CN108472438B - 至预填充的流体储存器的弯曲流体路径附加装置 - Google Patents

至预填充的流体储存器的弯曲流体路径附加装置 Download PDF

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CN108472438B
CN108472438B CN201680072280.4A CN201680072280A CN108472438B CN 108472438 B CN108472438 B CN 108472438B CN 201680072280 A CN201680072280 A CN 201680072280A CN 108472438 B CN108472438 B CN 108472438B
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attachment
fluid reservoir
fastener
coupling
adapter
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CN108472438A (zh
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O·卡比里
P·H·诺顿
R·希斯基安胡
R·布拉夫
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Western Medicine Services Israel Branch
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Western Medicine Services Israel Branch
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Priority claimed from US15/204,542 external-priority patent/US10576207B2/en
Priority claimed from US15/269,248 external-priority patent/US10086145B2/en
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Abstract

一种用于自注射器的附加装置包括适配器。该适配器包括至少一个联接器和弯曲的流体路径。联接器的尺寸和形状设计成将适配器联接到流体储存器，弯曲的流体路径在第一端构造为穿透组织并且在第二端联接至适配器。联接到流体储存器的附加装置形成一体式自注射器药筒单元，自注射器药筒单元被构造为无菌且注入有注射剂。该适配器被构造成能将多个具有不同尺寸和尖端类型的储存器的至少一个联接到自注射器。

Description

至预填充的流体储存器的弯曲流体路径附加装置
技术领域和背景技术
本发明在一些实施例中涉及一种自注射器(self-injector)，更具体地但非排他地涉及贴片式自注射器。
皮下(SC)注射是一种在皮肤下施用药物的方法，通常进入皮肤和肌肉之间的脂肪组织。目前生物制剂的皮下注射趋势使得使用者能够在家自注射，其使用诸如可重复使用的和一次性的笔、自动注射器和粘附在皮肤表面的贴剂注射器的皮下注射生物制品的自动注射器。
在许多情况下，重新配制的药物可能更浓，有时更粘稠并且所需的注射容积大于1mL。对于高粘度产品，在10秒内输送可导致注射疼痛，这可能导致使用者不遵循其治疗方案。对于使用者而言，在持续超过10秒或几分钟的注射期间，很难保持笔或其他直立式注射器静止并位于注射的正确角度。因此，用于自执行SC注射的贴剂自动注射器或自注射器正变得越来越普遍。
另外的背景技术包括专利号为6,843,782和专利号为5,858,001的美国专利。
发明内容
根据本发明一些实施例的一个方面，提供一种包括适配器的自注射器附加装置，适配器包括至少一个联接件和弯曲的流体路径，所述联接件的尺寸和形状设计成将适配器联接到流体储存器，所述的弯曲流体路径构造成在第一端穿透组织并在第二端联接到适配器，其中联接到流体储存器的附件形成一体式自注射器药筒单元，其构造为无菌且注入有注射剂(injectable)。
根据本发明的一些实施例，所述的附加装置包括针体保护帽。根据一些实施例，流体路径以90度角弯曲。根据一些实施例，附加装置还包括至少一个紧固件，其尺寸设计成并安装成用于将储存器的本体联接到自注射器。
根据本发明的一些实施例的一个方面，提供了一种用于自注射器的附加装置，该附加装置包括适配器，该适配器包括至少一个联接器，所述联接其的形状和尺寸设置成将所述适配器联接到流体储存器，弯曲的流体路径构造成在第一端部处穿透组织并且在第二端部处联接到所述适配器，并且其中当所述附加装置联接到所述流体储存器时，在储存器和弯曲的流体路径的第一端之间建立无菌流体连通。根据本发明的一些实施例，弯曲的流体路径包括在第二端处的联接件，其尺寸和形状设计成将弯曲的流体路径联接到适配器并且固定两者之间无菌的流体连通。根据本发明的一些实施例，附加装置还包括至少一个紧固件，其尺寸设计成并安装来用于将储存器的本体连接到自注射器。根据本发明的一些实施例，弯曲的流体路径包括中空针体。根据本发明的一些实施例，流体路径以90度角弯曲。
根据本发明的一些实施例，储存器是预填充药盒。根据本发明的一些实施例，储存器是注射筒。根据本发明的一些实施例，储存器是药水瓶。根据本发明的一些实施例，储存器的至少一部分由玻璃制成。根据本发明的一些实施例，储存器的至少一部分由塑料材料制成。根据本发明的一些实施例，附加装置可整体消毒。根据本发明的一些实施例，适配器联接器是鲁尔锁联接器。根据本发明的一些实施例，适配器联接器是药水瓶适配器。根据本发明的一些实施例，适配器联接器是滑动流体储液器联接器。根据本发明的一些实施例，适配器还包括联接件，其尺寸和形状被设计成将附加件联接到自注射器。
根据本发明的一些实施例的一个方面，提供了一种用于自注射器的附加装置，其包括至少一个适配器以及至少一个紧固件，该适配器包括至少一个弯曲的流体路径并且尺寸设计成并安装来用于无菌地将弯曲的流体路径联接到流体储存器的尖端，所述紧固件的尺寸设计成并安装至所述流体储存器的所述自注射器的本体，并且其中所述适配器和所述紧固件被配置为联接具有不同尺寸和尖端类型的多种储存器的至少一种的自注射器。
根据本发明的一些实施例，适配器与紧固件之间的距离是可调整的。根据本发明的一些实施例，紧固件的内径是可调整的。根据本发明的一些实施例，附加装置还包括尺寸和形状设计成沿沿紧固件的内周部安装的配件。根据本发明的一些实施例，配件减小了紧固件的内径。根据本发明的一些实施例，紧固件的至少一部分由塑料材料制成。根据本发明的一些实施例，流体储存器的至少一部分由玻璃制成。根据本发明的一些实施例，流体储存器的至少一部分由塑料材料制成。根据本发明的一些实施例，弯曲的流体路径包括中空针体。根据本发明的一些实施例，流体路径以90度角弯曲。
根据本发明的一些实施例，储存器是预填充药盒。根据本发明的一些实施例，储存器是流体储存器。根据本发明的一些实施例，储存器是药水瓶。根据本发明的一些实施例，附加装置可整体消毒。根据本发明的一些实施例，适配器联接器是鲁尔锁联接器。根据本发明的一些实施例，适配器联接器是药水瓶适配器。根据本发明的一些实施例，适配器联接器是滑动流体储液器联接器。根据本发明的一些实施例，适配器还包括联接件，其尺寸和形状被设计成将附加件联接到自注射器。
根据本发明的一些实施例的一个方面，提供了一种附加自注射器联接系统的附加装置，其包括自注射器、至少一个适配器和至少一个紧固件，所述自注射器包括具有多个附接点的支撑板，适配器包括至少一个弯曲的流体路径且尺寸设计成并安装来用于无菌地将弯曲的流体路径联接到流体储存器的至少一个尖端，紧固件的尺寸设计成并安装来用于联接到流体储存器的本体和联接到附接点中的至少一个。
根据本发明的一些实施例，适配器的尺寸设计成和安装来用于联接到至少一个附接点。根据本发明的一些实施例，附接点以距离适配器不同的距离分布在支撑板上。根据本发明的一些实施例，不同的距离对应于不同长度的流体储存器。根据本发明的一些实施例，紧固件的内径是可调节的。根据本发明的一些实施例，系统还包括尺寸和形状设计成沿沿紧固件的内周部安装的配件。根据本发明的一些实施例，配件减小了紧固件的内径。
根据本发明的一些实施例的一个方面，提供了一种自注射器套装，包括至少一个自注射器、多个适配器和多个紧固件，所述自注射器包括具有多个附接点的支撑板，适配器包括至少一个弯曲的流体路径且尺寸设计成并安装来用于无菌地将弯曲的流体路径联接到流体储存器的至少一个类型的至少一个尖端，紧固件尺寸设计成并安装以联接到至少一个直径的流体储存器的本体和联接到附接点中的至少一个。
根据本发明的一些实施例，根据权利要求45所述的套件，其中还包括至少一个配件，其尺寸和形状设计成沿多个紧固件的至少一个的内周部安装。根据本发明的一些实施例，配件减小了紧固件的内径。根据本发明的一些实施例，流体储存器是至少一个预填充药筒、注射筒和药水瓶的至少一个。根据本发明的一些实施例，流体储存器的至少一部分由玻璃制成。根据本发明的一些实施例，紧固件的至少一部分由塑料材料制成。根据本发明的一些实施例，至少一个适配器是无菌的。
根据本发明的一些实施例的一个方面，提供了一种组装用于自注射器的附加装置的方法，包括：选择空流体储存器，通过将至少一个自注射器药筒单元的尖端联接到包括至少一个弯曲流体路径的适配器从而形成自注射器药筒单元，所述适配器的尺寸设计成并安装来用于将弯曲流体路径流体地联接至流体储存器的至少一个尖端并在流体储存器与弯曲流体路径之间建立流体连通。
根据本发明的一些实施例，该方法进一步包括消毒药筒，用无菌注射剂注入流体储器，将活塞插入流体储器的非弯曲流体路径端并且无菌密封流体储器的端部。根据本发明的一些实施例，该方法还包括选择至少一个紧固件并且将紧固件联接到流体储存器的本体并且将紧固件联接到注射器的至少一个对应的附接点。
根据本发明的一些实施例的一个方面，提供了一种将用于自注射器的附加装置联接到流体储存器的方法，该方法包括：选择流体储存器，将流体储存器的至少一个尖端联接到适配器，适配器包括至少一个弯曲的流体路径并且尺寸设计成并安装成将弯曲的流体路径流体地联接到流体储存器的至少一个尖端并且在流体储存器和弯曲的流体路径之间建立无菌连通。
根据本发明的一些实施例，该方法还包括选择至少一个紧固件并且将紧固件联接到流体储存器的本体并且将紧固件联接到注射器的至少一个对应的附接点。
除非另外定义，否则本文使用的所有技术和/或科学术语具有与本发明所属领域的普通技术人员通常理解的相同的含义。尽管在本发明的实施例的实践或测试中可以使用与本文所述的方法和材料类似或等同的方法和材料，但是下面描述示例性的方法和/或材料。如果发生冲突，将控制包括定义在内的专利说明书。另外，这些材料、方法和实例仅是说明性的，并非意在限制。。
附图说明
这里仅通过举例的方式参照附图来描述本发明的一些实施例。现在具体参照附图详细说明，需强调所示出的细节是作为示例并且出于对本发明的实施例的说明性讨论的目的。就此而言，对于本领域技术人员而言，利用附图所作的描述对于可以如何实施本发明的实施例是显而易见的。
在附图中：
图1是贴片式自注射器的侧视简易视图；
图2A、2B是对模块化贴片式自注射器的可选示例性实施例的侧视简化图；
图3A-3P是注射器-流体储存器联接器的示例性实施例的截面图和透视图的简化图；
图4A-4H是模块化流体储存器-注射器联接系统的示例性实施例的平面图和透视图的简化图；
图5A、5B、5C、5D、5E、5F和5G是示出紧固件定位的部分截面侧视图简图；以及
图6是用于自注射的家用套件的平面图简图。
具体实施方式
本发明在一些实施例中涉及一种自注射器，更具体地但非排他地涉及贴片式自注射器。
本发明的一些实施例的一个方面涉及一种自注射器，该自注射器尺寸设计成并安装以将具有不同尺寸和尖端类型的流体储存器联接到注射器。在一些实施例中，自注射器包括至少一个针体支承部分和至少一个紧固件，紧固件可连接至注射器并且至少连接至流体储存器的筒体。在一些实施例中，针体支撑部分包括针体保护盖。在一些实施例中，自注射器和流体储存器被无菌提供。例如，储存器、针体支承部分和盖帽可以组装在一起并一起消毒。在一些实施例中，自注射器和流体储存器被非无菌提供。在一些实施例中，自注射器和流体储存器在注入注射剂之前被消毒。在一些实施例中，灭菌后的无菌流体储存器注入有注射剂，并提供无菌密封并盖上保护帽。在一些实施例中，针体支撑部分和紧固件之间的距离是可调整的。在一些实施例例，紧固件的内半径是可调整的。在一些实施例中，该注射器包括贴片型自注射器。在一些实施例中，注射器包括弯曲的针体。在一些实施例中，针体以90度角弯曲。在一些实施例中，注射器的至少一部分包括至少一个孔，其尺寸设计成并安装以容纳流体储存器尖端。在一些实施例中，针体的至少一部分穿过孔延伸。在一些实施例中，针体支撑部分固定在位。在一些实施例中，流体储存器包括注射筒。在一些实施例中，流体储存器包括药水瓶。在一些实施例中，流体储存器包括药筒。
在一些实施例中，自注射器的尺寸设计成并安装以容纳可再填充的流体储存器。在一些实施例中，自注射器的尺寸设计成并安装以容纳预填充的流体储存器。在一些实施例中，预填充流体储存器尖端被无菌密封。在一些实施例中，注射器包括将针连接至一个或多个流体储存器尖端类型的一个或多个适配器。在一些实施例中，适配器的尺寸设计成并安装来用于将针体联接到滑动式或推入式流体储存器尖端。在一些实施例中，适配器的尺寸设计成并安装来用于将针体连接到鲁尔锁(Luer-lock)流体储存器尖端。在一些实施例中，适配器的尺寸设计成并安装来用于将针体连接到导管型流体储存器尖端。在一些实施例中，适配器的尺寸设计成并安装来用于将针体连接到具有居中尖端的储存器。在一些实施例中，适配器的尺寸设计成并安装来用于将针体连接到具有离心尖端的储存器。
本发明的一些实施例的一个方面涉及自注射器，包括模块化流体储存器-注射器联接系统。在一些实施例中，模块化系统包括支撑板，该支撑板的尺寸设计成并安装来以适应不同类型和尺寸的流体储存器。在一些实施例中，注射器包括弯曲的针体。在一些实施例中，针体以90度角弯曲。在一些实施例中，支撑板包括一个或多个凹口，凹口构造成容纳将流体储存器固定到注射器的紧固件。在一些实施例中，一个或多个紧固件的至少一部分固定地联接到自注射器支撑板。在一些实施例中，一个或多个紧固件的至少一部分可释放地联接到自注射器支撑板。在一些实施例中，一个或多个紧固件包括至少一个孔口，该孔口尺寸设计成并安装来容纳流体储存器尖端。在一些实施例中，至少一个紧固件包括弯曲针体。在一些实施例中，至少一个紧固件包括至少一个孔口，其尺寸设计成并安装来容纳流体储存器尖端。在一些实施例中，针体的至少一部分穿过孔或孔口延伸。
在一些实施例中，至少一个紧固件包括锁舌和铰链。在一些实施例中，至少一个紧固件包括一个或多个锁舌。在一些实施例中，至少一个紧固件的尺寸被设计成并安装以紧固流体储存器的筒体。在一些实施例中，至少一个紧固件的尺寸被设计成并安装以紧固流体储存器的棘爪凸缘。在一些实施例中，至少一个紧固件包括至少一个配件，其尺寸设计成并安装来用于特定流体储存器筒体直径。在一些实施例中，至少一个紧固件配备有至少部分有弹性的垫。在一些实施例中，当锁定在注射器中的位置时，流体储存器的至少一部分被推靠在弹性垫上。在一些实施例中，弹性垫阻止流体储存器尖端-针体联接处的泄漏。在一些实施例中，弹性垫包括用于针体尖端的孔。
本发明的一些实施例的一个方面涉及一种自注射器，其包括弯曲的针体并具有鲁尔锁(Luer-lock)联接器，其尺寸设计成并安装以接纳具有公鲁尔锁型尖端的流体储存器。在一些实施例中，鲁尔锁联接器包括圆柱体，圆柱体的一端连接到注射器并且包括配置成入拧入公鲁尔锁流体储存器尖端中的突片边缘。在一些实施例中，弯曲针体的至少一部分设置在圆柱体的内腔中。在一些实施例中，针体的至少一部分附接到圆柱体的内壁。在一些实施例中，针体的一部分和内壁之间的圆柱腔的至少一部分包括密封件。在一些实施例中，弯曲针体的至少一端延伸超过圆柱形突片边缘。在一些实施例中，延伸超过圆柱形突片边缘的弯曲针体的端部包括保护套。在一些实施例中，保护套保持针体端部的无菌性。在一些实施例中，保护套保持圆柱腔内针体的部分无菌直至并且包括延伸超过突出边缘的针体的端部。在一些实施例中，在联接时，公鲁尔锁的边缘将保护套推靠在针体的尖端上。在一些实施例中，针体的尖端通过公鲁尔锁定边缘破坏推向针尖的保护套。
本发明的一些实施例的一个方面涉及一种自注射器，其尺寸涉及成并安装以无菌地容纳不同类型和尺寸的流体储存器。在一些实施例中，自注射器包括联接器，该联接器在连接到含有注射剂的流体储存器期间和之后保持注射剂通路的无菌性。在一些实施例中，注射器联接件包括针体一端至少部分地被至少一个保护性护套隔开。在一些实施例中，在联接期间，联接的流体储存器的尖端推动至少一个护套抵靠针体端部破坏护套。在一些实施例中，联接的流体储存器的尖端包括在尖端开口上方的密封膜。在一些实施例中，在连接期间，注射器针体被推靠在膜上并穿透流体储存器尖端。
本发明的一些实施例的一个方面涉及一种自注射器套件，其包括支撑板和多个紧固件和配件，其尺寸设计成并安装以附接到支撑板。在一些实施例中，所述多个紧固件和配件的尺寸设计成并安装以无菌地容纳不同类型和尺寸的流体储存器。在一些实施例中，多个紧固件包括快速附接型联接件。在一些实施例中，所述多个紧固件包括至少一个一键式联接器。在一些实施例中，可以联接各种紧固件在各种期望的位置的支撑位置。在一些实施例中，至少一个紧固件包括弯曲针体。在一些实施例中，一个或多个紧固件构造成容纳至少一个配件。在一些实施例中，一个或多个紧固件和/或配件包括不同内径的一个或多个孔以配合至少一个流体储存器的至少一个筒体和/或棘爪凸缘。
本发明的一些实施例的一个方面涉及一种将不同类型和尺寸的流体储存器装载到自注射器的方法。在一些实施例中，该方法包括一个或多个紧固件，其尺寸设计成并安装来用于所选流体储存器的筒体和棘爪凸缘。在一些实施例中，该方法可选地包括选择至少一个配件，其尺寸设计成并安装来用于所选的流体储存器的筒体和棘爪凸缘。在一些实施例中，该方法还包括可选地将一个或多个配件滑动或联接到流体储存器的筒体或棘爪凸缘。在一些实施例中，该方法还包括将一个或多个紧固件滑动或联接到流体储存器的筒体或棘爪凸缘。在一些实施例中，该方法还包括将流体储存器的尖端插入到注射器的针体部分的孔口中。在一些实施例中，该方法还包括可选地将流体储存器的尖端插入到针头支撑紧固件的孔中。在一些实施例中，该方法还包括将紧固件连接到支撑板。在一些实施例中，该方法还包括将流体储存器连接到注射器流体贮存器柱塞驱动系统。
介绍
现在参考图1，其为贴片型自注射器的侧视图简图，如在申请号为62/284,806的美国临时专利申请中所描述的，并且因此整体引入。自注射器100包括弯曲的针体102，例如，以90度的角度弯曲连接至药筒104。药筒104可以预注入注射剂。药盒104可以安装在支撑板106上并且包括由电动机驱动齿轮110驱动的柱塞108。在注射程序之后，药筒104可被丢弃并由新的预填充药筒代替。
注射器动力总成和柱塞驱动系统在上面引用的申请号为62/284,806的美国临时专利申请中有详细说明，因此在此不再赘述。
模块自注射器流体储存器连接系统的可选组件
现在参考图2A、2B(统称为图2)，是对模块化贴片型自注射器的可选示例性实施例的侧视简化图。如图2所示，自注射器200尺寸设置为并安装为可以适应各种类型和尺寸的流体储存器。如在图1的示例中，在一些实施例中，自注射器200包括弯曲的针体202，例如以90度角弯曲。如在本公开其他部分更详细解释的，在一些实施例中，自注射器200包括支撑板204和至少一个针体202支承部分206。在一些实施例中，针体支撑部分206包括至少一个孔208，该孔的尺寸设计成并安装成容纳流体储存器250/255的尖端252。在一些实施例中，孔208包括通向针体202的弯曲部分212的孔口210。在一些实施例中，针体202的至少一部分紧密地穿过孔口210延伸并延伸入孔208。在一些实施例中，针体支撑部分206被固定在支撑板204上。
在一些实施例中，如图2A所示，孔208偏心地设置在针体支撑部分206内以容纳偏心尖端流体储存器。在一些实施例中，如图2B所示，孔208居中设置在针体支撑部分206内以容纳规则(中心的)尖端流体储存器。
注射器流体储存器连接器的可选示例
常用的流体储存器尖端包括滑动式或推动式尖端和鲁尔锁式尖端。塑料流体储存器包含两种类型的塑料尖端，而玻璃流体储存器尖端通常由金属制成。一些玻璃流体储存器包括玻璃滑动式尖端。常用的流体储液器-针体连接实践试图保持无菌的可注射通道，但是这有时可能是有挑战性的。通常的做法是将流体储存器和针体都分别储存在无菌袋中，以限制从袋中取出的时刻到注射时刻的暴露于外界的时间。当涉及到自注射器，特别是贴片式自注射器时，这种做法是不实际的。
滑动式/推入式
现在参考图3A-3P(统称为图3)，其是注射器-流体储存器联接器的示例性实施例的截面图和透视图的简化图。图3A-3L的示例性实施例描绘了将针体202连接到一个或多个不同流体储存器尖端类型的一个或多个适配器。例如，图3A示出了针体支撑部分206，其包括适配器302，该适配器302的尺寸被设计成并安装成将针体202连接到滑动式或推入式流体储存器尖端352。设置在中央的孔308在一侧朝面向流体储存器的开口306开设以接收流体储存器尖端并且在相对侧上在孔口310处结束，孔口310设计成密封地容纳针体202的至少一部分。可选地，在一些实施例中，孔308包括锥形几何形状。在一些实施例中，孔308包括圆柱几何形状。可选地并且也如图3C所示，在一些实施例中，针体支撑部分206还可包括弹性配件312，弹性配件312粘附或通过任何其他合适的方法覆盖在开口306上。在一些实施例中，配件312可以包括孔口314，该孔口的尺寸被设计成容纳相应尺寸的滑动式流体储存器尖端。在一些实施例中，当将流体储存器350的至少一部分在被锁定到注射器中的适当位置同时抵靠弹性配件时，弹性配件312阻止流体储存器针尖-针体连接泄漏的可能性。
在一些实施例中，如图3B所示，配件312可由弹性类型的合适材料(例如，硅酮)制成，以在流体储存器筒体352被抵靠在针体支撑部分206上时充当密封件并密封件开口306。
如图3A和3B所示，在一些实施例中，当流体储存器350连接到自注射器时，针体316的端部可至少部分地延伸到孔308中并进入流体储存器尖端354的内腔。如图3D和3E所示，流体储存器350的尖端可被密封以便消毒。例如，流体储存器尖端356(图3D)的开口可以由膜358密封，或者可选地，流体储存器尖端360(图3E)可以被保护性护套362覆盖。在一些实施例中，联接到流体储存器350时，延伸至孔308中的针体202的端部316被配置为破坏用于保护流体储存器350内部的注射剂无菌性的大部分类型的流体储存器尖端密封件。在一些实施例中，并且在图3F中示出，配件312孔径314可以由膜状密封件320密封。在一些实施例中，当自注射器200连接到流体储存器350时，流体储存器350的尖端356/360可破坏膜状密封件320。
鲁尔锁式(Luer-lock type)
现参照3G-3I，其示出了自注射器200，自注射器200包括弯曲针体202和鲁尔锁联接件316，其尺寸设计成并安装来以容纳具有公鲁尔锁式尖端362的流体储存器350。在一些实施例中，鲁尔锁联接件316包括圆柱体，圆柱体在一端密封地连接到针体202和注射器200，并且圆柱体包括在相对端的突片边缘322，突片边缘322朝向孔308的开口306开口。在一些实施例中，突片边缘322被配置成拧入鲁尔锁流体储存器尖端362上的套筒364。图3I示出处于完全配合构造的鲁尔锁联接件316和鲁尔锁式流体储存器350尖端362。
图3J-3L描绘的实施例示出了类似于本公开其他部分所描述的鲁尔锁联接器系统。可选地，在一些实施例中并且如图3J所示，延伸超出鲁尔锁联接件316的突片边缘322的弯曲针体202的端部324包括保护性护套318，保护性护套318构造成保持针体端部324无菌。在一些实施例中，保护性护套318由易弯曲的膜状材料制成，例如橡胶、聚氨酯或任何其他合适的材料。在一些实施例中，当如图3K所示配合时，鲁尔锁流体储存器350尖端362的边缘366推动保护套318抵靠针体端部324。在一些实施例中并且如图3K所示，针体端部324在进入流体储存器鲁尔锁尖端362的内腔368时破坏保护性护套318。图3L示出处于完全配合构造的鲁尔锁定联接件316和鲁尔锁式流体储存器350尖端362。另外并且可选地，在一些实施例中，流体储存器公鲁尔锁尖端316包括密封件，其类似于流体储存器尖端356的密封件358。
