FR2365566A1 - Nouveaux derives du thiophene utiles comme medicaments - Google Patents

Nouveaux derives du thiophene utiles comme medicaments

Info

Publication number
FR2365566A1
FR2365566A1 FR7725379A FR7725379A FR2365566A1 FR 2365566 A1 FR2365566 A1 FR 2365566A1 FR 7725379 A FR7725379 A FR 7725379A FR 7725379 A FR7725379 A FR 7725379A FR 2365566 A1 FR2365566 A1 FR 2365566A1
Authority
FR
France
Prior art keywords
medicinal products
derivatives useful
thiophene derivatives
new thiophene
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7725379A
Other languages
English (en)
Other versions
FR2365566B1 (fr
Inventor
Pasquale Nicholas Confalone
Giacomo Pizzolato
Marianne Rouge
Milan Radoje Uskokovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2365566A1 publication Critical patent/FR2365566A1/fr
Application granted granted Critical
Publication of FR2365566B1 publication Critical patent/FR2365566B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Abstract

La présente invention concerne des composés chimiques nouveaux et un procédé pour leur préparation. Il s'agit de composés de formule :
FR7725379A 1976-08-23 1977-08-19 Nouveaux derives du thiophene utiles comme medicaments Granted FR2365566A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71685476A 1976-08-23 1976-08-23
US71685376A 1976-08-23 1976-08-23
US82052177A 1977-08-01 1977-08-01

Publications (2)

Publication Number Publication Date
FR2365566A1 true FR2365566A1 (fr) 1978-04-21
FR2365566B1 FR2365566B1 (fr) 1980-12-26

Family

ID=27418961

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7725379A Granted FR2365566A1 (fr) 1976-08-23 1977-08-19 Nouveaux derives du thiophene utiles comme medicaments

Country Status (21)

Country Link
JP (1) JPS5340755A (fr)
AR (1) AR222453A1 (fr)
AT (1) AT359486B (fr)
AU (1) AU509956B2 (fr)
BE (1) BE858012A (fr)
CH (1) CH628628A5 (fr)
DE (1) DE2737738A1 (fr)
DK (1) DK150484C (fr)
ES (1) ES461796A1 (fr)
FI (1) FI66859C (fr)
FR (1) FR2365566A1 (fr)
GB (1) GB1587084A (fr)
HU (1) HU179484B (fr)
IE (1) IE45470B1 (fr)
IL (1) IL52792A (fr)
IT (1) IT1143757B (fr)
LU (1) LU78003A1 (fr)
MC (1) MC1156A1 (fr)
NL (1) NL7709246A (fr)
NO (1) NO148673C (fr)
NZ (1) NZ184981A (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6232765Y2 (fr) * 1981-02-28 1987-08-21
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
ATE406909T1 (de) 1993-05-13 2008-09-15 Poniard Pharmaceuticals Inc Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind
AU6959898A (en) * 1997-04-11 1998-11-11 David J. Grainger Compounds and therapies for the prevention of vascular and non-vascular pathol ogies
DE102004063191A1 (de) 2004-12-29 2006-07-13 Bayer Cropscience Ag Verfahren zur Herstellung von substituierten 2-Alkoxycarbonyl-3-aminothiophenen
CN101959875B (zh) * 2008-02-29 2013-10-16 日产化学工业株式会社 噻吩化合物及其中间体的制造方法
WO2024079734A1 (fr) 2022-10-14 2024-04-18 Adama Agan Ltd. Procédé de préparation d'aminothiophène substitué

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2443598A (en) * 1944-12-23 1948-06-22 Parke Davis & Co 3-amino-4-carbethoxy-2-alkyl derivatives of thiophene
US2502423A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 4-carbalkoxy-3-keto-2-substituted tetrahydrothiophene oximes
US2502421A (en) * 1944-08-28 1950-04-04 Parke Davis & Co Tetrahydrothiophenes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2502424A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 3-acylamino-4-carboalkoxy-2-omega-ralkylthiophenes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2502421A (en) * 1944-08-28 1950-04-04 Parke Davis & Co Tetrahydrothiophenes
US2443598A (en) * 1944-12-23 1948-06-22 Parke Davis & Co 3-amino-4-carbethoxy-2-alkyl derivatives of thiophene
US2502423A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 4-carbalkoxy-3-keto-2-substituted tetrahydrothiophene oximes

Also Published As

Publication number Publication date
AU2809277A (en) 1979-03-01
AU509956B2 (en) 1980-06-05
HU179484B (en) 1982-10-28
FI66859C (fi) 1984-12-10
NO148673B (no) 1983-08-15
IL52792A (en) 1981-06-29
DE2737738C2 (fr) 1987-01-29
AT359486B (de) 1980-11-10
IE45470B1 (en) 1982-09-08
FI66859B (fi) 1984-08-31
GB1587084A (en) 1981-03-25
MC1156A1 (fr) 1978-04-17
DK150484C (da) 1987-10-05
DE2737738A1 (de) 1978-03-09
NO772917L (no) 1978-02-24
LU78003A1 (fr) 1978-09-14
NL7709246A (nl) 1978-02-27
ES461796A1 (es) 1978-12-16
IL52792A0 (en) 1977-10-31
AR222453A1 (es) 1981-05-29
NO148673C (no) 1983-11-23
FI772494A (fi) 1978-02-24
DK150484B (da) 1987-03-09
CH628628A5 (en) 1982-03-15
IE45470L (en) 1978-02-23
ATA607477A (de) 1980-04-15
DK372177A (da) 1978-02-24
JPS6121235B2 (fr) 1986-05-26
FR2365566B1 (fr) 1980-12-26
JPS5340755A (en) 1978-04-13
NZ184981A (en) 1980-08-26
IT1143757B (it) 1986-10-22
BE858012A (fr) 1978-02-22

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse