MX2021007540A - Derivados biciclicos. - Google Patents

Derivados biciclicos.

Info

Publication number
MX2021007540A
MX2021007540A MX2021007540A MX2021007540A MX2021007540A MX 2021007540 A MX2021007540 A MX 2021007540A MX 2021007540 A MX2021007540 A MX 2021007540A MX 2021007540 A MX2021007540 A MX 2021007540A MX 2021007540 A MX2021007540 A MX 2021007540A
Authority
MX
Mexico
Prior art keywords
bicyclic derivatives
bicyclic
derivatives
endoparasites
warm
Prior art date
Application number
MX2021007540A
Other languages
English (en)
Inventor
Chouaib Tahtaoui
Francois Pautrat
Pierre Ducray
Denise Rageot
Original Assignee
Elanco Tiergesundheit Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elanco Tiergesundheit Ag filed Critical Elanco Tiergesundheit Ag
Publication of MX2021007540A publication Critical patent/MX2021007540A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención proporciona compuestos de fórmula (I): (ver Fórmula) (I) que son útiles en el control de endoparásitos, por ejemplo, gusanos del corazón, en animales de sangre caliente.
MX2021007540A 2018-12-18 2019-12-13 Derivados biciclicos. MX2021007540A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862781132P 2018-12-18 2018-12-18
PCT/US2019/066302 WO2020131631A1 (en) 2018-12-18 2019-12-13 Bicyclic derivatives

Publications (1)

Publication Number Publication Date
MX2021007540A true MX2021007540A (es) 2021-10-13

Family

ID=69143705

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021007540A MX2021007540A (es) 2018-12-18 2019-12-13 Derivados biciclicos.

Country Status (10)

Country Link
US (1) US20220064159A1 (es)
EP (1) EP3897842A1 (es)
JP (1) JP7324846B2 (es)
CN (1) CN113490527A (es)
AR (1) AR116908A1 (es)
AU (1) AU2019405444B2 (es)
BR (1) BR112021012021A2 (es)
CA (1) CA3122106A1 (es)
MX (1) MX2021007540A (es)
WO (1) WO2020131631A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3941587A1 (en) 2019-03-19 2022-01-26 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
CN114206860A (zh) * 2019-06-07 2022-03-18 礼蓝动物保健有限公司 用于治疗体内寄生虫的双环衍生物
BR112022012126A2 (pt) * 2019-12-18 2022-08-30 Intervet Int Bv Compostos antelmínticos compreendendo uma estrutura quinolínica
MX2022012652A (es) * 2020-04-09 2022-11-10 Bayer Animal Health Gmbh Nuevos compuestos antihelminticos.
MX2022015038A (es) 2020-05-29 2023-01-04 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos como anthelminticos.
JP2023553269A (ja) 2020-11-18 2023-12-21 エランコ・ティアゲゾンタイト・アーゲー イヌ糸状虫感染症を治療するためのｎ－（２，３－ジヒドロ－１，４－ベンゾオキサジン－４－イル）－３－イソプロピル－７－（２，３，５－トリフルオロフェニル）ベンゾ－チオフェン－２－カルボキサミド誘導体及び類似化合物
TW202237600A (zh) 2020-12-04 2022-10-01 瑞士商禮藍動物保健股份有限公司 雙環衍生物
KR20230146012A (ko) * 2021-02-09 2023-10-18 셀진 코포레이션 연충 감염 및 질병의 치료를 위한 설폰아미드 및 이들의용도
EP4148052A1 (en) * 2021-09-09 2023-03-15 Bayer Animal Health GmbH New quinoline derivatives
CA3236894A1 (en) 2021-11-01 2023-05-04 Boehringer Ingelheim Vetmedica Gmbh Anthelmintic pyrrolopyridazine compounds

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904108D0 (sv) 1999-11-15 1999-11-15 New Pharma Research Ab Nya föreningar
WO2008050140A2 (en) 2006-10-27 2008-05-02 Spirogen Limited Compounds for treatment of parasitic infection
AU2008340434B2 (en) 2007-12-21 2014-02-06 Boehringer Ingelheim Animal Health USA Inc. The use of 6-halogeno-[1,2,4]-triazolo-[1,5-a]-pyrimidine compounds for combating pests in and on animals
WO2010045505A1 (en) 2008-10-15 2010-04-22 Anacor Pharmaceuticals, Inc Boron-containing small molecules as anti-protozoal agents
CA3020793C (en) 2016-04-15 2024-05-21 Bayer Animal Health Gmbh Pyrazolopyrimidine derivatives
MY196327A (en) * 2016-11-11 2023-03-24 Bayer Animal Health Gmbh New Anthelmintic Quinoline-3-Carboxamide Derivative
SG11201909243TA (en) 2017-04-27 2019-11-28 Bayer Animal Health Gmbh New bicyclic pyrazole derivatives
CA3068350A1 (en) 2017-06-30 2019-01-03 Bayer Animal Health Gmbh New azaquinoline derivatives
SG11202000266VA (en) 2017-08-04 2020-02-27 Bayer Animal Health Gmbh Quinoline derivatives for treating infections with helminths
MX2020011873A (es) 2018-05-09 2021-01-20 Bayer Animal Health Gmbh Nuevos derivados de quinolina.
EP3643711A1 (en) 2018-10-24 2020-04-29 Bayer Animal Health GmbH New anthelmintic compounds
EP3897843A1 (en) 2018-12-18 2021-10-27 Elanco Tiergesundheit AG Bicyclic derivatives

Also Published As

Publication number Publication date
US20220064159A1 (en) 2022-03-03
EP3897842A1 (en) 2021-10-27
AU2019405444A1 (en) 2021-07-08
WO2020131631A1 (en) 2020-06-25
CN113490527A (zh) 2021-10-08
CA3122106A1 (en) 2020-06-25
AR116908A1 (es) 2021-06-23
AU2019405444B2 (en) 2023-05-18
JP7324846B2 (ja) 2023-08-10
JP2022514015A (ja) 2022-02-09
BR112021012021A2 (pt) 2021-09-21

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