CN102575227A - 表达多种免疫调节剂的工程改造细胞及其应用 - Google Patents

表达多种免疫调节剂的工程改造细胞及其应用 Download PDF

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CN102575227A
CN102575227A CN200980150164XA CN200980150164A CN102575227A CN 102575227 A CN102575227 A CN 102575227A CN 200980150164X A CN200980150164X A CN 200980150164XA CN 200980150164 A CN200980150164 A CN 200980150164A CN 102575227 A CN102575227 A CN 102575227A
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ligand
protein
cells
promoter
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R·P·比奇
T·D·瑞德
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University of Pittsburgh
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University of Pittsburgh
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CN200980150164XA 2008-10-08 2009-10-08 表达多种免疫调节剂的工程改造细胞及其应用 Pending CN102575227A (zh)

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US10381008P 2008-10-08 2008-10-08
US61/103,810 2008-10-08
PCT/US2009/005510 WO2010042189A2 (en) 2008-10-08 2009-10-08 Engineered cells expressing multiple immunomodulators and uses thereof

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CN102575227A true CN102575227A (zh) 2012-07-11

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US (4) US9492482B2 (enExample)
EP (1) EP2356219A4 (enExample)
JP (3) JP2012504959A (enExample)
KR (2) KR101361416B1 (enExample)
CN (1) CN102575227A (enExample)
AU (3) AU2009302804B2 (enExample)
BR (1) BRPI0920679A2 (enExample)
CA (1) CA2739902A1 (enExample)
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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105307725A (zh) * 2013-04-11 2016-02-03 布里格姆及妇女医院股份有限公司 治疗自身免疫疾病的方法和组合物
CN106029889A (zh) * 2013-11-22 2016-10-12 德那翠丝有限公司 表达免疫细胞刺激受体激动剂的腺病毒
CN109153989A (zh) * 2016-03-17 2019-01-04 国立大学法人山口大学 表达免疫功能调控因子的免疫活性细胞及表达载体
WO2019144945A1 (en) * 2018-01-25 2019-08-01 I-Mab Anti-pd-l1 antibody and il-7 fusions
CN110354260A (zh) * 2019-08-19 2019-10-22 启辰生生物科技(珠海)有限公司 免疫增强剂、药物组合物及其应用
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US20110268766A1 (en) 2011-11-03
RU2011113660A (ru) 2012-11-20
RU2573912C2 (ru) 2016-01-27
JP2016025858A (ja) 2016-02-12
AU2015234302A1 (en) 2015-10-29
EP2356219A2 (en) 2011-08-17
US20180333486A1 (en) 2018-11-22

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Application publication date: 20120711