SE8800613D0
(sv)
|
1988-02-23 |
1988-02-23 |
Wallac Oy |
A novel spectrofluorometric method and compounds that are of value for the method
|
JPH03287584A
(ja)
|
1990-04-05 |
1991-12-18 |
Banyu Pharmaceut Co Ltd |
置換アリルアミン誘導体
|
US5250534A
(en)
|
1990-06-20 |
1993-10-05 |
Pfizer Inc. |
Pyrazolopyrimidinone antianginal agents
|
US6200980B1
(en)
|
1995-06-07 |
2001-03-13 |
Cell Pathways, Inc. |
Method of treating a patient having precancerous lesions with phenyl purinone derivatives
|
TR199902646T2
(xx)
|
1997-04-25 |
2000-05-22 |
Pfizer Inc. |
Seks�el bozuklu�un tedavisi i�in pirazolopirimidinonlar.
|
JP3721077B2
(ja)
|
1998-04-20 |
2005-11-30 |
ファイザー・インク |
性的不全を治療するためのピラゾロピリミジノンcGMPPDE5阻害剤
|
JP2000038350A
(ja)
|
1998-05-18 |
2000-02-08 |
Yoshitomi Pharmaceut Ind Ltd |
糖尿病治療薬
|
GB9823101D0
(en)
|
1998-10-23 |
1998-12-16 |
Pfizer Ltd |
Pharmaceutically active compounds
|
GB9823102D0
(en)
|
1998-10-23 |
1998-12-16 |
Pfizer Ltd |
Pharmaceutically active compounds
|
CZ27399A3
(cs)
|
1999-01-26 |
2000-08-16 |
Ústav Experimentální Botaniky Av Čr |
Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
|
IN187433B
(es)
|
1999-09-10 |
2002-04-27 |
Cipla Ltd |
|
AU1888800A
(en)
|
1999-09-13 |
2001-04-17 |
Cipla Limited |
A novel process for the synthesis of sildenafil citrate
|
EP1268481B1
(en)
|
1999-09-17 |
2007-12-12 |
Abbott GmbH & Co. KG |
Kinase inhibitors as therapeutic agents
|
HUP0203075A3
(en)
|
1999-09-24 |
2003-02-28 |
Nihon Nohyaku Co Ltd |
Aromatic diamide derivatives or salts thereof, agricultural/horticultural chemicals and method of using the same
|
TWI265925B
(en)
|
1999-10-11 |
2006-11-11 |
Pfizer |
Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them
|
CZ20021151A3
(cs)
|
1999-10-11 |
2003-03-12 |
Pfizer Inc. |
5-(2-substituovaný-5-heterocyklylsulfonylpyrid-3-yl)-dihydropyrazolo[4,3-d]-pyrimidin-7-ony jako inhibitory fosfodiesterasy
|
IL152925A
(en)
|
1999-10-21 |
2010-04-15 |
Pfizer |
Pharmaceutical preparations for the treatment of neurological disease containing an inhibitor of ring guanizine '3', 5 '- monophosphate phosphodiesterase 5 and one of gabapentin or pregabalin
|
KR100523718B1
(ko)
|
1999-12-22 |
2005-10-26 |
니혼노야쿠가부시키가이샤 |
방향족 디아미드 유도체, 농원예용 약제 및 이의 사용방법
|
CO5271697A1
(es)
|
2000-01-12 |
2003-04-30 |
Pfizer Prod Inc |
Composiciones y procedimientos para el tratamiento de afecciones que responden a un aumento de testosterona
|
US20020013327A1
(en)
|
2000-04-18 |
2002-01-31 |
Lee Andrew G. |
Compositions and methods for treating female sexual dysfunction
|
PT1294358E
(pt)
|
2000-06-28 |
2004-12-31 |
Smithkline Beecham Plc |
Processo de moagem por via humida
|
WO2002016348A1
(en)
|
2000-08-09 |
2002-02-28 |
Astrazeneca Ab |
Antiangiogenic bicyclic derivatives
|
AU2001284417A1
(en)
|
2000-09-05 |
2002-03-22 |
Taisho Pharmaceutical Co. Ltd. |
Hair growth stimulants
|
US6548508B2
(en)
|
2000-10-20 |
2003-04-15 |
Pfizer, Inc. |
Use of PDE V inhibitors for improved fecundity in mammals
|
AU2002222293A1
(en)
|
2000-12-19 |
2002-07-01 |
Smithkline Beecham P.L.C. |
Pyrazolo(3,4-c)pyridines as gsk-3 inhibitors
|
CA2431077A1
(en)
|
2000-12-19 |
2002-06-27 |
Merck Patent Gesellschaft Mit Beschraenkter Haftung |
Pharmaceutical formulation comprising pyrazolo[4,3-d]pyrimidines and antithrombotics, calcium antagonists, prostaglandins or prostaglandin derivatives
|
US6784185B2
(en)
|
2001-03-16 |
2004-08-31 |
Pfizer Inc. |
Pharmaceutically active compounds
|
US6770645B2
(en)
|
2001-03-16 |
2004-08-03 |
Pfizer Inc. |
Pharmaceutically active compounds
|
JP4196678B2
(ja)
|
2001-04-26 |
2008-12-17 |
味の素株式会社 |
複素環化合物
|
WO2002090347A1
(en)
|
2001-04-30 |
2002-11-14 |
Fujisawa Pharmaceutical Co., Ltd. |
Amide compounds
|
FR2825706B1
(fr)
|
2001-06-06 |
2003-12-12 |
Pf Medicament |
Nouveaux derives de benzothienyle ou d'indole, leur preparation et leur utilisation comme inhibiteurs de proteines prenyl transferase
|
PL370599A1
(en)
|
2001-11-02 |
2005-05-30 |
Pfizer Products Inc. |
Treatment of insulin resistance syndrome and type 2 diabetes with pde9 inhibitors
|
TW200303201A
(en)
|
2001-12-10 |
