CN109789296B - 具有向远侧延伸的线圈和可成形末端的导丝装置 - Google Patents

具有向远侧延伸的线圈和可成形末端的导丝装置 Download PDF

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CN109789296B
CN109789296B CN201780057216.3A CN201780057216A CN109789296B CN 109789296 B CN109789296 B CN 109789296B CN 201780057216 A CN201780057216 A CN 201780057216A CN 109789296 B CN109789296 B CN 109789296B
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约翰·A·李波特
爱德华杰·斯奈德
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Abstract

本公开涉及具有可成形末端和有效扭转能力的导丝装置。导丝装置包括具有近侧区段和逐渐变细的远侧区段的芯。管结构联接到芯,使得芯的逐渐变细的远侧区段延伸到管结构中并且向远侧延伸超过管结构。芯的向远侧延伸超过管的部分形成可成形末端。一个或多个线圈还向远侧延伸超过管。末端构造成减小来自管结构的弹性力破坏末端的定制形状的趋势。

Description

具有向远侧延伸的线圈和可成形末端的导丝装置
相关申请的交叉引用
本申请要求2017年6月1日提交的题为“GUIDEWIRE DEVICES HAVING DISALLYEXTENDING COILS AND SHAPEABLE TIPS(具有向远侧延伸线圈和可成形末端的导丝装置)”的美国专利申请序列号15/611,328以及2016年7月18日提交的题为“GUIDEWIRE DEVICESHAVING SHAPEABLE TIPS(具有可成形末端的导丝装置)”的美国临时专利申请序列号62/363,760的优先权和权益。所有上述申请均通过引用整体并入本文。
背景技术
导丝装置通常用于将导管或其他介入装置导引或引导至患者体内的目标解剖位置。通常,导丝进入并穿过患者的脉管系统以便到达目标位置,该目标位置例如可以在患者的心脏或神经血管组织处或附近。通常使用放射摄影成像来帮助将导丝导航到目标位置。在许多情况下,在介入手术期间导丝留在身体内的适当位置,其中导丝可用于将多个导管或其他介入装置引导到目标解剖位置。
一些导丝装置被构造成具有弯曲或弯折的末端,以使操作者能够更好地导航(navigate,走行)于患者的脉管系统。利用这种导丝,操作者能将扭矩应用到导丝的近端或所附接的近侧手柄,目的是将末端朝向并指向期望的方向。然后,操作者可以在患者的脉管系统中在期望的方向上进一步导向导丝。
调整导丝装置(特别是导丝装置的远侧区段)的柔性也是一个问题。在许多情况下,相对高水平的柔性是期望的,目的是提供给导丝足够的可弯折性,以使导丝能够成角度地通过脉管系统通道的曲折的弯折和弯曲而到达目标区域。例如,将导丝导向到神经血管系统的部分需要导丝通过弯曲的通道,诸如颈动脉虹吸部和其他曲折路径。
与导丝装置有关的另一个问题是给定导丝装置从近端向远端传递扭矩的能力(即,导丝装置的“扭转能力”)。随着导丝的更多部分进入并穿过脉管系统通道,导丝与脉管系统之间的摩擦表面接触量增加,阻碍导丝容易地移动通过脉管系统通道。具有良好扭转能力的导丝使得近端处的扭矩力能够通过导丝被传递到远端,从而使得导丝能够旋转并克服摩擦力。
一些导丝装置包括位于导丝芯的远端上方的远侧放置的微机械加工的海波管(hypotube),目的是朝向装置的端部进一步向远侧导向所应用的扭转力。因为主要通过构件的横截面的外部区段传递扭转力,所以管被构造成提供一路径,从而用于传递与未被管套住的导丝芯所传递的扭矩量相比增加的扭矩。
虽然所述导丝装置提供了许多益处,但仍存在若干局限性。例如,具有扭矩传递管的导丝的许多设计特征,虽然起到提供增加的扭矩传递的作用,但是其不利于且限制了导丝末端的可成形性。
发明内容
本公开涉及具有可成形末端和有效扭转能力的导丝装置。在一实施例中,导丝装置包括具有近侧区段和远侧区段的芯。远侧区段可以逐渐变细到比近侧区段更小的直径。管结构联接到芯,使得芯的远侧区段进入管结构并向远侧超过管结构之外以形成可成形末端。导丝装置还包括内部线圈,其包裹芯的远侧部分的至少一部分。内部线圈定位成使得内部线圈的近侧部分设置在芯的外表面与管结构的内表面之间,并且使得内部线圈的远侧部分向外侧延伸超过管结构,以包裹可成形末端的至少一部分。导丝装置还包括联接到管结构远端的外部线圈,该外部线圈从管结构向外侧延伸。外部线圈定位成包裹内部线圈的至少一部分。末端构造成减小来自管结构的弹性力破坏末端的定制形状的趋势。
在一个实施例中,芯由不锈钢形成和/或包括不锈钢,管结构由超弹性材料(诸如镍钛诺(nitinol,镍钛合金))形成和/或包括所述超弹性材料,内部线圈由不透射线的材料(诸如铂)形成和/或包括所述不透射线的材料,以及外部线圈由不锈钢形成和/或包括所述不锈钢。
在一些实施例中,管结构包括多个窗孔,所述窗孔限定与多个周向延伸的环联接的多个轴向延伸的梁。管结构可包括单梁切口图案、双梁切口图案、三梁切口图案或多于三个梁的切口图案中的一种或多种。在一些实施例中,在连续的段之间施加旋转的偏移,以使沿管结构长度的优选弯曲方向最小化。
另外的特征和优点将部分地在下面的描述中阐述,并且从描述中部分地显而易见,或者可以通过本文公开的实施例的实践来学习。借助于所附权利要求中特别指出的元件和组合,将明白和获得本文公开的实施例的目的和优点。应理解,前述简要概述和以下详细描述都仅是示例性和解释性的,而不限制本文公开的或如所要求保护的实施方案。
附图说明
为了描述可以获得本发明的上述和其他优点和特征的方式,将通过参考附图中所示的具体实施例来给出上面简要描述的本发明的更具体的描述。应理解,这些附图仅描绘了本发明的典型实施例,因此不应认为是对其范围的限制,本发明将通过使用附图用附加的特征和细节来描述和解释,在附图中:
图1示出了导丝装置的示例性实施例,该导丝装置提供有效的扭转能力并具有可成形末端;
图2是图1的导丝装置的横截面图;
图3至图8示出了可以在导丝装置的管中形成的各种示例性切口图案;以及
图9至图11示出了可与导丝装置一起使用的各种远侧末端构造。
具体实施方式
介绍
本公开涉及提供有效解剖学导航性能的导丝装置。将导丝引导和导向至目标解剖位置的能力取决于平衡和最优化扭转能力与维持成形末端的能力之间的权衡。导丝装置可包括可成形末端,以允许操作者通过旋转远侧末端而将该末端指向脉管系统内的期望方向。然而,如果这种导丝装置的扭转能力不足,则操作者将不能将扭转力一直传递到成形的远侧末端以控制成形的远侧末端的定向。随着导丝装置进一步进入脉管系统并且受到增大的摩擦阻力,这种障碍将变得越来越成问题。另外,如果导丝装置不能正确地形成并维持成形末端,则其调整末端定向的能力有限,使得血管内导航更加困难。
本文描述的实施例提供平衡和/或最优化导丝扭转能力与形成和维持成形末端的能力之间的关系的一个或多个特征。所述导丝在导丝部署期间响应操作者操纵,并且通过使成形的远侧末端能够接收传递的扭转力来提供有效的导航性能。
在一些实施例中,可成形末端允许操作者诸如通过在将导丝装置部署在患者脉管系统内之前使末端手动成形而定制可成形末端。因此,操作者能够根据给定应用的特有的条件和/或偏好来定制远侧末端的成形。导丝装置还被构造成在维持成形末端的同时有效地传递扭矩。本文描述的至少一些实施例包括这样的末端,所述末端能够在整个手术过程中或在多个手术过程中或甚至无限期地维持弯折或弯曲形状,直至受到反作用的再成形力。
具有可成形末端的导丝装置
图1和图2示出了具有有效可成形末端的示例性导丝装置100。图1示出了该装置的侧视图,图2示出了该装置的横截面视图。导丝装置100包括芯102。管104联接到芯102并从与芯102的附接点向远侧延伸。如图所示,芯102的远侧区段延伸到管104中并被管104围绕。在一些实施例中,芯102包括一个或多个逐渐变细的区段,使得芯102能够装配在管104内并延伸到该管中。例如,芯102的远侧区段可以被研磨,以便逐渐变细至远端处的更小直径。在该示例中,芯102和管104在它们相邻并彼此附接的附接点103处具有基本上相似的外径。
管104以允许扭转力从芯102传递到管104并由此进一步通过管104向远侧传递的方式联接到芯102(如,使用粘合剂、钎焊(soldering)和/或焊接(welding))。医用级粘合剂可用于在一个或多个点(如,包括附接点103)将管104联接到芯线102。医用级粘合剂/聚合物也可以用在装置的远端,以形成无创伤覆盖物120。
如下面更详细地解释的,管104被微制造成包括多个切口。切口布置成形成一切口图案,该切口图案可有利地在导丝装置100的远侧末端附近提供有效的可成形性,同时还维持良好的扭转能力。为清楚起见,在图1和图2中未示出切口图案。图3至图8中示出了可用在管104中的切口图案的示例。
在一些实施例中,导丝装置100的近侧区段110向近侧延伸至一长度,该长度为提供足够的导丝长度以递送至目标解剖区域(未示出)所需。近侧区段110通常具有约50cm至300cm(约19.69英寸至118.11英寸)范围内的长度。近侧区段110可具有约0.36mm(约0.014英寸)的直径,或约0.20mm至3.175mm(约0.008英寸至0.125英寸)范围内的直径。芯102的远侧区段112可以逐渐变细至约0.051mm(约0.002英寸)的直径,或者约0.025mm至1.27mm(约0.001英寸至0.050英寸)范围内的直径。在一些实施例中,管104的长度在约3cm至100cm(约1.18英寸至39.37英寸)的范围内。管104可以由超弹性材料(诸如镍钛诺)形成和/或包括所述超弹性材料。可替代地,管104可以由线性弹性材料(如,具有至少约6%的可恢复应变)形成和/或包括所述线性弹性材料。装置的向远侧延伸超过管104的部分(称为末端106)的长度被测量为约0.5cm至5cm,或长度被测量为约1cm至3cm。
在一些实施例中,芯102的远侧区段112逐渐变细为圆形横截面。在其他实施例中,芯102的远侧区段112具有扁平或矩形横截面。远侧区段112还可以具有另一横截面形状,诸如另一多边形形状、卵形形状、不规则形状,或沿着其长度的不同区域处的不同横截面形状的组合。
通常,使用者将通过手动弯折、扭曲或以其他方式将导丝装置100的远端(约)1cm至3cm处理成期望形状来成形导丝装置100的远端。图示的导丝装置100包括远侧末端106,该远侧末端向远侧延伸超过管104。末端106被构造成可成形的,使得操作者可以手动地弯折、扭曲或以其他方式将末端106处理成期望的形状。在一些实施例中,末端106包括由不锈钢、铂和/或其他可成形材料形成的一个或多个可成形部件。在优选实施例中,末端106包括由显示出加工硬化特性的材料形成的一个或多个部件,使得末端在成形(即,塑性变形)时在成形区段提供比成形之前更高的弹性模量。
内部线圈114部分地定位于管104内,位于芯102的远侧区段112的至少一部分上。内部线圈114向远侧延伸超过管104以形成末端106的一部分。内部线圈114优选地由一种或多种不透射线的材料形成,诸如铂族、金、银、钯、铱、锇、钽、钨、铋、镝、钆等等。另外或替代地,线圈114可以至少部分地由不锈钢或由在被使用者弯折或以其他方式处理之后能有效地保持形状的其他材料形成。
在所示实施例中,内部线圈114设置在装置的远端处或其附近,并且朝向附接点103向近侧延伸一段距离。在所示装置中,内部线圈114的大部分长度向远侧延伸超出管104。在其他实施例中,内部线圈114可以向近侧进一步地延伸。内部线圈114可以从远端延伸1cm、2cm、4cm、6cm、8cm、10cm、12cm、15cm、20cm、25cm、30cm或35cm,或者可以延伸由前述值中的任何两个值限定的范围中的一段距离。