在一些实施例中，如图3M和3N所示，自注射器可以包括弯曲的针体适配器370，其包括流体储存器联接件和第二联接件375，流体储存器联接件类似于本公开中其他部分所述的示例，第二联接件375位于适配器370的第二端部。在图3M和3N示例中描述的第二联接器375包括鲁尔锁尖端。盖377保护第二联接器375免受外界影响并维持针体适配器370的无菌性。在一些实施例中，适配器370提供将标准针体379连接到自注射器200的自由度。在图3N所示的示例性实施例中，保护帽377已被移除并且鲁尔锁尖端针体379联接到针体适配器370和流体储存器350上。
如图3O和3P所示，弯曲针体适配器376的示例性实施例包括药水瓶适配器357，例如申请号为7，326，194的美国专利中描述的蒙达蒙普医疗项目公司(Medimop MedicalProjects Ltd.)的药水瓶适配器。在一些实施例中，弯曲的针体适配器376包括无菌盖359。在一些实施例中，弯曲针体适配器376包括针体帽377。可选地和替代地并且如图3P所示，弯曲的针体适配器376可以连接到空的药水瓶378上以形成单独的非无菌的自注射器药盒单元365。在一些实施例中，药盒单元365然后可以被消毒并且注入有注射剂。
紧固件和配件的可选示例
本发明的一些实施例的一个方面涉及自注射器，其包括模块化流体储存器-注射器联接系统。自注射器和专门的贴片自注射器设计成在注射过程中避免注射针在组织中的移动，从而最大程度地减少与注射相关的疼痛。这通过将注射针和/或流体储存器药盒固定连接到自注射器壳体的各种联接方法来实现。
现在参考图4A-4H(统称为图4)，其是模块化流体储存器-注射器联接系统的示例性实施例的平面图和透视图的简化图。在图4所示的示例中，自注射器200包括一个或多个紧固件402，其尺寸设计成并安装来容纳流体储存器450的至少一个筒体452或棘爪凸缘454。在一些实施例中，如图4A和4B所示，注射器200包括一个或多个紧固件，其被配置为将变化类型和尺寸的流体储存器连接到自注射器200。如图4A所示，在一些实施例中，紧固件404包括环形几何形状，其尺寸设计成和安装以滑动到相应直径的流体储存器筒体上。在一些实施例中，紧固件404还包括从紧固件404的周部延伸的至少一个突起406。在图4A所示的示例性实施例中，突起406从紧固件404的环部切向延伸，然而突起406可以径向或以任何其他合适的几何构造延伸。在一些实施例中，突起406至少平行于支撑板410的表面408取向。在图4A所示的示例性实施例中，至少一个突起406通过至少一个助留构件固定地联接到支撑板410。在图4A所示的示例中，附接构件包括保持悬臂412。在一些实施例中，保持悬臂412是弹性的和/或包括联接至支撑板410的至少一个弹性联接件。然而，附接构件可以包括任何类型的合适的附接机构。在一些实施例中，保持悬臂412被配置为将紧固件404突起406可释放地联接到支撑板。图4B和图4C示出了示例的实施例，其中紧固件414包括倒U形几何形状。在一些实施例中，支撑板410具有构造成容纳紧固件414的腿部418的多个凹口416。在一些实施例中，支撑板410的凹口416包括保持悬臂420，保持悬臂420构造成通过安装入腿部418中的一个或多个相应的凹槽422中而将紧固件414可释放地联接到支撑板。可选地，多个凹槽422通过调节紧固件414的一个或多个腿部418插入支撑板410的深度来支持紧固件414的内部半径的调节。因此，多个凹槽422使紧固件414构造成具有安装各种流体储存器的尺寸。
如图4D所示，在一些实施例中，支撑板410包括多个附接点412/416，多个附接点412/416分布成允许紧固件402/414/424以距离针体部分206不同的距离联接到支撑板410，以容纳不同长度的流体储存器。在一些实施例中，附接点412/416可选地包括图4A中所示类型的悬臂420。在一些实施例中，附接点412/416可选地包括凹口416和保持悬臂420，其被构造成将图4B和图4C中所示类型的紧固件可释放地联接。在一些实施例中，附接点412/416可选地包括滑动铰链和保持臂，其处于图4E和4F所示的构型中。另外并且可选地，附接点412/416可以包括除了本文描述的示例性实施例之外的任何类似的合适附接机构。
图4E和4F示出了示例的实施例，其中紧固件424包括铰接的倒U形几何形状。在图4E和4F所示例子中，一腿部426包括滑动铰链428，滑动铰链428构造成当打开时形成大间隙以释放或容纳流体储存器筒体452。在图4E所示的闭合构造中，紧固件424的非铰接腿部426通过保持悬臂420锁定在位。
在一些实施例中，紧固件402/414/424中的至少一个包括相同的尺寸以安装到相同的支撑板410上。在一些实施例中，如图4G和4H所示，紧固件402/414/424装配有一个或多个不同直径的环形几何形状配件430(图4H)，其尺寸设计成和配合特定流体储存筒体的相应直径。在一些实施例中，配件430被构造成滑动到流体储存器450的筒体452上，并且当紧固件(例如弹簧紧固件414/424)处于闭合构型是提供充分的摩擦以防止流体储存器筒体452相对于支撑板410的轴向滑动和移动。
图4G和4H示出了4B和4C所示类型的紧固件，但是配件430可以装配在本文所述的任何一个紧固件中或任何其它类似类型的紧固件中。
适配器-流体储液器联接件和紧固件定位的可选示例
为了确保流体储存器与自注射器的固定连接，除了将流体储存器固定到诸如支撑板410的表面之外，需要调节诸如紧固件420/414/424的紧固件到流体储存器筒体的长度。在大多数情况下，这可以通过如本公开的其他部分所述的沿着流体储存器筒体滑动紧固件和/或将紧固件连接到流体储存器的棘爪凸缘来实现。在本公开内容的其他部分描述的模块化支撑板410的结构允许当被安装到流体储存器筒体或棘爪凸缘时将紧固件定位在几乎任何期望的位置处。现在参考图5A-5G，其为将流体储存器联接到自注射器的紧固件定位的部分截面侧视图简图。
在图5A所示的示例性实施例中，空的流体储存器590联接至针体支撑部分534以形成单个整体式自注射器药筒单元535。在一些实施例中，药筒单元535是无菌的。在一些实施例中，药筒单元535是非无菌的。在一些实施例中，药筒单元535被消毒，以无菌方式注入注射剂并无菌、密封提供并准备使用。如图5B所示的示例性实施例所示，无菌预注入的药筒单元535通过一个或多个紧固件402(图4A)联接到支撑板410。在一些实施例中，药筒单元535包括柱塞570并且在无菌注入之后用密封件595密封。在一些实施例中，药筒单元535未消毒地输送以在包膜(例如塑料泡罩539)内消毒和填充。如图5C所示，包括滑动式尖端的流体储存器550(例如20cc流体储存器)安装到自注射器500上。在图5C所示的示例性实施例中，尖端502被示出为以本公开中其他部分描述的方式(不在赘述)插入到针体支撑部分506中。在图5C所示的示例性实施例中，针体支撑部分506包括类似于紧固件504联接器的联接器，并且可逆地联接到支撑板410。在一些实施例中，本公开中其他部分描述(不再赘述)的形式和功能的一个或多个紧固件504沿筒体452定位，其中至少一个紧靠联接流体储存器450的筒体452的棘爪凸缘454以支撑板410。在一些实施例中，当闭合时，紧固件504提供抵靠筒体452的足够摩擦，以防止筒体452相对于支撑板410的轴向滑动和移动。可替换地和可选地，在一些实施例中，本公开中其他部分描述类型的配件可以装配在紧固件504内并且提供抵靠筒体452的足够摩擦，以防止筒体452相对于支撑板410的轴向滑动和移动。
替代地并且可选地并且如图5D所示，在一些实施例中，紧固件506包括沿着内壁510的径向狭槽508，其尺寸被设计成和安装成容纳相应尺寸的流体储存棘爪凸缘454。替代地并且可选地并且如图5E所示，在一些实施例中，紧固件504类型的紧固件包括安装在紧固件504内部的配件512，其包括沿配件512的内壁的径向狭槽514，其尺寸被设计成并安装成容纳相应尺寸的流体储存器棘爪凸缘454。在一些实施例中，配件512提供抵靠棘爪凸缘454的足够摩擦，以防止筒体452相对于支撑板410的轴向滑动和移动。在图5D中，流体储存器柱塞已经被构造成由自注射器500柱塞驱动系统(未示出)驱动的柱塞570替代。
替换地并且可选地，图5F中示出了模块化流体储存器-注射器联接系统，其将小尺寸流体储存器555(例如5cc流体储存器)联接到自注射器500。流体储存器555的滑动式尖端被示出为以本公开中其他部分所述的方式(不再赘述)插入到针体支撑部分506中。在一些实施例中，本公开中其他部分描述(不再赘述)的形式和功能的一个或多个紧固件504沿筒体552定位，其中至少一个紧靠联接流体储存器555的筒体552的棘爪凸缘554以支撑板410。在一些实施例中，当闭合时，紧固件504提供抵靠筒体552的足够摩擦，以防止筒体552相对于支撑板410的轴向滑动和移动。可替换地和可选地，在一些实施例中，本公开中其他部分描述类型的配件430可以装配在紧固件504内并且提供抵靠筒体552的足够摩擦，以防止筒体552相对于支撑板410的轴向滑动和移动。
在图5F所示的实施例中，安装在紧固件504内部的配件512的尺寸设计成并安装成适应对应尺寸的流体储存棘爪凸缘554。如图5G所示，针体支撑部分506包括联接件537以支撑板，联接件类似于紧固件504的联接件或本公开中其他部分所述的任何类型的紧固件联接件，并且可逆地联接到支撑板410。如图5G所示，在一些实施例中，无棘爪凸缘的流体储存器590密封地附接到针体支撑部分506。在图5G中描述的示例性实施例中，流体储存器590是预填充的药水瓶，其附接到针体支撑部分506并且装配有紧固件402(图4C)以安装到支撑板410上，如本公开其他部分中所解释的。在一些实施例中，针体支撑部分506包括针体202和保护帽377。在一些实施例中，流体储存器590用密封件595无菌密封。在一些实施例中，附接到针体支撑部分506的预填充流体储存器590被输送到诸如塑料泡罩539的包膜中。现在参考图6，其是用于自注射的家用套件的平面图简图。如图6所示，在一些实施例中，套件600包括图6中由模块化支撑板410、多个紧固件602和包括各种内径的各种配件604表示的自注射器。
另外并且可选地，在一些实施例中，套件600可以包括标记，其帮助用户为相应的选定流体储存器选择正确的紧固件或配件。例如，在图6所示的示例性实施例中，对于选定的50cc流体储存器，使用者可以仅选择紧固件以将流体储存器充分地联接到自注射器。对于较小尺寸的流体储存器(例如10cc流体储存器)，使用者可以选择将标记为“10cc”的紧固件和的配件插入紧固器中。在一些实施例中，套件600包括用于适配紧固件和配件的尺寸和类型的清楚标记的指示符(例如，“5cc”、“10cc”、“20cc”、“50cc”、“尖端”，“凸缘”等)。
在一些实施例中，使用者可使用套件600通过将自注射器从套件移除并打开盖以暴露支撑板410来将流体储存器联接至自注射器。在一些实施例中，该方法还包括将针体部分506联接到流体储存器。在一些实施例中，针体支撑部分506包括针体保护帽377。在一些实施例中，该方法还包括选择一个或多个紧固件602并将一个或多个紧固件滑动到流体储存器的筒体452/552上。可替换地并且可选地，该方法包括将一个或多个紧固件602联接到支撑板410。可选地，该方法包括在滑动到流体储存器的筒体452/552之前将一个或多个配件604插入一个或多个紧固件602中。另外并且可选地，该方法包括选择棘爪凸缘紧固件606并且将流体储存器凸缘联接到支撑板410。可选地，该方法包括在将流体储存器凸缘联接到支撑板410之前将一个或多个棘爪凸缘配件608插入到一个或多个紧固件602中。可选地，该方法包括选择至少一个附接点412/416并将紧固件604/606附接到所选附接点412/416。
术语“包括”，“包括有”，“包含”，“包含于”，“具有”及其结合的意思是“包括但不限于”。
术语“由...组成”表示“包括并限于”。
术语“基本上由...组成”是指组合物、方法或结构可以包括附加的成分、步骤和/或部分，但仅指附加成分、步骤和/或部分不会实质上改变要求保护的组合物、方法或结构的基本特征和新颖特征。
如本文所用，除非上下文另外明确指出，否则单数形式“一”，“一个”和“该”包括复数指代。
在整个申请中，本发明的实施例可以参考范围形式来呈现。应该理解的是，范围形式的描述仅仅是为了方便和简洁，并且不应该被解释为对本发明范围的不灵活的限制。因此，范围的描述应被视为具体公开了所有可能的子范围以及该范围内的单个数值。例如，诸如“1至6”范围的描述应该被认为具有特定公开的子范围，例如“从1到3”、“从1到4”、“从1到5”、“从2到4”、“从2至6”，“从3至6”等。以及该范围内的个别数字，例如1、2、3、4、5和6。适用于所有范围的宽度。
本文中无论何时指示数字范围(例如“10-15”、“10至15”或由这些另一范围指示链接的任何一对数字)，其旨在包括指示范围限制内的任何数字(分数或整数)，包括范围限制，除非上下文另有明确规定。在本文中，第一指示数字和第二指示数字之间的“范围/排列/范围于”和从第一指示数“到”，“达到”，“直到”或“通过”(或另一个这样的范围指示术语)第二指示数字可互换地使用，并且旨在包括第一指示数字和第二指示数字以及其间的所有分数和整数。
除非另外指明，否则本文使用的数字和基于其的任何数字范围是本领域技术人员所理解的合理测量精确度和舍入误差内的近似值。
应该认识到，为了清楚起见，在单独实施例的上下文中描述的本发明的某些特征也可以在单个实施例中组合提供。相反地，为了简洁起见，在单个实施例的上下文中描述的本发明的各种特征也可以单独地或以任何合适的子组合或者在本发明的任何其他描述的实施例中合适地提供。除非实施例在没有那些元件的情况下不起作用，否则在各种实施例的上下文中描述的某些特征不被认为是那些实施例的基本特征。
虽然已经结合其具体实施例描述了本发明，但对于本领域技术人员而言，许多替代、修改和变化将是显而易见的。因此，旨在涵盖落入所附权利要求的精神和广泛范围内的所有这些替代、修改和变化。
本说明书中提及的所有出版物、专利和专利申请在此通过引用整体并入本说明书，其程度如同每个单独的出版物、专利或专利申请被具体和单独地指出通过引用并入本文。另外，本申请中任何参考文献的引用或标识不应被解释为承认这种参考文献可作为本发明的现有技术。在使用章节标题的范围内，不应将其解释为限制。

Claims (33)

1.一种用于自注射器的附加装置，其特征在于，包括：
适配器，所述适配器包括在所述适配器的第一端部的第一联接器，所述第一联接器的尺寸和形状设计成将所述适配器联接到流体储存器、在所述适配器的第二端部的第二联接器、从所述第一联接器延伸的第一主体部分，所述第一主体部分沿着第一轴线伸长、从所述第二联接器延伸的第二主体部分，所述第二主体部分沿着与所述第一轴线成角度地偏移的第二轴线伸长、以及连接所述第一主体部分和第二主体部分的肘部部分；
刚性且弯曲的流体路径，所述刚性且弯曲的流体路径具有第一端和第二端，所述第一端构造成穿透组织，所述第二端连接至所述适配器；以及
针体保护帽，所述针体保护帽覆盖所述流体路径的所述第一端；以及
保护性护套，所述保护性护套覆盖所述流体路径的所述第二端；
其中所述附加装置联接到所述流体储存器，使得所述流体路径的第二端与所述流体储存器流体连通，以及
其中联接到所述流体储存器的附加装置形成一体式自注射器药筒单元，所述的自注射器药筒单元构造为无菌且注入有注射剂。
2.根据权利要求1所述的附加装置，其特征在于，所述的流体路径以90度角度弯曲。
3.根据权利要求1所述的附加装置，其特征在于，所述的附加装置还包括至少一个紧固件，所述紧固件尺寸设计成并安装来用于将所述流体储存器的本体联接到自注射器。
4.根据权利要求3所述的附加装置，其特征在于，所述至少一个紧固件的内径是可调整的，
其中所述适配器和所述紧固件被配置为联接具有不同尺寸和尖端类型的多种储存器的至少一种的所述自注射器。
5.根据权利要求4所述的附加装置，其特征在于，所述适配器和所述紧固件之间的距离是可调整的。
6.根据权利要求5所述的附加装置，其特征在于，所述多种储存器包括流体储存器。
7.根据权利要求3所述的附加装置，其特征在于，所述附加装置还包括尺寸和形状设计成沿着所述至少一个紧固件的内周安装的配件。
8.根据权利要求7所述的附加装置，其特征在于，所述配件减小所述至少一个紧固件的内径。
9.根据权利要求3所述的附加装置，其特征在于，所述至少一个紧固件的至少一部分由塑料材料制成。
10.根据权利要求1所述的附加装置，其特征在于，所述的弯曲的流体路径包括空心的针体。
11.根据权利要求1所述的附加装置，其特征在于，所述的储存器是预填充药筒。
12.根据权利要求1所述的附加装置，其特征在于，所述的储存器是注射筒。
13.根据权利要求1所述的附加装置，其特征在于，所述的储存器是药水瓶。
14.根据权利要求1所述的附加装置，其特征在于，所述的储存器的至少一部分由玻璃制成。
15.根据权利要求1所述的附加装置，其特征在于，所述的储存器的至少一部分由塑料材料制成。
16.根据权利要求1所述的附加装置，其特征在于，所述的储存器是可整体消毒的。
17.根据权利要求1所述的附加装置，其特征在于，所述的适配器的联接器是药水瓶适配器。
18.根据权利要求1所述的附加装置，其特征在于，所述的适配器还包括联接件，所述的联接件的尺寸和形状设计成将所述附加装置联接到自注射器。
19.根据权利要求1所述的附加装置，其特征在于，所述第二联接器的尺寸和形状被设计成将所述弯曲流体路径联接到所述适配器并确保其间的无菌流体连通。
20.根据权利要求1所述的附加装置，其特征在于，所述第一联接器是鲁尔锁联接器。
21.根据权利要求1所述的附加装置，其特征在于，所述第一联接器和所述第二联接器中的至少一个联接器是滑动式流体储存器联接器。
22.根据权利要求1所述的附加装置，其特征在于，所述第二联接器是鲁尔锁联接器。
23.一种自注射器联接系统，其特征在于，包括：
自注射器，所述自注射器包括带有多个附接点的支撑板；
根据权利要求1-22任一项所述的附加装置；
至少一个紧固件，其尺寸设计成并安装以联接到所述流体储存器的本体和联接到所述附接点的至少一个；和
保持悬臂，所述保持悬臂被配置为将所述至少一个紧固件可释放地联接到所述支撑板。
24.根据权利要求23所述的系统，其特征在于，所述适配器的尺寸设计成并安装来用于联接到所述附接点中的至少一个。
25.根据权利要求24所述的系统，其特征在于，所述附接点以距离所述适配器不同的距离分布在所述支撑板上。
26.根据权利要求25所述的系统，其特征在于，所述不同的距离对应于不同长度的流体储存器。
27.一种自注射器套件，其特征在于，
至少一个自注射器，所述至少一个自注射器包括带有多个附接点的支撑板；
多个根据权利要求1-22任一项所述的附加装置；
多个紧固件，其尺寸设计成并安装以联接到所述流体储存器的本体的至少一个直径以及联接到所述附接点中的至少一个；和
多个保持悬臂，其被配置为将所述多个紧固件可释放地联接到所述支撑板。
28.根据权利要求27所述的套件，其特征在于，所述适配器中的至少一个是无菌的。
29.一种装配用于自注射器的附加装置的方法，其特征在于，包括：
选择空的流体储存器；
通过将所述流体储存器的至少一个尖端联接至根据权利要求1-22任一项所述的附加装置来形成所述一体式自注射器药筒单元；和
在所述流体储存器和所述弯曲的流体路径之间建立流体连通。
30.根据权利要求29所述的方法，其特征在于，还包括：
消毒所述药筒；
用无菌注射剂注入所述流体储存器；
将活塞插入所述流体储存器的无弯曲流体路径端部；以及
无菌地密封所述流体储存器的所述端部。
31.根据权利要求29所述的方法，其特征在于，还包括选择至少一个紧固件并且将所述紧固件联接到所述流体储存器的本体；以及
将所述紧固件联接至所述自注射器的至少一个对应的接触点。
32.一种装配将用于自注射器的附加装置联接到流体储存器的方法，其特征在于，
选择流体储存器；
将所述流体储存器的至少一个尖端联接至根据权利要求1-22任一项所述的附加装置，和
在所述流体储存器和所述弯曲的流体路径之间建立无菌连通。
33.根据权利要求32所述的方法，其特征在于，还包括选择至少一个紧固件并且将所述紧固件联接到所述流体储存器的本体；以及
将所述紧固件联接至所述自注射器的至少一个对应的接触点。
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US15/204,542 US10576207B2 (en) 2015-10-09 2016-07-07 Angled syringe patch injector
US15/269,248 US10086145B2 (en) 2015-09-22 2016-09-19 Rotation resistant friction adapter for plunger driver of drug delivery device
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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997021457A1 (en) * 1995-12-11 1997-06-19 Elan Medical Technologies Limited Cartridge-based drug delivery device

Family Cites Families (888)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1321550A (en) 1919-11-11 Syringe
US232432A (en) 1880-09-21 Coupling for tubes
US1125887A (en) 1914-04-08 1915-01-19 Gustav R Schimmel Hypodermic syringe.
US1704921A (en) 1924-02-11 1929-03-12 Carl C Quale Capsule for hypodermic syringes
US1795530A (en) 1928-01-06 1931-03-10 Watson Waddell Ltd Machine for thrashing and scutching flax
US1795630A (en) 1928-04-24 1931-03-10 Raymond M Ramsey Screw jack
US2453590A (en) 1946-11-04 1948-11-09 Noel J Poux Hypodermic syringe
BE497017A (zh) 1949-11-25
US2702547A (en) 1950-02-27 1955-02-22 Antonina S Glass Motor-driven medical injection apparatus and cartridges therefor
DE855313C (de) 1950-03-31 1952-11-13 August Stoeckert Injektionsspritze
US2677373A (en) 1952-05-19 1954-05-04 P M Ind Inc Plastic injection device
DE1064693B (de) 1956-03-08 1959-09-03 Josef Klinger Vorrichtung zum selbsttaetigen Einstechen einer Injektionsnadel
US2860635A (en) 1957-03-20 1958-11-18 Edgar H Wilburn Sterilizable and sterilized hypodermic syringe assemblies
GB999506A (en) 1960-11-02 1965-07-28 Engis Ltd Improvements in syringes for dispensing paste or the like
US3203269A (en) 1962-10-22 1965-08-31 Lockheed Aircraft Corp Telescoping screw sequencing device
US3623474A (en) 1966-07-25 1971-11-30 Medrad Inc Angiographic injection equipment