2003-09-01 |
Bristol Myers Squibb Co |
Synthesis of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones
|
US7166293B2
(en)
|
2002-03-29 |
2007-01-23 |
Carlsbad Technology, Inc. |
Angiogenesis inhibitors
|
US20050119278A1
(en)
|
2002-05-16 |
2005-06-02 |
Che-Ming Teng |
Anti-angiogenesis methods
|
TW200406385A
(en)
|
2002-05-31 |
2004-05-01 |
Eisai Co Ltd |
Pyrazole compound and pharmaceutical composition containing the same
|
ATE450533T1
(de)
|
2003-02-14 |
2009-12-15 |
Glaxo Group Ltd |
Carboxamidderivate
|
TW200418830A
(en)
|
2003-02-14 |
2004-10-01 |
Wyeth Corp |
Heterocyclyl-3-sulfonylazaindole or-azaindazole derivatives as 5-hydroxytryptamine-6 ligands
|
EP1613747A1
(en)
|
2003-03-31 |
2006-01-11 |
Pfizer Products Inc. |
Crystal structure of 3 ,5 -cyclic nucleotide phosphodiesterase 1b (pde1b) and uses thereof
|
RS20050810A
(en)
|
2003-04-29 |
2007-08-03 |
Pfizer Inc., |
5,7-diaminopyrazolo(4,3-d)pyrimidines useful in the treatment of hypertension
|
JP2006526660A
(ja)
|
2003-06-05 |
2006-11-24 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Vr1レセプターのモジュレーター
|
AU2004256841A1
(en)
|
2003-06-10 |
2005-01-20 |
Fulcrum Pharmaceuticals, Inc. |
Beta-lactamase inhibitors and methods of use thereof
|
EP1648448A4
(en)
|
2003-07-29 |
2009-04-01 |
Smithkline Beecham Corp |
CHEMICAL COMPOUNDS
|
AR045595A1
(es)
|
2003-09-04 |
2005-11-02 |
Vertex Pharma |
Composiciones utiles como inhibidores de proteinas quinasas
|
SI1682138T1
(sl)
|
2003-11-19 |
2011-04-29 |
Array Biopharma Inc |
HETEROCIKLIÄŚNI INHIBITORJI MEK-a
|
US20050137398A1
(en)
|
2003-12-22 |
2005-06-23 |
Jianguo Ji |
3-Quinuclidinyl heteroatom bridged biaryl derivatives
|
US7241773B2
(en)
|
2003-12-22 |
2007-07-10 |
Abbott Laboratories |
3-quinuclidinyl heteroatom bridged biaryl derivatives
|
GB0402137D0
(en)
|
2004-01-30 |
2004-03-03 |
Smithkline Beecham Corp |
Novel compounds
|
DE102004005172A1
(de)
|
2004-02-02 |
2005-08-18 |
Aventis Pharma Deutschland Gmbh |
Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
|
MXPA06009462A
(es)
|
2004-02-27 |
2007-03-15 |
Hoffmann La Roche |
Derivados pirazolo heteroaril fusionados.
|
BRPI0508036A
(pt)
|
2004-02-27 |
2007-07-17 |
Hoffmann La Roche |
derivados fundidos de pirazola
|
EP1720855A4
(en)
|
2004-03-02 |
2008-12-17 |
Smithkline Beecham Corp |
HEMMER OF ACT ACTIVITY
|
AR050188A1
(es)
|
2004-08-03 |
2006-10-04 |
Uriach Y Compania S A J |
Compuestos heterociclicos condensados utiles en terapia como inhibidores de quinasas p38 y composiciones farmaceuticas que los contienen
|
CN102964294A
(zh)
|
2004-09-02 |
2013-03-13 |
遗传技术研究公司 |
Hedgehog信号转导的吡啶基抑制剂
|
WO2006038001A1
(en)
|
2004-10-06 |
2006-04-13 |
Celltech R & D Limited |
Aminopyrimidine derivatives as jnk inhibitors
|
EP2332527A3
(en)
|
2004-10-20 |
2011-11-16 |
Resverlogix Corp. |
Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases
|
AR051596A1
(es)
|
2004-10-26 |
2007-01-24 |
Irm Llc |
Compuestos heterociclicos condensados nitrogenados como inhibidores de la actividad del receptor canabinoide 1; composiciones farmaceuticas que los contienen y su empleo en la preparacion de medicamentos para el tratamiento de trastornos alimentarios
|
WO2006050097A1
(en)
|
2004-10-28 |
2006-05-11 |
The Institutes For Pharmaceutical Discovery, Llc |
Substituted phenylalkanoic acids
|
WO2006053121A2
(en)
|
2004-11-10 |
2006-05-18 |
Cgi Pharmaceuticals, Inc. |
Imidazo[1 , 2-a] pyrazin-8-ylamines useful as modulators of kinase activity
|
US7919487B2
(en)
|
2004-11-10 |
2011-04-05 |
Synta Pharmaceuticals Corporation |
Heteroaryl compounds
|
US7696202B2
(en)
|
2004-11-10 |
2010-04-13 |
Synta Pharmaceuticals Corp. |
IL-12 modulatory compounds
|
DE102004054666A1
(de)
|
2004-11-12 |
2006-05-18 |
Bayer Cropscience Gmbh |
Substituierte Pyrazol-3-carboxamide, Verfahren zur Herstellung und Verwendung als Herbizide und Pflanzenwachstumsregulatoren
|
CN100516049C
(zh)
|
2004-11-16 |
2009-07-22 |
永信药品工业股份有限公司 |
抗血管生成药n2-(取代的芳基甲基)-3-(取代的苯基)吲唑的合成
|
MX2007008328A
(es)
|
2005-01-07 |
2008-01-16 |
Univ Emory |
Antagonistas cxcr4 para el tratamiento de trastornos medicos.