在一些实施例中,内部线圈114的向远侧延伸超过管104的区段可以由与内部线圈114的更近侧区段不同的材料形成。例如,内部线圈114的远侧区段可以由不锈钢,和/或首选提供有效可成形性的其他材料形成,而内部线圈114的近侧区段由铂或首选用来提供有效射线不透性的其他材料形成。在一些实施例中,内部线圈114形成为一个整体件。在其他实施例中,内部线圈114包括彼此相邻定位和/或通过相互交织的线圈互锁的多个独立区段。另外或替代地,这些独立区段可以钎焊、粘附或以其他方式彼此紧固以形成完整的内部线圈114。
尽管所示实施例示出了内部线圈114的外表面与管104的内表面之间的空间,但是应该理解,这是为了便于可视性而示意性地示出的。在一些实施例中,内部线圈114的尺寸设计成充塞芯102与管104之间的较大比例的空间。例如,内部线圈114的尺寸可以设计成既紧靠芯102的外表面也紧靠管104的内表面。一些实施例可以包括用于导丝装置100的至少一部分区段的在芯102与管104之间的空间,管104和芯102在此处共同延伸。
内部线圈114的设置在管104内的部分可以有利地用于填塞芯102与管104之间的空间,以使芯102的远侧区段112的曲率与管104的曲率一致(align with,对准)。例如,当在管104中形成曲率时,紧密填塞的内部线圈114的区段用作管104与远侧区段112之间的填塞物,以赋予远侧区段112相同的曲率。相反,省却了这种填塞物的导丝装置的芯可以不遵循与管相同的弯曲,而是可以延伸直到抵靠管的内表面,之后被迫弯曲。
如图所示,末端106比管104更向远侧延伸。所示的构造有利地允许末端106相对于管104和导丝100的其余部分成形为期望的位姿(position)并且在成形位姿保持足够长的时间段。与依赖于管的可成形性或依赖于更完全地布置在管内的可成形部件的导丝装置相比,所示的末端106能够维持成形构造而不受管104自身施加的反作用力。
另外,如下面更全面地描述的,管104可以包括切口图案,该切口图案维持有效的扭转能力,同时还在管104的远侧区域处提供足够的柔性,以避免破坏末端106的定制形状。在优选实施例中,芯的可成形远侧区段具有刚度,该刚度能经受作用于芯的成形后的远侧区段的来自管的预期弯折力。在一些实施例中,芯的可成形远侧区段由提供比用于形成管的材料的弹性模量大了约1.5至4倍或约2至3倍的弹性模量的材料或材料组合形成。
与所示实施例相反,依赖于管的成形来提供期望的远侧末端形状的导丝装置将不能够保持成形构造或者仅能够在相对较短的时间段内保持成形构造。因为管结构通常由镍钛诺或其他超弹性材料形成,所以对成形末端的这种退化作用至少部分地发生。这些管在弯折或成形时将被偏向其原始(如,直的)位姿,并将对任何可成形的内部部件施加恢复力,导致末端的变形和定制形状的损失。
通常,例如,在远侧终止于管结构或者另外基本上依赖于管结构的弯折以使末端成形的导丝将在部署之前具有成形末端。然而,在使用导丝期间,成形末端将丢失或退化,因为超弹性管朝向与期望的末端形状相反的其原始形状折曲。相比之下,本文描述的实施例提供了末端可成形的能力,而不会使导丝装置的相邻部件受到变形恢复力。
在所示的导丝装置100中,外部线圈118置于内部线圈114的向远侧延伸的区段之上。内部线圈114和外部线圈118可以使用相似或不相似的线圈特征(线圈线直径、间距等)。通常,外部线圈118由与内部线圈114的线直径相比更大的直径线圈线形成。外部线圈118可以由不锈钢或其他能提供合适的可成形性的合适的材料形成。在一些情况中,外部线圈118由比镍钛诺更为塑性可变形的材料形成。
切口图案
图3至图8示出了可以在本文描述的一个或多个导丝装置实施例中使用的管切口图案的示例性实施例。例如,可以根据图3至图8中所示的一种或多种构造来切割图1和图2中所示实施例的管104。
本文根据设置在每对相邻的周向延伸环之间的轴向延伸梁的数目来命名切口图案。图3和图4示出了“单梁”切口图案,图5和图6示出了“双梁”切口图案,图7示出了“三梁”切口图案。其他实施例可以在每对相邻环之间包括多于三个梁(如,四梁切口图案,五梁切口图案等)。
图3中所示的管结构304包括设置在每对相邻环334之间的单个梁332。成对的相邻梁可以交替180度,如图所示。附加地或替代地,区段可以包括沿着管的长度定位在单侧上的梁,如由图4的管404的梁432和环434所示。
图5中所示的管结构504包括设置在每对相邻环534之间的一对周向相对的梁532。每对梁中的相应梁532可以对称地沿周向间隔开(即,大约180度),如图5所示。替代地,相应的梁可以是周向非对称的,如由图6的管604的梁632和环634所示。图7中所示的管结构704包括设置在每对相邻环734之间的三元组(a triad of,三个一组)的梁732。如图所示,每个三元组中的相应梁可以对称地周向间隔开(即,大约120度),或者可以根据一些非对称布局来定位。
通常,每对相邻环之间留下的梁的数量越多,管的刚度就越大。因此,可以选择切口图案以沿着管的长度提供所需的柔性轮廓(profile)。切割间隔、宽度和/或深度也可以改变,以提供所需的柔性特性。例如,一种管构造可包括具有相对较低柔性和相对较高扭转能力的近侧区段,其快速进展为具有相对较高柔性和相对较低扭转能力的远侧区段(例如,窗孔限定具有切口的切口图案,切口具有朝向管结构的远端增加的深度和/或在连续切口之间具有朝向管结构的远端减小的间隔)。有利地,由这种切口图案提供的柔性可以阻止或最小化管导致导丝(如,芯)的内部结构的形状变形,使得可以更好地形成和维持末端的定制形状。
具有基本上周向等距间隔的梁的双梁切口图案的管的一区段(如图5中所示)通常具有相对较高的传递扭矩的能力和相对较低的柔性,而具有非对称间隔梁的管的区段(如图6所示)的扭矩传递性和柔性通常在对称间隔梁图案与单梁图案之间。对应的一对梁定位得周向对称性越小,所得到的梁将在周向上越靠近,因此该非对称双梁切口图案将与单梁切口图案越相似。因此,这种非对称双梁图案可以用作对称双梁图案与单梁图案之间的过渡。
切口图案可以沿着管的长度形成重复结构单元的“段”。在典型的单梁实施例中,单个段可以被限定为设置在两个相邻环334(一个近侧环和一个远侧环)之间的第一梁332和从远侧环延伸并且相对于第一梁332旋转偏移大约180度的第二相对梁332。类似地,在典型的双梁实施例中,单个段可以被限定为设置在两个相邻环534(一个近侧环和一个远侧环)之间的第一对梁532,以及从远侧环延伸并且相对于第一对梁旋转偏移大约90度的第二对梁532。类似地,在典型的三梁实施例中,单个段可以被限定为设置在两个相邻环734(一个近侧环和一个远侧环)之间的第一三元组梁732和从远侧环延伸并且相对于第一三元组梁旋转偏移约60度的第二三元组梁732。
图8示出了具有多个梁832和环834的管804。所示的切口图案包括在管804的每个连续段处施加的旋转偏移,以使得管中的优选弯折方向最小化。当用在本文中时,“旋转偏移”是两个相邻段之间的角度旋转。因此,从一个段到下一个段应用旋转偏移,甚至是一段内各个切口也可以彼此偏移。
如图所示,切口可以布置成从一个段到下一个段形成基本一致的旋转偏移。所示的切口图案示出了从一个段到下一个段约5度的旋转偏移。当形成具有这种角度偏移的多个连续段时,沿着管804的足够长度所形成的梁的图案以连续旋转的螺旋图案围绕管804的轴线缠绕。角度偏移可以是大约5度、15度、30度、45度、60度、75度、80度或85度。在一些实施例中,在每个连续的段处应用角度偏移。在其他实施例中,多个连续的段没有偏移地彼此相邻设置,之后施加角度偏移。
所示示例示出了具有一系列旋转偏移的双梁切口图案。然而,应该理解的是,相同的原理可以应用于其他切口图案,诸如每对相邻环中具有单梁切口图案、三梁切口图案,或具有多于三个梁的切口图案。在优选实施例中,沿给定区段的长度的每个连续切口或切口组(如,每第二切口、每第三切口、每第四切口等)旋转偏移约1度、2度、3度、5度或10度,或者在单梁图案中从180度偏移约1度、2度、3度、5度或10度,在双梁图案中从90度偏移1度、2度、3度、5度或10度,在三梁图案中从60度偏移1度、2度、3度、5度或10度,对于具有更多梁数量的图案以此类推。这些旋转偏移值有利地示出消除折曲偏差的良好能力。
可以组合图3至图8中所示的切口图案的单独部件和特征以形成不同的管构造。例如,一些管可以构造成具有过渡到单梁切口区段的双梁切口区段。
末端变型例
图9至图11示出了可与本文所述的一个或多个实施例一起使用的各种远侧末端构造的实施例。图9示出了连续直径末端构造。在围绕逐渐变细的芯902的线圈918处具有基本上连续的直径。图10示出了阶梯式末端构造,其中定位在芯1002上方的外部线圈1018具有基本上连续的直径。较小直径的内部线圈1014定位成比外部线圈1018更向远侧延伸,以提供末端直径的阶梯式变化。图11示出了逐渐变细的末端构造,其中线圈1118逐渐变细,以匹配芯1102的至少一部分锥部。图9至图11中所示的末端实施例可以与本文所述的任何导丝装置实施例组合。例如,可以选择期望的末端构造,以便为给定的导丝应用提供期望的可成形性和/或柔性特性。
本文使用的术语“大约”、“约”和“基本上”表示接近所述量或条件的量或条件,其仍然执行期望的功能或实现期望的结果。例如,术语“大约”、“约”和“基本上”可以指从所述量或条件偏离小于10%,或小于5%,或小于1%,或小于0.1%,或小于0.01%的量或条件。
关于本文描绘和/或描述的任何实施例所描述的元件可以与关于本文描绘和/或描述的任何其他实施例所描述的元件组合。例如,关于图3至图8中的任一个的管区段所描述的任何元件和/或关于图9至图11中的任一个的末端构造所描述的任何元件可以相组合,并且与图1和图2的导丝装置一同使用。在任何前述组合中,芯线的远侧末端可以是圆形的、扁平的或其他形状。
在不脱离本发明的构思或基本特征的情况下,本发明可以以其他形式实施。所描述的实施例在所有方面都应被视为仅是说明性的而非限制性的。因此,本发明的范围由所附权利要求而不是前面的描述表示。落在权利要求的含义和等同范围内的所有变化都包括在其范围内。

Claims (16)

1.一种具有可成形末端的导丝装置,所述导丝装置包括:
芯,所述芯具有近侧区段和远侧区段,所述远侧区段具有比所述近侧区段小的直径;
管结构,所述管结构联接到所述芯,以使得所述芯的远侧区段进入所述管结构并向远侧超过所述管结构之外以形成可成形末端;以及
一个或多个线圈,所述一个或多个线圈包裹所述可成形末端的至少一部分,所述一个或多个线圈包括联接到所述管结构的远端并且从所述管结构向远侧延伸的外部线圈,所述一个或多个线圈包括内部线圈,所述内部线圈至少部分地设置在所述管结构内,位于所述芯的所述远侧区段的至少一部分上,其中所述内部线圈的大部分长度向远侧延伸超出所述管结构以形成所述可成形末端的至少一部分,其中,所述外部线圈包裹所述内部线圈的向远侧延伸超过所述管结构的至少一部分,并且其中所述内部线圈至少部分地由在被使用者弯折或以其他方式处理之后能有效地保持形状的材料形成,并且其中所述内部线圈的尺寸设计成既紧靠所述芯的外表面也紧靠所述管结构的内表面,使得所述内部线圈的尺寸和形状被构造为填塞所述芯与所述管结构之间的空间,使得当所述管结构中形成曲率时,所述内部线圈将相同的曲率赋予所述芯的重合部分。
2.根据权利要求1所述的导丝装置,其中,所述芯的远侧区段从所述芯的近侧区段逐渐变细。
3.根据权利要求1所述的导丝装置,其中,所述可成形末端向远侧延伸超过所述管结构0.5cm至5cm的距离,或1cm至3cm的距离。
4.根据权利要求1所述的导丝装置,其中,所述外部线圈由比镍钛诺更为塑性可变形的材料形成。
5.根据权利要求4所述的导丝装置,其中,所述外部线圈由不锈钢形成。