US3585439A (en) 1969-06-10 1971-06-15 Westinghouse Electric Corp A camera tube with porous switching layer
BE756550A (fr) 1969-09-23 1971-03-01 Sherwood Medical Ind Inc Seringue a chargement par l'arriere et procede pour son remplissage
US3708945A (en) 1971-01-06 1973-01-09 Upjohn Co Syringe assembling method and machine
US3834387A (en) 1972-08-10 1974-09-10 Sherwood Medical Ind Inc Breech loaded syringe with deformable piston
US3794028A (en) 1973-02-27 1974-02-26 A Griffin Method for injecting chemicals into the papilla for depilation
US3994295A (en) 1975-08-22 1976-11-30 Wulff Goldwyn L Hypodermic syringe needle mounting
DE7603096U1 (de) 1976-02-04 1976-08-19 Espe Pharm Praep Vorrichtung zur dosierten Abgabe viskoser Massen
US4273122A (en) 1976-11-12 1981-06-16 Whitney Douglass G Self contained powered injection system
US4085747A (en) 1976-12-13 1978-04-25 Milstein Medical Research Foundation, Inc. Infusion pumps and dosage control means therefor
US4195636A (en) 1978-03-27 1980-04-01 Behnke Robert C Arm flesh injection site clamp
US4218724A (en) 1978-11-21 1980-08-19 Kaufman Lance R Compact circuit package having improved circuit connectors
US4324262A (en) 1979-01-02 1982-04-13 University Of Virginia Alumni Patents Foundation Aspirating culture catheter and method of use
DE2906830C2 (de) 1979-02-22 1981-07-16 B. Braun Melsungen Ag, 3508 Melsungen Gerät für Dauerinfusionen
US4241381A (en) 1979-04-04 1980-12-23 Amp Incorporated Bus bar assembly for circuit cards
US4254768A (en) 1979-09-14 1981-03-10 Ty Perla J Hypodermic syringe
US4403987A (en) 1982-01-25 1983-09-13 Gottinger Company, Inc. Device for aiding injection of a hypodermic syringe
US4435173A (en) 1982-03-05 1984-03-06 Delta Medical Industries Variable rate syringe pump for insulin delivery
US4425120A (en) 1982-04-15 1984-01-10 Sampson Norma A Shielded hypodermic syringe
US4465478A (en) 1982-10-14 1984-08-14 Collagen Corporation Syringe force amplification device
ATE23802T1 (de) 1982-10-27 1986-12-15 Duphar Int Res Automatische injektionsvorrichtung.
US4710178A (en) 1982-11-03 1987-12-01 Micro-Mega S.A. Precision injection system and method for intraligmental anesthesia
HU189198B (en) 1982-12-10 1986-06-30 Adorjan,Andras,Hu Plastic syringe for single use as well as plastic piston particularly for plastic syringes
US4504263A (en) 1982-12-22 1985-03-12 Valleylab, Inc. Flow rate monitor with optical sensing chamber
US4502488A (en) 1983-01-13 1985-03-05 Allied Corporation Injection system
NZ207354A (en) 1983-05-20 1988-02-29 Bengt Gustavsson Device for transferring fluid without the release of droplets
DE3468173D1 (en) 1983-09-07 1988-02-04 Disetronic Ag Portable infusion apparatus
FR2556214B1 (fr) 1983-12-08 1986-08-14 Merieux Inst Procede de preparation en serie de seringues auto-injectables contenant un medicament lyophilise et dispositif de mise en oeuvre de ce procede
US4549554A (en) 1984-01-03 1985-10-29 Markham Charles W Aspiration biopsy device
US4685903A (en) 1984-01-06 1987-08-11 Pacesetter Infusion, Ltd. External infusion pump apparatus
US4583974A (en) 1984-04-04 1986-04-22 Kokernak Denis T Syringe for balloon dilation catheters
US4601702A (en) 1984-05-21 1986-07-22 Quest Medical, Inc. Volumetric infusion actuator
US4599082A (en) 1984-08-13 1986-07-08 Becton, Dickinson And Company Two-component syringe assembly
US4810215A (en) 1985-06-06 1989-03-07 Yazaki Corporation Position compensating connector
FR2589215B1 (fr) 1985-10-29 1989-05-05 Thomson Csf Joint electrique entre parois conductrices, orthogonales, independantes
US4636201A (en) * 1985-11-01 1987-01-13 American Hospital Supply Corporation Hypodermic syringe having a protective sheath cover
US4695274A (en) 1986-01-31 1987-09-22 Fox Richard L Protected hypodermic needle
DE3606163A1 (de) 1986-02-26 1987-08-27 Hoechst Ag Vorrichtung zur applikation von arzneimittelsuspensionen
US4664654A (en) 1986-03-07 1987-05-12 Strauss Eric C Automatic protracting and locking hypodermic needle guard
US4735311A (en) 1986-04-09 1988-04-05 The West Company Needle shield assembly
US4702738A (en) 1986-05-22 1987-10-27 Spencer Treesa A Disposable hypodermic syringe and needle combination having retractable, accident preventing sheath
DE3638984C3 (de) 1986-11-14 1993-11-18 Haselmeier Wilhelm Fa Injektionsgerät
US4867743A (en) 1986-11-24 1989-09-19 Vaillancourt Vincent L Ambulatory disposable infusion delivery system
US4698055A (en) 1986-11-24 1987-10-06 Sealfon Andrew I Hypodermic syringe
GB8630016D0 (en) 1986-12-16 1987-01-28 Id Tech Ltd Dental injection device
CA1283827C (en) 1986-12-18 1991-05-07 Giorgio Cirelli Appliance for injection of liquid formulations
US4882575A (en) 1987-01-28 1989-11-21 Sharp Kabushiki Kaisha Monitor for blocked condition in tube for fluid infusion pump
US4737144A (en) 1987-03-09 1988-04-12 Choksi Pradip V Syringe with selectively exposed and enveloped needle
US4810249A (en) 1987-03-12 1989-03-07 Habley Medical Technology Corp. Linear and Vernier-type syringe
CA1285441C (en) 1987-03-17 1991-07-02 Roy D. Mcnaughton Mcnaughton syringe shield type b
US4758231A (en) 1987-04-27 1988-07-19 Habley Medical Technology Corporation Shielded safety syringe
NL8701091A (nl) 1987-05-08 1988-12-01 Spruyt Hillen Bv Injectiepen.
US4772272A (en) 1987-05-11 1988-09-20 Mcfarland Barton C Needle protective sleeve
US5080648A (en) 1987-06-08 1992-01-14 Antonio Nicholas F D Hypodermic fluid dispenser
US4813426A (en) 1987-11-09 1989-03-21 Habley Medical Technology Corporation Shielded safety syringe having a retractable needle
US4919596A (en) 1987-12-04 1990-04-24 Pacesetter Infusion, Ltd. Fluid delivery control and monitoring apparatus for a medication infusion system
CH675078A5 (zh) 1988-01-22 1990-08-31 Nosta Ag
US4863434A (en) 1988-01-29 1989-09-05 Bayless William B Automatic needle sheath for disposable syringe
US4840185A (en) 1988-02-17 1989-06-20 Manuel Hernandez Blood sampling device with shield
US4923446A (en) 1988-04-14 1990-05-08 Page Mary J Shield for devices capable of penetrating skin
US4897083A (en) 1988-05-09 1990-01-30 Martell Michael D Syringe needle guard
JPH056995Y2 (zh) 1988-05-27 1993-02-23
US5217437A (en) 1988-06-28 1993-06-08 Sherwood Medical Company Needle protecting device
US5156599A (en) 1988-06-28 1992-10-20 Sherwood Medical Company Syringe and sliding locking needle shield
US5088988A (en) 1988-06-28 1992-02-18 Sherwood Medical Company Combined dental syringe and needle shield
US5127910A (en) 1988-06-28 1992-07-07 Sherwood Medical Company Combined syringe and needle shield and method of manufacture
US5147326A (en) 1988-06-28 1992-09-15 Sherwood Medical Company Combined syringe and needle shield and method of manufacture
US5131816A (en) 1988-07-08 1992-07-21 I-Flow Corporation Cartridge fed programmable ambulatory infusion pumps powered by DC electric motors
US4861341A (en) 1988-07-18 1989-08-29 Woodburn Robert T Subcutaneous venous access device and needle system
US4892521A (en) 1988-08-03 1990-01-09 Lincoln Mills, Inc. Protective cover for hypodermic needle
US4929241A (en) 1988-08-05 1990-05-29 Kulli John C Medical needle puncture guard
US4900310A (en) 1988-10-07 1990-02-13 International Medication Systems Limited Protective device for cannula used to draw blood
US4919569A (en) 1988-11-10 1990-04-24 Wittenzellner Siegfried Process for disposing of waste
US4950241A (en) 1988-12-27 1990-08-21 Sherwood Medical Company Disposable syringe
DK68789A (da) 1989-02-14 1990-08-15 Novo Nordisk As Injektionspen
US5019051A (en) 1989-03-02 1991-05-28 Needlepoint Guard, Inc. Hypodermic needle guard
US5062828A (en) 1989-03-13 1991-11-05 Waltz Roger L Hypodermic syringe
IT1231916B (it) 1989-05-29 1992-01-15 Ampliscientifica S R L Pancreas artificiale indossabile
US4998924A (en) 1989-07-25 1991-03-12 Sherwood Medical Company Double sleeve safety syringe
USD322671S (en) 1989-11-22 1991-12-24 Becton, Dickinson And Company Needle shield or the like
US4964866A (en) 1989-11-22 1990-10-23 Becton, Dickinson And Company Needle sheath assembly
US5109850A (en) 1990-02-09 1992-05-05 Massachusetts Institute Of Technology Automatic blood monitoring for medication delivery method and apparatus
US4994045A (en) 1990-04-20 1991-02-19 Sherwood Medical Company Split sleeve safety syringe
US5624400A (en) 1990-05-09 1997-04-29 Safety Syringes, Inc. Disposable self-shielding aspirating syringe
US5051109A (en) 1990-07-16 1991-09-24 Simon Alexander Z Protector for catheter needle
US5190521A (en) 1990-08-22 1993-03-02 Tecnol Medical Products, Inc. Apparatus and method for raising a skin wheal and anesthetizing skin
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
TW279133B (zh) 1990-12-13 1996-06-21 Elan Med Tech
US5298023A (en) 1991-03-08 1994-03-29 Habley Medical Technology Corporation Multiple pharmaceutical dispenser with accumulator
AU654857B2 (en) 1991-03-29 1994-11-24 Collagen Corporation Device and method for treating facial lines
JPH0562828A (ja) 1991-08-30 1993-03-12 Railway Technical Res Inst 可動式磁場低減装置
DK175491D0 (da) 1991-10-18 1991-10-18 Novo Nordisk As Apparat
AT397467B (de) 1991-10-22 1994-04-25 Wimmer Erwin Einwegspritze
US5300119A (en) 1992-01-10 1994-04-05 Hansa Medical Products, Inc. Delivery system
US5269762A (en) 1992-04-21 1993-12-14 Sterling Winthrop, Inc. Portable hand-held power assister device
US5295966A (en) 1992-04-29 1994-03-22 Becton, Dickinson And Company Syringe pump with biased lockable syringe clamp
US5282593A (en) 1992-06-05 1994-02-01 Tri W-G, Inc. Adjustable leg
EP0598867B1 (de) 1992-06-15 1997-03-05 WYSSMANN, Max Vorrichtung zur gezielten, steuerbaren abgabe einer flüssigkeit oder einer viskosen masse
US5254096A (en) 1992-09-23 1993-10-19 Becton, Dickinson And Company Syringe pump with graphical display or error conditions
US5246670A (en) 1992-09-23 1993-09-21 Habley Medical Technology Corporation Pharmaceutical mixing container with buoyant mixing element
US5376785A (en) 1992-10-02 1994-12-27 Chin; Philip K. Optical displacement sensor utilizing optical diffusion
IL107038A (en) 1992-10-05 1997-04-15 Senetek Plc Medicament injectors and methods for injection using same
US5267977A (en) 1992-10-29 1993-12-07 Feeney Jr Richard J No-stick syringe
US5342313A (en) 1992-11-02 1994-08-30 Infusion Technologies Corporation Fluid pump for a flexible, variable geometry reservoir
US5496274A (en) 1992-11-23 1996-03-05 Becton, Dickinson And Company Locking safety needle assembly
CH685461B5 (fr) 1993-01-05 1996-01-31 Jean Claude Berney Dispositif portable de perfusion de substances therapeutiques liquides et ensembles comprenant un tel dispositif.