|
JP5023054B2
(ja)
|
2005-03-31 |
2012-09-12 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
抗バクテリア剤としての二環式ピラゾール化合物
|
US20070032493A1
(en)
|
2005-05-26 |
2007-02-08 |
Synta Pharmaceuticals Corp. |
Method for treating B cell regulated autoimmune disorders
|
US20100216798A1
(en)
|
2005-07-29 |
2010-08-26 |
Astellas Pharma Inc |
Fused heterocycles as lck inhibitors
|
WO2007019344A1
(en)
|
2005-08-04 |
2007-02-15 |
Sirtris Pharmaceuticals, Inc. |
Imidazo [2,1-b] thiayole derivatives as sirtuin modulating compounds
|
GB0516703D0
(en)
|
2005-08-15 |
2005-09-21 |
Syngenta Participations Ag |
Novel insecticides
|
JP2007055940A
(ja)
|
2005-08-24 |
2007-03-08 |
Astellas Pharma Inc |
ピラゾロピリミジン誘導体
|
MX2008002385A
(es)
|
2005-08-25 |
2008-03-18 |
Hoffmann La Roche |
Inhibidores de proteinas cinasas activads por mitogenos p38 y metodos para utilizarlos.
|
EP1919877A1
(en)
|
2005-08-25 |
2008-05-14 |
F.Hoffmann-La Roche Ag |
P38 map kinase inhibitors and methods for using the same
|
KR101011956B1
(ko)
|
2005-08-25 |
2011-01-31 |
에프. 호프만-라 로슈 아게 |
P38 mαp 키나아제 저해제 및 이의 사용 방법
|
CN101277939A
(zh)
|
2005-09-09 |
2008-10-01 |
布里斯托尔-迈尔斯斯奎布公司 |
无环ikur抑制剂
|
WO2007041511A2
(en)
|
2005-09-30 |
2007-04-12 |
New York University |
Hematopoietic progenitor kinase 1 for modulation of an immune response
|
EP1940296A2
(en)
|
2005-10-25 |
2008-07-09 |
SmithKline Beecham Corporation |
Chemical compounds
|
CA2627353A1
(en)
|
2005-11-03 |
2007-05-18 |
Ilypsa, Inc. |
Indole compounds having c4-acidic substituents and use thereof as phospholipase-a2 inhibitors
|
RU2008126228A
(ru)
|
2005-11-30 |
2010-01-10 |
Астеллас Фарма Инк. (Jp) |
2-аминобензамидное производное
|
GB0525143D0
(en)
|
2005-12-09 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
EP1979325A1
(en)
|
2006-01-11 |
2008-10-15 |
AstraZeneca AB |
Morpholino pyrimidine derivatives and their use in therapy
|
AU2007214661B2
(en)
|
2006-02-16 |
2012-05-17 |
Syngenta Limited |
Pesticides containing a bicyclic bisamide structure
|
EP2004626A4
(en)
|
2006-03-23 |
2010-10-27 |
Synta Pharmaceuticals Corp |
BENZIMIDAZOLYL-PYRIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION AND IMMUNE DISORDERS
|
PL1999132T3
(pl)
|
2006-03-30 |
2012-12-31 |
Irm Llc |
Azolopirymidyny jako inhibitory aktywności Receptora Kannabinoidowego typu 1
|
EP2018380B1
(en)
|
2006-05-19 |
2011-10-19 |
Abbott Laboratories |
Cns active fused bicycloheterocycle substituted azabicyclic alkane derivatives
|
US20080280891A1
(en)
|
2006-06-27 |
2008-11-13 |
Locus Pharmaceuticals, Inc. |
Anti-cancer agents and uses thereof
|
WO2008008059A1
(en)
|
2006-07-12 |
2008-01-17 |
Locus Pharmaceuticals, Inc. |
Anti-cancer agents ans uses thereof
|
PE20080403A1
(es)
|
2006-07-14 |
2008-04-25 |
Amgen Inc |
Derivados heterociclicos fusionados y metodos de uso
|
GB0614691D0
(en)
|
2006-07-24 |
2006-08-30 |
Syngenta Participations Ag |
Insecticidal compounds
|
AU2007308045A1
(en)
|
2006-10-06 |
2008-04-17 |
Irm Llc |
Protein kinase inhibitors and methods for using thereof
|
MX2009003941A
(es)
|
2006-10-20 |
2009-04-24 |
Concert Pharmaceuticals Inc |
Derivados de 3-(dihidro-1h-pirazolo[4,3-d]pirimidin-5-il)-4-propox ibencenosulfonamida y metodos de uso.
