BR112022012126A2 - Compostos antelmínticos compreendendo uma estrutura quinolínica - Google Patents

Compostos antelmínticos compreendendo uma estrutura quinolínica

Info

Publication number
BR112022012126A2
BR112022012126A2 BR112022012126A BR112022012126A BR112022012126A2 BR 112022012126 A2 BR112022012126 A2 BR 112022012126A2 BR 112022012126 A BR112022012126 A BR 112022012126A BR 112022012126 A BR112022012126 A BR 112022012126A BR 112022012126 A2 BR112022012126 A2 BR 112022012126A2
Authority
BR
Brazil
Prior art keywords
compounds
antelminthic
quinoline structure
dirofilaria
quinoline
Prior art date
Application number
BR112022012126A
Other languages
English (en)
Inventor
Berger Michael
Linder Michael
Schneider Carolin
Tanzler Janina
Sondern Ulrich
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of BR112022012126A2 publication Critical patent/BR112022012126A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

COMPOSTOS ANTELMÍNTICOS COMPREENDENDO UMA ESTRUTURA QUINOLÍNICA. A presente invenção se refere a novos compostos antelmínticos. Estes compostos podem, por exemplo, serem usados no tratamento do tipo doença parasitária causada por helmintos, tais como Dirofilaria, em particular Dirofilaria immitis.
BR112022012126A 2019-12-18 2020-12-17 Compostos antelmínticos compreendendo uma estrutura quinolínica BR112022012126A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19217685 2019-12-18
EP20213298 2020-12-11
PCT/EP2020/086666 WO2021122911A1 (en) 2019-12-18 2020-12-17 Anthelmintic compounds comprising a quinoline structure

Publications (1)

Publication Number Publication Date
BR112022012126A2 true BR112022012126A2 (pt) 2022-08-30

Family

ID=74130185

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022012126A BR112022012126A2 (pt) 2019-12-18 2020-12-17 Compostos antelmínticos compreendendo uma estrutura quinolínica

Country Status (9)

Country Link
US (1) US20230148316A1 (pt)
EP (1) EP4077281A1 (pt)
JP (1) JP2023507173A (pt)
CN (1) CN114845994A (pt)
AU (1) AU2020406093A1 (pt)
BR (1) BR112022012126A2 (pt)
CA (1) CA3164098A1 (pt)
MX (1) MX2022007670A (pt)
WO (1) WO2021122911A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20220281A1 (es) 2019-03-19 2022-02-25 Boehringer Ingelheim Animal Health Usa Inc Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos
IL298596A (en) 2020-05-29 2023-01-01 Boehringer Ingelheim Animal Health Usa Inc Heterocyclic anthelmintic compounds
AR127495A1 (es) 2021-11-01 2024-01-31 Boehringer Ingelheim Vetmedica Gmbh Compuestos de pirrolopiridazina como antihelmínticos