ATE155439T1 (de) 1993-01-29 1997-08-15 Schering Plough Healthcare Stabile sulfidepräperate, deren anwendung und herstellung
AU682670B2 (en) 1993-02-05 1997-10-16 Becton Dickinson & Company Syringe needle isolation device
US5383865A (en) 1993-03-15 1995-01-24 Eli Lilly And Company Medication dispensing device
US5894015A (en) 1993-04-07 1999-04-13 Rechtin; Michael D. Disinfection of medical sharps
US5300045A (en) 1993-04-14 1994-04-05 Plassche Jr Walter M Interventional needle having an automatically capping stylet
JP3199524B2 (ja) 1993-08-06 2001-08-20 日本メジフィジックス株式会社 ルアーニードルユニット及び注射器
US5338311A (en) 1993-08-23 1994-08-16 Mahurkar Sakharam D Hypodermic needle assembly
FR2710537B1 (fr) 1993-09-30 1995-12-01 Becton Dickinson Co Procédé et dispositif de détection d'occlusions dans une ligne de perfusion.
USD356150S (en) 1993-10-04 1995-03-07 Abbott Laboratories Container closure with drip chamber
SE9303568D0 (sv) 1993-10-29 1993-10-29 Kabi Pharmacia Ab Improvements in injection devices
US5348544A (en) 1993-11-24 1994-09-20 Becton, Dickinson And Company Single-handedly actuatable safety shield for needles
JP3223684B2 (ja) 1993-12-31 2001-10-29 ニプロ株式会社 薬液注入器具
US5478316A (en) 1994-02-02 1995-12-26 Becton, Dickinson And Company Automatic self-injection device
US5804331A (en) 1994-02-15 1998-09-08 Mag Instrument, Inc. Battery device
US5645955A (en) 1994-02-15 1997-07-08 Mag Instrument, Inc. Battery
US5522804A (en) 1994-02-15 1996-06-04 Lynn; Lawrence A. Aspiration, mixing, and injection syringe
US5482446A (en) 1994-03-09 1996-01-09 Baxter International Inc. Ambulatory infusion pump
US5536249A (en) 1994-03-09 1996-07-16 Visionary Medical Products, Inc. Pen-type injector with a microprocessor and blood characteristic monitor
US5415645A (en) 1994-04-29 1995-05-16 Friend; John M. Retractable sheath for hypodermic needle
EP0680767A1 (en) 1994-05-06 1995-11-08 Nardino Righi Non-reusable safety syringe
GB2301035A (en) 1994-05-30 1996-11-27 Carlos Maria Baron Non-resusable syringe
US5478315A (en) 1994-08-08 1995-12-26 Brothers Family Investments, L.C. Local anesthetic injection system
US5658256A (en) 1994-08-22 1997-08-19 Shields; Jack W. Universal sharps shield
CN1063670C (zh) 1994-09-07 2001-03-28 陈隆雄 一种安全型注射器
US5505709A (en) 1994-09-15 1996-04-09 Minimed, Inc., A Delaware Corporation Mated infusion pump and syringe
US5609580A (en) 1994-09-16 1997-03-11 Vital Signs, Inc. Injection holder for a plungerless syringe and combination plungerless syringe and injection holder
GB9419316D0 (en) 1994-09-24 1994-11-09 Robertson William F A needle guard
US7027859B1 (en) 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
US5456360A (en) * 1994-09-30 1995-10-10 The Perkin-Elmer Corporation Holder assembly for reaction tubes
CA2159052C (en) 1994-10-28 2007-03-06 Rainer Alex Injection device
IE72524B1 (en) 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US5743879A (en) 1994-12-02 1998-04-28 Science Incorporated Medicament dispenser
US5637095A (en) 1995-01-13 1997-06-10 Minimed Inc. Medication infusion pump with flexible drive plunger
GB9501218D0 (en) 1995-01-21 1995-03-15 Boc Group Plc Medical devices
US5690618A (en) 1995-02-22 1997-11-25 Mark Timothy Smith Electronic syringe
US5647853A (en) 1995-03-03 1997-07-15 Minimed Inc. Rapid response occlusion detector for a medication infusion pump
IL114960A0 (en) 1995-03-20 1995-12-08 Medimop Medical Projects Ltd Flow control device
US5562686A (en) 1995-04-19 1996-10-08 United States Surgical Corporation Apparaus and method for suturing body tissue
PT821600E (pt) 1995-04-20 2004-04-30 Acist Medical Sys Inc Injector angiografico autopurgante
GB9511169D0 (en) 1995-06-02 1995-07-26 Lilly Co Eli Containers for liquid medicaments
CA2151407A1 (en) 1995-06-09 1996-12-10 Duncan Newman Injection device
WO1997000091A1 (fr) 1995-06-14 1997-01-03 Berney Jean Claude Piston de seringue avec transmission lineaire
US5645530A (en) 1995-08-28 1997-07-08 Alcon Laboratories, Inc. Phacoemulsification sleeve
CA2231542A1 (en) 1995-09-11 1997-03-20 Elan Medical Technologies Limited Medicament delivery device
IE77523B1 (en) 1995-09-11 1997-12-17 Elan Med Tech Medicament delivery device
US5776103A (en) 1995-10-11 1998-07-07 Science Incorporated Fluid delivery device with bolus injection site
US6277095B1 (en) 1995-10-11 2001-08-21 Science Incorporated Fluid delivery device with full adapter
US5989221A (en) 1995-10-20 1999-11-23 Pharmacia & Upjohn Ab Arrangement in electronically controlled injection devices
US5697916A (en) 1995-11-21 1997-12-16 Stat Medical Devices Inc. Hypodermic dosage measuring device
US5830187A (en) 1995-12-22 1998-11-03 Science Incorporated Fluid delivery device with conformable ullage and fill assembly
PT918554E (pt) 1996-03-12 2006-05-31 Novo Nordisk As Dispositivo de injeccao com apresentacao electronica das doses determinadas
GB9606829D0 (en) 1996-03-30 1996-06-05 Jeffrey Peter Supplying materials etc
US7468055B2 (en) 1996-06-20 2008-12-23 Becton Dickinson And Company Multi-beveled point needle and syringe having a multi-beveled point needle
US5858008A (en) 1997-04-22 1999-01-12 Becton, Dickinson And Company Cannula sealing shield assembly
JP3531149B2 (ja) 1996-07-31 2004-05-24 ニプロ株式会社 採血針廃棄容器
USD393314S (en) 1996-08-28 1998-04-07 Medisense, Inc. Meter for analysis of blood constituents
JP3035448U (ja) 1996-09-04 1997-03-18 株式会社ジーシー 歯周ポケット用薬剤注入器
US5697908A (en) 1996-09-26 1997-12-16 Becton Dickinson France, S.A. Lockable safety shield for a prefillable syringe
US6146361A (en) 1996-09-26 2000-11-14 Becton Dickinson And Company Medication delivery pen having a 31 gauge needle
US5662678A (en) 1996-10-11 1997-09-02 Macklin; John W. Self injection arm clamp
US5868710A (en) 1996-11-22 1999-02-09 Liebel Flarsheim Company Medical fluid injector
US5766186A (en) 1996-12-03 1998-06-16 Simon Fraser University Suturing device
WO1998033538A1 (en) 1997-02-04 1998-08-06 Novo Nordisk A/S A device for the administration of a liquid medicament suspension
US5851197A (en) 1997-02-05 1998-12-22 Minimed Inc. Injector for a subcutaneous infusion set
US7899511B2 (en) 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
DE19717107B4 (de) 1997-04-23 2005-06-23 Disetronic Licensing Ag System aus Behältnis und Antriebsvorrichtung für einen Kolben, der in dem ein Medikamentfluid enthaltenden Behältnis gehalten ist
US6186982B1 (en) 1998-05-05 2001-02-13 Elan Corporation, Plc Subcutaneous drug delivery device with improved filling system
US6530900B1 (en) 1997-05-06 2003-03-11 Elan Pharma International Limited Drug delivery device
EA010183B1 (ru) 1997-05-14 2008-06-30 Атеродженикс, Инк. Сложный моноэфир янтарной кислоты и пробукола для лечения сердечно-сосудистых и воспалительных заболеваний
US6558351B1 (en) 1999-06-03 2003-05-06 Medtronic Minimed, Inc. Closed loop system for controlling insulin infusion
US6500150B1 (en) * 1997-06-16 2002-12-31 Elan Pharma International Limited Pre-filled drug-delivery device and method of manufacture and assembly of same
ATE274938T1 (de) 1997-06-16 2004-09-15 Elan Corp Plc Vorgefüllte medikamentenabgabevorrichtung
US5961496A (en) 1997-06-17 1999-10-05 Novo Nordisk A/S Syringe with tiltable nut for quick piston disengagement
US5968011A (en) 1997-06-20 1999-10-19 Maersk Medical A/S Subcutaneous injection set
EP1015050A1 (en) 1997-07-11 2000-07-05 Novo Nordisk A/S An apparatus for the registration of the setting of a medical device
US5944699A (en) 1997-08-11 1999-08-31 Barrelle; Laurent Pre-assembled syringe
US5810784A (en) 1997-08-15 1998-09-22 Tamaro; Frank A. Safety cap assembly for needles and catheters
DE20103363U1 (de) * 2001-02-26 2001-05-17 Braun Melsungen Ag Schutzvorrichtung für eine Injektionsnadel
CN1127357C (zh) 1997-09-16 2003-11-12 黄吴顺 具定位的静脉注射安全针筒
US6004296A (en) 1997-09-30 1999-12-21 Becton Dickinson France, S.A. Lockable safety shield assembly for a prefillable syringe
FR2770136B1 (fr) 1997-10-27 2000-03-10 Njc Innovations Dispositif d'administration de substances therapeutiques a seringue motorisee
US5984697A (en) 1997-12-03 1999-11-16 Qualcomm Incorporated Ground clip apparatus for circuit boards
US6033245A (en) 1997-12-05 2000-03-07 Simplex Time Recorder Co. Self-aligning electrical connector
JP4647098B2 (ja) 1997-12-31 2011-03-09 メドトロニック ミニメド インコーポレイテッド 挿入セットのための挿入装置
US5926596A (en) 1998-01-28 1999-07-20 The Whitaker Corporation Overmolded alignment ferrule
HU222513B1 (hu) 1998-01-30 2003-08-28 Novo Nordisk A/S Injekciós fecskendő
US5957895A (en) 1998-02-20 1999-09-28 Becton Dickinson And Company Low-profile automatic injection device with self-emptying reservoir
US5954697A (en) 1998-03-02 1999-09-21 Srisathapat; Chad Threaded nut syringe plunger for use with a medication infusion pump
EP1433705B1 (en) 1998-03-13 2015-07-22 Becton Dickinson and Company Method for manufacturing, filling and packaging medical containers
US6186979B1 (en) 1998-03-16 2001-02-13 Edward D. Dysarz One-handed retractable blood collection device with trap-in container
ATE254938T1 (de) 1998-03-23 2003-12-15 Elan Corp Plc Vorrichtung zur arzneimittelverarbreichung
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US5919167A (en) 1998-04-08 1999-07-06 Ferring Pharmaceuticals Disposable micropump
US6200289B1 (en) 1998-04-10 2001-03-13 Milestone Scientific, Inc. Pressure/force computer controlled drug delivery system and the like
TW406018B (en) 1998-05-21 2000-09-21 Elan Corp Plc Improved adhesive system for medical devices
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US5941850A (en) 1998-06-29 1999-08-24 Shah; Binod Safety cannula
US6554798B1 (en) 1998-08-18 2003-04-29 Medtronic Minimed, Inc. External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities
US5993423A (en) 1998-08-18 1999-11-30 Choi; Soo Bong Portable automatic syringe device and injection needle unit thereof
JP2000107289A (ja) 1998-10-05 2000-04-18 Showa Yakuhin Kako Kk カートリッジ式歯科用注射器ユニット
US6064797A (en) 1998-10-12 2000-05-16 B. Braun Medical, Inc. Volumetric flow equalizing drive control wheel
SE9803662D0 (sv) 1998-10-26 1998-10-26 Pharmacia & Upjohn Ab Autoinjector
US20050197626A1 (en) 1998-10-29 2005-09-08 Medtronic Minimed Inc. Fluid reservoir for use with an external infusion device
US7193521B2 (en) 1998-10-29 2007-03-20 Medtronic Minimed, Inc. Method and apparatus for detecting errors, fluid pressure, and occlusions in an ambulatory infusion pump
US6817990B2 (en) 1998-10-29 2004-11-16 Medtronic Minimed, Inc. Fluid reservoir piston
US6800071B1 (en) 1998-10-29 2004-10-05 Medtronic Minimed, Inc. Fluid reservoir piston
US20020173748A1 (en) 1998-10-29 2002-11-21 Mcconnell Susan Reservoir connector
ATE498422T1 (de) 1998-10-29 2011-03-15 Medtronic Minimed Inc Reservoiranschluss
US6248093B1 (en) 1998-10-29 2001-06-19 Minimed Inc. Compact pump drive system
US7621893B2 (en) 1998-10-29 2009-11-24 Medtronic Minimed, Inc. Methods and apparatuses for detecting occlusions in an ambulatory infusion pump
US7766873B2 (en) 1998-10-29 2010-08-03 Medtronic Minimed, Inc. Method and apparatus for detecting occlusions in an ambulatory infusion pump
US6907679B2 (en) 1998-11-12 2005-06-21 Qlt Usa, Inc. Method for lyophilizing an active agent
US6645181B1 (en) 1998-11-13 2003-11-11 Elan Pharma International Limited Drug delivery systems and methods
US6162197A (en) 1998-12-22 2000-12-19 Mohammad; Owais Retractable needle assembly and method of making the same
US20010018937A1 (en) 1998-12-28 2001-09-06 Shigeru Nemoto Method and device for pre-filling a syringe with a contrast agent
US6645177B1 (en) 1999-02-09 2003-11-11 Alaris Medical Systems, Inc. Directly engaged syringe driver system
US6423029B1 (en) 1999-04-29 2002-07-23 Medtronic, Inc. System and method for detecting abnormal medicament pump fluid pressure
US6336729B1 (en) 1999-05-20 2002-01-08 Richard Pavelle Emergency light device
US6458102B1 (en) 1999-05-28 2002-10-01 Medtronic Minimed, Inc. External gas powered programmable infusion device
US7806886B2 (en) 1999-06-03 2010-10-05 Medtronic Minimed, Inc. Apparatus and method for controlling insulin infusion with state variable feedback
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6752787B1 (en) 1999-06-08 2004-06-22 Medtronic Minimed, Inc., Cost-sensitive application infusion device
US6270481B1 (en) 1999-06-16 2001-08-07 Breg, Inc. Patient-controlled medication delivery system
US6277099B1 (en) 1999-08-06 2001-08-21 Becton, Dickinson And Company Medication delivery pen
US6377848B1 (en) 1999-08-25 2002-04-23 Vyteris, Inc. Devices activating an iontophoretic delivery device
US6224569B1 (en) 1999-09-24 2001-05-01 Becton, Dickinson And Company Compact needle point shield
AU7839900A (en) 1999-09-29 2001-04-30 Sterling Medivations, Inc. Reusable medication delivery device
US20020193740A1 (en) 1999-10-14 2002-12-19 Alchas Paul G. Method of intradermally injecting substances
US6383173B1 (en) 1999-10-22 2002-05-07 Roy H. Hunt Syringe drench adapter for livestock
US7063684B2 (en) 1999-10-28 2006-06-20 Medtronic Minimed, Inc. Drive system seal
US6394984B1 (en) 1999-10-28 2002-05-28 Frank C Hill Syringe
US6520930B2 (en) 1999-11-24 2003-02-18 Medrad, Inc. Injectors, injector systems and injector control
US6673033B1 (en) 1999-11-24 2004-01-06 Medrad, Inc. Injectors, injector systems and injector control
US6958053B1 (en) 1999-11-24 2005-10-25 Medrad, Inc. Injector providing drive member advancement and engagement with syringe plunger, and method of connecting a syringe to an injector
US6302633B1 (en) 1999-12-17 2001-10-16 L. Richard Poe Multiple pitch threaded fastener apparatus
US20030060765A1 (en) 2000-02-16 2003-03-27 Arthur Campbell Infusion device menu structure and method of using the same
DE10012575A1 (de) 2000-03-15 2001-09-27 Schott Glas Transportvorrichtung für medizinische Behälter
WO2001070304A1 (en) * 2000-03-22 2001-09-27 Docusys, Inc. A drug delivery and monitoring system
US20010041869A1 (en) 2000-03-23 2001-11-15 Causey James D. Control tabs for infusion devices and methods of using the same
US6485465B2 (en) 2000-03-29 2002-11-26 Medtronic Minimed, Inc. Methods, apparatuses, and uses for infusion pump fluid pressure and force detection
US6836687B2 (en) 2000-03-31 2004-12-28 Medtronic, Inc. Method and system for delivery of a medical electrical lead within a venous system
US6485461B1 (en) 2000-04-04 2002-11-26 Insulet, Inc. Disposable infusion device
US6716198B2 (en) 2000-05-18 2004-04-06 Novo Nordisk A/S Injection device
SE0001893D0 (sv) 2000-05-22 2000-05-22 Pharmacia & Upjohn Ab Medical arrangement
US6511336B1 (en) 2000-05-25 2003-01-28 Illinois Tool Works Inc. Solderless flex termination for motor tab
DE10026172A1 (de) 2000-05-26 2001-11-29 Roche Diagnostics Gmbh System zur Entnahme von Körperflüssigkeit
US6517517B1 (en) 2000-06-08 2003-02-11 Mayo Foundation For Medical Education And Research Automated injection device for administration of liquid medicament
US7530964B2 (en) 2000-06-30 2009-05-12 Elan Pharma International Limited Needle device and method thereof
AUPQ867900A0 (en) 2000-07-10 2000-08-03 Medrad, Inc. Medical injector system
US6589229B1 (en) 2000-07-31 2003-07-08 Becton, Dickinson And Company Wearable, self-contained drug infusion device
US6986760B2 (en) 2000-08-02 2006-01-17 Becton, Dickinson And Company Pen needle and safety shield system
US6554800B1 (en) 2000-08-09 2003-04-29 Medtronic Minimed, Inc. Compact pump motor system and dispensing process
US6652482B2 (en) 2000-08-17 2003-11-25 Milestone Scientific Inc Dental anesthetic and delivery injection unit with automated rate control
CN1471413A (zh) 2000-09-08 2004-01-28 用于患者注射的装置、系统和方法
US20040260233A1 (en) 2000-09-08 2004-12-23 Garibotto John T. Data collection assembly for patient infusion system
AU2001296588B2 (en) 2000-10-04 2006-06-08 Insulet Corporation Data collection assembly for patient infusion system
JP2002191695A (ja) 2000-10-20 2002-07-09 Mitsubishi Pencil Co Ltd 針先カバー部材、針先カバー部材付き注射針の組立方法、針ガード部材付き注射針および針ガード部材付き注射器
EP1333872A1 (en) 2000-10-27 2003-08-13 Novo Nordisk A/S A medication delivery device with telescopic piston rod
US6508788B2 (en) 2000-10-27 2003-01-21 Novo Nordisk A/S Medication delivery device with telescopic piston rod
US6572604B1 (en) 2000-11-07 2003-06-03 Baxter International Inc. Occlusion detection method and system for ambulatory drug infusion pump
CN101264357A (zh) 2000-11-09 2008-09-17 茵斯莱特有限公司 经皮给药装置
AU2002241567A1 (en) 2000-11-30 2002-07-24 Biovalve Technologies, Inc. Fluid delivery and measurement systems and methods
USD461243S1 (en) 2000-12-04 2002-08-06 Bracco Diagnostics Inc. Ellipsoidal syringe barrel
US20020086036A1 (en) 2000-12-05 2002-07-04 Allergan Sales, Inc. Methods for treating hyperhidrosis
US6387078B1 (en) 2000-12-21 2002-05-14 Gillespie, Iii Richard D. Automatic mixing and injecting apparatus
JP2004532664A (ja) 2000-12-21 2004-10-28 インシュレット コーポレイション 医療機器の遠隔制御装置及び方法
IT1320868B1 (it) 2000-12-29 2003-12-10 Cane Srl Dispositivo portatile per infusione di farmaci.