|
US20080200458A1
(en)
|
2007-01-18 |
2008-08-21 |
Joseph Barbosa |
Methods and compositions for the treatment of body composition disorders
|
US20080194557A1
(en)
|
2007-01-18 |
2008-08-14 |
Joseph Barbosa |
Methods and compositions for the treatment of pain, inflammation and cancer
|
US20140249135A1
(en)
*
|
2007-03-01 |
2014-09-04 |
Novartis Ag |
Pim kinase inhibitors and methods of their use
|
MX2009009304A
(es)
*
|
2007-03-01 |
2009-11-18 |
Novartis Ag |
Inhibidores de cinasa pim y metodos para su uso.
|
EP2002835A1
(en)
|
2007-06-04 |
2008-12-17 |
GenKyo Tex |
Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
|
CL2008001822A1
(es)
*
|
2007-06-20 |
2009-03-13 |
Sirtris Pharmaceuticals Inc |
Compuestos derivados de tiazolo[5,4-b]piridina; composicion farmaceutica que comprende a dichos compuestos; y uso del compuesto en el tratamiento de la resistencia a la insulina, sindrome metabolico, diabetes, entre otras.
|
JP5241834B2
(ja)
*
|
2007-07-19 |
2013-07-17 |
メルク・シャープ・アンド・ドーム・コーポレーション |
プロテインキナーゼ阻害剤としての複素環アミド化合物
|
MY146643A
(en)
|
2007-07-30 |
2012-09-14 |
Dae Woong Pharma |
Novel benzoimidazole derivatives and pharmaceutical composition comprising the same
|
MX2010001446A
(es)
|
2007-08-08 |
2010-03-01 |
Merck Serono Sa |
Derivados de 6-amino-pirimidina-4-carboxamida y compuestos relacionados que se enlazan a los receptores para esfingosina 1-fosfato (s1p) para el tratamiento de esclerosis multiple.
|
GB0716414D0
(en)
|
2007-08-22 |
2007-10-03 |
Syngenta Participations Ag |
Novel insecticides
|
WO2009032651A1
(en)
|
2007-08-31 |
2009-03-12 |
Smithkline Beecham Corporation |
Inhibitors of akt activity
|
WO2009038784A1
(en)
|
2007-09-21 |
2009-03-26 |
Amgen Inc. |
Triazole fused heteroaryl compounds as p38 kinase inhibitors
|
KR20100092000A
(ko)
|
2007-11-01 |
2010-08-19 |
서트리스 파마슈티컬즈, 인코포레이티드 |
시르투인 조절제로서의 아미드 유도체
|
KR100963644B1
(ko)
|
2007-11-23 |
2010-06-15 |
한국과학기술연구원 |
피라졸로피리미딘온 유도체 및 그의 제조방법
|
JP5525456B2
(ja)
|
2008-02-04 |
2014-06-18 |
マーキュリー セラピューティクス,インコーポレイテッド |
Ampk調節因子
|
EP2273882A4
(en)
|
2008-05-13 |
2011-07-13 |
Poniard Pharmaceuticals Inc |
BIOACTIVE COMPOUNDS FOR THE TREATMENT OF CANCER AND NEURODEEGENERATIVE DISEASES
|
CN102089278A
(zh)
|
2008-06-11 |
2011-06-08 |
Irm责任有限公司 |
用于治疗疟疾的化合物和组合物
|
ES2711249T3
(es)
|
2008-06-27 |
2019-04-30 |
Celgene Car Llc |
Compuestos de heteroarilo y usos de los mismos
|
US20110294853A1
(en)
|
2008-09-12 |
2011-12-01 |
Benjamin Pelcman |
Bis Aromatic Compounds for Use in the Treatment of Inflammation
|
EP2166010A1
(en)
|
2008-09-23 |
2010-03-24 |
Genkyo Tex Sa |
Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
|
EP2165707A1
(en)
|
2008-09-23 |
2010-03-24 |
Genkyo Tex Sa |
Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
|
EP2166008A1
(en)
|
2008-09-23 |
2010-03-24 |
Genkyo Tex Sa |
Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
|
WO2010046780A2
(en)
|
2008-10-22 |
2010-04-29 |
Institut Pasteur Korea |
Anti viral compounds
|
JP2010111624A
(ja)
|
2008-11-06 |
2010-05-20 |
Shionogi & Co Ltd |
Ttk阻害作用を有するインダゾール誘導体
|
JP5770102B2
(ja)
|
2008-12-19 |
2015-08-26 |
ジェネンテック, インコーポレイテッド |
複素環化合物と使用方法
|
KR20100101056A
(ko)
|
2009-03-07 |
2010-09-16 |
주식회사 메디젠텍 |
세포핵에서 세포질로의 gsk3의 이동을 억제하는 화합물을 함유하는 세포핵에서 세포질로의 gsk3 이동에 의해 발생되는 질환의 치료 또는 예방용 약학적 조성물
|
AR076126A1
(es)
|
2009-03-18 |
2011-05-18 |
Schering Corp |
Compuestos biciclicos como inhibidores de diacilglicerol aciltransferasa
|
EP2411328B1
(en)
|
2009-03-26 |
