-01 |
2013-10-30 |
ノバルティス アーゲー |
Pimキナーゼ阻害剤およびその使用方法
|
US20140249135A1
(en)
*
|
2007-03-01 |
2014-09-04 |
Novartis Ag |
Pim kinase inhibitors and methods of their use
|
EP2002835A1
(en)
|
2007-06-04 |
2008-12-17 |
GenKyo Tex |
Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
|
TW200916472A
(en)
*
|
2007-06-20 |
2009-04-16 |
Sirtris Pharmaceuticals Inc |
Sirtuin modulating compounds
|
BRPI0814441A2
(pt)
*
|
2007-07-19 |
2015-07-14 |
Schering Corp |
Compostos de amida heterocíclica como inibidores de proteína cinase
|
MY146643A
(en)
|
2007-07-30 |
2012-09-14 |
Dae Woong Pharma |
Novel benzoimidazole derivatives and pharmaceutical composition comprising the same
|
BRPI0814975A2
(pt)
|
2007-08-08 |
2015-02-03 |
Merck Serono Sa |
Derivados de 6-amino-pirimidina-4-carboxamida e compostos relacionados que se ligam ao receptor de 1-fosfato de esfingosina (s1p) para o tratamento de esclerose múltipla
|
GB0716414D0
(en)
|
2007-08-22 |
2007-10-03 |
Syngenta Participations Ag |
Novel insecticides
|
WO2009032651A1
(en)
|
2007-08-31 |
2009-03-12 |
Smithkline Beecham Corporation |
Inhibitors of akt activity
|
WO2009038784A1
(en)
|
2007-09-21 |
2009-03-26 |
Amgen Inc. |
Triazole fused heteroaryl compounds as p38 kinase inhibitors
|
KR20100092000A
(ko)
|
2007-11-01 |
2010-08-19 |
서트리스 파마슈티컬즈, 인코포레이티드 |
시르투인 조절제로서의 아미드 유도체
|
KR100963644B1
(ko)
|
2007-11-23 |
2010-06-15 |
한국과학기술연구원 |
피라졸로피리미딘온 유도체 및 그의 제조방법
|
BRPI0905952A2
(pt)
|
2008-02-04 |
2015-06-30 |
Mercury Therapeutics |
Composto e sais do mesmo e compição farmacêutica
|
CN102098918A
(zh)
|
2008-05-13 |
2011-06-15 |
帕纳德制药公司 |
用于治疗癌症和神经退行性疾病的生物活性化合物
|
CN102089278A
(zh)
|
2008-06-11 |
2011-06-08 |
Irm责任有限公司 |
用于治疗疟疾的化合物和组合物
|
KR101892989B1
(ko)
|
2008-06-27 |
2018-08-30 |
셀젠 카르 엘엘씨 |
헤테로아릴 화합물 및 이의 용도
|
US20110294853A1
(en)
|
2008-09-12 |
2011-12-01 |
Benjamin Pelcman |
Bis Aromatic Compounds for Use in the Treatment of Inflammation
|
EP2165707A1
(en)
|
2008-09-23 |
2010-03-24 |
Genkyo Tex Sa |
Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
|
EP2166008A1
(en)
|
2008-09-23 |
2010-03-24 |
Genkyo Tex Sa |
Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
|
EP2166010A1
(en)
|
2008-09-23 |
2010-03-24 |
Genkyo Tex Sa |
Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
|
WO2010046780A2
(en)
|
2008-10-22 |
2010-04-29 |
Institut Pasteur Korea |
Anti viral compounds
|
JP2010111624A
(ja)
|
2008-11-06 |
2010-05-20 |
Shionogi & Co Ltd |
Ttk阻害作用を有するインダゾール誘導体
|
JP5770102B2
(ja)
|
2008-12-19 |
2015-08-26 |
ジェネンテック, インコーポレイテッド |
複素環化合物と使用方法
|
KR20100101056A
(ko)
|
2009-03-07 |
2010-09-16 |
주식회사 메디젠텍 |
세포핵에서 세포질로의 gsk3의 이동을 억제하는 화합물을 함유하는 세포핵에서 세포질로의 gsk3 이동에 의해 발생되는 질환의 치료 또는 예방용 약학적 조성물
|
EP2408744A1
(en)
|
2009-03-18 |
2012-01-25 |