US6666821B2 (en) 2001-01-08 2003-12-23 Medtronic, Inc. Sensor system
DE10101932A1 (de) 2001-01-17 2002-07-25 Disetronic Licensing Ag Ansaugstück für eine oder an einer Vorrichtung zur Verabreichung eines injizierbaren Produkts
US6743237B2 (en) 2001-01-17 2004-06-01 Innon Holdings, Llc Endoscopic stone extraction device with improved basket
US7018363B2 (en) 2001-01-18 2006-03-28 Medrad, Inc. Encoding and sensing of syringe information
US6905298B1 (en) 2001-02-08 2005-06-14 Joseph E. Haring Telescopic nut
WO2002068015A2 (en) 2001-02-22 2002-09-06 Insulet Corporation Modular infusion device and method
CA2431049C (en) 2001-02-23 2010-06-01 Stryker Instruments Integrated medication delivery system
US20040034331A1 (en) 2001-02-23 2004-02-19 Jason Toman Integrated medication delivery system
AUPR373001A0 (en) 2001-03-14 2001-04-12 Glenord Pty Ltd Improved non-reusable syringe
GB0107604D0 (en) 2001-03-27 2001-05-16 Dca Design Int Ltd Improvements in and relating to injection device
EP1385571B1 (en) 2001-04-04 2008-07-30 Alza Corporation Transdermal electrotransport delivery device including an antimicrobial compatible reservoir composition
US6595960B2 (en) 2001-04-12 2003-07-22 Becton, Dickinson And Company Flexible needle assembly
US20020161332A1 (en) 2001-04-13 2002-10-31 Kirk Ramey Infusion set with tape
US6854620B2 (en) 2001-04-13 2005-02-15 Nipro Diabetes, Systems, Inc. Drive system for an infusion pump
CA2689022C (en) 2001-05-16 2012-09-18 Eli Lilly And Company Medication injector apparatus with drive assembly that facilitates reset
US7306578B2 (en) 2002-01-04 2007-12-11 Deka Products Limited Partnership Loading mechanism for infusion pump
ATE352334T1 (de) 2001-05-18 2007-02-15 Deka Products Lp Infusionsvorrichtung für eine flüssigkeitspumpe
US8034026B2 (en) 2001-05-18 2011-10-11 Deka Products Limited Partnership Infusion pump assembly
US20120209197A1 (en) 2002-01-04 2012-08-16 Lanigan Richard J Infusion pump assembly
WO2002094340A2 (en) 2001-05-22 2002-11-28 Becton, Dickinson And Company Needle shield assembly having hinged needle shield
US7308300B2 (en) 2001-05-30 2007-12-11 Acist Medical Systems, Inc. Medical injection system
US6767341B2 (en) 2001-06-13 2004-07-27 Abbott Laboratories Microneedles for minimally invasive drug delivery
US7214207B2 (en) 2002-03-08 2007-05-08 Applied Diabetes Research, Inc. Low profile, pivotal connection infusion assembly
US6565541B2 (en) 2001-07-18 2003-05-20 Inviro Medical Devices Ltd. Cannula guard and cannula for a syringe
DK1436020T3 (da) 2001-07-27 2008-09-01 Becton Dickinson Co Luerkoblingssamling
DE10163325B4 (de) 2001-07-30 2005-07-28 Tecpharma Licensing Ag Verriegelungssperre für eine Verbindung von Gehäuseabschnitten eines Verabreichungsgeräts
DE10163328B4 (de) 2001-07-30 2005-08-11 Tecpharma Licensing Ag Verabreichungsgerät mit Verdrehsicherung
CH695288A5 (de) 2001-08-21 2006-03-15 Tecpharma Licensing Ag Befestigungsvorrichtung fuer Injektionsnadeln.
US6722916B2 (en) 2001-08-30 2004-04-20 Siemens Vdo Automotive Corporation Surface battery clip
USD471983S1 (en) 2001-09-04 2003-03-18 Hypoguard Limited Blood glucose meter
US6827702B2 (en) 2001-09-07 2004-12-07 Medtronic Minimed, Inc. Safety limits for closed-loop infusion pump control
US8152789B2 (en) 2001-10-23 2012-04-10 Medtronic Minimed, Inc. System and method for providing closed loop infusion formulation delivery
US7556615B2 (en) 2001-09-12 2009-07-07 Becton, Dickinson And Company Microneedle-based pen device for drug delivery and method for using same
US20060122577A1 (en) 2001-09-26 2006-06-08 Poulsen Jens U Modular drug delivery system
US6572565B2 (en) 2001-10-10 2003-06-03 Maxxon, Inc. Blood sampling assembly with a retractable needle
FR2830765B1 (fr) 2001-10-15 2004-07-23 Plastic Omnium Cie Dispositif de securite pour une seringue
US7549977B2 (en) 2002-12-20 2009-06-23 Medrad, Inc. Front load pressure jacket system with syringe holder and light illumination
USD465026S1 (en) 2001-11-13 2002-10-29 Hypoguard Limited Blood glucose meter
US7291126B2 (en) 2001-11-26 2007-11-06 Nilimedix Ltd. Drug delivery device and method
US7311693B2 (en) 2001-11-26 2007-12-25 Nilimedix Ltd. Drug delivery device and method
GB0129171D0 (en) 2001-12-06 2002-01-23 Dca Design Int Ltd Improvements in and relating to a medicament cartridge
US7204823B2 (en) 2001-12-19 2007-04-17 Medtronic Minimed, Inc. Medication delivery system and monitor
US7247149B2 (en) 2001-12-20 2007-07-24 Advanced Cardiovascular Systems, Inc. Contact and penetration depth sensor for a needle assembly
JP3763141B2 (ja) 2001-12-28 2006-04-05 ニプロ株式会社 シリンジ型薬液容器
ITTO20011228A1 (it) 2001-12-28 2003-06-28 Cane Srl Contenitore per ago monouso.
US6786890B2 (en) 2002-01-25 2004-09-07 Novo Nordisk A/S Linear actuator and a medical delivery device comprising such linear actuator
GB0201689D0 (en) 2002-01-25 2002-03-13 Dca Design Consultants Ltd Improvements in and relating to a medicament injection device
ATE310185T1 (de) 2002-01-25 2005-12-15 Novo Nordisk As Linearantrieb und medizinische abgabevorrichtung mit einem solchen linearantrieb
AU2003209095A1 (en) 2002-02-11 2003-09-04 Antares Pharma, Inc. Intradermal injector
USD471274S1 (en) 2002-02-23 2003-03-04 Stryker Instruments Medication delivery pump
US7267669B2 (en) 2002-02-23 2007-09-11 Stryker Corporation Two site infusion apparatus
US7041082B2 (en) 2002-02-28 2006-05-09 Smiths Medical Md, Inc. Syringe pump control systems and methods
US6744350B2 (en) 2002-02-28 2004-06-01 Smiths Medical Md, Inc. Insulin pump having missed meal bolus alarm
US7033338B2 (en) 2002-02-28 2006-04-25 Smiths Medical Md, Inc. Cartridge and rod for axially loading medication pump
US6805687B2 (en) 2002-03-22 2004-10-19 Codman & Shurtleff, Inc. Infusion pump with access regulator
US7004929B2 (en) 2002-03-29 2006-02-28 Mdc Investment Holdings, Inc. Safety pre-filled cartridge injector
US7052251B2 (en) 2002-04-22 2006-05-30 Medtronic Minimed, Inc. Shape memory alloy wire driven positive displacement micropump with pulsatile output
US20050238507A1 (en) 2002-04-23 2005-10-27 Insulet Corporation Fluid delivery device
US6656158B2 (en) 2002-04-23 2003-12-02 Insulet Corporation Dispenser for patient infusion device
US6960192B1 (en) 2002-04-23 2005-11-01 Insulet Corporation Transcutaneous fluid delivery system
US6656159B2 (en) 2002-04-23 2003-12-02 Insulet Corporation Dispenser for patient infusion device
US7476217B2 (en) 2002-05-02 2009-01-13 Cilag Gmbh International Injection device
US6776777B2 (en) 2002-05-10 2004-08-17 Becton, Dickinson And Company Passive safety shield system for injection devices
US6979316B1 (en) 2002-05-23 2005-12-27 Seedlings Life Science Ventures Llc Apparatus and method for rapid auto-injection of medication
WO2003099357A1 (en) 2002-05-24 2003-12-04 Eli Lilly And Company Medication injecting apparatus with fluid container piston-engaging drive member having internal hollow for accommodating drive member shifting mechanism
US20030236489A1 (en) 2002-06-21 2003-12-25 Baxter International, Inc. Method and apparatus for closed-loop flow control system
GB0214452D0 (en) 2002-06-22 2002-07-31 Liversidge Barry P Medical needle assemblies
US7338465B2 (en) 2002-07-02 2008-03-04 Patton Medical Devices, Lp Infusion device and method thereof
US6752783B2 (en) 2002-07-10 2004-06-22 Ming-Kan Hung Safety device for syringe
US20040010207A1 (en) 2002-07-15 2004-01-15 Flaherty J. Christopher Self-contained, automatic transcutaneous physiologic sensing system
WO2004032990A2 (en) 2002-07-22 2004-04-22 Becton, Dickinson And Company Patch-like infusion device
DE60310233T2 (de) 2002-07-24 2007-09-13 Deka Products Ltd. Partnership Optischer verschiebungssensor für infusionsgeräte
US7740600B2 (en) 2002-08-02 2010-06-22 Candela Corporation Apparatus and method for inhibiting pain signals transmitted during a skin related medical treatment
US20040049160A1 (en) 2002-09-10 2004-03-11 Chung-Chieh Hsieh Safety hypodermic syringe
CN1723053A (zh) 2002-09-12 2006-01-18 儿童医院医疗中心 无痛药物注射的方法和设备
US7435238B2 (en) 2002-09-13 2008-10-14 Alan Reid Needle device having retractable needle providing enhanced safety
DE10242984B4 (de) 2002-09-17 2010-09-23 Sanatis Gmbh Vorrichtung zum Herstellen von Gemischen aus zwei Komponenten
ES2327731T3 (es) 2002-09-24 2009-11-03 Shl Group Ab Dispositivo de inyeccion.
US7128727B2 (en) 2002-09-30 2006-10-31 Flaherty J Christopher Components and methods for patient infusion device
US7144384B2 (en) 2002-09-30 2006-12-05 Insulet Corporation Dispenser components and methods for patient infusion device
WO2005061041A1 (en) 2002-10-11 2005-07-07 Becton, Dickinson And Company Insulin delivery system with sensor
US20040082911A1 (en) 2002-10-25 2004-04-29 Bruce Tiu Syringe having needle safely receiving structure
DE10255133B3 (de) 2002-11-26 2004-04-08 Disetronic Licensing Ag Einführvorrichtung für Nadeleinheiten
US20040116866A1 (en) 2002-12-17 2004-06-17 William Gorman Skin attachment apparatus and method for patient infusion device
WO2004057959A2 (en) 2002-12-20 2004-07-15 Generipharm, Inc. Intracutaneous injection
US6846302B2 (en) 2002-12-31 2005-01-25 Teva Medical Ltd. Needle protector device
US6767336B1 (en) 2003-01-09 2004-07-27 Sheldon Kaplan Automatic injector
CA2513029A1 (en) 2003-01-16 2004-08-05 John M. Brittingham Intradermal cellular delivery using narrow gauge micro-cannula
US20090204076A1 (en) 2003-02-03 2009-08-13 Barry Peter Liversidge Medical Injector
US7229419B2 (en) 2003-02-11 2007-06-12 Promex/U.S. Biosy Llc Single-handed biopsy system
US8490790B2 (en) 2003-02-24 2013-07-23 Becton Dickinson France S.A.S. Plate for holding a group of syringe body objects
US7225694B2 (en) 2003-03-03 2007-06-05 Lockheed Martin Corporation Telescopic actuator
GB0304824D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
GB0304823D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
US7390314B2 (en) 2003-03-05 2008-06-24 Medtronic Minimed, Inc. Lead screw driven reservoir with integral plunger nut and method of using the same
US6997727B1 (en) 2003-03-14 2006-02-14 Zierick Manufacturing Corp Compliant surface mount electrical contacts for circuit boards and method of making and using same
CA2433205A1 (en) 2003-03-18 2004-09-18 James Alexander Keenan Drug delivery, bodily fluid drainage, and biopsy device with enhanced ultrasonic visibility
EP1613377A1 (en) 2003-04-16 2006-01-11 Allergan, Inc. Controlled volume injection/aspiration device
CA2520880A1 (en) 2003-04-18 2004-11-04 Insulet Corporation User interface for infusion pump remote controller and method of using the same
ATE457761T1 (de) 2003-05-08 2010-03-15 Novo Nordisk As Schwenkbare vorrichtung für eine injektionsnadel
EP1624913B1 (en) 2003-05-08 2010-07-21 Novo Nordisk A/S Skin mountable injection device with a detachable needle insertion actuation portion
EP1475113A1 (en) 2003-05-08 2004-11-10 Novo Nordisk A/S External needle inserter
CA2526597C (en) 2003-05-29 2011-05-17 Adam Bloom Syringe with locking member
US7500963B2 (en) 2003-07-22 2009-03-10 Safety Syringes, Inc. Systems and methods for automatic medical injection with safeguard
US20050027255A1 (en) 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
EP1660158B1 (en) 2003-07-31 2008-12-24 Sid Technologies Llc Syringe with automatically triggered safety sleeve
EP1502616A1 (de) 2003-08-01 2005-02-02 Bünder Glas GmbH Nadelschutz für eine Glasspritze
EP1502613A1 (en) 2003-08-01 2005-02-02 Novo Nordisk A/S Needle device with retraction means
CN1863566B (zh) 2003-08-12 2010-09-01 贝克顿·迪金森公司 片状输液装置
CA2534726C (en) 2003-08-12 2015-04-28 Becton, Dickinson And Company Patch-like infusion device
CN100531813C (zh) 2003-08-12 2009-08-26 伊莱利利公司 具有实现机械利益的三头螺纹的药物分配装置
US7097637B2 (en) 2003-08-27 2006-08-29 C. R. Bard, Inc. Safety needle with positive flush
AT7347U1 (de) 2003-08-29 2005-02-25 Pharma Consult Ges M B H & Co Vorrichtung zum automatischen injizieren von injektionsflüssigkeiten
IL157984A (en) 2003-09-17 2015-02-26 Dali Medical Devices Ltd Automatic needle
US7331942B2 (en) 2003-09-23 2008-02-19 Becton, Dickinson And Company Flush syringe having anti-reflux stopper
US7415525B2 (en) 2003-09-29 2008-08-19 Nokia Corporation USB application adopting bluetooth profile with a sharing implementation
US9033920B2 (en) 2003-10-02 2015-05-19 Medtronic, Inc. Determining catheter status
KR20060099520A (ko) 2003-10-21 2006-09-19 노보 노르디스크 에이/에스 의료용 피부 장착 장치
JP4658951B2 (ja) 2003-10-21 2011-03-23 ノボ・ノルデイスク・エー／エス 皮膚に装着可能な医療装置
SI2463201T1 (sl) 2003-10-30 2014-06-30 Teva Medical Ltd. Naprava za varno obdelavo zdravila
CA2545101A1 (en) 2003-11-06 2005-05-26 Misonix Incorporated Rf cauterization and ultrasonic ablation instrument with multi-hole collar and electrode mounting sleeve
US7850658B2 (en) 2003-11-10 2010-12-14 Smiths Medical Asd, Inc. Subcutaneous infusion device and method including release feature for adhesive portion
FR2876035B1 (fr) 2003-11-14 2007-03-30 Plastic Omnium Cie Ensemble de securite destine a equiper une seringue et ensemble de seringue
US7004104B1 (en) 2003-12-15 2006-02-28 Jerome Kundus Adjustable golf flagstick
CH696421A5 (de) 2003-12-18 2007-06-15 Tecpharma Licensing Ag Autoinjektor mit Arretierung des Wirkstoffbehälters.