2019-07-24 |
Northeastern University |
Carbon nanostructures from pyrolysis of organic materials
|
WO2010118367A2
(en)
|
2009-04-10 |
2010-10-14 |
Progenics Pharmaceuticals, Inc. |
Antiviral pyrimidines
|
US8846673B2
(en)
|
2009-08-11 |
2014-09-30 |
Bristol-Myers Squibb Company |
Azaindazoles as kinase inhibitors and use thereof
|
EP2477498A4
(en)
|
2009-09-14 |
2013-02-27 |
Merck Sharp & Dohme |
DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS
|
WO2011050245A1
(en)
|
2009-10-23 |
2011-04-28 |
Yangbo Feng |
Bicyclic heteroaryls as kinase inhibitors
|
ES2360333B1
(es)
|
2009-10-29 |
2012-05-04 |
Consejo Superior De Investigaciones Cientificas (Csic) (70%) |
Derivados de bis (aralquil) amino y sistemas (hetero) aromaticos de seis miembros y su uso en el tratamiento de patologias neurodegenerativas, incluida la enfermedad de alzheimer
|
JP2013032290A
(ja)
|
2009-11-20 |
2013-02-14 |
Dainippon Sumitomo Pharma Co Ltd |
新規縮合ピリミジン誘導体
|
WO2011078143A1
(ja)
|
2009-12-22 |
2011-06-30 |
塩野義製薬株式会社 |
ピリミジン誘導体およびそれらを含有する医薬組成物
|
EP2519517B1
(en)
|
2009-12-29 |
2015-03-25 |
Dana-Farber Cancer Institute, Inc. |
Type ii raf kinase inhibitors
|
US20130022629A1
(en)
|
2010-01-04 |
2013-01-24 |
Sharpe Arlene H |
Modulators of Immunoinhibitory Receptor PD-1, and Methods of Use Thereof
|
US20130109758A1
(en)
|
2010-01-06 |
2013-05-02 |
The University Of British Columbia |
Bisphenol derivative therapeutics and methods for their use
|
DE102010009903A1
(de)
|
2010-03-02 |
2011-09-08 |
Merck Patent Gmbh |
Verbindungen für elektronische Vorrichtungen
|
CN102206172B
(zh)
|
2010-03-30 |
2015-02-25 |
中国医学科学院医药生物技术研究所 |
一组取代双芳基化合物及其制备方法和抗病毒应用
|
EP2560488B1
(en)
|
2010-04-23 |
2015-10-28 |
Cytokinetics, Inc. |
Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
|
JP6112486B2
(ja)
|
2010-04-27 |
2017-04-12 |
カルシメディカ,インク. |
細胞内カルシウムを調節する化合物
|
GB201008134D0
(en)
|
2010-05-14 |
2010-06-30 |
Medical Res Council Technology |
Compounds
|
JP2011246389A
(ja)
|
2010-05-26 |
2011-12-08 |
Oncotherapy Science Ltd |
Ttk阻害作用を有する縮環ピラゾール誘導体
|
EP2576539B1
(de)
|
2010-05-27 |
2017-12-13 |
Bayer CropScience AG |
Pyridinylcarbonsäure derivate als fungizide
|
WO2011153553A2
(en)
|
2010-06-04 |
2011-12-08 |
The Regents Of The University Of California |
Methods and compositions for kinase inhibition
|
KR20130087495A
(ko)
|
2010-06-15 |
2013-08-06 |
바이엘 인텔렉쳐 프로퍼티 게엠베하 |
안트라닐산 유도체
|
WO2011158108A2
(en)
|
2010-06-16 |
2011-12-22 |
Purdue Pharma L.P. |
Aryl substituted indoles and the use thereof
|
JP5926727B2
(ja)
|
2010-07-28 |
2016-05-25 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH |
置換イミダゾ[1,2−b]ピリダジン
|
JP5844376B2
(ja)
|
2010-10-06 |
2016-01-13 |
ジェイファーマ株式会社 |
強力な尿酸トランスポーター阻害剤の開発:それらの尿酸排泄効果のために設計された化合物
|
GB201017345D0
(en)
|
2010-10-14 |
2010-11-24 |
Proximagen Ltd |
Receptor antagonists
|
EP2796456A1
(en)
|
2010-12-09 |
2014-10-29 |
Amgen Inc. |
Bicyclic compounds as Pim inhibitors
|
UY33808A
(es)
|
2010-12-17 |
2012-07-31 |
Syngenta Participations Ag |
Compuestos insecticidas
|
CN103402996B
(zh)
|
2011-01-04 |
2015-02-11 |
诺瓦提斯公司 |
可用于治疗年龄相关性黄斑变性(amd)的吲哚化合物或其类似物
|
EP2672820B1
(en)
|
2011-02-07 |
2019-04-17 |
The Washington University |
Mannoside compounds and methods of use thereof
|
CA2828824A1
(en)
|
2011-03-28 |
2012-10-04 |
F. Hoffmann-La Roche Ag |
Thiazolopyrimidine compounds
|
MX342104B
(es)
|
2011-04-12 |
2016-09-13 |
Chong Kun Dang Pharmaceutical Corp |
Derivados de cicloalquenil arilo para inhibidor de cetp.
