DE2737738C2 - - Google Patents

Info

Publication number
DE2737738C2
DE2737738C2 DE2737738A DE2737738A DE2737738C2 DE 2737738 C2 DE2737738 C2 DE 2737738C2 DE 2737738 A DE2737738 A DE 2737738A DE 2737738 A DE2737738 A DE 2737738A DE 2737738 C2 DE2737738 C2 DE 2737738C2
Authority
DE
Germany
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2737738A
Other versions
DE2737738A1 (de
Inventor
Pasquale Nicholas Bloomfield N.J. Us Confalone
Giacomo Belleville N.J. Us Pizzolato
Marianne Basel Ch Rouge
Milan Radoje Upper Montclair N.J. Us Uskokovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F HOFFMANN-LA ROCHE and CO AG BASEL CH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F HOFFMANN-LA ROCHE and CO AG BASEL CH filed Critical F HOFFMANN-LA ROCHE and CO AG BASEL CH
Publication of DE2737738A1 publication Critical patent/DE2737738A1/de
Application granted granted Critical
Publication of DE2737738C2 publication Critical patent/DE2737738C2/de
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19772737738 1976-08-23 1977-08-22 Derivate der 3-minothiophen-4-carbonsaeure, herstellungsverfahren und mittel cyclische verbindungen Granted DE2737738A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71685476A 1976-08-23 1976-08-23
US71685376A 1976-08-23 1976-08-23
US82052177A 1977-08-01 1977-08-01

Publications (2)

Publication Number Publication Date
DE2737738A1 DE2737738A1 (de) 1978-03-09
DE2737738C2 true DE2737738C2 (de) 1987-01-29

Family

ID=27418961

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772737738 Granted DE2737738A1 (de) 1976-08-23 1977-08-22 Derivate der 3-minothiophen-4-carbonsaeure, herstellungsverfahren und mittel cyclische verbindungen

Country Status (21)

Country Link
JP (1) JPS5340755A (de)
AR (1) AR222453A1 (de)
AT (1) AT359486B (de)
AU (1) AU509956B2 (de)
BE (1) BE858012A (de)
CH (1) CH628628A5 (de)
DE (1) DE2737738A1 (de)
DK (1) DK150484C (de)
ES (1) ES461796A1 (de)
FI (1) FI66859C (de)
FR (1) FR2365566A1 (de)
GB (1) GB1587084A (de)
HU (1) HU179484B (de)
IE (1) IE45470B1 (de)
IL (1) IL52792A (de)
IT (1) IT1143757B (de)
LU (1) LU78003A1 (de)
MC (1) MC1156A1 (de)
NL (1) NL7709246A (de)
NO (1) NO148673C (de)
NZ (1) NZ184981A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6232765Y2 (de) * 1981-02-28 1987-08-21
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
JPH08510451A (ja) 1993-05-13 1996-11-05 ネオルックス コーポレイション 異常増殖性平滑筋細胞に関連した病因の予防及び治療
WO1998046588A2 (en) 1997-04-11 1998-10-22 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
DE102004063191A1 (de) 2004-12-29 2006-07-13 Bayer Cropscience Ag Verfahren zur Herstellung von substituierten 2-Alkoxycarbonyl-3-aminothiophenen
UA104286C2 (uk) * 2008-02-29 2014-01-27 Нисан Кемикал Индастрис, Лтд. Спосіб одержання тіофенової сполуки та її проміжних сполук (варіанти)
WO2024079734A1 (en) 2022-10-14 2024-04-18 Adama Agan Ltd. Process for the preparation of substituted aminothiophene

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2502421A (en) * 1944-08-28 1950-04-04 Parke Davis & Co Tetrahydrothiophenes
US2502423A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 4-carbalkoxy-3-keto-2-substituted tetrahydrothiophene oximes
US2443598A (en) * 1944-12-23 1948-06-22 Parke Davis & Co 3-amino-4-carbethoxy-2-alkyl derivatives of thiophene
US2502424A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 3-acylamino-4-carboalkoxy-2-omega-ralkylthiophenes

Also Published As

Publication number Publication date
FR2365566B1 (de) 1980-12-26
NO148673C (no) 1983-11-23
DE2737738A1 (de) 1978-03-09
FI772494A (fi) 1978-02-24
DK372177A (da) 1978-02-24
HU179484B (en) 1982-10-28
DK150484C (da) 1987-10-05
FI66859C (fi) 1984-12-10
IL52792A0 (en) 1977-10-31
LU78003A1 (de) 1978-09-14
MC1156A1 (fr) 1978-04-17
GB1587084A (en) 1981-03-25
ATA607477A (de) 1980-04-15
JPS6121235B2 (de) 1986-05-26
BE858012A (fr) 1978-02-22
FR2365566A1 (fr) 1978-04-21
NZ184981A (en) 1980-08-26
NO148673B (no) 1983-08-15
CH628628A5 (en) 1982-03-15
FI66859B (fi) 1984-08-31
IL52792A (en) 1981-06-29
ES461796A1 (es) 1978-12-16
AT359486B (de) 1980-11-10
IE45470L (en) 1978-02-23
AU509956B2 (en) 1980-06-05
DK150484B (da) 1987-03-09
AU2809277A (en) 1979-03-01
NL7709246A (nl) 1978-02-27
AR222453A1 (es) 1981-05-29
IE45470B1 (en) 1982-09-08
JPS5340755A (en) 1978-04-13
IT1143757B (it) 1986-10-22
NO772917L (no) 1978-02-24

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Legal Events

Date Code Title Description
OB Request for examination as to novelty
OC Search report available
8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: LEDERER, F., DIPL.-CHEM. DR., PAT.-ANW., 8000 MUEN

D2 Grant after examination
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: F. HOFFMANN-LA ROCHE AG, BASEL, CH

8328 Change in the person/name/address of the agent

Free format text: LEDERER, F., DIPL.-CHEM. DR., 8000 MUENCHEN RIEDERER FRHR. VON PAAR ZU SCHOENAU, A., DIPL.-ING., PAT.-ANWAELTE, 8300 LANDSHUT

8339 Ceased/non-payment of the annual fee