6.根据权利要求1所述的导丝装置,其中,所述内部线圈由不透射线的材料形成。
7.根据权利要求6所述的导丝装置,其中,所述内部线圈由铂形成。
8.根据权利要求1所述的导丝装置,其中,所述管结构由镍钛诺形成。
9.根据权利要求1所述的导丝装置,其中,所述芯由不锈钢形成。
10.根据权利要求1所述的导丝装置,其中,所述管结构包括多个窗孔,所述多个窗孔限定与多个周向延伸的环联接的多个轴向延伸的梁。
11.根据权利要求10所述的导丝装置,其中,所述多个窗孔被布置成单梁切口图案、双梁切口图案或三梁切口图案中的一种或多种。
12.根据权利要求10所述的导丝装置,其中,所述窗孔限定具有旋转偏移的切口图案,使得沿着所述管结构的长度的每个连续段自前一段周向旋转。
13.根据权利要求10所述的导丝装置,其中,所述窗孔限定具有切口的切口图案,所述切口具有朝向所述管结构的远端增加的深度和/或在连续切口之间具有朝向所述管结构的远端减小的间隔。
14.一种具有可成形末端的导丝装置,所述导丝装置包括:
芯,所述芯具有近侧区段和远侧区段,所述远侧区段具有比所述近侧区段小的直径;
管结构,所述管结构联接到所述芯,以使得所述芯的远侧区段进入所述管结构并向远侧超过所述管结构之外以形成可成形末端,其中所述管结构包括多个窗孔,所述窗孔限定多个轴向延伸的梁和周向延伸的环;
内部线圈,所述内部线圈包裹所述芯的远侧区段的至少一部分,所述内部线圈的一部分设置在所述芯的外表面与所述管结构的内表面之间,并且所述内部线圈的大部分向远侧延伸超过所述管结构以形成所述可成形末端的至少一部分,其中所述内部线圈至少部分地由在被使用者弯折或以其他方式处理之后能有效地保持形状的材料形成,其中所述内部线圈的尺寸被设计为既紧靠所述芯的外表面也紧靠所述管结构的内表面,使得所述内部线圈的尺寸和形状被构造为填塞所述芯与所述管结构之间的空间,使得当所述管结构中形成曲率时,所述内部线圈将相同的曲率赋予所述芯的重合部分;以及
外部线圈,所述外部线圈联接到所述管结构的远端并从所述管结构向远侧延伸,所述外部线圈包裹所述内部线圈的向远侧延伸超过所述管结构的部分。
15.根据权利要求14所述的导丝装置,其中,所述内部线圈和所述外部线圈构造成使得所述芯在所述可成形末端处不经受主导恢复力。
16.一种使用具有可成形末端的导丝装置的方法,该方法包括:
提供导丝装置,所述导丝装置包括:
芯,所述芯具有近侧区段和远侧区段,所述远侧区段具有比所述近侧区段小的直径,
管结构,所述管结构联接到所述芯,以使得所述芯的远侧区段进入所述管结构并向远侧超过所述管结构之外以形成可成形末端,其中所述管结构包括多个窗孔,所述窗孔限定多个轴向延伸的梁和周向延伸的环;
内部线圈,所述内部线圈包裹所述芯的远侧区段的至少一部分,所述内部线圈的一部分设置在所述芯的外表面与所述管结构的内表面之间,并且所述内部线圈的大部分向远侧延伸超过所述管结构以形成所述可成形末端的至少一部分,其中所述内部线圈至少部分地由在被使用者弯折或以其他方式处理之后能有效地保持形状的材料形成,其中所述内部线圈的尺寸被设计为既紧靠所述芯的外表面也紧靠所述管结构的内表面,使得所述内部线圈的尺寸和形状被构造为填塞所述芯与所述管结构之间的空间,使得当所述管结构中形成曲率时,所述内部线圈将相同的曲率赋予所述芯的重合部分,及
外部线圈,所述外部线圈联接到所述管结构的远端并从所述管结构向远侧延伸,所述外部线圈包裹所述内部线圈的向远侧延伸超过所述管结构的部分;以及
成形所述可成形末端。
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Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10363389B2 (en) 2009-04-03 2019-07-30 Scientia Vascular, Llc Micro-fabricated guidewire devices having varying diameters
US11406791B2 (en) 2009-04-03 2022-08-09 Scientia Vascular, Inc. Micro-fabricated guidewire devices having varying diameters
US8468919B2 (en) 2008-12-08 2013-06-25 Next Vascular, Llc Micro-cutting machine for forming cuts in products
US11207502B2 (en) 2016-07-18 2021-12-28 Scientia Vascular, Llc Guidewire devices having shapeable tips and bypass cuts
US11052228B2 (en) 2016-07-18 2021-07-06 Scientia Vascular, Llc Guidewire devices having shapeable tips and bypass cuts
US10821268B2 (en) 2016-09-14 2020-11-03 Scientia Vascular, Llc Integrated coil vascular devices
US11452541B2 (en) 2016-12-22 2022-09-27 Scientia Vascular, Inc. Intravascular device having a selectively deflectable tip
KR102628519B1 (ko) 2017-05-26 2024-01-22 사이언시아 바스큘라, 아이엔씨. 비나선형 절개부 구조를 가지는 미세 제조 의료 장치
US11305095B2 (en) 2018-02-22 2022-04-19 Scientia Vascular, Llc Microfabricated catheter having an intermediate preferred bending section
CN112236187B (zh) * 2018-03-09 2022-12-20 血管科学公司 具有能成形末端和旁路切口的导丝装置
US20200222672A1 (en) * 2019-01-15 2020-07-16 Scientia Vascular Guidewire with core centering mechanism
CA3167908A1 (en) 2019-04-05 2020-10-08 Traverse Vascular, Inc. Reentry catheters for traversing chronic total occlusions
JP7260408B2 (ja) * 2019-06-14 2023-04-18 株式会社パイオラックスメディカルデバイス スリットパイプ及びそれを用いたガイドワイヤ
US11918298B2 (en) * 2019-09-12 2024-03-05 Biosense Webster (Israel) Ltd. Very narrow probe with coil
US11478609B2 (en) * 2019-09-26 2022-10-25 Biosense Webster (Israel) Ltd. Bendable guidewire
US20210228845A1 (en) * 2020-01-23 2021-07-29 Scientia Vascular, Llc Guidewire having enlarged, micro-fabricated distal section
JPWO2021230151A1 (zh) 2020-05-11 2021-11-18
KR102247637B1 (ko) 2020-07-10 2021-05-03 주식회사 레노메디컬 전해연마식 카테터 안내선의 코어 와이어 및 코어 와이어 전해연마 장치
CN113041159A (zh) * 2021-03-23 2021-06-29 昆明医科大学第二附属医院 一种便于置入幽门的新型胃管
WO2023080052A1 (ja) 2021-11-02 2023-05-11 国立大学法人神戸大学 ポリウレタンの製造方法

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5345945A (en) * 1990-08-29 1994-09-13 Baxter International Inc. Dual coil guidewire with radiopaque distal tip
US20040181174A2 (en) * 2002-07-25 2004-09-16 Precision Vascular Systems, Inc. Medical device for navigation through anatomy and method of making same
US20090177119A1 (en) * 2008-01-03 2009-07-09 Boston Scientific Scimed, Inc. Articulating intracorporeal medical device
US20100318066A1 (en) * 2009-06-16 2010-12-16 Asahi Intecc Co., Ltd. Medical guidewire
CN102049085A (zh) * 2009-10-27 2011-05-11 加藤富久 医疗引导线、制造医疗引导线的方法、与医疗引导线组合的微管和引导管的组件
CN102107041A (zh) * 2009-12-25 2011-06-29 朝日英达科株式会社 导线
US20140276109A1 (en) * 2013-03-15 2014-09-18 Boston Scientific Scimed, Inc. Pressure sensing guidewire
US20160199620A1 (en) * 2015-01-09 2016-07-14 Mivi Neuroscience Inc. Medical guidewires for tortuous vessels

Family Cites Families (377)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2022065A (en) 1932-07-07 1935-11-26 Frederick C Wappler Therapeutic applicator device
US2187299A (en) 1935-08-13 1940-01-16 Burkhardt Otto Wilhelm Dressing of individual blocks of stone
US3183702A (en) 1960-11-21 1965-05-18 Rca Corp Method of and apparatus for cutting and deburring tubes
US3612058A (en) 1968-04-17 1971-10-12 Electro Catheter Corp Catheter stylets
US3572334A (en) 1968-11-27 1971-03-23 Johnson & Johnson Intravenous catheter placement unit
JPS4845313Y1 (zh) 1969-08-06 1973-12-26
JPS485208Y1 (zh) 1970-07-28 1973-02-09
