MX340972B - Celulas manipuladas por ingenieria que expresan multiples inmunomoduladores, y uso de las mismas. - Google Patents

Celulas manipuladas por ingenieria que expresan multiples inmunomoduladores, y uso de las mismas.

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Publication number
MX340972B
MX340972B MX2011003762A MX2011003762A MX340972B MX 340972 B MX340972 B MX 340972B MX 2011003762 A MX2011003762 A MX 2011003762A MX 2011003762 A MX2011003762 A MX 2011003762A MX 340972 B MX340972 B MX 340972B
Authority
MX
Mexico
Prior art keywords
cells expressing
engineered cells
expressing multiple
immunomodulators
multiple immunomodulators
Prior art date
Application number
MX2011003762A
Other languages
English (en)
Other versions
MX2011003762A (es
Inventor
d reed Thomas
Patterson Beech Robert
Original Assignee
Intrexon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intrexon Corp filed Critical Intrexon Corp
Publication of MX2011003762A publication Critical patent/MX2011003762A/es
Publication of MX340972B publication Critical patent/MX340972B/es

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    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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Abstract

La presente invención se refiere al campo de los agentes terapéuticos. Más específicamente, la invención proporciona los métodos para generar células inmunitarias manipuladas in vitro, que expresan condicionalmente interleucina 12 (IL-12) y uno o más inmunomoduladores bajo el control de un sistema de modulación de expresión en gen, en presencia del ligando de activación, y los usos para propósitos terapéuticos en animales.
MX2011003762A 2008-10-08 2009-10-08 Celulas manipuladas por ingenieria que expresan multiples inmunomoduladores, y uso de las mismas. MX340972B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10381008P 2008-10-08 2008-10-08
PCT/US2009/005510 WO2010042189A2 (en) 2008-10-08 2009-10-08 Engineered cells expressing multiple immunomodulators and uses thereof

Publications (2)

Publication Number Publication Date
MX2011003762A MX2011003762A (es) 2011-04-27
MX340972B true MX340972B (es) 2016-08-02

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Application Number Title Priority Date Filing Date
MX2011003762A MX340972B (es) 2008-10-08 2009-10-08 Celulas manipuladas por ingenieria que expresan multiples inmunomoduladores, y uso de las mismas.

Country Status (12)

Country Link
US (4) US9492482B2 (es)
EP (1) EP2356219A4 (es)
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