CN107375291A - 用于治疗高胆血症和胆汁淤积性肝病的胆汁酸再循环抑制剂 - Google Patents

用于治疗高胆血症和胆汁淤积性肝病的胆汁酸再循环抑制剂 Download PDF

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CN107375291A
CN107375291A CN201710153159.0A CN201710153159A CN107375291A CN 107375291 A CN107375291 A CN 107375291A CN 201710153159 A CN201710153159 A CN 201710153159A CN 107375291 A CN107375291 A CN 107375291A
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alkyl
substituted
aryl
heterocycle
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布罗尼斯拉娃·格杜林
迈克尔·格雷
尼尔·奥唐奈
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Shire Human Genetics Therapies Inc
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Lu Meina Pharmaceuticals
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    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
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    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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CN201710153159.0A 2011-10-28 2012-10-26 用于治疗高胆血症和胆汁淤积性肝病的胆汁酸再循环抑制剂 Pending CN107375291A (zh)

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Application Number Priority Date Filing Date Title
US201161553094P 2011-10-28 2011-10-28
US61/553,094 2011-10-28
US201261607487P 2012-03-06 2012-03-06
US61/607,487 2012-03-06
CN201280065567.6A CN104023718B (zh) 2011-10-28 2012-10-26 用于治疗高胆血症和胆汁淤积性肝病的胆汁酸再循环抑制剂

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