|
US9802937B2
(en)
|
2011-04-21 |
2017-10-31 |
Origenis Gmbh |
Substituted pyrazolo{4,3-D}pyrimidines as kinase inhibitors
|
US9328075B2
(en)
*
|
2011-05-05 |
2016-05-03 |
St. Jude Children's Research Hospital |
Pyrimidinone compounds and methods for treating influenza
|
US20140288069A1
(en)
|
2011-05-17 |
2014-09-25 |
Bayer Intellectual Property Gmbh |
Amino-substituted imidazopyridazines as mknk1 kinase inhibitors
|
WO2012158810A1
(en)
|
2011-05-17 |
2012-11-22 |
Principia Biopharma Inc. |
Tyrosine kinase inhibitors
|
UY34104A
(es)
|
2011-05-31 |
2013-01-03 |
Syngenta Participations Ag |
?compuestos derivados benzamídicos heterocíclicos, procesos e intermedios para su preparación, composiciones y métodos para su uso?.
|
ES2625854T3
(es)
|
2011-06-01 |
2017-07-20 |
Bayer Intellectual Property Gmbh |
Aminoimidazopiridazinas sustituidas
|
ES2610366T3
(es)
|
2011-06-22 |
2017-04-27 |
Bayer Intellectual Property Gmbh |
Heterociclil-aminoimidazopiridazinas
|
EP2543372A1
(en)
|
2011-07-08 |
2013-01-09 |
Helmholtz-Zentrum für Infektionsforschung GmbH |
Medicament for the treatment of liver cancer
|
ES2627120T3
(es)
|
2011-07-08 |
2017-07-26 |
Helmholtz-Zentrum für Infektionsforschung GmbH |
Medicamento para el tratamiento del cáncer de hígado
|
US9394293B2
(en)
|
2011-08-10 |
2016-07-19 |
Purdue Pharma L.P. |
TRPV1 antagonists including dihydroxy substituent and uses thereof
|
JP6133291B2
(ja)
|
2011-08-12 |
2017-05-24 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
ピラゾロ[3,4−c]ピリジン化合物と使用方法
|
CN103889976A
(zh)
|
2011-08-12 |
2014-06-25 |
弗·哈夫曼-拉罗切有限公司 |
吲唑化合物、组合物及使用方法
|
WO2013042137A1
(en)
|
2011-09-19 |
2013-03-28 |
Aurigene Discovery Technologies Limited |
Bicyclic heterocycles as irak4 inhibitors
|
CN103814029B
(zh)
|
2011-09-23 |
2016-10-12 |
拜耳知识产权有限责任公司 |
取代的咪唑并哒嗪
|
CN102516263B
(zh)
|
2011-10-25 |
2015-04-08 |
南方医科大学 |
一种螺三环类化合物及其制备方法、以及含该类化合物的药物组合物及其应用
|
CN102503959B
(zh)
|
2011-10-25 |
2015-04-08 |
南方医科大学 |
一种稠三环类化合物及其制备方法、以及含该类化合物的药物组合物及其应用
|
MX343561B
(es)
|
2011-11-01 |
2016-11-09 |
Hoffmann La Roche |
Compuestos de imidazolpiridazina.
|
JP6200903B2
(ja)
|
2012-02-17 |
2017-09-20 |
キネタ フォー エルエルシー |
アレナウイルス感染症の治療のための抗ウイルス薬
|
TW201348231A
(zh)
|
2012-02-29 |
2013-12-01 |
Amgen Inc |
雜雙環化合物
|
EP2824099A4
(en)
|
2012-03-09 |
2015-11-11 |
Carna Biosciences Inc |
NOVEL TRIAZINE DERIVATIVE
|
JP6101248B2
(ja)
|
2012-03-28 |
2017-03-22 |
出光興産株式会社 |
新規化合物、有機エレクトロルミネッセンス素子用材料および有機エレクトロルミネッセンス素子
|
PE20141558A1
(es)
|
2012-04-20 |
2014-11-06 |
Gilead Sciences Inc |
Derivados de acido benzotiazol-6-il acetico y su uso para tratar una infeccion por vih
|
WO2014003405A1
(ko)
|
2012-06-26 |
2014-01-03 |
주식회사 제이앤드제이 캐미칼 |
신규한 화합물 및 이를 포함하는 발광소자
|
JP2015522007A
(ja)
|
2012-06-28 |
2015-08-03 |
ノバルティス アーゲー |
ピロリジン誘導体、および補体経路モジュレーターとしてのその使用
|
KR101936851B1
(ko)
|
2012-07-16 |
2019-01-11 |
한국과학기술연구원 |
단백질 키나아제 저해제인 신규 피라졸로피리딘 유도체 또는 인다졸 유도체
|
WO2014024125A1
(en)
|
2012-08-08 |
2014-02-13 |
Celon Pharma S.A. |
Pyrazolo[4,3-d]pyrimidin-7(6h)-one derivatives as pde9 inhibitors
|
US20150239889A1
(en)
|
2012-08-23 |
2015-08-27 |
Mitsubishi Tanabe Pharma Corporation |
Pyrazolopyrimidine compound
|
US9882150B2
(en)
|
2012-09-24 |
2018-01-30 |
Arizona Board Of Regents For And On Behalf Of Arizona State University |
Metal compounds, methods, and uses thereof
|
EA201590693A1
(ru)
|
2012-10-05 |
2015-08-31 |
Ригель Фармасьютикалс, Инк. |
Ингибиторы gdf-8
|
KR102137472B1
(ko)
|
2013-02-08 |
2020-07-27 |
삼성디스플레이 주식회사 |
유기 발광 소자
|
US9242969B2
(en)
|
2013-03-14 |
2016-01-26 |
Novartis Ag |
Biaryl amide compounds as kinase inhibitors
|
EP2968304B1
(en)
|
2013-03-14 |
2018-10-10 |
The Trustees of Columbia University in the City of New York |
4-phenylpiperidines, their preparation and use
|
UY35464A
(es)
|
2013-03-15 |
2014-10-31 |
Araxes Pharma Llc |
Inhibidores covalentes de kras g12c.