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0539588A1 (en) 1990-07-05 1993-05-05 Nippon Soda Co., Ltd. Amine derivative
US5399582A (en) 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents
US5595991A (en) 1995-03-20 1997-01-21 Merck & Co., Inc. Anthelmintic use of nodulisporic acid and analogs thereof
US5962499A (en) 1995-03-20 1999-10-05 Merck & Co., Inc. Nodulisporic acid derivatives
CZ294699B6 (cs) 1995-03-20 2005-02-16 Merck And Co., Inc. Deriváty kyseliny nodulisporové a farmaceutický prostředek s jejich obsahem
US6221894B1 (en) 1995-03-20 2001-04-24 Merck & Co., Inc. Nodulisporic acid derivatives
US5834260A (en) 1996-08-30 1998-11-10 Merck & Co., Inc. Antiparasitic agents
US7361689B2 (en) 2003-12-31 2008-04-22 Schering-Plough Animal Health Corporation Antibacterial 1-(4-mono- and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoroproponals and preparation thereof
EP1699799B1 (en) 2003-12-31 2007-05-16 Schering-Plough Ltd. Control of parasites in animals by the use of imidazo [1,2-b]pyridazine derivatives
MX2007003378A (es) 2004-09-23 2007-05-10 Schering Plough Ltd Control de parasitos en animales mediante el uso de nuevos derivados de trifluorometansulfonanilida oxima eter.
WO2006055565A2 (en) 2004-11-19 2006-05-26 Schering-Plough Ltd. Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1h-pyrrol-2-yl) acrylonitrile derivatives
AR054380A1 (es) 2005-06-09 2007-06-20 Schering Plough Ltd Control de parasitos en animales con derivados de n- ((feniloxi) fenil) -1,1,1-trifluorometansulfonamida y de n-(fenilsulfanil) fenil) -1,1,1-trifluorometansulfonamida
DE102006015470A1 (de) 2006-03-31 2007-10-04 Bayer Cropscience Ag Substituierte Enaminocarbonylverbindungen
US8809268B2 (en) 2008-10-29 2014-08-19 The Regents Of The University Of California Combination therapy to combat helminth resistance
US8007761B2 (en) 2008-12-24 2011-08-30 Praxair Technology, Inc. Carbon dioxide emission reduction method
TWI679197B (zh) 2016-05-05 2019-12-11 瑞士商伊蘭科動物健康公司 雜芳基-1,2,4-三唑及雜芳基-三唑化合物
SI3538512T1 (sl) 2016-11-11 2021-09-30 Bayer Animal Health Gmbh Novi antihelmintični kinolin-3-karboksamidni derivati
EP3634959A1 (en) 2017-08-04 2020-04-15 Bayer Animal Health GmbH Quinoline derivatives for treating infections with helminths
KR20200129128A (ko) 2018-03-08 2020-11-17 바이엘 악티엔게젤샤프트 식물 보호에서 살충제로서의 헤테로아릴-트리아졸 및 헤테로아릴-테트라졸 화합물의 용도
EP3904349B1 (en) 2018-04-12 2023-08-23 Bayer Aktiengesellschaft N-(cyclopropylmethyl)-5-(methylsulfonyl)-n-{1-[1-(pyrimidin-2-yl)-1h-1,2,4-triazol-5-yl]ethyl}heterocyclyl amide derivatives and similar compounds as pesticides
UY38184A (es) 2018-04-17 2019-10-31 Bayer Ag Compuestos heteroarilo-triazol y heteroarilo-tetrazol novedosos como plaguicidas
UA127065C2 (uk) 2018-04-25 2023-03-29 Баєр Акціенгезельшафт Нові гетероарил-триазольні та гетероарил-тетразольні сполуки як пестициди
WO2019215198A1 (en) 2018-05-08 2019-11-14 Syngenta Crop Protection Ag Methods of applying one or more certain heteroaryl-1,2,4-triazole and heteroaryl-tetrazole compounds to control damage on plants, propagation material thereof, and plant derived products
TW202019901A (zh) 2018-09-13 2020-06-01 瑞士商先正達合夥公司 殺有害生物活性唑-醯胺化合物
TW202023386A (zh) 2018-09-13 2020-07-01 瑞士商先正達合夥公司 殺有害生物活性唑-醯胺化合物
UY38394A (es) 2018-10-02 2020-04-30 Syngenta Participations Ag Compuestos de benceno y azina-amida activos como plaguicidas
ES2953567T3 (es) 2018-10-19 2023-11-14 Syngenta Participations Ag Compuestos de azol-amida plaguicidamente activos
CN112955442A (zh) 2018-11-05 2021-06-11 先正达参股股份有限公司 杀有害生物活性的唑-酰胺化合物
EP3897842A1 (en) * 2018-12-18 2021-10-27 Elanco Tiergesundheit AG Bicyclic derivatives
EP3696175A1 (en) 2019-02-18 2020-08-19 Syngenta Crop Protection AG Pesticidally active azole-amide compounds
BR112021018822A2 (pt) 2019-03-22 2021-11-23 Syngenta Crop Prot Ag Derivados de n-[1-(5-bromo-2-pirimidin-2-il-1,2,4-triazol-3-il)etil]-2-ciclopropil-6-(trifluorometil)piridina-4-carboxamida e compostos relacionados como inseticidas
UY38623A (es) 2019-03-29 2020-10-30 Syngenta Crop Protection Ag Compuestos de diazina-amida activos como pesticidas
MX2021012162A (es) 2019-04-05 2021-11-03 Syngenta Crop Protection Ag Compuestos de diazina-amida activos como pesticidas.
CN113677672A (zh) 2019-04-11 2021-11-19 先正达农作物保护股份公司 杀有害生物活性的二嗪-酰胺化合物
EP3725788A1 (en) 2019-04-15 2020-10-21 Bayer AG Novel heteroaryl-substituted aminoalkyl azole compounds as pesticides
CN114072395A (zh) 2019-04-26 2022-02-18 新基公司 杂环化合物及其治疗蠕虫感染和疾病的用途

Also Published As

Publication number Publication date
JP2023507173A (ja) 2023-02-21
MX2022007670A (es) 2022-07-19
CA3164098A1 (en) 2021-06-24
US20230148316A1 (en) 2023-05-11
EP4077281A1 (en) 2022-10-26
CN114845994A (zh) 2022-08-02
WO2021122911A1 (en) 2021-06-24
AU2020406093A1 (en) 2022-06-16

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