FR2386545A1 - L'acide 3-(2-aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylique utile comme medicament - Google Patents

L'acide 3-(2-aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylique utile comme medicament

Info

Publication number
FR2386545A1
FR2386545A1 FR7810238A FR7810238A FR2386545A1 FR 2386545 A1 FR2386545 A1 FR 2386545A1 FR 7810238 A FR7810238 A FR 7810238A FR 7810238 A FR7810238 A FR 7810238A FR 2386545 A1 FR2386545 A1 FR 2386545A1
Authority
FR
France
Prior art keywords
aminoethylthio
azabicyclo
hept
oxo
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7810238A
Other languages
English (en)
Other versions
FR2386545B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2386545A1 publication Critical patent/FR2386545A1/fr
Application granted granted Critical
Publication of FR2386545B1 publication Critical patent/FR2386545B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La présente invention concerne des composés chimiques nouveaux et leur préparation. Il s'agit de l'acide 3-(2-aminoéthylthio)-6-éthyl-7-oxo-1-azabicyclo 3.2.0)-hept-2-ène-2-carboxylique de formule :
FR7810238A 1977-04-08 1978-04-06 L'acide 3-(2-aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylique utile comme medicament Granted FR2386545A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78581177A 1977-04-08 1977-04-08
US86123077A 1977-12-16 1977-12-16

Publications (2)

Publication Number Publication Date
FR2386545A1 true FR2386545A1 (fr) 1978-11-03
FR2386545B1 FR2386545B1 (fr) 1980-08-01

Family

ID=27120448

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7810238A Granted FR2386545A1 (fr) 1977-04-08 1978-04-06 L'acide 3-(2-aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylique utile comme medicament

Country Status (11)

Country Link
JP (1) JPS53127491A (fr)
CH (1) CH640236A5 (fr)
DE (1) DE2815157A1 (fr)
DK (1) DK123578A (fr)
FR (1) FR2386545A1 (fr)
GB (1) GB1595267A (fr)
IE (1) IE47043B1 (fr)
IT (1) IT1102456B (fr)
LU (1) LU79403A1 (fr)
NL (1) NL7802826A (fr)
SE (1) SE7803173L (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408608A1 (fr) * 1977-03-31 1979-06-08 Sanraku Ocean Co Nouvel antibiotique denomme ps-5 et ses derives doues d'activite inhibitrice de la b-lactamase et leur procede de preparation

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5473788A (en) * 1977-11-17 1979-06-13 Sanraku Inc Antibiotic n-desacetyl ps-5
EP0005349A1 (fr) * 1978-05-06 1979-11-14 Beecham Group Plc Alkylcarbapénèmes, leur préparation, compositions pharmaceutiques les contenant et les intermédiaires
JPS5572191A (en) * 1978-11-22 1980-05-30 Sanraku Inc Antibiotic n-desacetyl ps-5
JPS55136282A (en) * 1979-04-06 1980-10-23 Shionogi & Co Ltd Novel antibiotic pa-31088-4
US4235922A (en) * 1979-06-15 1980-11-25 Merck & Co., Inc. 3-(2-Aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo [3.2.0]hept-2-ene-2-carboxylic acid
EP0055990B1 (fr) * 1979-08-10 1986-06-11 Beecham Group Plc Antibiotiques bêta-lactame, leur préparation et application
JPS5683489A (en) * 1979-12-12 1981-07-08 Shionogi & Co Ltd New antibiotic pa-39504-x1 and it preparation
JPS5764693A (en) * 1980-10-07 1982-04-19 Kowa Co Novel carbapenem compound and its preparation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408608A1 (fr) * 1977-03-31 1979-06-08 Sanraku Ocean Co Nouvel antibiotique denomme ps-5 et ses derives doues d'activite inhibitrice de la b-lactamase et leur procede de preparation

Also Published As

Publication number Publication date
CH640236A5 (en) 1983-12-30
IE47043B1 (en) 1983-12-14
DE2815157A1 (de) 1978-10-19
NL7802826A (nl) 1978-10-10
IT7848747A0 (it) 1978-04-05
IE780631L (en) 1978-10-08
DK123578A (da) 1978-10-09
LU79403A1 (fr) 1978-11-27
GB1595267A (en) 1981-08-12
FR2386545B1 (fr) 1980-08-01
JPS53127491A (en) 1978-11-07
SE7803173L (sv) 1978-10-09
IT1102456B (it) 1985-10-07

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Legal Events

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ST Notification of lapse