CL2012000581A1 - Proceso para la preparacion de 1-cloro-4-(ß-d-glucopiranos-1-il)-2-[4-tetrahidrofuran-3-iloxi-bencil]-benceno con separacion de fases mediada por la adicion de acidos. - Google Patents

Proceso para la preparacion de 1-cloro-4-(ß-d-glucopiranos-1-il)-2-[4-tetrahidrofuran-3-iloxi-bencil]-benceno con separacion de fases mediada por la adicion de acidos.

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Publication number
CL2012000581A1
CL2012000581A1 CL2012000581A CL2012000581A CL2012000581A1 CL 2012000581 A1 CL2012000581 A1 CL 2012000581A1 CL 2012000581 A CL2012000581 A CL 2012000581A CL 2012000581 A CL2012000581 A CL 2012000581A CL 2012000581 A1 CL2012000581 A1 CL 2012000581A1
Authority
CL
Chile
Prior art keywords
benzyl
benzene
glucopyranos
yloxy
tetrahydrofuran
Prior art date
Application number
CL2012000581A
Other languages
English (en)
Spanish (es)
Inventor
Rainer Hamm
Dirk Weber
Svenja Renner
Christian Filser
Tobias Fiedler
Simone Orlich
Matthias Post
Xiao-Jun Wang
Thomas Wirth
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of CL2012000581A1 publication Critical patent/CL2012000581A1/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • C07H1/06Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04Carbocyclic radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Packaging Of Annular Or Rod-Shaped Articles, Wearing Apparel, Cassettes, Or The Like (AREA)
  • Wrapping Of Specific Fragile Articles (AREA)
CL2012000581A 2009-09-30 2012-03-02 Proceso para la preparacion de 1-cloro-4-(ß-d-glucopiranos-1-il)-2-[4-tetrahidrofuran-3-iloxi-bencil]-benceno con separacion de fases mediada por la adicion de acidos. CL2012000581A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24714409P 2009-09-30 2009-09-30

Publications (1)

Publication Number Publication Date
CL2012000581A1 true CL2012000581A1 (es) 2012-08-03

Family

ID=43736212

Family Applications (1)

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CL2012000581A CL2012000581A1 (es) 2009-09-30 2012-03-02 Proceso para la preparacion de 1-cloro-4-(ß-d-glucopiranos-1-il)-2-[4-tetrahidrofuran-3-iloxi-bencil]-benceno con separacion de fases mediada por la adicion de acidos.

Country Status (25)

Country Link
US (2) US9024010B2 (enExample)
EP (1) EP2486029B1 (enExample)
JP (1) JP5758900B2 (enExample)
KR (1) KR101813025B1 (enExample)
CN (1) CN102574829B (enExample)
AR (1) AR078193A1 (enExample)
AU (1) AU2010303124B2 (enExample)
BR (1) BR112012007085B8 (enExample)
CA (1) CA2775962C (enExample)
CL (1) CL2012000581A1 (enExample)
DK (1) DK2486029T3 (enExample)
EA (1) EA022032B1 (enExample)
ES (1) ES2546762T3 (enExample)
HR (1) HRP20150945T1 (enExample)
HU (1) HUE026133T2 (enExample)
IL (1) IL218101A0 (enExample)
IN (1) IN2012DN02751A (enExample)
MX (1) MX2012003048A (enExample)
NZ (1) NZ598366A (enExample)
PH (1) PH12012500634A1 (enExample)
PL (1) PL2486029T3 (enExample)
PT (1) PT2486029E (enExample)
SI (1) SI2486029T1 (enExample)
TW (1) TWI465458B (enExample)
WO (1) WO2011039108A2 (enExample)

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CA2775962A1 (en) 2011-04-07
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