US3920058A (en) 1971-02-22 1975-11-18 Willard H Walker Method of sawing logs
US3709271A (en) 1971-07-01 1973-01-09 Mc Farland L Co Method and apparatus for deep incising poles
US4163406A (en) 1977-12-15 1979-08-07 Genevieve I. Hanscom Centering device for feeding articles to a food slicer
US4239069A (en) 1979-08-10 1980-12-16 Zimmerman Edwin H Automatic cant production machine
SE419059B (sv) 1980-07-03 1981-07-13 Kockums Ind Ab Styranordning vid sagbladets forsedda sonderdelningsmaskiner for virke
US5506682A (en) 1982-02-16 1996-04-09 Sensor Adaptive Machines Inc. Robot vision using targets
JPS59102509A (ja) 1983-11-21 1984-06-13 Fujikawa Seikou Kk 複動多頭式穿孔摺割切削加工装置
US4801297A (en) 1984-06-01 1989-01-31 Edward Weck Incorporated Catheter having slit tip
KR900001232B1 (ko) 1984-12-27 1990-03-05 가부시끼 가이샤 디스코 반도체 웨이퍼 방형절단기
US5102390A (en) 1985-05-02 1992-04-07 C. R. Bard, Inc. Microdilatation probe and system for performing angioplasty in highly stenosed blood vessels
US4719924A (en) 1986-09-09 1988-01-19 C. R. Bard, Inc. Small diameter steerable guidewire with adjustable tip
US4989608A (en) 1987-07-02 1991-02-05 Ratner Adam V Device construction and method facilitating magnetic resonance imaging of foreign objects in a body
US4846186A (en) 1988-01-12 1989-07-11 Cordis Corporation Flexible guidewire
US4895168A (en) 1988-01-21 1990-01-23 Schneider (Usa) Inc., A Pfizer Company Guidewire with movable core and external tubular safety cover
US5507751A (en) 1988-11-09 1996-04-16 Cook Pacemaker Corporation Locally flexible dilator sheath
US5372587A (en) 1989-01-09 1994-12-13 Pilot Cariovascular Systems, Inc. Steerable medical device
US5047045A (en) 1989-04-13 1991-09-10 Scimed Life Systems, Inc. Multi-section coaxial angioplasty catheter
US5144959A (en) * 1989-08-15 1992-09-08 C. R. Bard, Inc. Catheter guidewire with varying radiopacity
US5084022A (en) 1989-10-04 1992-01-28 Lake Region Manufacturing Company, Inc. Graduated guidewire
US5095915A (en) 1990-03-19 1992-03-17 Target Therapeutics Guidewire with flexible distal tip
US5147317A (en) 1990-06-04 1992-09-15 C.R. Bard, Inc. Low friction varied radiopacity guidewire
US5069217A (en) 1990-07-09 1991-12-03 Lake Region Manufacturing Co., Inc. Steerable guide wire
DE69124395T2 (de) 1990-11-09 1997-08-28 Boston Scient Corp Führungsdraht zum durchqueren von okklusionen in blutgefässen
US5174302A (en) 1990-12-04 1992-12-29 Cordis Corporation Variable radiopacity guidewire with spaced highly radiopaque regions
AU660444B2 (en) 1991-02-15 1995-06-29 Ingemar H. Lundquist Torquable catheter and method
US5315996A (en) 1991-02-15 1994-05-31 Lundquist Ingemar H Torquable catheter and method
US5454787A (en) 1991-02-15 1995-10-03 Lundquist; Ingemar H. Torquable tubular assembly and torquable catheter utilizing the same
US5154725A (en) 1991-06-07 1992-10-13 Advanced Cardiovascular Systems, Inc. Easily exchangeable catheter system
CA2117088A1 (en) 1991-09-05 1993-03-18 David R. Holmes Flexible tubular device for use in medical applications
US6027863A (en) 1991-09-05 2000-02-22 Intratherapeutics, Inc. Method for manufacturing a tubular medical device
US5741429A (en) 1991-09-05 1998-04-21 Cardia Catheter Company Flexible tubular device for use in medical applications
US5437288A (en) 1992-09-04 1995-08-01 Mayo Foundation For Medical Education And Research Flexible catheter guidewire
IL106946A0 (en) 1992-09-22 1993-12-28 Target Therapeutics Inc Detachable embolic coil assembly
US5382259A (en) 1992-10-26 1995-01-17 Target Therapeutics, Inc. Vasoocclusion coil with attached tubular woven or braided fibrous covering
JP3114908B2 (ja) 1992-11-16 2000-12-04 三菱電線工業株式会社 剛性傾斜トルクチューブ、その製造方法およびそのトルクチューブを用いてなるカテーテル
US5441483A (en) 1992-11-16 1995-08-15 Avitall; Boaz Catheter deflection control
US5326374A (en) 1992-12-01 1994-07-05 Michael N. Ilbawi Body-implantable device for controlling the size of a fluid passageway
US5358493A (en) 1993-02-18 1994-10-25 Scimed Life Systems, Inc. Vascular access catheter and methods for manufacture thereof
US7883474B1 (en) 1993-05-11 2011-02-08 Target Therapeutics, Inc. Composite braided guidewire
JP3383009B2 (ja) 1993-06-29 2003-03-04 テルモ株式会社 血管カテーテル
CA2102250A1 (en) * 1993-11-02 1995-05-03 Robert S. Schwartz Flexible catheter guidewire
JPH09507399A (ja) 1993-11-12 1997-07-29 マイクロ インターベンショナル システムズ 直径が小さく、かつトルクが高いカテーテル
EP0732954B1 (en) 1993-12-10 1998-08-19 Schneider (Usa) Inc. Guiding catheter
US5569218A (en) 1994-02-14 1996-10-29 Scimed Life Systems, Inc. Elastic guide catheter transition element
US5911715A (en) 1994-02-14 1999-06-15 Scimed Life Systems, Inc. Guide catheter having selected flexural modulus segments
US5606981A (en) 1994-03-11 1997-03-04 C. R. Bard, Inc. Catheter guidewire with radiopaque markers
US5673707A (en) 1994-09-23 1997-10-07 Boston Scientific Corporation Enhanced performance guidewire
US5554114A (en) 1994-10-20 1996-09-10 Micro Therapeutics, Inc. Infusion device with preformed shape
ATE186653T1 (de) 1994-12-15 1999-12-15 Schneider Europ Gmbh Katheter
ES2148362T3 (es) 1995-03-02 2000-10-16 Schneider Europ Gmbh Metodo para fabricar un alambre guia.