US20050177136A1 (en) 2003-12-19 2005-08-11 Miller Landon C. Externally disposed pump for use with an internally mounted and compliant catheter
US20050154353A1 (en) 2004-01-09 2005-07-14 Alheidt Thomas A. Positive displacement flush syringe
WO2005070485A1 (en) 2004-01-09 2005-08-04 Becton, Dickinson And Company Positive displacement flush syringe
US20050159706A1 (en) 2004-01-20 2005-07-21 Becton, Dickinson And Company Medical syringe with safety shield system
WO2005072795A2 (en) 2004-01-29 2005-08-11 M 2 Medical A/S Disposable medicine dispensing device
CA2767913C (en) 2004-02-18 2014-04-15 Ares Trading S.A. Hand-held electronically controlled injection device for injecting liquid medications
JP4549079B2 (ja) 2004-03-05 2010-09-22 パナソニック株式会社 医療用投与器具
CN2689323Y (zh) 2004-03-11 2005-03-30 鸿富锦精密工业（深圳）有限公司 主板固定装置
US7699829B2 (en) 2004-03-25 2010-04-20 Boston Scientific Scimed, Inc. Catheter with sensor tip and method of use of same
US7565208B2 (en) 2004-03-25 2009-07-21 Boston Scientific Scimed, Inc. Catheter with sensor tips, tool and device and methods of use of same
US7585287B2 (en) 2004-06-16 2009-09-08 Smiths Medical Md, Inc. Device and method for insertion of a cannula of an infusion device
US7588559B2 (en) 2004-07-01 2009-09-15 W&H Dentalwerk Bürmoos GmbH Injection systems
US7255684B2 (en) 2004-08-09 2007-08-14 Boris Zubry Medical injection system
GB0418256D0 (en) 2004-08-16 2004-09-15 The Technology Partnership Plc Liquid dispensing device
WO2006032689A1 (en) 2004-09-22 2006-03-30 Novo Nordisk A/S Medical device with transcutaneous cannula device
EP1640029A1 (en) 2004-09-24 2006-03-29 Novo Nordisk A/S Injection device with cap
SI1799287T1 (sl) 2004-10-04 2013-10-30 Sanofi-Aventis Deutschland Gmbh Pogonski mehanizem za napravo za dovajanje zdravila
JP2008516709A (ja) 2004-10-21 2008-05-22 ノボ・ノルデイスク・エー／エス 放出された投薬量を示す信号の検出器を備えた薬剤送達システム
WO2006045525A1 (en) 2004-10-21 2006-05-04 Novo Nordisk A/S Injection device with a processor for collecting ejection information
US7255689B2 (en) 2004-10-29 2007-08-14 Safety Syringes, Inc. Syringe with anti-rotation for luer lock
EP1814616A1 (en) 2004-11-04 2007-08-08 Sid Technologies Llc Automatic injector
JP2006142369A (ja) 2004-11-24 2006-06-08 Ykk Corp 電動式射出ユニット及び同ユニットを備えたダイキャストマシンと電動式射出方法
EP3002019B1 (en) 2004-11-24 2021-06-09 SHL Medical AG Injection device
US7303543B1 (en) 2004-12-03 2007-12-04 Medtronic Minimed, Inc. Medication infusion set
USD544092S1 (en) 2004-12-03 2007-06-05 Kci Licensing, Inc. Wearable negative pressure wound care appliance
CN101484198A (zh) 2004-12-09 2009-07-15 韦斯特制药服务公司 尾部装有固定针的注射器和具有该注射器的自动注射装置
US7418880B1 (en) 2004-12-13 2008-09-02 Michael P Smith Sample collector using a syringe with a side port in the barrel
WO2006069380A1 (en) 2004-12-22 2006-06-29 Maili Corporation Device for administering an injection and method of using same
CN102895735B (zh) 2004-12-27 2015-12-16 皇家飞利浦电子股份有限公司 预置自动外部除纤颤器以便使用的方法
US9636450B2 (en) 2007-02-19 2017-05-02 Udo Hoss Pump system modular components for delivering medication and analyte sensing at seperate insertion sites
DE102004063664A1 (de) 2004-12-31 2006-07-20 Tecpharma Licensing Ag Echtzeitanzeige für eine Vorrichtung zur dosierten Verabreichung eines Produkts
US20060173439A1 (en) 2005-01-18 2006-08-03 Thorne Gale H Jr Syringe drive system
CN101107028B (zh) 2005-01-24 2013-04-10 诺和诺德公司 经皮设备组件
US7547281B2 (en) 2005-02-01 2009-06-16 Medtronic Minimed, Inc. Algorithm sensor augmented bolus estimator for semi-closed loop infusion system
US8231573B2 (en) 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
US7731686B2 (en) 2005-02-01 2010-06-08 Intelliject, Inc. Devices, systems and methods for medicament delivery
CA2762072C (en) 2005-02-01 2017-08-29 Intelliject, Inc. Devices, systems, and methods for medicament delivery
US7704229B2 (en) 2005-02-03 2010-04-27 Medtronic Minimed, Inc. Insertion device
CN101115516A (zh) 2005-02-21 2008-01-30 诺和诺德公司 确保注射设备中的电动机的恒速的方法
JP2008531093A (ja) 2005-02-23 2008-08-14 ノボ・ノルデイスク・エー／エス ピストンロッドを注入器具の中で反転させる方法及び装置
CA2601441A1 (en) 2005-03-21 2006-09-28 Abbott Diabetes Care Inc. Method and system for providing integrated medication infusion and analyte monitoring system
WO2006102676A1 (en) 2005-03-23 2006-09-28 Tissue Engineering Refraction, Inc. Injectable polyethylene oxide dermal fillers and related devices
ATE413895T1 (de) 2005-03-24 2008-11-15 Disetronic Licensing Ag Vorrichtung für die dosierte verabreichung eines fluiden produkts
EP1874390B1 (en) 2005-03-28 2014-10-01 Insulet Corporation Fluid delivery device
JP2008534131A (ja) 2005-03-28 2008-08-28 インシュレット コーポレイション 流体投与装置
EP1877115A1 (en) 2005-04-06 2008-01-16 M 2 Medical A/S An actuator
WO2006111862A1 (en) 2005-04-20 2006-10-26 Becton Dickinson France Injection set and injection assistance device
US7686787B2 (en) 2005-05-06 2010-03-30 Medtronic Minimed, Inc. Infusion device and method with disposable portion
US8277415B2 (en) 2006-08-23 2012-10-02 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US7905868B2 (en) 2006-08-23 2011-03-15 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
EP1898975A2 (en) 2005-05-13 2008-03-19 Novo Nordisk A/S Medical device adapted to detect disengagement of a transcutaneous device
US8021357B2 (en) 2005-05-27 2011-09-20 Olympus Corporation Body-insertable apparatus
DE102005025639B4 (de) 2005-06-03 2011-04-07 Innovacell Biotechnologie Gmbh Injektionsvorrichtung
US20060283465A1 (en) 2005-06-16 2006-12-21 Nickel Janice H Smart drug delivery system and a method of implementation thereof
EP1904130B1 (en) 2005-06-21 2016-03-30 Eli Lilly And Company Needled pharmaceutical delivery device with triggered automatic needle insertion and manually controlled pharmaceutical injection
US20070025879A1 (en) 2005-07-27 2007-02-01 Dakocytomation Denmark A/S Method and apparatus for syringe-based sample introduction within a flow cytometer
EP1909870B2 (en) 2005-07-27 2016-01-20 Novo Nordisk A/S Dose mechanism for an injection device for limiting a dose setting corresponding to the amount of medicament left
US7713240B2 (en) 2005-09-13 2010-05-11 Medtronic Minimed, Inc. Modular external infusion device
US8105279B2 (en) 2005-09-26 2012-01-31 M2 Group Holdings, Inc. Dispensing fluid from an infusion pump system
US8057436B2 (en) 2005-09-26 2011-11-15 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
EP1933901B1 (en) 2005-09-26 2014-12-31 Asante Solutions, Inc. Portable infusion pump having a flexible pushrod with hinged portions
US8409142B2 (en) 2005-09-26 2013-04-02 Asante Solutions, Inc. Operating an infusion pump system
US7534226B2 (en) 2005-09-26 2009-05-19 M2 Group Holdings, Inc. Dispensing fluid from an infusion pump system
US8551046B2 (en) 2006-09-18 2013-10-08 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
WO2007050528A1 (en) 2005-10-25 2007-05-03 Bayer Healthcare Llc Single use lancing device
ATE541600T1 (de) 2005-11-02 2012-02-15 Injectica Ag Implantierbares infusionsgerät mit ausfahrbarer und einziehbarer nadel
US7935104B2 (en) 2005-11-07 2011-05-03 Medingo, Ltd. Systems and methods for sustained medical infusion and devices related thereto
ATE439155T1 (de) 2005-11-08 2009-08-15 M2 Medical As Infusionspumpensystem
GB2433032A (en) 2005-12-08 2007-06-13 Owen Mumford Ltd Syringe with dose adjustment means
JP4358821B2 (ja) 2005-12-15 2009-11-04 オリンパス株式会社 被検体内導入装置
EP1963981B1 (en) 2005-12-20 2011-10-26 Siemens Aktiengesellschaft Backplane for a programmable logic controller
US7988660B2 (en) 2005-12-20 2011-08-02 Eli Lilly And Company Needle-free injection device
ES2327963T3 (es) 2005-12-23 2009-11-05 Unomedical A/S Dispositivo de inyeccion.
US7549976B2 (en) 2005-12-28 2009-06-23 Smiths Medical Md, Inc. Portal access device with removable sharps protection
GB0600351D0 (en) 2006-01-10 2006-02-15 Weston Terence E Safe hypodermic needle
WO2007119178A2 (en) 2006-01-23 2007-10-25 Neuren Pharmaceuticals Limited Infusion pump
US7780635B2 (en) 2006-02-09 2010-08-24 Aderans Research Institute, Inc. Apparatus and methods for delivering fluid and material to a subject
USD578210S1 (en) 2006-03-14 2008-10-07 Hisamitsu Pharmaceutical Co., Inc. Injector
US8114064B2 (en) 2006-03-16 2012-02-14 Calibra Medical, Inc. Infusion device with piston pump
DE102006013322A1 (de) 2006-03-21 2007-09-27 Sarstedt Ag & Co. Kanüle mit einem Schutzgehäuse
GB2436526B (en) 2006-03-29 2010-01-27 Arash Bakhtyari-Nejad-Esfahani Syringe
US9392969B2 (en) 2008-08-31 2016-07-19 Abbott Diabetes Care Inc. Closed loop control and signal attenuation detection
AT502791B1 (de) 2006-04-06 2007-05-15 Pharma Consult Ges M B H & Co Injektionsspritze
WO2007118908A1 (en) 2006-04-19 2007-10-25 Novo Nordisk A/S A fluid infusion system, a method of assembling such system and drug reservoir for use in the system
JP4982722B2 (ja) 2006-04-19 2012-07-25 ノボ・ノルデイスク・エー／エス 流体注入システム、同システムの組み立て方法、及び同システムに使用される薬剤容器
TWI298216B (en) 2006-04-21 2008-06-21 Hon Hai Prec Ind Co Ltd Power supply devices and electronic products using the same
US7589974B2 (en) 2006-04-21 2009-09-15 Helwett-Packard Development Company, L.P. Modular server and method
MX2008013742A (es) * 2006-04-28 2008-11-14 Nipro Corp Ensamble de aguja de seguridad.
FR2900749B1 (fr) 2006-05-05 2008-07-25 Thales Sa Procede et dispositif de securisation de la memoire d'un calculateur a l'encontre des erreurs dues aux radiations
JP4833731B2 (ja) * 2006-05-16 2011-12-07 テルモ株式会社 シリンジポンプ
AU2007253481B2 (en) 2006-05-18 2013-01-17 Novo Nordisk A/S An injection device with mode locking means
US20070282269A1 (en) 2006-05-31 2007-12-06 Seattle Medical Technologies Cannula delivery apparatus and method for a disposable infusion device
WO2008001378A2 (en) 2006-06-28 2008-01-03 Perf-Action Technologies Ltd Intradermal needle-less injection device
BRPI0713802A2 (pt) 2006-06-30 2012-11-06 Abbott Biotech Ltd dispositivo de injeção automático
US7666165B2 (en) 2006-07-06 2010-02-23 Warsaw Orthopedic, Inc. Cannulated sensing device
JP4738275B2 (ja) 2006-07-07 2011-08-03 日本航空電子工業株式会社 ランプ管用コネクタ
US8382718B2 (en) 2006-07-31 2013-02-26 B. Braun Melsungen Ag Needle assembly and components thereof
US7740792B2 (en) 2006-08-03 2010-06-22 Medrad, Inc. Methods of molding a syringe
GB0615589D0 (en) 2006-08-04 2006-09-13 Salvus Technology Ltd Safety needle accessory
US8206296B2 (en) 2006-08-07 2012-06-26 Abbott Diabetes Care Inc. Method and system for providing integrated analyte monitoring and infusion system therapy management
US7789857B2 (en) 2006-08-23 2010-09-07 Medtronic Minimed, Inc. Infusion medium delivery system, device and method with needle inserter and needle inserter device and method
CA2662223A1 (en) 2006-08-28 2008-03-06 Akimichi Oda Plant component-containing polycarbonate resin composition
DE602007011637D1 (de) 2006-08-28 2011-02-10 Novo Nordisk As Axial verschliessbares und durch drehung zu öffnendes medikamentenverabreichungssystem
CN100596233C (zh) 2006-08-31 2010-03-24 华为技术有限公司 移动通信切换方法及其系统和基站
US20080097387A1 (en) 2006-09-04 2008-04-24 Spector David M Oral cavity liquid delivery system including pre-angled needle assembly and method for using the same
FR2905273B1 (fr) 2006-09-06 2009-04-03 Becton Dickinson France Soc Pa Dispositif d'injection automatique avec moyen de temporisation.
US8162923B2 (en) 2006-09-06 2012-04-24 Calibra Medical, Inc. Disposable infusion device with automatic unlocking mechanism
DE102006049528A1 (de) 2006-09-28 2008-04-03 Robert Bosch Gmbh Vorrichtung und Verfahren zur Montage eines Nadelschutzes auf einen Spritzenkörper
DE102006047537B4 (de) 2006-10-07 2024-05-16 Sanofi-Aventis Deutschland Gmbh Verfahren und Vorrichtung zur Bestimmung der Position eines Stopfens einer Ampulle für ein Arzneimittel in einem medizinischen Gerät sowie deren Verwendung, ein entsprechendes medizinisches Gerät sowie Herstellung eines medizinischen Geräts
WO2008043724A2 (en) 2006-10-12 2008-04-17 Dynamic Therapeutics Ltd Regulated drug delivery system
US8974410B2 (en) 2006-10-30 2015-03-10 Vidacare LLC Apparatus and methods to communicate fluids and/or support intraosseous devices
WO2008057976A2 (en) 2006-11-03 2008-05-15 Avanca Medical Devices, Inc. Multiple dose syringes
US7780637B2 (en) 2006-11-06 2010-08-24 Steven Jerde Medical device container
GB2443606B (en) 2006-11-13 2011-07-20 Cilag Gmbh Int Injection device
EP1923083A1 (en) 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Drive mechanisms for use in drug delivery devices
US7704227B2 (en) 2006-11-29 2010-04-27 Medtronic Minimed, Inc. Methods and apparatuses for detecting medical device acceleration, temperature, and humidity conditions
WO2008073214A2 (en) 2006-12-08 2008-06-19 Boston Scientific Limited Therapeutic catheter with displacement sensing transducer
WO2008072229A2 (en) 2006-12-12 2008-06-19 Nanopass Technologies Ltd. Methods for dermal filling using microneedles
ATE514443T1 (de) 2006-12-13 2011-07-15 Shl Group Ab Autoinjektor
US8057431B2 (en) 2006-12-21 2011-11-15 B. Braun Melsungen Ag Hinged cap for needle device
DK3632488T3 (da) 2006-12-22 2023-06-06 Hoffmann La Roche Anordning til vedvarende indgivelse af en terapeutisk væske
US7488181B2 (en) 2007-01-09 2009-02-10 Laird Technologies, Inc. Electrocoated contacts compatible with surface mount technology
US9283177B2 (en) 2007-01-16 2016-03-15 Juventio, Llc Topical anesthetic for rapid local anesthesia and method of applying a topical anesthetic
US7540858B2 (en) 2007-01-23 2009-06-02 Becton, Dickinson And Company Retracting safety pen needle
US8038654B2 (en) 2007-02-26 2011-10-18 Becton, Dickinson And Company Syringe having a hinged needle shield
FR2913202A1 (fr) 2007-03-02 2008-09-05 Becton Dickinson France Soc Pa Protection pour couvrir l'extremite d'un dispositif d'administration ou d'un sous-ensemble,sous-ensemble et dispositif d'administration
DK1970084T3 (da) 2007-03-14 2010-11-22 Hoffmann La Roche Indføringsapparat til en indføringshoved, især til et infusionssæt
DE102007013838A1 (de) 2007-03-22 2008-09-25 Tecpharma Licensing Ag Injektionsvorrichtung mit zeitkonstantem Ausschüttsignal
AU2008231897B2 (en) 2007-03-23 2012-11-29 Novo Nordisk A/S An injection device comprising a locking nut
EP1974759A1 (de) 2007-03-29 2008-10-01 Jürgen Schmidt-Evers Injektionsgerät, insbesondere Insulin-Pen
US8034019B2 (en) 2007-04-10 2011-10-11 Amrita Vishwa Vidyapeetham Dual microcontroller-based liquid infusion system
US7501587B2 (en) 2007-04-16 2009-03-10 Laird Technologies, Inc. Mounting clips for use with electromagnetic interference shielding and methods of using the same
US8556861B2 (en) 2007-04-23 2013-10-15 Sid Technologies, Llc Methods and devices for intradermal injection
US20080269723A1 (en) 2007-04-25 2008-10-30 Medtronic Minimed, Inc. Closed loop/semi-closed loop therapy modification system
JP4867775B2 (ja) 2007-04-26 2012-02-01 株式会社ジェイ・エム・エス 注射器ホルダ及び注射器装置
FI7960U1 (fi) 2007-04-27 2008-07-28 Bayer Schering Pharma Oy Implantoitavan annostelusysteemin membraanikuori
US7963954B2 (en) 2007-04-30 2011-06-21 Medtronic Minimed, Inc. Automated filling systems and methods
US8323250B2 (en) 2007-04-30 2012-12-04 Medtronic Minimed, Inc. Adhesive patch systems and methods
DK2146760T3 (en) 2007-04-30 2019-01-28 Medtronic Minimed Inc FILLING OF RESERVOIR, BUBBLE MANAGEMENT AND DELIVERY SYSTEMS FOR INFUSION MEDIA AND PROCEDURES
WO2008137766A2 (en) 2007-05-02 2008-11-13 Wireless Control Network Solutions, Llc Systems and methods for dynamically configuring node behavior in a sensor network
MX2009011953A (es) 2007-05-07 2010-03-29 Unomedical As Canula y dispositivo de suministro.