|
US9034927B2
(en)
|
2013-05-22 |
2015-05-19 |
Curza Global, Llc |
Methods of use for compositions comprising a biocidal polyamine
|
CN110003279A
(zh)
|
2013-06-10 |
2019-07-12 |
代表亚利桑那大学的亚利桑那校董会 |
具有改进的发射光谱的磷光四齿金属络合物
|
US9718818B2
(en)
|
2013-08-22 |
2017-08-01 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
TWI652014B
(zh)
|
2013-09-13 |
2019-03-01 |
美商艾佛艾姆希公司 |
雜環取代之雙環唑殺蟲劑
|
WO2015037965A1
(en)
|
2013-09-16 |
2015-03-19 |
Rohm And Haas Electronic Materials Korea Ltd. |
Novel organic electroluminescent compounds and organic electroluminescent device comprising the same
|
EP3057954A2
(en)
|
2013-10-18 |
2016-08-24 |
Syros Pharmaceuticals, Inc. |
Heteromaromatic compounds useful for the treatment of proliferative diseases
|
SG11201602387RA
(en)
|
2013-10-21 |
2016-05-30 |
Merck Patent Gmbh |
Heteroaryl compounds as btk inhibitors and uses thereof
|
EP3080122B1
(en)
|
2013-12-11 |
2018-10-31 |
Biogen MA Inc. |
Biaryl compounds useful for the treatment of human diseases in oncology, neurology and immunology
|
JP6879740B2
(ja)
|
2013-12-13 |
2021-06-02 |
ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド |
リンパ形質細胞性リンパ腫を処置する方法
|
TWI667233B
(zh)
|
2013-12-19 |
2019-08-01 |
德商拜耳製藥公司 |
新穎吲唑羧醯胺,其製備方法、含彼等之醫藥製劑及其製造醫藥之用途
|
WO2015090235A1
(en)
|
2013-12-20 |
2015-06-25 |
Sunshine Lake Pharma Co., Ltd. |
Substituted piperazine compounds and methods of use thereof
|
US10160753B2
(en)
|
2014-01-10 |
2018-12-25 |
Aurigene Discovery Technologies Limited |
Indazole compounds as IRAK4 inhibitors
|
EP3102650B1
(de)
|
2014-02-05 |
2018-08-29 |
Merck Patent GmbH |
Metallkomplexe
|
KR20160116018A
(ko)
|
2014-02-25 |
2016-10-06 |
아칠리온 파르마세우티칼스 인코포레이티드 |
보체 매개 질환의 치료를 위한 아미드 화합물
|
US9871208B2
(en)
|
2014-02-26 |
2018-01-16 |
Samsung Display Co., Ltd. |
Condensed cyclic compound and organic light-emitting device including the same
|
WO2015164956A1
(en)
|
2014-04-29 |
2015-11-05 |
The University Of British Columbia |
Benzisothiazole derivative compounds as therapeutics and methods for their use
|
US20150328188A1
(en)
|
2014-05-19 |
2015-11-19 |
Everardus O. Orlemans |
Combination Therapies for the Treatment of Proliferative Disorders
|
CN106488917B
(zh)
|
2014-06-18 |
2020-05-05 |
默克专利有限公司 |
用于有机电致发光器件的材料
|
WO2015193846A1
(en)
|
2014-06-20 |
2015-12-23 |
Aurigene Discovery Technologies Limited |
Substituted indazole compounds as irak4 inhibitors
|
EP3157904B1
(en)
|
2014-06-20 |
2020-11-18 |
Institut Pasteur Korea |
Anti-infective compounds
|
US20170247366A1
(en)
|
2014-06-25 |
2017-08-31 |
Vanderbilt University |
Substituted 4-alkoxypicolinamide analogs as mglur5 negative allosteric modulators and methods of making and using the same
|
KR20160007967A
(ko)
|
2014-07-10 |
2016-01-21 |
삼성디스플레이 주식회사 |
유기 발광 소자
|
WO2016040181A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
WO2016040188A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
WO2016040180A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
WO2016040184A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
WO2016041618A1
(en)
|
2014-09-15 |
2016-03-24 |
Merck Patent Gmbh |
Substituted indazoles and related heterocycles
|
ES2907622T3
(es)
|
2014-10-06 |
2022-04-25 |
Merck Patent Gmbh |
Compuestos de heteroarilo como inhibidores de BTK y usos de estos
|
JO3705B1
(ar)
|