JPH08308934A (ja) 1995-05-22 1996-11-26 Piolax Inc 医療用のチューブ
US5551444A (en) 1995-05-31 1996-09-03 Radius Medical Technologies, Inc. Flexible guidewire with radiopaque outer coil and non-radiopaque inner coil
US5746701A (en) 1995-09-14 1998-05-05 Medtronic, Inc. Guidewire with non-tapered tip
US5997487A (en) 1995-10-11 1999-12-07 Micro Therapeutics, Inc. Infusion wire having fixed core wire
US5833632A (en) 1995-12-07 1998-11-10 Sarcos, Inc. Hollow guide wire apparatus catheters
US20030069522A1 (en) 1995-12-07 2003-04-10 Jacobsen Stephen J. Slotted medical device
US6428489B1 (en) 1995-12-07 2002-08-06 Precision Vascular Systems, Inc. Guidewire system
US5931830A (en) 1995-12-07 1999-08-03 Sarcos L.C. Hollow coil guide wire apparatus for catheters
US5659205A (en) 1996-01-11 1997-08-19 Ebara International Corporation Hydraulic turbine power generator incorporating axial thrust equalization means
US6004279A (en) 1996-01-16 1999-12-21 Boston Scientific Corporation Medical guidewire
US5573867A (en) 1996-01-31 1996-11-12 Westinghouse Electric Corporation Purge gas protected transportable pressurized fuel cell modules and their operation in a power plant
US6436056B1 (en) 1996-02-28 2002-08-20 Boston Scientific Corporation Polymeric implements for torque transmission
US5792154A (en) 1996-04-10 1998-08-11 Target Therapeutics, Inc. Soft-ended fibered micro vaso-occlusive devices
US5690120A (en) 1996-05-24 1997-11-25 Sarcos, Inc. Hybrid catheter guide wire apparatus
US6440088B1 (en) 1996-05-24 2002-08-27 Precision Vascular Systems, Inc. Hybrid catheter guide wire apparatus and method
US5916194A (en) 1996-05-24 1999-06-29 Sarcos, Inc. Catheter/guide wire steering apparatus and method
US6017319A (en) 1996-05-24 2000-01-25 Precision Vascular Systems, Inc. Hybrid tubular guide wire for catheters
US5833631A (en) 1996-06-28 1998-11-10 Target Therapeutics, Inc. Fiber tip guidewire
JP3223421B2 (ja) 1996-08-13 2001-10-29 株式会社東京精密 ダイシング装置
US6553880B2 (en) 1996-09-16 2003-04-29 Sarcos, Lc Micromachining system
US6014919A (en) 1996-09-16 2000-01-18 Precision Vascular Systems, Inc. Method and apparatus for forming cuts in catheters, guidewires, and the like
AUPO251096A0 (en) 1996-09-23 1996-10-17 Cardiac Crc Nominees Pty Limited Polysiloxane-containing polyurethane elastomeric compositions
US5685568A (en) 1996-11-04 1997-11-11 Pirrello; Roberta Protective holder and display apparatus for business cards
US6251086B1 (en) 1999-07-27 2001-06-26 Scimed Life Systems, Inc. Guide wire with hydrophilically coated tip
US5911717A (en) 1997-03-17 1999-06-15 Precision Vascular Systems, Inc. Catheter deliverable thrombogenic apparatus and method
US5800454A (en) 1997-03-17 1998-09-01 Sarcos, Inc. Catheter deliverable coiled wire thromboginic apparatus and method
US5876356A (en) 1997-04-02 1999-03-02 Cordis Corporation Superelastic guidewire with a shapeable tip
EP0879616A1 (en) 1997-05-21 1998-11-25 Schneider (Europe) GmbH Guide wire
US7494474B2 (en) 1997-06-04 2009-02-24 Advanced Cardiovascular Systems, Inc. Polymer coated guidewire
EP0988081A1 (en) 1997-06-04 2000-03-29 Advanced Cardiovascular Systems, Inc. Steerable guidewire with enhanced distal support
US6183420B1 (en) 1997-06-20 2001-02-06 Medtronic Ave, Inc. Variable stiffness angioplasty guide wire
US7037316B2 (en) 1997-07-24 2006-05-02 Mcguckin Jr James F Rotational thrombectomy device
JP3748511B2 (ja) 1997-09-29 2006-02-22 ボストン・サイエンティフィック・サイメド・インコーポレイテッド 画像ガイドワイヤ
US6056702A (en) 1998-10-02 2000-05-02 Cordis Corporation Guidewire with outer sheath
JP3203364B2 (ja) 1997-12-01 2001-08-27 株式会社東京精密 アライメント方法及びその装置
US6033394A (en) 1997-12-05 2000-03-07 Intratherapeutics, Inc. Catheter support structure
US6110164A (en) 1997-12-05 2000-08-29 Intratherapeutics, Inc. Guideless catheter segment
US6168570B1 (en) 1997-12-05 2001-01-02 Micrus Corporation Micro-strand cable with enhanced radiopacity
US6022369A (en) 1998-02-13 2000-02-08 Precision Vascular Systems, Inc. Wire device with detachable end
US6346091B1 (en) 1998-02-13 2002-02-12 Stephen C. Jacobsen Detachable coil for aneurysm therapy
US6824550B1 (en) 2000-04-06 2004-11-30 Norbon Medical, Inc. Guidewire for crossing occlusions or stenosis
US20060074442A1 (en) 2000-04-06 2006-04-06 Revascular Therapeutics, Inc. Guidewire for crossing occlusions or stenoses
US6245030B1 (en) 1998-03-04 2001-06-12 C. R. Bard, Inc. Flexible kink resistant, low friction guidewire with formable tip, and method for making same
US20060047223A1 (en) 2004-08-31 2006-03-02 Ryan Grandfield Apparatus and method for joining stainless steel guide wire portion to nitinol portion, without a hypotube
JP3988156B2 (ja) 1998-04-10 2007-10-10 Nskワーナー株式会社 弾性チューブ式ブレーキバンド
US6132389A (en) 1998-04-23 2000-10-17 Advanced Cardiovascular Systems, Inc. Proximally tapered guidewire tip coil
US6306105B1 (en) 1998-05-14 2001-10-23 Scimed Life Systems, Inc. High performance coil wire
CA2345921C (en) 1998-06-12 2005-01-25 Cardiac Pacemakers, Inc. Modified guidewire for left ventricular access lead
US6139511A (en) 1998-06-29 2000-10-31 Advanced Cardiovascular Systems, Inc. Guidewire with variable coil configuration
AU2004201816B2 (en) 1998-07-08 2006-12-07 Ams Research Corporation Occluding Device and Method of Use
US6022343A (en) 1998-09-03 2000-02-08 Intratherapeutics, Inc. Bridged coil catheter support structure
JP2000116787A (ja) 1998-10-16 2000-04-25 Piolax Inc 医療用チューブ
JP3645107B2 (ja) 1998-10-27 2005-05-11 テルモ株式会社 医療用チューブ
US6033288A (en) 1998-10-29 2000-03-07 Kulicke & Soffa Investments, Inc. Monitoring system for dicing saws
US6214042B1 (en) 1998-11-10 2001-04-10 Precision Vascular Systems, Inc. Micro-machined stent for vessels, body ducts and the like
US6063101A (en) 1998-11-20 2000-05-16 Precision Vascular Systems, Inc. Stent apparatus and method
US6228073B1 (en) 1998-12-15 2001-05-08 Medtronic, Inc. Angiography luer hub having wings proximal to the plurality of grips and strain relief
US6402706B2 (en) 1998-12-30 2002-06-11 Advanced Cardiovascular Systems, Inc. Guide wire with multiple polymer jackets over distal and intermediate core sections
US6179828B1 (en) 1999-03-19 2001-01-30 Merit Medical Systems, Inc. Infusion system with fixed occluding wire
US6302870B1 (en) 1999-04-29 2001-10-16 Precision Vascular Systems, Inc. Apparatus for injecting fluids into the walls of blood vessels, body cavities, and the like
WO2000066211A1 (fr) 1999-04-30 2000-11-09 Usaminanotechnology, Inc. Catheter a fil-guide
US6183410B1 (en) 1999-05-06 2001-02-06 Precision Vascular Systems, Inc. Radiation exposure device for blood vessels, body cavities and the like
JP3623896B2 (ja) 1999-05-29 2005-02-23 功 吉田 板材の溝加工機
US6458867B1 (en) 1999-09-28 2002-10-01 Scimed Life Systems, Inc. Hydrophilic lubricant coatings for medical devices
US7018406B2 (en) 1999-11-17 2006-03-28 Corevalve Sa Prosthetic valve for transluminal delivery
JP2001145699A (ja) 1999-11-22 2001-05-29 Nissho Corp ガイドワイアー
US20020062524A1 (en) 1999-11-29 2002-05-30 Vogland James H. Mattress and sheet attachment assembly
US6579246B2 (en) * 1999-12-22 2003-06-17 Sarcos, Lc Coronary guidewire system
US6554820B1 (en) 2000-03-08 2003-04-29 Scimed Life Systems, Inc. Composite flexible tube for medical applications
US6494894B2 (en) 2000-03-16 2002-12-17 Scimed Life Systems, Inc. Coated wire
US6602207B1 (en) 2000-07-19 2003-08-05 Scimed Life Systems, Inc. Guide wire stiffness transition element
US6527746B1 (en) 2000-08-03 2003-03-04 Ev3, Inc. Back-loading catheter
ATE287747T1 (de) 2000-10-03 2005-02-15 Cook William Europ Führungsdraht
US7097624B2 (en) 2000-10-05 2006-08-29 Scimed Life Systems, Inc. Multi-layer and multi-section coils for guide wire
US6492615B1 (en) 2000-10-12 2002-12-10 Scimed Life Systems, Inc. Laser polishing of medical devices
US6527732B1 (en) 2000-10-17 2003-03-04 Micro Therapeutics, Inc. Torsionally compensated guidewire
US6544197B2 (en) 2000-10-20 2003-04-08 Radius Medical Technologies, Inc. Composite guidewire
US6685679B2 (en) 2000-12-06 2004-02-03 Scimed Life Systems, Inc. Interlocking metal shaft
US6669652B2 (en) 2000-12-21 2003-12-30 Advanced Cardiovascular Systems, Inc. Guidewire with tapered distal coil
US6558355B1 (en) 2000-12-29 2003-05-06 Ethicon, Inc. Flushable guidewire device
JP2002237472A (ja) 2001-02-07 2002-08-23 Disco Abrasive Syst Ltd 被加工物の切削方法
AU2002253490A1 (en) 2001-04-17 2002-10-28 Salviac Limited A catheter
EP1406536A4 (en) 2001-06-20 2005-09-21 Microvention Inc MEDICAL DEVICES WITH INTEGRAL OR PARTIAL POLYMER SLEEVES AND METHODS OF MAKING
DE60216593T2 (de) 2001-07-05 2007-09-27 Precision Vascular Systems, Inc., West Valley City Medizinische vorrichtung mit drehmoment übertragendem weichem endstück und verfahren zu seiner formgebung