Schering Corporation |
Bicyclic compounds as inhibitors of diacylglycerol acyltransferase
|
US9051185B2
(en)
|
2009-03-26 |
2015-06-09 |
Northeastern University |
Carbon nanostructures from pyrolysis of organic materials
|
WO2010118367A2
(en)
|
2009-04-10 |
2010-10-14 |
Progenics Pharmaceuticals, Inc. |
Antiviral pyrimidines
|
EP2789615B1
(en)
|
2009-08-11 |
2017-05-03 |
Bristol-Myers Squibb Company |
Azaindazoles as Btk kinase modulators and use thereof
|
US20120172369A1
(en)
|
2009-09-14 |
2012-07-05 |
Ting Pauline C |
Inhibitors of diacylglycerol acyltransferase
|
WO2011050245A1
(en)
|
2009-10-23 |
2011-04-28 |
Yangbo Feng |
Bicyclic heteroaryls as kinase inhibitors
|
ES2360333B1
(es)
|
2009-10-29 |
2012-05-04 |
Consejo Superior De Investigaciones Cientificas (Csic) (70%) |
Derivados de bis (aralquil) amino y sistemas (hetero) aromaticos de seis miembros y su uso en el tratamiento de patologias neurodegenerativas, incluida la enfermedad de alzheimer
|
JP2013032290A
(ja)
|
2009-11-20 |
2013-02-14 |
Dainippon Sumitomo Pharma Co Ltd |
新規縮合ピリミジン誘導体
|
WO2011078143A1
(ja)
|
2009-12-22 |
2011-06-30 |
塩野義製薬株式会社 |
ピリミジン誘導体およびそれらを含有する医薬組成物
|
CA2784807C
(en)
|
2009-12-29 |
2021-12-14 |
Dana-Farber Cancer Institute, Inc. |
Type ii raf kinase inhibitors
|
WO2011082400A2
(en)
|
2010-01-04 |
2011-07-07 |
President And Fellows Of Harvard College |
Modulators of immunoinhibitory receptor pd-1, and methods of use thereof
|
WO2011082488A1
(en)
|
2010-01-06 |
2011-07-14 |
British Columbia Cancer Agency Branch |
Bisphenol derivative therapeutics and methods for their use
|
DE102010009903A1
(de)
|
2010-03-02 |
2011-09-08 |
Merck Patent Gmbh |
Verbindungen für elektronische Vorrichtungen
|
CN102206172B
(zh)
|
2010-03-30 |
2015-02-25 |
中国医学科学院医药生物技术研究所 |
一组取代双芳基化合物及其制备方法和抗病毒应用
|
US9133123B2
(en)
|
2010-04-23 |
2015-09-15 |
Cytokinetics, Inc. |
Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
|
PL2563776T3
(pl)
|
2010-04-27 |
2017-01-31 |
Calcimedica Inc |
Związki, które modulują wewnątrzkomórkowy wapń
|
GB201008134D0
(en)
|
2010-05-14 |
2010-06-30 |
Medical Res Council Technology |
Compounds
|
JP2011246389A
(ja)
|
2010-05-26 |
2011-12-08 |
Oncotherapy Science Ltd |
Ttk阻害作用を有する縮環ピラゾール誘導体
|
EP2576539B1
(de)
|
2010-05-27 |
2017-12-13 |
Bayer CropScience AG |
Pyridinylcarbonsäure derivate als fungizide
|
WO2011153553A2
(en)
|
2010-06-04 |
2011-12-08 |
The Regents Of The University Of California |
Methods and compositions for kinase inhibition
|
JP5993846B2
(ja)
|
2010-06-15 |
2016-09-14 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH |
アントラニル酸誘導体
|
WO2011158108A2
(en)
|
2010-06-16 |
2011-12-22 |
Purdue Pharma L.P. |
Aryl substituted indoles and the use thereof
|
JP5926727B2
(ja)
|