2014-11-26 |
2021-01-31 |
Bayer Pharma AG |
إندازولات مستبدلة جديدة، عمليات لتحضيرها، مستحضرات دوائية تحتوي عليها واستخدامها في إنتاج أدوية
|
WO2016090300A1
(en)
|
2014-12-05 |
2016-06-09 |
Genentech, Inc. |
Methods and compositions for treating cancer using pd-1 axis antagonists and hpk1 antagonists
|
JP6772188B2
(ja)
|
2015-02-03 |
2020-10-21 |
メルク、パテント、ゲゼルシャフト、ミット、ベシュレンクテル、ハフツングMerck Patent GmbH |
金属錯体
|
WO2016144702A1
(en)
|
2015-03-06 |
2016-09-15 |
Pharmakea, Inc. |
Lysyl oxidase-like 2 inhibitors and uses thereof
|
CN107635984B
(zh)
|
2015-03-11 |
2021-04-13 |
Fmc公司 |
杂环取代的二环唑杀有害生物剂
|
WO2016161571A1
(en)
|
2015-04-08 |
2016-10-13 |
Merck Sharp & Dohme Corp. |
Indazole and azaindazole btk inhibitors
|
US20180289685A1
(en)
|
2015-04-30 |
2018-10-11 |
Bayer Pharma Aktiengesellschaft |
Combinations of inhibitors of irak4 with inhibitors of btk
|
KR20240000617A
(ko)
*
|
2015-06-25 |
2024-01-02 |
유니버시티 헬스 네트워크 |
Hpk1 억제제 및 이의 사용 방법
|
EA201890308A1
(ru)
|
2015-07-15 |
2018-08-31 |
Ориджин Дискавери Текнолоджиз Лимитед |
Замещенные азасоединения как ингибиторы irak-4
|
KR20180025896A
(ko)
|
2015-07-15 |
2018-03-09 |
오리진 디스커버리 테크놀로지스 리미티드 |
Irak-4 저해제로서 인다졸 및 아자인다졸 화합물
|
WO2017023972A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
|
EP3331530A4
(en)
|
2015-08-03 |
2018-12-19 |
Raze Therapeutics Inc. |
Mthfd2 inhibitors and uses thereof
|
EP3331525B1
(en)
|
2015-08-07 |
2020-10-07 |
Calcimedica, Inc. |
Use of crac channel inhibitors for the treatment of stroke and traumatic brain injury
|
WO2017045955A1
(en)
|
2015-09-14 |
2017-03-23 |
Basf Se |
Heterobicyclic compounds
|
WO2017058915A1
(en)
|
2015-09-28 |
2017-04-06 |
Araxes Pharma Llc |
Inhibitors of kras g12c mutant proteins
|
WO2017108744A1
(de)
|
2015-12-22 |
2017-06-29 |
Bayer Pharma Aktiengesellschaft |
Neue substituierte indazole, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln
|
EP3399968B8
(en)
|
2016-01-07 |
2021-12-01 |
Xuanzhu Biopharmaceutical Co., Ltd. |
Selective inhibitors of clinically important mutants of the egfr tyrosine kinase
|
EP3487450A1
(en)
|
2016-07-19 |
2019-05-29 |
Bolle, Francis |
Artificial accommodating lens complex
|
CN110818690B
(zh)
|
2016-07-26 |
2021-08-10 |
深圳市塔吉瑞生物医药有限公司 |
用于抑制蛋白酪氨酸激酶活性的氨基嘧啶类化合物
|
US20180072718A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridine compounds and uses thereof
|
WO2018049191A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridone derivatives as hpk1 modulators and uses thereof for the treatment of cancer
|
AR109595A1
(es)
|
2016-09-09 |
2018-12-26 |
Incyte Corp |
Compuestos de pirazolopirimidina y usos de estos como inhibidores de hpk1
|
AR109596A1
(es)
|
2016-09-09 |
2018-12-26 |
Incyte Corp |
Compuestos pirazolopiridina y sus usos
|
US20180228786A1
(en)
|
2017-02-15 |
2018-08-16 |
Incyte Corporation |
Pyrazolopyridine compounds and uses thereof
|
WO2019051199A1
(en)
|
2017-09-08 |
2019-03-14 |
Incyte Corporation |
6-CYANO-INDAZOLE COMPOUNDS AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) MODULATORS
|
WO2019164847A1
(en)
|
2018-02-20 |
2019-08-29 |
Incyte Corporation |
Indazole compounds and uses thereof
|
SI3755703T1
(sl)
|
2018-02-20 |
2022-11-30 |
Incyte Corporation |
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|
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