CH628628A5 - Process for the preparation of cyclic compounds - Google Patents

Process for the preparation of cyclic compounds Download PDF

Info

Publication number
CH628628A5
CH628628A5 CH954377A CH954377A CH628628A5 CH 628628 A5 CH628628 A5 CH 628628A5 CH 954377 A CH954377 A CH 954377A CH 954377 A CH954377 A CH 954377A CH 628628 A5 CH628628 A5 CH 628628A5
Authority
CH
Switzerland
Prior art keywords
solution
carbomethoxy
formula
amino
hydrochloride
Prior art date
Application number
CH954377A
Other languages
German (de)
English (en)
Inventor
Pasquale Nicholas Confalone
Giacomo Pizzolato
Marianne Rouge
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH628628A5 publication Critical patent/CH628628A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH954377A 1976-08-23 1977-08-03 Process for the preparation of cyclic compounds CH628628A5 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71685476A 1976-08-23 1976-08-23
US71685376A 1976-08-23 1976-08-23
US82052177A 1977-08-01 1977-08-01

Publications (1)

Publication Number Publication Date
CH628628A5 true CH628628A5 (en) 1982-03-15

Family

ID=27418961

Family Applications (1)

Application Number Title Priority Date Filing Date
CH954377A CH628628A5 (en) 1976-08-23 1977-08-03 Process for the preparation of cyclic compounds

Country Status (21)

Country Link
JP (1) JPS5340755A (xx)
AR (1) AR222453A1 (xx)
AT (1) AT359486B (xx)
AU (1) AU509956B2 (xx)
BE (1) BE858012A (xx)
CH (1) CH628628A5 (xx)
DE (1) DE2737738C2 (xx)
DK (1) DK150484C (xx)
ES (1) ES461796A1 (xx)
FI (1) FI66859C (xx)
FR (1) FR2365566A1 (xx)
GB (1) GB1587084A (xx)
HU (1) HU179484B (xx)
IE (1) IE45470B1 (xx)
IL (1) IL52792A (xx)
IT (1) IT1143757B (xx)
LU (1) LU78003A1 (xx)
MC (1) MC1156A1 (xx)
NL (1) NL7709246A (xx)
NO (1) NO148673C (xx)
NZ (1) NZ184981A (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6232765Y2 (xx) * 1981-02-28 1987-08-21
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
CA2162586C (en) 1993-05-13 2006-01-03 David J. Grainger Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells
AU6959898A (en) * 1997-04-11 1998-11-11 David J. Grainger Compounds and therapies for the prevention of vascular and non-vascular pathol ogies
DE102004063191A1 (de) 2004-12-29 2006-07-13 Bayer Cropscience Ag Verfahren zur Herstellung von substituierten 2-Alkoxycarbonyl-3-aminothiophenen
CN103360290B (zh) * 2008-02-29 2015-04-01 日产化学工业株式会社 噻吩化合物及其中间体的制造方法
WO2024079734A1 (en) 2022-10-14 2024-04-18 Adama Agan Ltd. Process for the preparation of substituted aminothiophene

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2502421A (en) * 1944-08-28 1950-04-04 Parke Davis & Co Tetrahydrothiophenes
US2502423A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 4-carbalkoxy-3-keto-2-substituted tetrahydrothiophene oximes
US2443598A (en) * 1944-12-23 1948-06-22 Parke Davis & Co 3-amino-4-carbethoxy-2-alkyl derivatives of thiophene
US2502424A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 3-acylamino-4-carboalkoxy-2-omega-ralkylthiophenes

Also Published As

Publication number Publication date
FR2365566B1 (xx) 1980-12-26
MC1156A1 (fr) 1978-04-17
ATA607477A (de) 1980-04-15
DE2737738A1 (de) 1978-03-09
BE858012A (fr) 1978-02-22
IE45470B1 (en) 1982-09-08
GB1587084A (en) 1981-03-25
NO148673B (no) 1983-08-15
NL7709246A (nl) 1978-02-27
JPS6121235B2 (xx) 1986-05-26
FI772494A (fi) 1978-02-24
FI66859C (fi) 1984-12-10
DK372177A (da) 1978-02-24
IL52792A0 (en) 1977-10-31
NO148673C (no) 1983-11-23
FR2365566A1 (fr) 1978-04-21
HU179484B (en) 1982-10-28
DK150484B (da) 1987-03-09
LU78003A1 (xx) 1978-09-14
DK150484C (da) 1987-10-05
AR222453A1 (es) 1981-05-29
AT359486B (de) 1980-11-10
JPS5340755A (en) 1978-04-13
IL52792A (en) 1981-06-29
DE2737738C2 (de) 1987-01-29
IT1143757B (it) 1986-10-22
ES461796A1 (es) 1978-12-16
NZ184981A (en) 1980-08-26
AU509956B2 (en) 1980-06-05
FI66859B (fi) 1984-08-31
IE45470L (en) 1978-02-23
AU2809277A (en) 1979-03-01
NO772917L (no) 1978-02-24

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Date Code Title Description
PUE Assignment

Owner name: F. HOFFMANN-LA ROCHE AG

PL Patent ceased