IL52792A - 5-substituted-4-amino-thiophene-3-carboxylic acid derivatives,their preparation and antiobesity and blood lipid lowering pharmaceutical compositions containing them - Google Patents
5-substituted-4-amino-thiophene-3-carboxylic acid derivatives,their preparation and antiobesity and blood lipid lowering pharmaceutical compositions containing themInfo
- Publication number
- IL52792A IL52792A IL52792A IL5279277A IL52792A IL 52792 A IL52792 A IL 52792A IL 52792 A IL52792 A IL 52792A IL 5279277 A IL5279277 A IL 5279277A IL 52792 A IL52792 A IL 52792A
- Authority
- IL
- Israel
- Prior art keywords
- antiobesity
- thiophene
- amino
- substituted
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71685376A | 1976-08-23 | 1976-08-23 | |
US71685476A | 1976-08-23 | 1976-08-23 | |
US82052177A | 1977-08-01 | 1977-08-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL52792A0 IL52792A0 (en) | 1977-10-31 |
IL52792A true IL52792A (en) | 1981-06-29 |
Family
ID=27418961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL52792A IL52792A (en) | 1976-08-23 | 1977-08-22 | 5-substituted-4-amino-thiophene-3-carboxylic acid derivatives,their preparation and antiobesity and blood lipid lowering pharmaceutical compositions containing them |
Country Status (21)
Country | Link |
---|---|
JP (1) | JPS5340755A (xx) |
AR (1) | AR222453A1 (xx) |
AT (1) | AT359486B (xx) |
AU (1) | AU509956B2 (xx) |
BE (1) | BE858012A (xx) |
CH (1) | CH628628A5 (xx) |
DE (1) | DE2737738C2 (xx) |
DK (1) | DK150484C (xx) |
ES (1) | ES461796A1 (xx) |
FI (1) | FI66859C (xx) |
FR (1) | FR2365566A1 (xx) |
GB (1) | GB1587084A (xx) |
HU (1) | HU179484B (xx) |
IE (1) | IE45470B1 (xx) |
IL (1) | IL52792A (xx) |
IT (1) | IT1143757B (xx) |
LU (1) | LU78003A1 (xx) |
MC (1) | MC1156A1 (xx) |
NL (1) | NL7709246A (xx) |
NO (1) | NO148673C (xx) |
NZ (1) | NZ184981A (xx) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6232765Y2 (xx) * | 1981-02-28 | 1987-08-21 | ||
US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US5847007A (en) | 1993-05-13 | 1998-12-08 | Neorx Corporation | Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
AU6959898A (en) | 1997-04-11 | 1998-11-11 | David J. Grainger | Compounds and therapies for the prevention of vascular and non-vascular pathol ogies |
DE102004063191A1 (de) | 2004-12-29 | 2006-07-13 | Bayer Cropscience Ag | Verfahren zur Herstellung von substituierten 2-Alkoxycarbonyl-3-aminothiophenen |
TWI476187B (zh) * | 2008-02-29 | 2015-03-11 | Nissan Chemical Ind Ltd | Thiophene compounds and intermediates thereof |
WO2024079734A1 (en) | 2022-10-14 | 2024-04-18 | Adama Agan Ltd. | Process for the preparation of substituted aminothiophene |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2502421A (en) * | 1944-08-28 | 1950-04-04 | Parke Davis & Co | Tetrahydrothiophenes |
US2443598A (en) * | 1944-12-23 | 1948-06-22 | Parke Davis & Co | 3-amino-4-carbethoxy-2-alkyl derivatives of thiophene |
US2502423A (en) * | 1944-12-23 | 1950-04-04 | Parke Davis & Co | 4-carbalkoxy-3-keto-2-substituted tetrahydrothiophene oximes |
US2502424A (en) * | 1944-12-23 | 1950-04-04 | Parke Davis & Co | 3-acylamino-4-carboalkoxy-2-omega-ralkylthiophenes |
-
1977
- 1977-08-03 CH CH954377A patent/CH628628A5/de not_active IP Right Cessation
- 1977-08-19 FR FR7725379A patent/FR2365566A1/fr active Granted
- 1977-08-22 BE BE180354A patent/BE858012A/xx not_active IP Right Cessation
- 1977-08-22 NO NO772917A patent/NO148673C/no unknown
- 1977-08-22 NZ NZ184981A patent/NZ184981A/xx unknown
- 1977-08-22 JP JP9963877A patent/JPS5340755A/ja active Granted
- 1977-08-22 MC MC771256A patent/MC1156A1/xx unknown
- 1977-08-22 NL NL7709246A patent/NL7709246A/xx not_active Application Discontinuation
- 1977-08-22 HU HU77HO2009A patent/HU179484B/hu not_active IP Right Cessation
- 1977-08-22 AT AT607477A patent/AT359486B/de not_active IP Right Cessation
- 1977-08-22 GB GB35098/77A patent/GB1587084A/en not_active Expired
- 1977-08-22 IT IT26845/77A patent/IT1143757B/it active
- 1977-08-22 AR AR268888A patent/AR222453A1/es active
- 1977-08-22 IL IL52792A patent/IL52792A/xx unknown
- 1977-08-22 DK DK372177A patent/DK150484C/da active
- 1977-08-22 DE DE2737738A patent/DE2737738C2/de not_active Expired
- 1977-08-22 FI FI772494A patent/FI66859C/fi not_active IP Right Cessation
- 1977-08-22 IE IE1751/77A patent/IE45470B1/en unknown
- 1977-08-22 LU LU78003A patent/LU78003A1/xx unknown
- 1977-08-22 AU AU28092/77A patent/AU509956B2/en not_active Expired
- 1977-08-22 ES ES461796A patent/ES461796A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
AT359486B (de) | 1980-11-10 |
FI772494A (fi) | 1978-02-24 |
DE2737738C2 (de) | 1987-01-29 |
IE45470L (en) | 1978-02-23 |
IT1143757B (it) | 1986-10-22 |
DE2737738A1 (de) | 1978-03-09 |
FI66859B (fi) | 1984-08-31 |
JPS6121235B2 (xx) | 1986-05-26 |
JPS5340755A (en) | 1978-04-13 |
IL52792A0 (en) | 1977-10-31 |
FI66859C (fi) | 1984-12-10 |
NO148673B (no) | 1983-08-15 |
DK150484C (da) | 1987-10-05 |
NZ184981A (en) | 1980-08-26 |
DK150484B (da) | 1987-03-09 |
GB1587084A (en) | 1981-03-25 |
LU78003A1 (xx) | 1978-09-14 |
ES461796A1 (es) | 1978-12-16 |
BE858012A (fr) | 1978-02-22 |
FR2365566A1 (fr) | 1978-04-21 |
HU179484B (en) | 1982-10-28 |
NO148673C (no) | 1983-11-23 |
AR222453A1 (es) | 1981-05-29 |
AU509956B2 (en) | 1980-06-05 |
NL7709246A (nl) | 1978-02-27 |
MC1156A1 (fr) | 1978-04-17 |
FR2365566B1 (xx) | 1980-12-26 |
DK372177A (da) | 1978-02-24 |
NO772917L (no) | 1978-02-24 |
IE45470B1 (en) | 1982-09-08 |
AU2809277A (en) | 1979-03-01 |
ATA607477A (de) | 1980-04-15 |
CH628628A5 (en) | 1982-03-15 |
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