CN102203258A - TGF-β拮抗剂多靶点结合蛋白 - Google Patents

TGF-β拮抗剂多靶点结合蛋白 Download PDF

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CN102203258A
CN102203258A CN2009801348955A CN200980134895A CN102203258A CN 102203258 A CN102203258 A CN 102203258A CN 2009801348955 A CN2009801348955 A CN 2009801348955A CN 200980134895 A CN200980134895 A CN 200980134895A CN 102203258 A CN102203258 A CN 102203258A
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domain
binding
domains
seq
antagonist
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A·K·露奎斯特
P·R·包姆
P·A·汤普森
L·米舍
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Aptevo Research and Development LLC
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Emergent Product Development Seattle LLC
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
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CN2009801348955A 2008-07-02 2009-07-02 TGF-β拮抗剂多靶点结合蛋白 Pending CN102203258A (zh)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US13408908P 2008-07-02 2008-07-02
US13409108P 2008-07-02 2008-07-02
US13408708P 2008-07-02 2008-07-02
US13408608P 2008-07-02 2008-07-02
US13408508P 2008-07-02 2008-07-02
US13409008P 2008-07-02 2008-07-02
US13408808P 2008-07-02 2008-07-02
US61/134,091 2008-07-02
US61/134,089 2008-07-02
US61/134,090 2008-07-02
US61/134,086 2008-07-02
US61/134,087 2008-07-02
US61/134,088 2008-07-02
US61/134,085 2008-07-02
US18123209P 2009-05-26 2009-05-26
US61/181,232 2009-05-26
PCT/US2009/049616 WO2010003118A1 (en) 2008-07-02 2009-07-02 Tgf-b antagonist multi-target binding proteins

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CN102203258A true CN102203258A (zh) 2011-09-28

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EP (1) EP2310508A1 (enExample)
JP (1) JP2011526794A (enExample)
KR (1) KR20110044992A (enExample)
CN (1) CN102203258A (enExample)
AU (1) AU2009266873A1 (enExample)
CA (1) CA2729810A1 (enExample)
EA (1) EA201170031A1 (enExample)
IL (1) IL210268A0 (enExample)
MX (1) MX2011000039A (enExample)
NZ (1) NZ590667A (enExample)
WO (1) WO2010003118A1 (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104974262A (zh) * 2014-04-04 2015-10-14 华博生物医药技术（上海）有限公司 新型重组双功能融合蛋白及其制法和用途
CN113388638A (zh) * 2021-04-13 2021-09-14 中国人民解放军西部战区总医院 一种同时结合TGFβ和VEGF的双靶点融合蛋白质粒的构建方法
CN113429488A (zh) * 2021-07-14 2021-09-24 海正生物制药有限公司 GITR/TGF-β双靶向融合蛋白及其用途
CN115135302A (zh) * 2019-12-20 2022-09-30 阿雷斯贸易股份有限公司 IgG:TGFβRII融合蛋白组合物
CN116284449A (zh) * 2023-02-27 2023-06-23 深圳市先康达生命科学有限公司 增强型TGF-βR嵌合受体及其应用
CN116496407A (zh) * 2022-01-25 2023-07-28 赋生康(上海)生物科技有限公司 一种双功能融合蛋白及其制备方法和应用

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US20110177070A1 (en) 2011-07-21
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MX2011000039A (es) 2011-05-31

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