2010-07-28 |
2016-05-25 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH |
置換イミダゾ[1,2−b]ピリダジン
|
JP5844376B2
(ja)
|
2010-10-06 |
2016-01-13 |
ジェイファーマ株式会社 |
強力な尿酸トランスポーター阻害剤の開発:それらの尿酸排泄効果のために設計された化合物
|
GB201017345D0
(en)
|
2010-10-14 |
2010-11-24 |
Proximagen Ltd |
Receptor antagonists
|
EP2796456A1
(en)
|
2010-12-09 |
2014-10-29 |
Amgen Inc. |
Bicyclic compounds as Pim inhibitors
|
AR084308A1
(es)
|
2010-12-17 |
2013-05-08 |
Syngenta Participations Ag |
Compuestos insecticidas derivados de triazol
|
EP2661433B1
(en)
|
2011-01-04 |
2017-08-16 |
Novartis AG |
Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (amd)
|
ES2732311T3
(es)
|
2011-02-07 |
2019-11-21 |
Univ Washington |
Compuestos de manósidos y procedimientos de uso de los mismos
|
ES2588680T3
(es)
|
2011-03-28 |
2016-11-04 |
F. Hoffmann-La Roche Ag |
Compuestos de tiazolopirimidina
|
AU2012243583B2
(en)
|
2011-04-12 |
2015-10-22 |
Chong Kun Dang Pharmaceutical Corp. |
Cycloalkenyl aryl derivatives for CETP inhibitor
|
PE20140928A1
(es)
|
2011-04-21 |
2014-08-24 |
Origenis Gmbh |
Pirazolo[4,3-d]pirimidinas utiles como inhibidores de cinasas
|
WO2012151567A1
(en)
*
|
2011-05-05 |
2012-11-08 |
St. Jude Children's Research Hospital |
Pyrimidinone compounds and methods for preventing and treating influenza
|
US20140107151A1
(en)
|
2011-05-17 |
2014-04-17 |
Principia Biophama Inc. |
Tyrosine kinase inhibitors
|
EP2710004A1
(en)
|
2011-05-17 |
2014-03-26 |
Bayer Intellectual Property GmbH |
Amino-substituted imidazopyridazines as mknk1 kinase inhibitors
|
TW201311677A
(zh)
|
2011-05-31 |
2013-03-16 |
Syngenta Participations Ag |
殺蟲化合物
|
JP6073868B2
(ja)
|
2011-06-01 |
2017-02-01 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH |
置換アミノイミダゾピリダジン
|
JP5944497B2
(ja)
|
2011-06-22 |
2016-07-05 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH |
ヘテロシクリルアミノイミダゾピリダジン
|
EP2543372A1
(en)
|
2011-07-08 |
2013-01-09 |
Helmholtz-Zentrum für Infektionsforschung GmbH |
Medicament for the treatment of liver cancer
|
WO2013007708A1
(en)
|
2011-07-08 |
2013-01-17 |
Helmholtz-Zentrum für Infektionsforschung GmbH |
Medicament for treatment of liver cancer
|
US9394293B2
(en)
|
2011-08-10 |
2016-07-19 |
Purdue Pharma L.P. |
TRPV1 antagonists including dihydroxy substituent and uses thereof
|
EP2742040B1
(en)
|
2011-08-12 |
2016-04-06 |
F.Hoffmann-La Roche Ag |
Indazole compounds, compositions and methods of use
|
CA2838784A1
(en)
|
2011-08-12 |
2013-02-21 |
F. Hoffmann-La Roche Ag |
Pyrazolo[3,4-c]pyridine compounds and methods of use
|
WO2013042137A1
(en)
|
2011-09-19 |
2013-03-28 |
Aurigene Discovery Technologies Limited |
Bicyclic heterocycles as irak4 inhibitors
|
CN103814029B
(zh)
|
2011-09-23 |
2016-10-12 |
拜耳知识产权有限责任公司 |
取代的咪唑并哒嗪
|
CN102516263B
(zh)
|
2011-10-25 |
2015-04-08 |
南方医科大学 |
一种螺三环类化合物及其制备方法、以及含该类化合物的药物组合物及其应用
|
CN102503959B
(zh)
|
2011-10-25 |
2015-04-08 |
南方医科大学 |
一种稠三环类化合物及其制备方法、以及含该类化合物的药物组合物及其应用
|
KR20140095513A
(ko)
|
2011-11-01 |
2014-08-01 |
에프. 호프만-라 로슈 아게 |
이미다조피리다진 화합물
|
JP6200903B2
(ja)
|
2012-02-17 |
2017-09-20 |
キネタ フォー エルエルシー |
アレナウイルス感染症の治療のための抗ウイルス薬
|
TW201348231A
(zh)
|
2012-02-29 |
2013-12-01 |
Amgen Inc |
雜雙環化合物
|
IN2014MN01897A
(es)
|
2012-03-09 |
2015-07-10 |
Carna Biosciences Inc |
|
JP6101248B2
(ja)
|
2012-03-28 |
2017-03-22 |
出光興産株式会社 |
新規化合物、有機エレクトロルミネッセンス素子用材料および有機エレクトロルミネッセンス素子
|
NZ622769A
(en)
|
2012-04-20 |
2017-06-30 |
Gilead Sciences Inc |
Benzothiazol-6-yl acetic acid derivatives and their use for treating an hiv infection
|
WO2014003405A1
(ko)
|
2012-06-26 |
2014-01-03 |
주식회사 제이앤드제이 캐미칼 |
신규한 화합물 및 이를 포함하는 발광소자
|
MX2014015738A
(es)
|
2012-06-28 |
2015-08-06 |
Novartis Ag |
Derivados de pirrolidina y su uso como moduladores de la senda del complemento.
|
KR101936851B1
(ko)
|
2012-07-16 |
2019-01-11 |
한국과학기술연구원 |
단백질 키나아제 저해제인 신규 피라졸로피리딘 유도체 또는 인다졸 유도체
|
WO2014024125A1
(en)
|
2012-08-08 |
2014-02-13 |
Celon Pharma S.A. |
Pyrazolo[4,3-d]pyrimidin-7(6h)-one derivatives as pde9 inhibitors
|
BR112015003380A2
(pt)
|
2012-08-23 |
2017-07-04 |
Mitsubishi Tanabe Pharma Corp |
composto de pirazolopirimidina
|
US9882150B2
(en)
|
2012-09-24 |
2018-01-30 |
Arizona Board Of Regents For And On Behalf Of Arizona State University |
Metal compounds, methods, and uses thereof
|
CN104837832B
(zh)
|
2012-10-05 |
2019-04-26 |
里格尔药品股份有限公司 |
Gdf-8抑制剂
|
KR102137472B1
(ko)
|
2013-02-08 |
2020-07-27 |
삼성디스플레이 주식회사 |
유기 발광 소자
|
US9242969B2
(en)
|
2013-03-14 |
2016-01-26 |
Novartis Ag |
Biaryl amide compounds as kinase inhibitors
|
US10273243B2
(en)
|
2013-03-14 |
2019-04-30 |
The Trustees Of Columbia University In The City Of New York |
4-phenylpiperidines, their preparation and use
|
US9227978B2
(en)
|
2013-03-15 |
2016-01-05 |
Araxes Pharma Llc |
Covalent inhibitors of Kras G12C
|
US9034927B2
(en)
|
2013-05-22 |
2015-05-19 |
Curza Global, Llc |
Methods of use for compositions comprising a biocidal polyamine
|
JP6603445B2
(ja)
|
2013-06-10 |
2019-11-06 |
アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・アリゾナ・ステイト・ユニバーシティー |
改変された発光スペクトルを有する蛍光性四座配位金属錯体
|
EP3035800B1
(en)
|
2013-08-22 |
2019-10-09 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
TWI652014B
(zh)
|
2013-09-13 |
2019-03-01 |
美商艾佛艾姆希公司 |
雜環取代之雙環唑殺蟲劑
|
WO2015037965A1
(en)
|
2013-09-16 |
2015-03-19 |
Rohm And Haas Electronic Materials Korea Ltd. |
Novel organic electroluminescent compounds and organic electroluminescent device comprising the same
|
EP3057954A2
(en)
|
2013-10-18 |
2016-08-24 |
