CN1089232C - 将微水溶性药物转化为非晶态的方法 - Google Patents

将微水溶性药物转化为非晶态的方法 Download PDF

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Publication number
CN1089232C
CN1089232C CN96196203A CN96196203A CN1089232C CN 1089232 C CN1089232 C CN 1089232C CN 96196203 A CN96196203 A CN 96196203A CN 96196203 A CN96196203 A CN 96196203A CN 1089232 C CN1089232 C CN 1089232C
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salt
amorphous state
acid
slightly water
soluble medicine
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Expired - Fee Related
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CN96196203A
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Chinese (zh)
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CN1192677A (zh
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宫本操
织田寿久
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Nissan Chemical Corp
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Nissan Chemical Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Sludge (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN96196203A 1995-08-11 1996-08-08 将微水溶性药物转化为非晶态的方法 Expired - Fee Related CN1089232C (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP205936/95 1995-08-11
JP20593695 1995-08-11
JP31040195 1995-11-29
JP31040095 1995-11-29
JP310401/95 1995-11-29
JP310400/95 1995-11-29

Publications (2)

Publication Number Publication Date
CN1192677A CN1192677A (zh) 1998-09-09
CN1089232C true CN1089232C (zh) 2002-08-21

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ID=27328563

Family Applications (1)

Application Number Title Priority Date Filing Date
CN96196203A Expired - Fee Related CN1089232C (zh) 1995-08-11 1996-08-08 将微水溶性药物转化为非晶态的方法

Country Status (15)

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US (1) US6462093B1 (enrdf_load_stackoverflow)
EP (2) EP0852140B1 (enrdf_load_stackoverflow)
JP (1) JPWO9706781A1 (enrdf_load_stackoverflow)
KR (1) KR100498813B1 (enrdf_load_stackoverflow)
CN (1) CN1089232C (enrdf_load_stackoverflow)
AT (1) ATE255405T1 (enrdf_load_stackoverflow)
AU (1) AU702088B2 (enrdf_load_stackoverflow)
CA (1) CA2228907A1 (enrdf_load_stackoverflow)
CZ (1) CZ296072B6 (enrdf_load_stackoverflow)
DE (1) DE69630964T2 (enrdf_load_stackoverflow)
MX (1) MX9800717A (enrdf_load_stackoverflow)
NO (1) NO320486B1 (enrdf_load_stackoverflow)
NZ (1) NZ315089A (enrdf_load_stackoverflow)
TW (1) TW487582B (enrdf_load_stackoverflow)
WO (1) WO1997006781A1 (enrdf_load_stackoverflow)

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US6462093B1 (en) 2002-10-08
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CN1192677A (zh) 1998-09-09
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