US9173993B2 (en) 2007-05-11 2015-11-03 Roche Diabetes Care, Inc. Fluid delivery device
US7794426B2 (en) 2007-05-21 2010-09-14 Asante Solutions, Inc. Infusion pump system with contamination-resistant features
CA125684S (en) 2007-05-31 2008-06-26 Danfoss Bionics As Insulin pump
US8157693B2 (en) 2007-06-19 2012-04-17 American Axle & Manufacturing, Inc. Helical differential assembly with preloaded adjustment mechanism
US8002752B2 (en) 2007-06-25 2011-08-23 Medingo, Ltd. Protector apparatus
DK2173407T3 (da) 2007-07-02 2020-04-27 Hoffmann La Roche Anordning til indgivelse af lægemiddel
EP2183006B1 (en) 2007-07-20 2019-02-13 Roche Diabetes Care GmbH Manually operable portable infusion device
DK2185218T3 (da) 2007-08-01 2013-09-30 Medingo Ltd Aftagelig bærbar infusionsanordning
GB2451666B (en) 2007-08-08 2012-08-22 Cilag Gmbh Int Injection device
GB2452030A (en) * 2007-08-10 2009-02-25 Owen Mumford Ltd Injection devices
US7828528B2 (en) 2007-09-06 2010-11-09 Asante Solutions, Inc. Occlusion sensing system for infusion pumps
US7717903B2 (en) 2007-09-06 2010-05-18 M2 Group Holdings, Inc. Operating an infusion pump system
US8032226B2 (en) 2007-09-07 2011-10-04 Asante Solutions, Inc. User profile backup system for an infusion pump device
US7879026B2 (en) 2007-09-07 2011-02-01 Asante Solutions, Inc. Controlled adjustment of medicine dispensation from an infusion pump device
ES2742504T3 (es) * 2007-09-25 2020-02-14 Becton Dickinson France Autoinyector con elemento de eliminación de blindaje que comprende medios antimanipulación
CN101868275B (zh) 2007-09-25 2012-12-12 贝克顿迪金森法国公司 自我注射器
US8469923B2 (en) 2007-09-27 2013-06-25 Becton, Dickinson And Company Cartridge for powder and liquid drug
US7771391B2 (en) 2007-09-28 2010-08-10 Calibra Medical, Inc. Disposable infusion device with snap action actuation
US8128596B2 (en) 2007-09-28 2012-03-06 Calibra Medial, Inc. Disposable infusion device layered structure
WO2009043564A1 (en) 2007-10-01 2009-04-09 Roche Diagnostics Gmbh Cartridge adapter for use in an infusion system
US7967795B1 (en) 2010-01-19 2011-06-28 Lamodel Ltd. Cartridge interface assembly with driving plunger
US10420880B2 (en) 2007-10-02 2019-09-24 West Pharma. Services IL, Ltd. Key for securing components of a drug delivery system during assembly and/or transport and methods of using same
US9656019B2 (en) 2007-10-02 2017-05-23 Medimop Medical Projects Ltd. Apparatuses for securing components of a drug delivery system during transport and methods of using same
US9345836B2 (en) 2007-10-02 2016-05-24 Medimop Medical Projects Ltd. Disengagement resistant telescoping assembly and unidirectional method of assembly for such
CN101868273B (zh) 2007-10-02 2014-10-15 莱蒙德尔有限公司 外部药泵
FR2922112B1 (fr) 2007-10-11 2009-12-04 Rexam Pharma La Verpilliere Dispositif de securite pour une seringue d'injection de liquide et ensemble a seringue comprenant ce dispositif
DK2195048T3 (en) 2007-10-11 2019-03-11 Hoffmann La Roche CARRIER FOR AN INFUSION SYSTEM
DE102007049446A1 (de) 2007-10-16 2009-04-23 Cequr Aps Katheter-Einführeinrichtung
US7922695B2 (en) 2007-10-18 2011-04-12 Roche Diagnostics Operations, Inc. Drug delivery pump drive using linear piezoelectric motor
EP2052677A1 (en) 2007-10-23 2009-04-29 Sensile Pat AG Medical device for glucose monitoring or regulation
JP5215632B2 (ja) 2007-10-25 2013-06-19 テルモ株式会社 コネクタのプライミング方法
ES2668367T3 (es) 2007-11-12 2018-05-17 Medicom Innovation Partner A/S Autoinyector con vástago de liberación giratorio
US8308695B2 (en) 2007-11-14 2012-11-13 Shl Group Ab Automatic injection device with actively triggered syringe withdrawal
JP2009119171A (ja) 2007-11-19 2009-06-04 Daikyo Seiko Ltd プランジャロッドおよび注射器
GB2446247B (en) 2007-11-27 2008-12-17 Robert Joseph Wagener Homeostatic insulin pump
WO2009069064A1 (en) 2007-11-27 2009-06-04 Koninklijke Philips Electronics N.V. Implantable therapeutic substance delivery device
US7918825B2 (en) 2007-11-29 2011-04-05 Insulet Corporation Interfacing a prefilled syringe with an infusion pump to fill the infusion pump
US7771392B2 (en) 2007-11-29 2010-08-10 Roche Diagnostics Operations, Inc. Lead screw delivery device using reusable shape memory actuator drive
US7806868B2 (en) 2007-11-30 2010-10-05 Roche Diagnostics Operations, Inc. Drug reservoir loading and unloading mechanism for a drug delivery device using a unidirectional rotated shaft
US20090149830A1 (en) 2007-12-07 2009-06-11 Donald Spector Intelligent needle technology for acupuncture and injection of cosmetic preparations subcutaneously
CN101461976A (zh) 2007-12-21 2009-06-24 关和瑜 一种笔式胰岛素注射器常规胰岛素专用笔芯
US20100280499A1 (en) 2007-12-26 2010-11-04 Ofer Yodfat System and method for glycemic control
US8313467B2 (en) 2007-12-27 2012-11-20 Medtronic Minimed, Inc. Reservoir pressure equalization systems and methods
EP2240222B1 (en) * 2008-01-11 2018-04-04 UCB Biopharma SPRL Systems for administering medication for rheumatoid arthritis patients
US8721603B2 (en) 2008-01-15 2014-05-13 West Pharmaceutical Services, Inc. Syringe with co-molded hub and cannula
CN101896214B (zh) 2008-01-15 2013-05-29 西部制药服务公司 将插管模制到注射器针筒上的筒夹机构和方法
US8708961B2 (en) 2008-01-28 2014-04-29 Medsolve Technologies, Inc. Apparatus for infusing liquid to a body
USD604835S1 (en) 2008-02-01 2009-11-24 Conley N Sharon Patient controlled timed medication dispenser
GB0802351D0 (en) 2008-02-08 2008-03-12 Owen Mumford Ltd Injection devices
US20090209896A1 (en) 2008-02-19 2009-08-20 Selevan James R Method and apparatus for time-dependent and temperature-dependent clinical alert
US9446185B2 (en) 2008-03-12 2016-09-20 Roche Diabetes Care, Inc. Devices and methods for improving accuracy of fluid delivery
US8540673B2 (en) 2008-03-18 2013-09-24 Calibra Medical, Inc. Disposable infusion device with actuation lock-out
DK2260423T3 (en) 2008-04-04 2018-06-06 Hygieia Inc DEVICE FOR OPTIMIZING A PATIENT'S INSULIN DOSAGE PLAN
US20090259176A1 (en) 2008-04-09 2009-10-15 Los Gatos Research, Inc. Transdermal patch system
ES2772756T3 (es) 2008-04-09 2020-07-08 Hoffmann La Roche Sensor de nivel de líquido para un sistema modular adherente a la piel para la administración médica de líquidos
US8287520B2 (en) 2008-04-10 2012-10-16 Medtronic, Inc. Automated integrity tests
CN101977645B (zh) 2008-04-10 2013-01-30 松下电器产业株式会社 给药装置
ES2403057T3 (es) 2008-04-18 2013-05-13 Kuros Biosurgery Ag Dispositivo de suministro, kit que contiene el dispositivo, y método para operar el dispositivo
JP5227645B2 (ja) 2008-04-21 2013-07-03 矢崎総業株式会社 基板用コネクタ
ATE538825T1 (de) 2008-05-07 2012-01-15 Hoffmann La Roche Anzeige für ein infusionsabgabesystem
CA3070644C (en) 2008-05-20 2022-09-13 Avant Medical Corp. Autoinjector system
US8177749B2 (en) 2008-05-20 2012-05-15 Avant Medical Corp. Cassette for a hidden injection needle
US8231577B2 (en) * 2008-06-26 2012-07-31 Calibra Medical, Inc. Disposable infusion device with automatically releasable cannula driver
ATE510575T1 (de) 2008-06-30 2011-06-15 Animas Corp Antriebsmechanismus
US20090326509A1 (en) 2008-06-30 2009-12-31 Muse Philip A Context aware medical monitoring and dosage delivery device
WO2010003885A1 (en) 2008-07-07 2010-01-14 Unomedical A/S Inserter for transcutaneous device
US9155842B2 (en) 2008-07-09 2015-10-13 Sanofi-Aventis Deutschland Gmbh Medication delivery device and method of assembling a medication delivery device
DE102008033887B4 (de) 2008-07-18 2012-02-09 weiss Präzisionstechnik GmbH & Co. KG Teleskop-Doppelspindelantrieb
US8706863B2 (en) 2008-07-18 2014-04-22 Apple Inc. Systems and methods for monitoring data and bandwidth usage
USD602586S1 (en) 2008-07-23 2009-10-20 Animas Corporation Drug delivery pod
USD602155S1 (en) 2008-07-28 2009-10-13 Animas Corporation Drug delivery pod
US8795259B2 (en) 2008-08-01 2014-08-05 Wisconsin Alumni Research Foundation Drug delivery platform incorporating hydrogel pumping mechanism with guided fluid flow
US8986250B2 (en) 2008-08-01 2015-03-24 Wisconsin Alumni Research Foundation Drug delivery platform utilizing hydrogel pumping mechanism
KR101013581B1 (ko) 2008-08-06 2011-02-14 라종주 전기 피부 미용기
DE102008037310B4 (de) 2008-08-11 2023-11-16 Ypsomed Ag Automatische Injektionsvorrichtung für die Verabreichung einer festen Dosis
GB0814747D0 (en) 2008-08-13 2008-09-17 Owen Mumford Ltd Autoinjection devices
US8029526B2 (en) 2008-08-14 2011-10-04 Abbott Diabetes Care Inc. Cocking mechanism for lancing device
EP2326365B1 (en) 2008-08-18 2020-01-01 Calibra Medical LLC Drug infusion system with reusable and disposable components
GB0815897D0 (en) 2008-09-01 2008-10-08 Benmore Ventures Ltd Container illumination device
US20110224646A1 (en) 2008-09-11 2011-09-15 Ofer Yodfat Methods and Devices for Tailoring a Bolus Delivery Pattern
WO2010030965A2 (en) 2008-09-15 2010-03-18 Klein, David Painless injector
US9427529B2 (en) 2008-09-15 2016-08-30 Medimop Medical Projects Ltd. Safeguard mechanism for autoinjector needle
US9393369B2 (en) 2008-09-15 2016-07-19 Medimop Medical Projects Ltd. Stabilized pen injector
ES2657674T3 (es) 2008-09-29 2018-03-06 Becton Dickinson France Dispositivo de inyección con medios de retención accionados por protector de aguja
CN102209564B (zh) 2008-09-29 2014-06-25 贝克顿迪金森法国公司 带有完成输送声响指示的注射装置
PT2346552E (pt) 2008-10-13 2012-11-06 Sanofi Aventis Deutschland Dispositivo de administração de fármaco e método de fabricar um dispositivo de administração de fármaco
US20100145305A1 (en) 2008-11-10 2010-06-10 Ruth Alon Low volume accurate injector
EP2355944A1 (en) * 2008-11-11 2011-08-17 Novo Nordisk A/S A bended injection needle
WO2010059415A2 (en) 2008-11-18 2010-05-27 B. Braun Melsungen Ag Protective shield for a hypodermic syringe
EP2198904A1 (en) 2008-12-19 2010-06-23 Sanofi-Aventis Deutschland GmbH Interlock mechanism for a drug delivery device and drug delivery device
EP2201968A1 (de) 2008-12-24 2010-06-30 Roche Diagnostics GmbH Insertionssystem und Insertionsvorrichtung
US8152779B2 (en) 2008-12-30 2012-04-10 Medimop Medical Projects Ltd. Needle assembly for drug pump
DK2391408T3 (en) 2008-12-31 2018-02-05 Hoffmann La Roche PORTABLE MEDICAL FLUID ADMINISTRATION WITH DRIVE SCREW LED CONNECTOR WITH CONTAINER STAMP
DK2379104T3 (en) 2008-12-31 2018-04-30 Revance Therapeutics Inc Injectable botulinum toxin formulations
US8790295B1 (en) 2009-01-05 2014-07-29 Medtronic, Inc. Pressure monitoring to control delivery of therapeutic agent
KR20100086881A (ko) 2009-01-23 2010-08-02 삼성전자주식회사 백라이트 어셈블리 및 이를 포함하는 표시 장치
US8221352B2 (en) 2009-01-29 2012-07-17 Michael Merchant Disposable safety needle system and safety enclosure means
CN102378638A (zh) 2009-02-05 2012-03-14 赛诺菲-安万特德国有限公司 药物递送设备
TWI519331B (zh) 2009-02-05 2016-02-01 賽諾菲阿凡提斯德意志有限公司 藥物傳輸裝置（二）
BRPI1007907A2 (pt) 2009-02-05 2016-02-16 Sanofi Aventis Deutschland dispositivos de envio de medicamento
JP5667160B2 (ja) 2009-03-31 2015-02-12 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬剤送達デバイスにおける及び薬剤送達デバイスに関する改良
EP2241344B1 (en) 2009-04-16 2013-12-11 F. Hoffmann-La Roche AG Ambulatory infusion device with sensor testing unit
AU2010251140B2 (en) 2009-05-20 2015-01-29 Sanofi-Aventis Deutschland Gmbh A bung for drug containing cartridges in drug delivery devices
EP2440267B1 (de) * 2009-06-10 2018-10-24 Fresenius Kabi Deutschland GmbH Portkanüle mit nadelstichschutzvorrichtung
CN102481415B (zh) 2009-07-08 2014-03-05 诺沃—诺迪斯克有限公司 防冻注射设备
WO2011006925A1 (en) 2009-07-15 2011-01-20 Sanofi-Aventis Deutschland Gmbh Drive mechanism for an injection device and an injection device with such a drive mechanism
WO2011010466A1 (ja) 2009-07-23 2011-01-27 パナソニック株式会社 シリンジ駆動装置及び調剤装置
WO2011011697A1 (en) 2009-07-23 2011-01-27 Sid Technologies, Llc Intradermal injection adapter
CN102497909B (zh) 2009-07-31 2014-10-29 3M创新有限公司 中空微针阵列
US20120193256A1 (en) 2009-08-07 2012-08-02 Becton Dickinson France Tray for positioning elongated objects, in particular syringe bodies or syringes
CN102574123B (zh) * 2009-08-10 2015-02-11 西部制药服务公司 用于填装无凸缘容器的装置和方法
US8547239B2 (en) 2009-08-18 2013-10-01 Cequr Sa Methods for detecting failure states in a medicine delivery device
US8308679B2 (en) 2009-12-30 2012-11-13 Medtronic Minimed, Inc. Alignment systems and methods
US8900190B2 (en) 2009-09-02 2014-12-02 Medtronic Minimed, Inc. Insertion device systems and methods
US10071196B2 (en) 2012-05-15 2018-09-11 West Pharma. Services IL, Ltd. Method for selectively powering a battery-operated drug-delivery device and device therefor
US8157769B2 (en) 2009-09-15 2012-04-17 Medimop Medical Projects Ltd. Cartridge insertion assembly for drug delivery system
CA2772494A1 (en) 2009-09-18 2011-03-24 Sanofi-Aventis Deutschland Gmbh Arrangement for determining a longitudinal position of a stopper
EP2484393B1 (en) 2009-09-30 2014-07-30 Terumo Kabushiki Kaisha Pre-filled syringe
WO2011043714A1 (en) 2009-10-08 2011-04-14 Shl Group Ab Medicament delivery device
US8808248B2 (en) 2009-10-15 2014-08-19 Biosense Webster, Inc. Catheter sheath introducer with rotational lock
EP2488237B1 (en) 2009-10-16 2018-07-04 Janssen Biotech, Inc. Palm activated drug delivery device
JP2011136151A (ja) 2009-10-19 2011-07-14 Terumo Medical Corp 着脱可能な注射針組立体及び低デッドスペースを有している注射器組立体
EP3366337B1 (en) 2009-10-21 2019-12-04 Owen Mumford Limited Autoinjector
JP5408541B2 (ja) 2009-11-06 2014-02-05 北川工業株式会社 表面実装クリップ
US8241240B2 (en) 2009-11-09 2012-08-14 Medtronic Xomed, Inc. Adjustable valve setting with motor control
DK2327433T3 (da) 2009-11-26 2012-07-23 Hoffmann La Roche Udefra udløselig kanyleanordning
CN102753234A (zh) 2009-12-16 2012-10-24 贝克顿·迪金森公司 自注射装置
US8795260B2 (en) 2009-12-18 2014-08-05 Medtronic, Inc. Refill of implantable fluid delivery devices based on therapeutic fluid expiration
US8858500B2 (en) 2009-12-30 2014-10-14 Medtronic Minimed, Inc. Engagement and sensing systems and methods
US8435209B2 (en) 2009-12-30 2013-05-07 Medtronic Minimed, Inc. Connection and alignment detection systems and methods
US20110172645A1 (en) 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US8348898B2 (en) 2010-01-19 2013-01-08 Medimop Medical Projects Ltd. Automatic needle for drug pump
US9295778B2 (en) 2011-12-21 2016-03-29 Deka Products Limited Partnership Syringe pump
US9789247B2 (en) 2011-12-21 2017-10-17 Deka Products Limited Partnership Syringe pump, and related method and system
EP2525851B1 (en) 2010-01-22 2019-05-08 Sanofi-Aventis Deutschland GmbH Coded cartridge holder and fastener enabled by cartridge size
USD650079S1 (en) 2010-02-08 2011-12-06 Abbott Diabetes Care Inc. Analyte meter
CA2789561A1 (en) 2010-02-18 2011-08-25 Sanofi-Aventis Deutschland Gmbh Finger guard for an injection device
DK2536452T3 (da) 2010-02-18 2019-01-02 Sanofi Aventis Deutschland Autoinjektor
CA2790188A1 (en) 2010-02-18 2011-08-25 Sanofi-Aventis Deutschland Gmbh Auto-injector
EP2361648A1 (en) 2010-02-18 2011-08-31 Sanofi-Aventis Deutschland GmbH Remover for a protective needle shield
WO2011101382A1 (en) 2010-02-22 2011-08-25 Sanofi-Aventis Deutschland Gmbh Auto - injector with needle shroud and needle protection cap
CA2790283A1 (en) 2010-02-22 2011-08-25 Sanofi-Aventis Deutschland Gmbh Force transmission arrangement for auto-injector
EP2364739A1 (en) 2010-03-09 2011-09-14 Sanofi-Aventis Deutschland GmbH Re-usable autoinjector
EP2544741B1 (en) 2010-03-09 2016-05-11 SHL Group AB Medicament delivery device
JPWO2011111321A1 (ja) 2010-03-11 2013-06-27 パナソニック株式会社 音声読み上げ装置および音声読み上げ方法
GB201004102D0 (en) 2010-03-12 2010-04-28 Liversidge Barry P Syringe barrels and handling systems
US8674288B2 (en) 2010-03-24 2014-03-18 Medtronic Minimed, Inc. Motor assembly sensor capture systems and methods
USD652503S1 (en) 2010-04-08 2012-01-17 Cequr Sa Medical device
JP5956978B2 (ja) 2010-04-09 2016-07-27 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬物リザーバの屈曲可能ロッキングエレメントを備えたコード化された連結エレメント
JP5878115B2 (ja) * 2010-04-16 2016-03-08 株式会社根本杏林堂 シリンジ保持構造
US8810394B2 (en) 2010-04-16 2014-08-19 Medtronic, Inc. Reservoir monitoring for implantable fluid delivery devices
CN201692438U (zh) 2010-04-20 2011-01-05 深圳市利泰尔科技有限公司 配置自动给药传动组件的胰岛素泵
US9180244B2 (en) 2010-04-21 2015-11-10 Abbvie Biotechnology Ltd Wearable automatic injection device for controlled delivery of therapeutic agents
EP2560706B1 (en) 2010-04-23 2019-11-27 Sanofi-Aventis Deutschland GmbH Cartridge holder and alignment interface
WO2011131781A1 (en) 2010-04-23 2011-10-27 Sanofi-Aventis Deutschland Gmbh Coded keying insert for a medicament cartridge
CN102946927B (zh) 2010-04-23 2015-01-21 赛诺菲-安万特德国有限公司 标记的药筒组件
CA2796742A1 (en) 2010-04-23 2011-10-27 Sanofi-Aventis Deutschland Gmbh Coded ferrule for a drug delivery device
US8246573B2 (en) 2010-04-27 2012-08-21 Medtronic, Inc. Detecting empty medical pump reservoir
WO2011141907A1 (en) 2010-05-10 2011-11-17 Medimop Medical Projects Ltd. Low volume accurate injector
CA2799721C (en) 2010-05-20 2016-09-06 Becton, Dickinson And Company Drug delivery device
KR102513760B1 (ko) 2010-06-07 2023-03-27 암젠 인크 약물 전달 장치
WO2011154355A1 (en) 2010-06-07 2011-12-15 Sanofi-Aventis Deutschland Gmbh Drug delivery device with light source
TW201212959A (en) 2010-06-22 2012-04-01 Thoratec Corp Fluid delivery system and method for monitoring fluid delivery system
EP2399628A1 (en) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2399631A1 (en) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector with injection damper
EP2399633A1 (en) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Needle safety arrangement and method for operating it
