CN110291087B - 作为雌激素受体降解剂的四氢萘和四氢异喹啉衍生物 - Google Patents
作为雌激素受体降解剂的四氢萘和四氢异喹啉衍生物 Download PDFInfo
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- CN110291087B CN110291087B CN201780085150.9A CN201780085150A CN110291087B CN 110291087 B CN110291087 B CN 110291087B CN 201780085150 A CN201780085150 A CN 201780085150A CN 110291087 B CN110291087 B CN 110291087B
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
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- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010214256.8A CN111454248A (zh) | 2016-12-01 | 2017-12-01 | 作为雌激素受体降解剂的四氢萘和四氢异喹啉衍生物 |
| CN202410799699.6A CN118834201A (zh) | 2016-12-01 | 2017-12-01 | 作为雌激素受体降解剂的四氢萘和四氢异喹啉衍生物 |
| CN202210386845.3A CN114656452B (zh) | 2016-12-01 | 2017-12-01 | 作为雌激素受体降解剂的四氢萘和四氢异喹啉衍生物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662429041P | 2016-12-01 | 2016-12-01 | |
| US62/429,041 | 2016-12-01 | ||
| US201762540049P | 2017-08-01 | 2017-08-01 | |
| US62/540,049 | 2017-08-01 | ||
| PCT/US2017/064283 WO2018102725A1 (en) | 2016-12-01 | 2017-12-01 | Tetrahydronaphthalene and tetrahydroisoquinoline derivatives as estrogen receptor degraders |
Related Child Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210386845.3A Division CN114656452B (zh) | 2016-12-01 | 2017-12-01 | 作为雌激素受体降解剂的四氢萘和四氢异喹啉衍生物 |
| CN202010214256.8A Division CN111454248A (zh) | 2016-12-01 | 2017-12-01 | 作为雌激素受体降解剂的四氢萘和四氢异喹啉衍生物 |
| CN202410799699.6A Division CN118834201A (zh) | 2016-12-01 | 2017-12-01 | 作为雌激素受体降解剂的四氢萘和四氢异喹啉衍生物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110291087A CN110291087A (zh) | 2019-09-27 |
| CN110291087B true CN110291087B (zh) | 2024-07-09 |
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