JP2003011117A (ja) 2001-07-05 2003-01-15 Canon Inc 柱状母材の切断方法、柱状母材の切断装置、光を用いたインゴット切断方法、光を用いたインゴット切断装置およびウェーハの製造方法
US6918882B2 (en) 2001-10-05 2005-07-19 Scimed Life Systems, Inc. Guidewire with stiffness blending connection
US7421929B2 (en) 2001-10-11 2008-09-09 Andrew French Drive apparatus
US6652508B2 (en) 2001-11-09 2003-11-25 Scimed Life Systems, Inc. Intravascular microcatheter having hypotube proximal shaft with transition
JP3762290B2 (ja) 2001-12-03 2006-04-05 朝日インテック株式会社 医療用ガイドワイヤ
US7670302B2 (en) 2001-12-18 2010-03-02 Boston Scientific Scimed, Inc. Super elastic guidewire with shape retention tip
US6702762B2 (en) 2001-12-27 2004-03-09 Advanced Cardiovascular Systems, Inc. Apparatus and method for joining two guide wire core materials without a hypotube
DE10213368A1 (de) 2002-03-21 2003-10-02 Biotronik Mess & Therapieg Oberflächenstruktur für eine Kathetergleitfläche
US7128718B2 (en) 2002-03-22 2006-10-31 Cordis Corporation Guidewire with deflectable tip
US7769839B2 (en) 2002-06-21 2010-08-03 International Business Machines Corporation Method and structure for autoconfiguration of overlay networks by automatic selection of a network designated router
JP2004025340A (ja) 2002-06-25 2004-01-29 Toshiba Corp 表面加工方法および装置
US8425549B2 (en) 2002-07-23 2013-04-23 Reverse Medical Corporation Systems and methods for removing obstructive matter from body lumens and treating vascular defects
US7914467B2 (en) 2002-07-25 2011-03-29 Boston Scientific Scimed, Inc. Tubular member having tapered transition for use in a medical device
US20040039371A1 (en) 2002-08-23 2004-02-26 Bruce Tockman Coronary vein navigator
US8465469B2 (en) 2002-09-12 2013-06-18 Medtronic Vascular, Inc. Reinforced catheter and methods of making
US20040087933A1 (en) 2002-09-18 2004-05-06 Lee Jeong S. Stiff guiding catheter liner material
US20040102719A1 (en) 2002-11-22 2004-05-27 Velocimed, L.L.C. Guide wire control catheters for crossing occlusions and related methods of use
US6866642B2 (en) 2002-11-25 2005-03-15 Advanced Cardiovascular Systems, Inc. Enhanced method for joining two core wires
US8133241B2 (en) 2002-12-10 2012-03-13 Battelle Memorial Institute Articulated elements and methods for use
US7077811B2 (en) 2002-12-23 2006-07-18 Scimed Life Systems, Inc. Guidewire tip construction
US8167821B2 (en) 2003-02-26 2012-05-01 Boston Scientific Scimed, Inc. Multiple diameter guidewire
US7182735B2 (en) 2003-02-26 2007-02-27 Scimed Life Systems, Inc. Elongated intracorporal medical device
US20040167437A1 (en) 2003-02-26 2004-08-26 Sharrow James S. Articulating intracorporal medical device
US7276062B2 (en) 2003-03-12 2007-10-02 Biosence Webster, Inc. Deflectable catheter with hinge
US8052694B2 (en) 2003-03-19 2011-11-08 Boston Scientific Scimed, Inc. Device for manipulating material in a tissue
US7001369B2 (en) 2003-03-27 2006-02-21 Scimed Life Systems, Inc. Medical device
US7354442B2 (en) 2003-05-05 2008-04-08 Warsaw Orthopedic, Inc. Bone anchor and methods of using the same
JP2004329552A (ja) 2003-05-07 2004-11-25 Vayu:Kk 薬液投与用カテーテル
US7758520B2 (en) 2003-05-27 2010-07-20 Boston Scientific Scimed, Inc. Medical device having segmented construction
JP4677205B2 (ja) 2003-07-17 2011-04-27 テルモ株式会社 ガイドワイヤ
US20150011834A1 (en) 2003-07-31 2015-01-08 Cook Medical Technologies Llc System and method for introducing multiple medical devices
IES20040535A2 (en) 2003-08-07 2005-02-23 Brivant Res & Dev Ltd A guide wire for use with a catheter
DE602004018331D1 (de) 2003-09-05 2009-01-22 Cook Urological Inc Führungsdraht mit doppelende
US7785273B2 (en) 2003-09-22 2010-08-31 Boston Scientific Scimed, Inc. Guidewire with reinforcing member
CR7129A (es) 2003-10-29 2003-11-17 Carlos Eduardo Rold N Villalobos Metodo y aparato para almacenar gases a baja temperatura utilizando un sistema de recuperacion de refrigeracion
US7867271B2 (en) 2003-11-20 2011-01-11 Advanced Cardiovascular Systems, Inc. Rapid-exchange delivery systems for self-expanding stents
US20050124976A1 (en) 2003-12-04 2005-06-09 Devens Douglas A.Jr. Medical devices
US7747314B2 (en) 2003-12-30 2010-06-29 Boston Scientific Scimed, Inc. Distal assembly for a medical device
CA2558796C (en) 2004-03-23 2016-10-04 Boston Scientific Limited In-vivo visualization system
US20050216049A1 (en) 2004-03-29 2005-09-29 Jones Donald K Vascular occlusive device with elastomeric bioresorbable coating
DE102004023642A1 (de) 2004-05-10 2005-12-08 Restate Patent Ag Katheter-Führungsdraht insbesondere für die perkutane transluminale Coronar-Angioplastik
US7699056B2 (en) 2004-06-10 2010-04-20 Conceptus, Inc. Medical devices and methods of making and using such devices
DE102004028367A1 (de) 2004-06-11 2005-12-29 Biotronik Vi Patent Ag Katheter-Führungsdraht insbesondere für kardio-vaskuläre Eingriffe
EP2198912A1 (en) 2004-08-05 2010-06-23 Cathrx Ltd A steerable catheter
US20060041186A1 (en) 2004-08-17 2006-02-23 Vancaillie Thierry G Continuous flow single sheath for endoscope
US7621904B2 (en) 2004-10-21 2009-11-24 Boston Scientific Scimed, Inc. Catheter with a pre-shaped distal tip
JP4907945B2 (ja) 2004-11-01 2012-04-04 テルモ株式会社 医療用ガイドワイヤ
US7989042B2 (en) 2004-11-24 2011-08-02 Boston Scientific Scimed, Inc. Medical devices with highly flexible coated hypotube
JP4571851B2 (ja) 2004-11-30 2010-10-27 株式会社ディスコ 切削装置
US8333714B2 (en) 2006-09-10 2012-12-18 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
KR20080005433A (ko) 2005-04-20 2008-01-11 쿡 인코포레이티드 의료기기 전달시스템용 조인트
DE102005022688B4 (de) 2005-05-12 2011-06-30 EPflex Feinwerktechnik GmbH, 72581 Führungsdraht für ein medizinisches Instrument
US7370242B2 (en) 2005-05-23 2008-05-06 Network Appliance, Inc. Thermal monitoring and response apparatus and method for computer unit
US7110910B1 (en) 2005-06-13 2006-09-19 The Timken Company Method and apparatus for determining the straightness of tubes and bars
US20070185415A1 (en) 2005-07-07 2007-08-09 Ressemann Thomas V Steerable guide wire with torsionally stable tip
US7623899B2 (en) 2005-09-16 2009-11-24 Biosense Webster, Inc. Catheter with flexible pre-shaped tip section
US20080188928A1 (en) * 2005-09-16 2008-08-07 Amr Salahieh Medical device delivery sheath
US7850623B2 (en) 2005-10-27 2010-12-14 Boston Scientific Scimed, Inc. Elongate medical device with continuous reinforcement member
US8876772B2 (en) 2005-11-16 2014-11-04 Boston Scientific Scimed, Inc. Variable stiffness shaft
US8292827B2 (en) 2005-12-12 2012-10-23 Boston Scientific Scimed, Inc. Micromachined medical devices
US8152839B2 (en) 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US8377056B2 (en) 2005-12-29 2013-02-19 Boston Scientific Scimed, Inc. Method of treating tissue with radio frequency vascular electrode array
US20070167876A1 (en) 2006-01-17 2007-07-19 Euteneuer Charles L Occluding guidewire and methods
US8157837B2 (en) 2006-03-13 2012-04-17 Pneumrx, Inc. Minimally invasive lung volume reduction device and method
US7785317B2 (en) 2006-03-29 2010-08-31 Codman & Shurtleff, Inc. Joined metal tubing and method of manufacture
US7766896B2 (en) 2006-04-25 2010-08-03 Boston Scientific Scimed, Inc. Variable stiffness catheter assembly
US7731669B2 (en) 2006-05-12 2010-06-08 Concert Medical, Llc Guidewire formed with composite construction and method for making the same
US20100114302A1 (en) 2006-07-24 2010-05-06 Abraham Tzafriri Endovascular devices with axial perturbations
US8021311B2 (en) 2006-08-16 2011-09-20 Boston Scientific Scimed, Inc. Mechanical honing of metallic tubing for soldering in a medical device construction
US8728010B2 (en) 2006-08-24 2014-05-20 Boston Scientific Scimed, Inc. Elongate medical device including deformable distal end
US8419658B2 (en) 2006-09-06 2013-04-16 Boston Scientific Scimed, Inc. Medical device including structure for crossing an occlusion in a vessel
WO2008034010A2 (en) 2006-09-13 2008-03-20 Boston Scientific Limited Crossing guidewire
US8518054B2 (en) 2006-11-21 2013-08-27 Boston Scientific Scimed, Inc. Medical retrieval devices
US20080122226A1 (en) 2006-11-29 2008-05-29 Ebara International Corporation Compact assemblies for high efficiency performance of cryogenic liquefied gas expanders and pumps
US8556914B2 (en) 2006-12-15 2013-10-15 Boston Scientific Scimed, Inc. Medical device including structure for crossing an occlusion in a vessel
JP5020630B2 (ja) 2006-12-28 2012-09-05 テルモ株式会社 ガイドワイヤ
JP5148936B2 (ja) 2006-12-28 2013-02-20 テルモ株式会社 ガイドワイヤ
US7744545B2 (en) 2006-12-28 2010-06-29 Terumo Kabushiki Kaisha Guide wire
JP2008161491A (ja) 2006-12-28 2008-07-17 Asahi Intecc Co Ltd 医療用ガイドワイヤ