Syros Pharmaceuticals, Inc. |
Heteromaromatic compounds useful for the treatment of proliferative diseases
|
WO2015061247A2
(en)
|
2013-10-21 |
2015-04-30 |
Merck Patent Gmbh |
Heteroaryl compounds as btk inhibitors and uses thereof
|
EP3080122B1
(en)
|
2013-12-11 |
2018-10-31 |
Biogen MA Inc. |
Biaryl compounds useful for the treatment of human diseases in oncology, neurology and immunology
|
EP3079683A4
(en)
|
2013-12-13 |
2017-12-20 |
Dana-Farber Cancer Institute, Inc. |
Methods to treat lymphoplasmacytic lymphoma
|
TWI667233B
(zh)
|
2013-12-19 |
2019-08-01 |
德商拜耳製藥公司 |
新穎吲唑羧醯胺,其製備方法、含彼等之醫藥製劑及其製造醫藥之用途
|
US9714232B2
(en)
|
2013-12-20 |
2017-07-25 |
Sunshine Lake Pharma Co., Ltd. |
Substituted piperazine compounds and methods of use thereof
|
BR112016015983A2
(pt)
|
2014-01-10 |
2017-08-08 |
Aurigene Discovery Tech Ltd |
Compostos de indazol como inibidores de irak4, seus usos, e composição farmacêutica
|
JP6640098B2
(ja)
|
2014-02-05 |
2020-02-05 |
メルク、パテント、ゲゼルシャフト、ミット、ベシュレンクテル、ハフツングMerck Patent GmbH |
金属錯体
|
JP6537532B2
(ja)
|
2014-02-25 |
2019-07-03 |
アキリオン ファーマシューティカルズ,インコーポレーテッド |
補体媒介障害の治療のための化合物
|
US9871208B2
(en)
|
2014-02-26 |
2018-01-16 |
Samsung Display Co., Ltd. |
Condensed cyclic compound and organic light-emitting device including the same
|
WO2015164956A1
(en)
|
2014-04-29 |
2015-11-05 |
The University Of British Columbia |
Benzisothiazole derivative compounds as therapeutics and methods for their use
|
US20150328188A1
(en)
|
2014-05-19 |
2015-11-19 |
Everardus O. Orlemans |
Combination Therapies for the Treatment of Proliferative Disorders
|
US11107994B2
(en)
|
2014-06-18 |
2021-08-31 |
Merck Patent Gmbh |
Materials for organic electroluminescent devices
|
EP3157521A4
(en)
|
2014-06-20 |
2018-02-14 |
Aurigene Discovery Technologies Limited |
Substituted indazole compounds as irak4 inhibitors
|
CN107027307B
(zh)
|
2014-06-20 |
2020-12-22 |
韩国巴斯德研究所 |
一种抗感染化合物
|
US20170247366A1
(en)
|
2014-06-25 |
2017-08-31 |
Vanderbilt University |
Substituted 4-alkoxypicolinamide analogs as mglur5 negative allosteric modulators and methods of making and using the same
|
KR20160007967A
(ko)
|
2014-07-10 |
2016-01-21 |
삼성디스플레이 주식회사 |
유기 발광 소자
|
WO2016040181A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
WO2016040180A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
WO2016040184A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
WO2016040188A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
WO2016041618A1
(en)
|
2014-09-15 |
2016-03-24 |
Merck Patent Gmbh |
Substituted indazoles and related heterocycles
|
MX2017004200A
(es)
|
2014-10-06 |
2017-06-15 |
Merck Patent Gmbh |
Compuestos de heteroarilo como inhibidores de tirosina-cinasa de bruton (btk) y usos de estos.
