CN102575227A - 表达多种免疫调节剂的工程改造细胞及其应用 - Google Patents

表达多种免疫调节剂的工程改造细胞及其应用 Download PDF

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CN102575227A
CN102575227A CN200980150164XA CN200980150164A CN102575227A CN 102575227 A CN102575227 A CN 102575227A CN 200980150164X A CN200980150164X A CN 200980150164XA CN 200980150164 A CN200980150164 A CN 200980150164A CN 102575227 A CN102575227 A CN 102575227A
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transcription factor
ligand
protein
cells
promoter
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R·P·比奇
T·D·瑞德
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University of Pittsburgh
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CN200980150164XA 2008-10-08 2009-10-08 表达多种免疫调节剂的工程改造细胞及其应用 Pending CN102575227A (zh)

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US10381008P 2008-10-08 2008-10-08
US61/103,810 2008-10-08
PCT/US2009/005510 WO2010042189A2 (en) 2008-10-08 2009-10-08 Engineered cells expressing multiple immunomodulators and uses thereof

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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105307725A (zh) * 2013-04-11 2016-02-03 布里格姆及妇女医院股份有限公司 治疗自身免疫疾病的方法和组合物
CN106029889A (zh) * 2013-11-22 2016-10-12 德那翠丝有限公司 表达免疫细胞刺激受体激动剂的腺病毒
CN109153989A (zh) * 2016-03-17 2019-01-04 国立大学法人山口大学 表达免疫功能调控因子的免疫活性细胞及表达载体
WO2019144945A1 (en) * 2018-01-25 2019-08-01 I-Mab Anti-pd-l1 antibody and il-7 fusions
CN110354260A (zh) * 2019-08-19 2019-10-22 启辰生生物科技(珠海)有限公司 免疫增强剂、药物组合物及其应用
CN110732021A (zh) * 2019-11-21 2020-01-31 北京启辰生生物科技有限公司 用于解除肿瘤免疫抑制的组合物及其应用
CN110904050A (zh) * 2019-12-16 2020-03-24 启辰生生物科技(珠海)有限公司 工程化抗原递呈细胞、免疫调节组合物及应用
CN112029730A (zh) * 2020-05-20 2020-12-04 深圳市芥至和生物科技有限公司 一种基因修饰的间充质干细胞及其应用
CN112481211A (zh) * 2015-01-26 2021-03-12 菲特治疗公司 免疫调节性提高的细胞及其使用和生产方法
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Application publication date: 20120711