US20080188298A1 (en) 2007-02-05 2008-08-07 Atlantic City Cion & Slot Service Company, Inc. Progressive gaming device and method of use
US8622931B2 (en) 2007-02-09 2014-01-07 Boston Scientific Scimed, Inc. Extruded guidewires and methods of making
JP4981471B2 (ja) 2007-02-09 2012-07-18 テルモ株式会社 ガイドワイヤ
WO2008100877A2 (en) 2007-02-15 2008-08-21 Vance Products Incorporated D/B/A, Cook Urological Incorporated Dual stiffness wire guide
JP2008245852A (ja) 2007-03-29 2008-10-16 Terumo Corp ガイドワイヤ
US20080262474A1 (en) 2007-04-20 2008-10-23 Boston Scientific Scimed, Inc. Medical device
US20080269641A1 (en) 2007-04-25 2008-10-30 Medtronic Vascular, Inc. Method of using a guidewire with stiffened distal section
JP5441336B2 (ja) 2007-05-11 2014-03-12 テルモ株式会社 ガイドワイヤ
US10220187B2 (en) 2010-06-16 2019-03-05 St. Jude Medical, Llc Ablation catheter having flexible tip with multiple flexible electrode segments
US8270834B2 (en) 2007-06-13 2012-09-18 West Jr Lamar E Frequency modulated burst mode optical system
WO2009003049A2 (en) 2007-06-25 2008-12-31 Micro Vention, Inc. Self-expanding prosthesis
US8409114B2 (en) 2007-08-02 2013-04-02 Boston Scientific Scimed, Inc. Composite elongate medical device including distal tubular member
US8105246B2 (en) 2007-08-03 2012-01-31 Boston Scientific Scimed, Inc. Elongate medical device having enhanced torque and methods thereof
US20090036832A1 (en) 2007-08-03 2009-02-05 Boston Scientific Scimed, Inc. Guidewires and methods for manufacturing guidewires
US8821477B2 (en) 2007-08-06 2014-09-02 Boston Scientific Scimed, Inc. Alternative micromachined structures
US9808595B2 (en) 2007-08-07 2017-11-07 Boston Scientific Scimed, Inc Microfabricated catheter with improved bonding structure
US20090118704A1 (en) 2007-11-02 2009-05-07 Boston Scientific Scimed, Inc. Interconnected ribbon coils, medical devices including an interconnected ribbon coil, and methods for manufacturing an interconnected ribbon coil
US20090118675A1 (en) 2007-11-02 2009-05-07 Boston Scientific Scimed, Inc. Elongate medical device with a shapeable tip
US8128579B2 (en) 2007-11-02 2012-03-06 Boston Scientific Scimed, Inc. Guidewires with improved fatigue life and methods of making the same
US7806837B2 (en) 2007-11-07 2010-10-05 William Cook Europe Aps Guide wire for catheter
US8460213B2 (en) 2008-01-03 2013-06-11 Boston Scientific Scimed, Inc. Cut tubular members for a medical device and methods for making and using the same
WO2009112048A1 (de) 2008-03-11 2009-09-17 Epflex Feinwerktechnik Gmbh Führungsdraht mit markierungsmunster
US8376961B2 (en) 2008-04-07 2013-02-19 Boston Scientific Scimed, Inc. Micromachined composite guidewire structure with anisotropic bending properties
US20090292225A1 (en) 2008-05-21 2009-11-26 Boston Scientific Scimed, Inc. Medical device including a braid for crossing an occlusion in a vessel
US20090318892A1 (en) 2008-06-20 2009-12-24 Maria Aboytes Removable Core Implant Delivery Catheter
CN201239164Y (zh) 2008-06-30 2009-05-20 扬州市瑞京科技发展有限公司 导丝输送装置
US8535243B2 (en) 2008-09-10 2013-09-17 Boston Scientific Scimed, Inc. Medical devices and tapered tubular members for use in medical devices
US20100063479A1 (en) 2008-09-10 2010-03-11 Boston Scientific Scimed, Inc. Small profile, tubular component design and method of manufacture
US20100069882A1 (en) 2008-09-18 2010-03-18 Boston Scientific Scimed, Inc. Medical device with preferential bending
US10363389B2 (en) 2009-04-03 2019-07-30 Scientia Vascular, Llc Micro-fabricated guidewire devices having varying diameters
US20220296850A1 (en) 2008-12-08 2022-09-22 Scientia Vascular, Inc. Micro-fabricated intravascular devices having varying diameters
US11406791B2 (en) 2009-04-03 2022-08-09 Scientia Vascular, Inc. Micro-fabricated guidewire devices having varying diameters
US8468919B2 (en) 2008-12-08 2013-06-25 Next Vascular, Llc Micro-cutting machine for forming cuts in products
US8795254B2 (en) 2008-12-10 2014-08-05 Boston Scientific Scimed, Inc. Medical devices with a slotted tubular member having improved stress distribution
KR20110102314A (ko) 2008-12-11 2011-09-16 카네카 코포레이션 의료용 튜브
US8444577B2 (en) 2009-01-05 2013-05-21 Cook Medical Technologies Llc Medical guide wire
US20100228150A1 (en) 2009-03-05 2010-09-09 Lake Region Medical, Inc. Neuro guidewire
US20100234816A1 (en) 2009-03-13 2010-09-16 Cook Incorporated Coated wire guide and method of making same
EP2409724B1 (en) 2009-03-19 2015-07-08 Japan Lifeline Co., Ltd. Medical guide wire
EP3284501B1 (en) 2009-04-03 2019-11-13 Scientia Vascular, LLC Guidewires for use in surgical procedures
US20100256603A1 (en) 2009-04-03 2010-10-07 Scientia Vascular, Llc Micro-fabricated Catheter Devices Formed Having Elastomeric Fill Compositions
US9616195B2 (en) 2009-04-03 2017-04-11 Scientia Vascular, Llc Micro-fabricated catheter devices having varying diameters
US9067332B2 (en) 2009-04-03 2015-06-30 Scientia Vascular, Llc Micro-fabricated catheter devices formed with hybrid materials
US20100256604A1 (en) 2009-04-03 2010-10-07 Scientia Vascular, Llc Micro-fabricated Catheter Devices Formed Having Elastomeric Compositions
US9950137B2 (en) 2009-04-03 2018-04-24 Scientia Vascular, Llc Micro-fabricated guidewire devices formed with hybrid materials
US9067333B2 (en) 2009-04-03 2015-06-30 Scientia Vascular, Llc Micro-fabricated guidewire devices having elastomeric fill compositions
KR101632457B1 (ko) 2009-04-14 2016-06-21 테루모 가부시키가이샤 의료용 가이드 와이어
JP4993632B2 (ja) 2009-06-16 2012-08-08 朝日インテック株式会社 医療用ガイドワイヤ
US8409169B1 (en) 2009-06-18 2013-04-02 Gerald Moss Catheter and method of making the same
JP5534727B2 (ja) 2009-07-15 2014-07-02 三桜工業株式会社 樹脂被覆金属管の金属管露出方法
US8118817B2 (en) 2009-07-21 2012-02-21 Cook Medical Technologies Llc Detachable embolization coil
US8376991B2 (en) * 2009-11-09 2013-02-19 St. Jude Medical, Atrial Fibrillation Division, Inc. Device for reducing axial shortening of catheter or sheath due to repeated deflection
US8137293B2 (en) 2009-11-17 2012-03-20 Boston Scientific Scimed, Inc. Guidewires including a porous nickel-titanium alloy
US20110160680A1 (en) 2009-12-29 2011-06-30 Cook Incorporated Wire guide with cannula
JP5146970B2 (ja) 2010-01-21 2013-02-20 朝日インテック株式会社 医療用ガイドワイヤ
US8454535B2 (en) 2010-01-29 2013-06-04 Cordis Corporation Highly flexible tubular device for medical use
US8357140B2 (en) 2010-01-29 2013-01-22 Cordis Corporation Highly flexible tubular device with high initial torque response for medical use
WO2012034135A1 (en) 2010-09-10 2012-03-15 Maria Aboytes Devices and methods for the treatment of vascular defects
JP2011206175A (ja) 2010-03-29 2011-10-20 Terumo Corp ガイドワイヤ
JP2013523282A (ja) 2010-03-31 2013-06-17 ボストン サイエンティフィック サイムド,インコーポレイテッド 曲げ剛性プロファイルを有するガイドワイヤ
US9795765B2 (en) 2010-04-09 2017-10-24 St. Jude Medical International Holding S.À R.L. Variable stiffness steering mechanism for catheters
US8870863B2 (en) 2010-04-26 2014-10-28 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses, systems, and methods for renal neuromodulation
US8500657B2 (en) 2010-08-23 2013-08-06 Abbott Cardiovascular Systems, Inc. Twisted ribbon wire guidewire coil
US8480598B2 (en) 2010-09-14 2013-07-09 Abbott Cardiovascular Systems Inc. Guide wire with soldered multilayer coil member
US8500658B2 (en) 2010-10-28 2013-08-06 Abbott Cardiovascular Systems Inc. Nickel-titanium core guide wire
US10010327B2 (en) 2010-12-16 2018-07-03 Lawrence Livermore National Security, Llc Expandable implant and implant system
JP5382953B2 (ja) 2011-01-28 2014-01-08 朝日インテック株式会社 ガイドワイヤ
US8795202B2 (en) 2011-02-04 2014-08-05 Boston Scientific Scimed, Inc. Guidewires and methods for making and using the same
US8622934B2 (en) 2011-04-25 2014-01-07 Medtronic Vascular, Inc. Guidewire with two flexible end portions and method of accessing a branch vessel therewith
JP6527329B2 (ja) 2011-05-03 2019-06-05 シファメド・ホールディングス・エルエルシー 操縦可能な送達シース
US9072874B2 (en) 2011-05-13 2015-07-07 Boston Scientific Scimed, Inc. Medical devices with a heat transfer region and a heat sink region and methods for manufacturing medical devices
JP5382881B2 (ja) 2011-06-15 2014-01-08 朝日インテック株式会社 ガイドワイヤ
JP2013013449A (ja) 2011-06-30 2013-01-24 Asahi Intecc Co Ltd ガイドワイヤ
US8676301B2 (en) 2011-07-14 2014-03-18 Med Works Limited Guide wire incorporating a handle
US9162046B2 (en) 2011-10-18 2015-10-20 Boston Scientific Scimed, Inc. Deflectable medical devices
US20130110000A1 (en) 2011-10-31 2013-05-02 Terumo Medical Corporation Dual Diameter Introducer Guide Wire
US20130123714A1 (en) 2011-11-15 2013-05-16 Boston Scientific Scimed, Inc. Vessel protection membrane
JP2013106854A (ja) 2011-11-22 2013-06-06 Asahi Intecc Co Ltd ガイドワイヤ
