CN101228161B - 适用作蛋白激酶抑制剂的吡咯并吡啶类 - Google Patents

适用作蛋白激酶抑制剂的吡咯并吡啶类 Download PDF

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Publication number
CN101228161B
CN101228161B CN2006800263918A CN200680026391A CN101228161B CN 101228161 B CN101228161 B CN 101228161B CN 2006800263918 A CN2006800263918 A CN 2006800263918A CN 200680026391 A CN200680026391 A CN 200680026391A CN 101228161 B CN101228161 B CN 101228161B
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China
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compound
disease
group
pyrrolo
pyridin
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Expired - Fee Related
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CN2006800263918A
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Chinese (zh)
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CN101228161A (zh
Inventor
M·W·里德博尔
M·W·万纳梅克
L·J·法默
王天生
A·C·皮尔斯
G·马蒂内兹-伯塔拉
R·S·贝希尔
G·W·比米斯
王健
F·G·萨里图罗
M·J·阿诺斯特
J·H·科姆
J·格林
M·斯特沃特
C·马赫夫卡
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • C07—ORGANIC CHEMISTRY
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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CN2006800263918A 2005-05-20 2006-05-22 适用作蛋白激酶抑制剂的吡咯并吡啶类 Expired - Fee Related CN101228161B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68355405P 2005-05-20 2005-05-20
US60/683,554 2005-05-20
PCT/US2006/019711 WO2006127587A1 (en) 2005-05-20 2006-05-22 Pyrrolopyridines useful as inhibitors of protein kinase

Publications (2)

Publication Number Publication Date
CN101228161A CN101228161A (zh) 2008-07-23
CN101228161B true CN101228161B (zh) 2012-10-10

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US (1) US8921376B2 (enExample)
EP (3) EP2354140A1 (enExample)
JP (3) JP2008545660A (enExample)
KR (1) KR20080016659A (enExample)
CN (1) CN101228161B (enExample)
AT (1) ATE540948T1 (enExample)
AU (1) AU2006251623A1 (enExample)
CA (1) CA2609126A1 (enExample)
ES (1) ES2380795T3 (enExample)
IL (1) IL187438A0 (enExample)
MX (1) MX2007014619A (enExample)
NO (1) NO20076502L (enExample)
NZ (1) NZ564065A (enExample)
RU (2) RU2435769C2 (enExample)
WO (1) WO2006127587A1 (enExample)
ZA (1) ZA200710379B (enExample)

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