EP2399627A1 (en) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
US9427531B2 (en) 2010-06-28 2016-08-30 Sanofi-Aventis Deutschland Gmbh Auto-injector
CN103037982A (zh) 2010-06-29 2013-04-10 Csp技术公司 具有集成针头的注射器
US20110319861A1 (en) 2010-06-29 2011-12-29 Robert Wilk Medical device mechanical pump
US8172591B2 (en) 2010-07-05 2012-05-08 Hon Hai Precision Ind. Co., Ltd. Electrical connector assembly having electrical connector with low profile and processor with cone pins
USD650903S1 (en) 2010-07-09 2011-12-20 Becton, Dickinson And Company Syringe barrel
JP2013530778A (ja) 2010-07-13 2013-08-01 ノボ・ノルデイスク・エー／エス ピストンロッドフット
US9675751B2 (en) 2010-07-31 2017-06-13 Becton, Dickinson And Company Infusion reservoir with push-on connector features and/or attachments therefor
US20130204187A1 (en) 2010-08-06 2013-08-08 Sanofi-Aventis Deutschland Gmbh Method and system for retaining a cartridge in a holder
US8512295B2 (en) 2010-08-19 2013-08-20 West Pharmaceutical Services, Inc. Rigid needle shield
US8764962B2 (en) 2010-08-23 2014-07-01 Massachusetts Institute Of Technology Extraction of liquid elements by electrolysis of oxides
WO2012032411A2 (en) 2010-09-07 2012-03-15 Tecpharma Licensing Ag Automatic injection device
US9320849B2 (en) 2010-09-24 2016-04-26 Perqflo, Llc Infusion pumps
US9421337B2 (en) 2010-10-08 2016-08-23 Sanofi-Aventis Deutschland Gmbh Auto-injector
US8474332B2 (en) 2010-10-20 2013-07-02 Medtronic Minimed, Inc. Sensor assembly and medical device incorporating same
US8495918B2 (en) 2010-10-20 2013-07-30 Medtronic Minimed, Inc. Sensor assembly and medical device incorporating same
US8479595B2 (en) 2010-10-20 2013-07-09 Medtronic Minimed, Inc. Sensor assembly and medical device incorporating same
US9402569B2 (en) 2010-10-28 2016-08-02 Medtronic Minimed, Inc. System and/or method for glucose sensor calibration
US8353869B2 (en) * 2010-11-02 2013-01-15 Baxa Corporation Anti-tampering apparatus and method for drug delivery devices
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
JP4685198B1 (ja) * 2010-11-11 2011-05-18 株式会社アルテ 包装用プレート、注射器保持容器及び容器兼用注射器の製造方法
TWI425719B (zh) 2010-11-16 2014-02-01 Compal Electronics Inc 連接埠
US8446733B2 (en) 2010-11-24 2013-05-21 Lear Corporation Printed circuit board connection assembly
WO2012072559A1 (en) 2010-11-29 2012-06-07 Sanofi-Aventis Deutschland Gmbh Auto-injector device with a medicated module
US8795230B2 (en) 2010-11-30 2014-08-05 Becton, Dickinson And Company Adjustable height needle infusion device
GB201020472D0 (en) 2010-12-02 2011-01-19 Oval Medical Technologies Ltd A drive assembly for an autoinjector
EP2468332A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2468331A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
US8690855B2 (en) 2010-12-22 2014-04-08 Medtronic Minimed, Inc. Fluid reservoir seating procedure for a fluid infusion device
CN201941304U (zh) 2010-12-22 2011-08-24 刘天野 具有报警功能的档案盒
US8628510B2 (en) 2010-12-22 2014-01-14 Medtronic Minimed, Inc. Monitoring the operating health of a force sensor in a fluid infusion device
US8197444B1 (en) 2010-12-22 2012-06-12 Medtronic Minimed, Inc. Monitoring the seating status of a fluid reservoir in a fluid infusion device
US8469942B2 (en) 2010-12-22 2013-06-25 Medtronic Minimed, Inc. Occlusion detection for a fluid infusion device
EP3473283B1 (en) 2011-01-24 2020-12-09 AbbVie Biotechnology Ltd. Removal of needle shields from syringes and automatic injection devices
EP2489383A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489381A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
GB2488579A (en) 2011-03-02 2012-09-05 Owen Mumford Ltd Autoinjector with "injection complete" indicator
USD702834S1 (en) 2011-03-22 2014-04-15 Medimop Medical Projects Ltd. Cartridge for use in injection device
GB2486748B (en) 2011-03-24 2013-04-10 Owen Mumford Ltd Autoinjector devices
AU2012245211B2 (en) 2011-04-21 2016-03-10 Abbvie Inc. Wearable automatic injection device
US8795231B2 (en) 2011-05-10 2014-08-05 Medtronic Minimed, Inc. Automated reservoir fill system
WO2012160164A1 (en) 2011-05-25 2012-11-29 Sanofi-Aventis Deutschland Gmbh Handheld medicament injection device with illuminated dose button
EP2714152B1 (en) 2011-05-25 2017-12-20 Sanofi-Aventis Deutschland GmbH Medicament delivery device with cap
WO2012160157A1 (en) 2011-05-25 2012-11-29 Sanofi-Aventis Deutschland Gmbh Medicament injection device and priming operation
EP2714157B1 (en) 2011-06-02 2016-08-10 UCB Biopharma SPRL Auto-injector
GB201109620D0 (en) 2011-06-09 2011-07-20 Ardehali Massoud H Injection apparatus
US8292647B1 (en) 2011-06-13 2012-10-23 Tyco Electronics Corporation Socket connector
US9623188B2 (en) 2011-07-07 2017-04-18 Novo Nordisk A/S Drug delivery injection pen with add-on dose capturing and display module
WO2013013081A1 (en) * 2011-07-20 2013-01-24 Stryker Corporaton Manifold for filling plural cannulae
US20140194854A1 (en) 2011-08-29 2014-07-10 Sid Technologies Llc Subcutaneous and intradermal patch infusers
PL2902058T3 (pl) 2011-08-31 2020-11-02 Shl Medical Ag Urządzenie wstrzykujące
USD657462S1 (en) 2011-09-02 2012-04-10 I & J Fisnar, Inc. Liquid dispensing syringe barrel
US10076649B2 (en) 2011-09-07 2018-09-18 3M Innovative Properties Company Delivery system for hollow microneedle arrays
PT3412323T (pt) 2011-09-09 2021-02-22 Merck Patent Gmbh Um autoinjetor para injeção de epinefrina
EP2574355A1 (en) 2011-09-27 2013-04-03 Sanofi-Aventis Deutschland GmbH Package for a medicament delivery device
US9597455B2 (en) 2011-09-30 2017-03-21 Becton Dickinson France S.A.S. Syringe having a spring action plunger rod
KR20130038503A (ko) 2011-10-10 2013-04-18 삼성전자주식회사 전자장치의 ｐｂａ 적층구조
CN202236675U (zh) 2011-10-11 2012-05-30 张晓燕 无残留注射器
US9687614B2 (en) * 2011-10-14 2017-06-27 Sanofi-Aventis Deutschland Gmbh Assembly for a drug delivery device
EP2768560B1 (en) * 2011-10-17 2016-09-07 SHL Group AB Device for removing delivery member shields
US8603028B2 (en) 2011-11-18 2013-12-10 Allergan, Inc. Injection device having an angled tip portion
EP2596823A1 (en) 2011-11-24 2013-05-29 Sanofi-Aventis Deutschland GmbH Autoinjector
EP2596822A1 (en) 2011-11-24 2013-05-29 Sanofi-Aventis Deutschland GmbH Autoinjector
US10722645B2 (en) 2011-12-21 2020-07-28 Deka Products Limited Partnership Syringe pump, and related method and system
US20130172808A1 (en) 2011-12-30 2013-07-04 G. Ford Gilbert Medical infusion device producing adenosine triphosphate from carbohydrates
US10335545B2 (en) 2012-01-31 2019-07-02 West Pharma. Services IL, Ltd. Time dependent drug delivery apparatus
DK2819724T3 (da) 2012-02-27 2019-05-27 Hoffmann La Roche Fjederkraftsamling til forspænding eller aktivering af propper i sprøjter, patroner til injektionspenne og lignende
US8603026B2 (en) 2012-03-20 2013-12-10 Medtronic Minimed, Inc. Dynamic pulse-width modulation motor control and medical device incorporating same
US8523803B1 (en) 2012-03-20 2013-09-03 Medtronic Minimed, Inc. Motor health monitoring and medical device incorporating same
US8603027B2 (en) 2012-03-20 2013-12-10 Medtronic Minimed, Inc. Occlusion detection using pulse-width modulation and medical device incorporating same
US9072827B2 (en) 2012-03-26 2015-07-07 Medimop Medical Projects Ltd. Fail safe point protector for needle safety flap
US9463280B2 (en) 2012-03-26 2016-10-11 Medimop Medical Projects Ltd. Motion activated septum puncturing drug delivery device
EP2650032A1 (en) 2012-04-11 2013-10-16 PharmaSens AG Subcutaneous needle insertion mechanism
GB201206766D0 (en) 2012-04-17 2012-05-30 Univ Antwerpen Prefillable intradermal delivery device
EP2844319B1 (en) 2012-04-30 2016-08-31 ConceptoMed AS Fluid transfer devices
US20130296824A1 (en) 2012-05-03 2013-11-07 Uc Biodevices Corporation Microneedle based transdermal drug delivery device and method
US9849252B2 (en) 2012-05-04 2017-12-26 Sofia Eleni Armes Electromechanical manipulating device for medical needle and syringe with sensory biofeedback and pain suppression capability
US20150157806A1 (en) 2012-07-04 2015-06-11 Vigmed Ab Injection needle
CN104411350B (zh) 2012-07-05 2017-06-13 尤尼特拉克特注射器控股有限公司 驱动控制机构及用于可注射匣的自动注射器
JP6069936B2 (ja) 2012-08-01 2017-02-01 株式会社ジェイ・エム・エス 輸液セット
CN104519931B (zh) 2012-08-10 2017-10-20 赛诺菲-安万特德国有限公司 包括注射装置和附加装置的系统
US8808269B2 (en) 2012-08-21 2014-08-19 Medtronic Minimed, Inc. Reservoir plunger position monitoring and medical device incorporating same
EP2712650A1 (en) 2012-09-27 2014-04-02 F. Hoffmann-La Roche AG Adapter and drug cartridge alignment device
US9539384B2 (en) 2012-09-28 2017-01-10 Animas Corporation Telescoping piston drive for medical infusion device
US9789250B2 (en) 2012-10-05 2017-10-17 Becton, Dickinson And Company Infusion set with safety device
US8870818B2 (en) 2012-11-15 2014-10-28 Medtronic Minimed, Inc. Systems and methods for alignment and detection of a consumable component
CN203044048U (zh) 2012-12-18 2013-07-10 项利仙 试管架定位装置和试管移送装置
US9421323B2 (en) 2013-01-03 2016-08-23 Medimop Medical Projects Ltd. Door and doorstop for portable one use drug delivery apparatus
US9033924B2 (en) 2013-01-18 2015-05-19 Medtronic Minimed, Inc. Systems for fluid reservoir retention
US9107994B2 (en) 2013-01-18 2015-08-18 Medtronic Minimed, Inc. Systems for fluid reservoir retention
US9522223B2 (en) 2013-01-18 2016-12-20 Medtronic Minimed, Inc. Systems for fluid reservoir retention
US9089475B2 (en) 2013-01-23 2015-07-28 Icu Medical, Inc. Pressure-regulating vial adaptors
WO2014116274A1 (en) 2013-01-25 2014-07-31 Unitract Syringe Pty Ltd Integrated sliding seal fluid pathway connection and drug containers for drug delivery pumps
US20140214001A1 (en) 2013-01-31 2014-07-31 Alpimed Sarl Fluid dispensing device
US9308321B2 (en) 2013-02-18 2016-04-12 Medtronic Minimed, Inc. Infusion device having gear assembly initialization
JP6163198B2 (ja) 2013-02-28 2017-07-12 テルモ株式会社 キャップ
US9814871B2 (en) 2013-03-15 2017-11-14 Bayer Healthcare Llc Connector assembly for syringe system
US8979802B2 (en) 2013-03-15 2015-03-17 B. Braun Melsungen Ag Safety IV catheter assembly with seal
TW201509464A (zh) 2013-04-10 2015-03-16 Sanofi Sa 注射裝置及組裝方法
WO2014166904A1 (en) 2013-04-10 2014-10-16 Sanofi Hand-held drug injection device and dose setting limiter mechanism therefor
US9750882B2 (en) 2013-04-22 2017-09-05 Sanofi-Aventis Deutschland Gmbh Supplemental device for attachment to an injection device
US9011164B2 (en) 2013-04-30 2015-04-21 Medimop Medical Projects Ltd. Clip contact for easy installation of printed circuit board PCB
EP2991705B1 (en) 2013-05-01 2019-10-16 UNL Holdings LLC Plunger-driven auto-injectors
MX2015015089A (es) 2013-05-03 2016-02-11 Becton Dickinson Co Subconjunto de trayectoria de flujo.
CN105492037A (zh) 2013-05-30 2016-04-13 韦贝尔Cds公司 给送流体至患者的装置
EP3003438B1 (en) 2013-05-31 2019-05-22 Valeritas, Inc. A fluid delivery device having an insertable prefilled cartridge
US9539757B2 (en) 2013-06-26 2017-01-10 Tekni-Plex, Inc. Packing tray having cell pockets with expandable sidewalls and floating base, and method of manufacture
US20150005703A1 (en) 2013-06-28 2015-01-01 Animas Corporation Drug infusion device with safety interlock
EP2823837A1 (en) 2013-07-09 2015-01-14 Sanofi-Aventis Deutschland GmbH Autoinjector
EP2832390A1 (en) 2013-07-30 2015-02-04 Sensile Pat AG Drug delivery device with needle actuation mechanism
GB201313782D0 (en) 2013-08-01 2013-09-18 Oval Medical Technologies Ltd Drug delivery device
WO2015022787A1 (ja) 2013-08-14 2015-02-19 テルモ株式会社 注射器
EP3041527B1 (en) 2013-09-05 2018-05-09 Sanofi-Aventis Deutschland GmbH Drive mechanism for a needle insertion arrangement
JP6487444B2 (ja) 2013-09-05 2019-03-20 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 針挿入配置のための駆動機構
TR201902021T4 (tr) 2013-09-05 2019-03-21 Sanofi Aventis Deutschland Manüel olarak tetiklemeli, yay yüklü tahrik mekanizması ile iğne insersiyon ve retraksiyon düzeni.
US9119939B2 (en) * 2013-09-12 2015-09-01 Michael J. Botich Rotatable hypodermic needle and method of use
US20160228652A1 (en) 2013-09-30 2016-08-11 Medimop Medical Projects Ltd. Needle retraction mechanism for autoinjector
WO2015048799A1 (en) 2013-09-30 2015-04-02 Medimop Medical Projects Ltd. Needle retraction mechanism for autoinjector
US20150112278A1 (en) 2013-10-21 2015-04-23 Optima MDevice Technology Corporation Systems and Methods for Needle for Subclavian Vein Penetration
TWI569832B (zh) 2013-10-23 2017-02-11 卡貝歐洲有限公司 藥物輸送裝置
US9463889B2 (en) 2013-10-25 2016-10-11 Medtronic, Inc. Prefilled reservoir apparatus for ambulatory infusion device
DE102013112167A1 (de) 2013-11-05 2015-05-07 Schott Ag Haltestruktur zum gleichzeitigen Halten einer Mehrzahl von Behältern für Substanzen für medizinische, pharmazeutische oder kosmetische Anwendungen sowie Transport- und Verpackungsbehälter mit Selbiger sowie Verfahren
EP2878321A1 (en) 2013-11-28 2015-06-03 Sanofi-Aventis Deutschland GmbH Needle safety device and drug delivery device
DK3391918T3 (da) 2013-12-20 2021-12-13 Sanofi Aventis Deutschland Engangs-afgivelsesenhed til medicinafgivelsesanordning
EP2886144A1 (en) 2013-12-20 2015-06-24 Sanofi-Aventis Deutschland GmbH Drug delivery device
PL3099374T3 (pl) 2014-01-31 2018-08-31 Industrie Borla S.P.A. Złącze zaworowe do przewodów medycznych
JP2017510391A (ja) 2014-02-03 2017-04-13 ノボ・ノルデイスク・エー／エス 伸縮式駆動機構
GB201402261D0 (en) 2014-02-10 2014-03-26 Owen Mumford Ltd Injector apparatus
CN105979990A (zh) 2014-02-17 2016-09-28 诺和诺德股份有限公司 具有欧氏耦接器的伸缩式驱动布置结构
EP3113777A4 (en) 2014-03-04 2017-09-06 The Children's Hospital of Philadelphia Methods for managing care of patients predisposed to progressive mitral valve diseases
TWI616218B (zh) 2014-03-06 2018-03-01 卡貝歐洲有限公司 輸送藥物的裝置
JP6275291B2 (ja) 2014-03-12 2018-02-07 ウェイ，ミン 薬物自動注射器
WO2015163009A1 (ja) 2014-04-25 2015-10-29 パナソニックヘルスケアホールディングス株式会社 薬剤注入装置
GB2530714A (en) 2014-08-20 2016-04-06 Owen Mumford Ltd Injection devices
WO2016036574A1 (en) 2014-09-02 2016-03-10 Eli Lilly And Company Sensing system for detecting a piston in a medical fluid container
GB2532300B (en) 2014-09-30 2018-09-19 Owen Mumford Ltd Injection devices
WO2016071174A1 (en) 2014-11-04 2016-05-12 Carebay Europe Ltd Autoinjector with delayed signal of complete medication delivery
US20160144117A1 (en) 2014-11-21 2016-05-26 Thomas Chun Hypodermic syringe that automatically ejects medicament from a needle
EP3028947A1 (en) 2014-12-05 2016-06-08 F. Hoffmann-La Roche AG Closing a chamber of a container for a pharmaceutical product
EP3028946A1 (en) 2014-12-05 2016-06-08 F. Hoffmann-La Roche AG Preparing a double chamber container
WO2016100781A1 (en) 2014-12-19 2016-06-23 Amgen Inc. Drug delivery device with proximity sensor
WO2016141082A1 (en) 2015-03-02 2016-09-09 Unitract Syringe Pty Ltd Device and method for making aseptic connections
US10293120B2 (en) 2015-04-10 2019-05-21 West Pharma. Services IL, Ltd. Redundant injection device status indication
US10149943B2 (en) 2015-05-29 2018-12-11 West Pharma. Services IL, Ltd. Linear rotation stabilizer for a telescoping syringe stopper driverdriving assembly
TW201707740A (zh) 2015-06-03 2017-03-01 賽諾菲阿凡提斯德意志有限公司 藥物輸送裝置（四）
JP6703813B2 (ja) 2015-08-06 2020-06-03 国立大学法人横浜国立大学 冷却装置、およびモータ
DE102016201268A1 (de) 2016-01-28 2017-08-03 Schott Schweiz Ag Trägerplatte für pharmazeutische Behältnisse
JOP20170042B1 (ar) 2016-02-12 2022-09-15 Amgen Inc وسيلة توصيل عقار، طريقة تصنيعه وطريقة استخدامه
WO2017161076A1 (en) 2016-03-16 2017-09-21 Medimop Medical Projects Ltd. Staged telescopic screw assembly having different visual indicators
US10376647B2 (en) 2016-03-18 2019-08-13 West Pharma. Services IL, Ltd. Anti-rotation mechanism for telescopic screw assembly
JP6724133B2 (ja) 2016-03-30 2020-07-15 テルモ株式会社 薬液投与装置
CN105749383B (zh) 2016-04-21 2017-03-08 北京甘甘科技有限公司 预填充笔式注射器
EP3260147A1 (en) 2016-06-23 2017-12-27 TecPharma Licensing AG A segmented piston rod for a medication delivery device
US10898658B2 (en) 2016-07-06 2021-01-26 LynJohnston, LLC Compact injection device with telescoping components
FR3055216A1 (fr) 2016-08-31 2018-03-02 Nemera La Verpilliere Dispositif d'injection automatique a agencement optimise
USD838367S1 (en) 2016-09-26 2019-01-15 West Pharma. Services IL, Ltd. Syringe barrel
CN110520175B (zh) 2017-01-20 2022-03-29 L.G.P.科技控股有限公司 自动注射器装置
GB2560524B (en) 2017-03-13 2019-07-31 Univ Cape Town An auto-injector
GB201704143D0 (en) 2017-03-15 2017-04-26 Owen Mumford Ltd Low force trigger
WO2018222521A1 (en) 2017-05-30 2018-12-06 West Pharma. Services IL, Ltd. Modular drive train for wearable injector
EP3714922B1 (en) 2017-07-07 2022-05-18 Neuroderm Ltd Device for subcutaneous delivery of fluid medicament
US20190071217A1 (en) 2017-09-01 2019-03-07 Pinnpack Packaging, Llc Cup cake tray
EP3659650B1 (en) 2017-09-29 2024-07-03 Terumo Kabushiki Kaisha Plunger assembly, drug solution dosage device, and driving method of plunger assembly
AU2019273834B2 (en) 2018-05-24 2022-03-03 Novartis Ag Automatic drug delivery device
KR102549081B1 (ko) 2018-12-14 2023-07-03 에스에이치엘 메디컬 아게 자동 주사기
CN116726317A (zh) 2019-03-22 2023-09-12 辉美医疗器械有限公司 自动注射装置及自动注射装置系统
US11278669B2 (en) 2020-01-21 2022-03-22 Repro Med Systems, Inc. Gear-driven infusion assemblies, systems, and methods

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997021457A1 (en) * 1995-12-11 1997-06-19 Elan Medical Technologies Limited Cartridge-based drug delivery device

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