WO2013085749A1 (en) * 2011-12-05 2013-06-13 Stryker Corporation Reinforced elongate medical device and method of manufacture
CN104023782A (zh) 2011-12-28 2014-09-03 泰尔茂株式会社 导丝
EP2804547B1 (en) 2012-01-15 2018-04-04 Triticum Ltd. Device for removing occlusions in a biological vessel
US20130184703A1 (en) 2012-01-17 2013-07-18 Boston Scientific Scimed, Inc. Renal nerve modulation devices and methods for making and using the same
WO2013118649A1 (ja) 2012-02-07 2013-08-15 テルモ株式会社 ガイドワイヤ
US10029076B2 (en) 2012-02-28 2018-07-24 Covidien Lp Intravascular guidewire
US9216056B2 (en) * 2012-03-02 2015-12-22 Biosense Webster (Israel) Ltd. Catheter for treatment of atrial flutter having single action dual deflection mechanism
US9364640B2 (en) 2012-05-07 2016-06-14 St. Jude Medical Atrial Fibrillation Division, Inc. Medical device guidewire with helical cutout and coating
US9138566B2 (en) 2012-05-13 2015-09-22 Bendit Technologies Ltd. Steering tool
CN103764012B (zh) 2012-06-22 2016-03-09 奥林巴斯株式会社 弯曲管、医疗设备
US20140005558A1 (en) 2012-06-29 2014-01-02 Boston Scientific Scimed, Inc. Pressure sensing guidewire
US20140012281A1 (en) * 2012-07-09 2014-01-09 Boston Scientific Scimed, Inc. Expandable guide extension catheter
US9968762B2 (en) 2012-08-08 2018-05-15 Cook Medical Technologies Llc Wire guide with multiple tips
DE102012214785A1 (de) 2012-08-20 2014-02-20 Epflex Feinwerktechnik Gmbh Medizinischer Führungsdraht mit MR-Marker
US20140094787A1 (en) 2012-09-28 2014-04-03 Boston Scientific Scimed, Inc. Flexible renal nerve modulation device
US20140121642A1 (en) 2012-10-25 2014-05-01 Boston Scientific Scimed, Inc. Dual function medical devices
WO2014077881A1 (en) 2012-11-14 2014-05-22 Hollister Incorporated Urinary catheters having varying flexibility
US9433752B2 (en) 2012-11-14 2016-09-06 Biosense Webster (Israel) Ltd. Catheter with flat beam deflection in tip
WO2014081942A1 (en) 2012-11-21 2014-05-30 Concert Medical, Llc Preformed guidewire
US9474850B2 (en) 2012-12-11 2016-10-25 Biosense Webster (Israel) Ltd. Lasso catheter with guide wire
WO2014105578A1 (en) 2012-12-27 2014-07-03 Volcano Corporation Intravascular guidewire with hyper flexible distal end portion
US9848882B2 (en) 2013-03-08 2017-12-26 Scientia Vascular, Llc Micro-fabricated embolic devices
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
US20140279109A1 (en) * 2013-03-14 2014-09-18 Wiliam P. Vasquez Systems and methods for integrated, secure point-of-sale transactions having a peripheral authentication protocol
JP5814287B2 (ja) 2013-03-25 2015-11-17 株式会社フジクラ ガイドワイヤ
WO2014162393A1 (ja) 2013-04-01 2014-10-09 テルモ株式会社 ガイドワイヤ
CN105517618A (zh) 2013-07-03 2016-04-20 波士顿科学国际有限公司 导丝
EP3035990B1 (en) * 2013-08-23 2019-05-22 Boston Scientific Scimed, Inc. Catheters and catheter shafts
EP3653156B1 (en) 2013-10-25 2023-08-02 Intuitive Surgical Operations, Inc. Flexible instrument with grooved steerable tube
KR102360625B1 (ko) 2013-12-13 2022-02-09 인튜어티브 서지컬 오퍼레이션즈 인코포레이티드 삽통식 생검 바늘
US9937325B2 (en) * 2014-01-08 2018-04-10 Covidien Lp Catheter system
JP6154335B2 (ja) 2014-02-04 2017-06-28 株式会社メイワパックス 包装袋
US9987014B2 (en) 2014-02-06 2018-06-05 Boston Scientific Scimed, Inc. Occlusion device
JP6294211B2 (ja) 2014-02-24 2018-03-14 朝日インテック株式会社 ガイドワイヤ
DE202014100863U1 (de) 2014-02-26 2014-03-14 Cormedics Medizintechnik GmbH Führungsdraht für medizinische Vorrichtungen
WO2015141290A1 (ja) 2014-03-19 2015-09-24 テルモ株式会社 ガイドワイヤ
JP6251903B2 (ja) 2014-03-24 2017-12-27 グンゼ株式会社 医療用ガイドワイヤ
JP6109108B2 (ja) 2014-03-26 2017-04-05 大和ハウス工業株式会社 電力供給システム
JP5908192B2 (ja) 2014-04-08 2016-04-26 オリンパス株式会社 内視鏡
JP2017513643A (ja) 2014-04-28 2017-06-01 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 血管内デバイスのためのプレドープされた固体基質
US20150306355A1 (en) 2014-04-28 2015-10-29 Mark Edman Idstrom Guidewires with variable rigidity
EP3185756A2 (en) 2014-08-28 2017-07-05 Koninklijke Philips N.V. Intravascular devices, systems, and methods having an adhesive filled flexible element
CN206880937U (zh) * 2014-09-04 2018-01-16 雅培心血管系统有限公司 囊体导管
WO2016047499A1 (ja) 2014-09-26 2016-03-31 テルモ株式会社 ガイドワイヤ
JP2016077765A (ja) 2014-10-22 2016-05-16 朝日インテック株式会社 ガイドワイヤ
US20160135827A1 (en) 2014-11-13 2016-05-19 Cook Medical Technologies Llc Subintimal crossing wire guide
JP6746503B2 (ja) 2015-01-23 2020-08-26 テルモ株式会社 ガイドワイヤ
US11020017B2 (en) 2015-02-16 2021-06-01 Biosense Webster (Israel) Ltd. Angioplasty guidewire
EP3263170B1 (en) 2015-02-27 2021-05-19 Nipro Corporation Guide wire
WO2016152194A1 (ja) 2015-03-20 2016-09-29 テルモ株式会社 ガイドワイヤ
JP2016189998A (ja) 2015-03-31 2016-11-10 東レ・メディカル株式会社 カテーテル用ガイドワイヤ
US10263430B2 (en) 2015-08-14 2019-04-16 Solarcity Corporation Multi-phase inverter power control systems in an energy generation system
US10639456B2 (en) 2015-09-28 2020-05-05 Microvention, Inc. Guidewire with torque transmission element
CN105545375B (zh) 2015-12-14 2017-03-08 中国燃气涡轮研究院 双梁指尖密封装置
US20170203076A1 (en) 2016-01-15 2017-07-20 Boston Scientific Scimed, Inc. Slotted tube with planar steering
WO2017151292A1 (en) 2016-02-29 2017-09-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Transcatheter coronary sinus mitral valve annuloplasty procedure and coronary artery and myocardial protection device
JP2017169253A (ja) 2016-03-14 2017-09-21 日立マクセル株式会社 力率改善装置、及びそれを備えた蓄電装置
US10252024B2 (en) * 2016-04-05 2019-04-09 Stryker Corporation Medical devices and methods of manufacturing same
US11052228B2 (en) 2016-07-18 2021-07-06 Scientia Vascular, Llc Guidewire devices having shapeable tips and bypass cuts
US11207502B2 (en) 2016-07-18 2021-12-28 Scientia Vascular, Llc Guidewire devices having shapeable tips and bypass cuts
US11324495B2 (en) 2016-07-29 2022-05-10 Cephea Valve Technologies, Inc. Systems and methods for delivering an intravascular device to the mitral annulus
US10821268B2 (en) 2016-09-14 2020-11-03 Scientia Vascular, Llc Integrated coil vascular devices
US11452541B2 (en) 2016-12-22 2022-09-27 Scientia Vascular, Inc. Intravascular device having a selectively deflectable tip
JP6842933B2 (ja) 2017-01-20 2021-03-17 テルモ株式会社 ガイドワイヤおよびガイドワイヤの製造方法
KR102628519B1 (ko) 2017-05-26 2024-01-22 사이언시아 바스큘라, 아이엔씨. 비나선형 절개부 구조를 가지는 미세 제조 의료 장치
US20200094027A1 (en) 2017-05-26 2020-03-26 Scientia Vascular, Llc Core-wire joint with micro-fabricated medical devices
ES2923913T3 (es) 2017-07-06 2022-10-03 Edwards Lifesciences Corp Sistema de suministro de carril orientable
US11305095B2 (en) 2018-02-22 2022-04-19 Scientia Vascular, Llc Microfabricated catheter having an intermediate preferred bending section
US11285294B2 (en) 2018-08-17 2022-03-29 Cook Medical Technologies Llc Introducer with sheath having a withdrawal support wire
US20200222672A1 (en) 2019-01-15 2020-07-16 Scientia Vascular Guidewire with core centering mechanism
JP2022530067A (ja) 2019-04-24 2022-06-27 エコール・ポリテクニーク・フェデラル・ドゥ・ローザンヌ (ウ・ペ・エフ・エル) 強化されたトルク操縦可能なガイドワイヤ
US20200345975A1 (en) 2019-05-02 2020-11-05 Scientia Vascular, Llc Intravascular device with enhanced one-beam cut pattern
US20210228845A1 (en) 2020-01-23 2021-07-29 Scientia Vascular, Llc Guidewire having enlarged, micro-fabricated distal section
US20210346656A1 (en) 2020-01-23 2021-11-11 Scientia Vascular, Llc High torque guidewire device
US11759217B2 (en) 2020-04-07 2023-09-19 Neuravi Limited Catheter tubular support
US20220105312A1 (en) 2020-10-05 2022-04-07 Scientia Vascular, Llc Microfabricated catheter devices with high axial strength
US20220105318A1 (en) 2020-10-05 2022-04-07 Scientia Vascular, Llc Microfabricated core wire for an intravascular device
US20230082226A1 (en) 2021-09-03 2023-03-16 Scientia Vascular, Inc. Intravascular guidewire and microcatheter system
US20230071512A1 (en) 2021-09-03 2023-03-09 Scientia Vascular, Inc. Microcatheter device with non-linear bending stiffness

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5345945A (en) * 1990-08-29 1994-09-13 Baxter International Inc. Dual coil guidewire with radiopaque distal tip
US20040181174A2 (en) * 2002-07-25 2004-09-16 Precision Vascular Systems, Inc. Medical device for navigation through anatomy and method of making same
US20090177119A1 (en) * 2008-01-03 2009-07-09 Boston Scientific Scimed, Inc. Articulating intracorporeal medical device
US20100318066A1 (en) * 2009-06-16 2010-12-16 Asahi Intecc Co., Ltd. Medical guidewire
CN102049085A (zh) * 2009-10-27 2011-05-11 加藤富久 医疗引导线、制造医疗引导线的方法、与医疗引导线组合的微管和引导管的组件
CN102107041A (zh) * 2009-12-25 2011-06-29 朝日英达科株式会社 导线
US20140276109A1 (en) * 2013-03-15 2014-09-18 Boston Scientific Scimed, Inc. Pressure sensing guidewire
US20160199620A1 (en) * 2015-01-09 2016-07-14 Mivi Neuroscience Inc. Medical guidewires for tortuous vessels

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