|
JO3705B1
(ar)
|
2014-11-26 |
2021-01-31 |
Bayer Pharma AG |
إندازولات مستبدلة جديدة، عمليات لتحضيرها، مستحضرات دوائية تحتوي عليها واستخدامها في إنتاج أدوية
|
EP3227337A1
(en)
|
2014-12-05 |
2017-10-11 |
F. Hoffmann-La Roche AG |
Methods and compositions for treating cancer using pd-1 axis antagonists and hpk1 antagonists
|
EP3254317B1
(de)
|
2015-02-03 |
2019-07-31 |
Merck Patent GmbH |
Metallkomplexe
|
ES2872553T3
(es)
|
2015-03-06 |
2021-11-02 |
Pharmakea Inc |
Inhibidores de lisil oxidasa tipo-2 y usos de los mismos
|
CN112608300B
(zh)
|
2015-03-11 |
2024-04-26 |
Fmc公司 |
杂环取代的二环唑杀有害生物剂
|
WO2016161571A1
(en)
|
2015-04-08 |
2016-10-13 |
Merck Sharp & Dohme Corp. |
Indazole and azaindazole btk inhibitors
|
JP6847855B2
(ja)
|
2015-04-30 |
2021-03-24 |
バイエル ファーマ アクチエンゲゼルシャフト |
Irak4の阻害剤とbtkの阻害剤の組み合わせ
|
BR112017027241B1
(pt)
|
2015-06-25 |
2023-09-26 |
University Health Network |
Inibidores de hpk1 e composição farmacêutica
|
AU2016293441A1
(en)
|
2015-07-15 |
2018-02-01 |
Aurigene Discovery Technologies Limited |
Indazole and azaindazole compounds as IRAK-4 inhibitors
|
AU2016293446A1
(en)
|
2015-07-15 |
2018-02-15 |
Aurigene Discovery Technologies Limited |
Substituted aza compounds as IRAK-4 inhibitors
|
EP3331530A4
(en)
|
2015-08-03 |
2018-12-19 |
Raze Therapeutics Inc. |
Mthfd2 inhibitors and uses thereof
|
WO2017023972A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
|
WO2017027400A1
(en)
|
2015-08-07 |
2017-02-16 |
Calcimedica, Inc. |
Use of crac channel inhibitors for the treatment of stroke and traumatic brain injury
|
WO2017045955A1
(en)
|
2015-09-14 |
2017-03-23 |
Basf Se |
Heterobicyclic compounds
|
WO2017058915A1
(en)
|
2015-09-28 |
2017-04-06 |
Araxes Pharma Llc |
Inhibitors of kras g12c mutant proteins
|
WO2017108744A1
(de)
|
2015-12-22 |
2017-06-29 |
Bayer Pharma Aktiengesellschaft |
Neue substituierte indazole, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln
|
KR20180105161A
(ko)
|
2016-01-07 |
2018-09-27 |
씨에스 파마테크 리미티드 |
Egfr 티로신 키나제의 임상적으로 중요한 돌연변이체의 선택적 억제제
|
US20190262126A1
(en)
|
2016-07-19 |
2019-08-29 |
Arthur Bernard CUMMINGS |
Artificial accommodating lens complex
|
CN110818690B
(zh)
|
2016-07-26 |
2021-08-10 |
深圳市塔吉瑞生物医药有限公司 |
用于抑制蛋白酪氨酸激酶活性的氨基嘧啶类化合物
|
US20180072718A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridine compounds and uses thereof
|
WO2018049191A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridone derivatives as hpk1 modulators and uses thereof for the treatment of cancer
|
AR109595A1
(es)
*
|
2016-09-09 |
2018-12-26 |
Incyte Corp |
Compuestos de pirazolopirimidina y usos de estos como inhibidores de hpk1
|
CN109923114B
(zh)
|
2016-09-09 |
2022-11-01 |
因赛特公司 |
作为hpk1调节剂的吡唑并吡啶衍生物和其用于治疗癌症的用途
|
US20180228786A1
(en)
|
2017-02-15 |
2018-08-16 |
Incyte Corporation |
Pyrazolopyridine compounds and uses thereof
|
US10722495B2
(en)
|
2017-09-08 |
2020-07-28 |
Incyte Corporation |
Cyanoindazole compounds and uses thereof
|
US10752635B2
(en)
|
2018-02-20 |
2020-08-25 |
Incyte Corporation |
Indazole compounds and uses thereof
|
US10745388B2
(en)
|
2018-02-20 |
2020-08-18 |
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