GB1587084A - Thiophene derivatives - Google Patents
Thiophene derivatives Download PDFInfo
- Publication number
- GB1587084A GB1587084A GB35098/77A GB3509877A GB1587084A GB 1587084 A GB1587084 A GB 1587084A GB 35098/77 A GB35098/77 A GB 35098/77A GB 3509877 A GB3509877 A GB 3509877A GB 1587084 A GB1587084 A GB 1587084A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amino
- group
- formula
- compound
- hydrochloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71685376A | 1976-08-23 | 1976-08-23 | |
US71685476A | 1976-08-23 | 1976-08-23 | |
US82052177A | 1977-08-01 | 1977-08-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1587084A true GB1587084A (en) | 1981-03-25 |
Family
ID=27418961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB35098/77A Expired GB1587084A (en) | 1976-08-23 | 1977-08-22 | Thiophene derivatives |
Country Status (21)
Country | Link |
---|---|
JP (1) | JPS5340755A (fr) |
AR (1) | AR222453A1 (fr) |
AT (1) | AT359486B (fr) |
AU (1) | AU509956B2 (fr) |
BE (1) | BE858012A (fr) |
CH (1) | CH628628A5 (fr) |
DE (1) | DE2737738C2 (fr) |
DK (1) | DK150484C (fr) |
ES (1) | ES461796A1 (fr) |
FI (1) | FI66859C (fr) |
FR (1) | FR2365566A1 (fr) |
GB (1) | GB1587084A (fr) |
HU (1) | HU179484B (fr) |
IE (1) | IE45470B1 (fr) |
IL (1) | IL52792A (fr) |
IT (1) | IT1143757B (fr) |
LU (1) | LU78003A1 (fr) |
MC (1) | MC1156A1 (fr) |
NL (1) | NL7709246A (fr) |
NO (1) | NO148673C (fr) |
NZ (1) | NZ184981A (fr) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998046588A2 (fr) * | 1997-04-11 | 1998-10-22 | Neorx Corporation | Composes et therapies destines a la prevention d'affections vasculaires ou non vasculaires |
US6166090A (en) | 1993-05-13 | 2000-12-26 | Neorx Corporation | Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
CN101959875A (zh) * | 2008-02-29 | 2011-01-26 | 日产化学工业株式会社 | 噻吩化合物及其中间体的制造方法 |
US7923571B2 (en) | 2004-12-29 | 2011-04-12 | Bayer Cropscience Ag | Process for preparing substituted 2-alkoxycarbonyl-3-aminothiophenes |
US8067022B2 (en) | 1992-09-25 | 2011-11-29 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
US8097642B2 (en) | 1995-02-15 | 2012-01-17 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
WO2024079734A1 (fr) | 2022-10-14 | 2024-04-18 | Adama Agan Ltd. | Procédé de préparation d'aminothiophène substitué |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6232765Y2 (fr) * | 1981-02-28 | 1987-08-21 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2502421A (en) * | 1944-08-28 | 1950-04-04 | Parke Davis & Co | Tetrahydrothiophenes |
US2443598A (en) * | 1944-12-23 | 1948-06-22 | Parke Davis & Co | 3-amino-4-carbethoxy-2-alkyl derivatives of thiophene |
US2502424A (en) * | 1944-12-23 | 1950-04-04 | Parke Davis & Co | 3-acylamino-4-carboalkoxy-2-omega-ralkylthiophenes |
US2502423A (en) * | 1944-12-23 | 1950-04-04 | Parke Davis & Co | 4-carbalkoxy-3-keto-2-substituted tetrahydrothiophene oximes |
-
1977
- 1977-08-03 CH CH954377A patent/CH628628A5/de not_active IP Right Cessation
- 1977-08-19 FR FR7725379A patent/FR2365566A1/fr active Granted
- 1977-08-22 NZ NZ184981A patent/NZ184981A/xx unknown
- 1977-08-22 LU LU78003A patent/LU78003A1/xx unknown
- 1977-08-22 AU AU28092/77A patent/AU509956B2/en not_active Expired
- 1977-08-22 JP JP9963877A patent/JPS5340755A/ja active Granted
- 1977-08-22 IL IL52792A patent/IL52792A/xx unknown
- 1977-08-22 HU HU77HO2009A patent/HU179484B/hu not_active IP Right Cessation
- 1977-08-22 IE IE1751/77A patent/IE45470B1/en unknown
- 1977-08-22 NL NL7709246A patent/NL7709246A/xx not_active Application Discontinuation
- 1977-08-22 GB GB35098/77A patent/GB1587084A/en not_active Expired
- 1977-08-22 BE BE180354A patent/BE858012A/fr not_active IP Right Cessation
- 1977-08-22 FI FI772494A patent/FI66859C/fi not_active IP Right Cessation
- 1977-08-22 ES ES461796A patent/ES461796A1/es not_active Expired
- 1977-08-22 IT IT26845/77A patent/IT1143757B/it active
- 1977-08-22 MC MC771256A patent/MC1156A1/fr unknown
- 1977-08-22 DK DK372177A patent/DK150484C/da active
- 1977-08-22 AR AR268888A patent/AR222453A1/es active
- 1977-08-22 AT AT607477A patent/AT359486B/de not_active IP Right Cessation
- 1977-08-22 DE DE2737738A patent/DE2737738C2/de not_active Expired
- 1977-08-22 NO NO772917A patent/NO148673C/no unknown
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8067022B2 (en) | 1992-09-25 | 2011-11-29 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
US6569441B2 (en) | 1993-01-28 | 2003-05-27 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6166090A (en) | 1993-05-13 | 2000-12-26 | Neorx Corporation | Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US8097642B2 (en) | 1995-02-15 | 2012-01-17 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
US8158670B2 (en) | 1995-02-15 | 2012-04-17 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
WO1998046588A3 (fr) * | 1997-04-11 | 1999-01-07 | Neorx Corp | Composes et therapies destines a la prevention d'affections vasculaires ou non vasculaires |
US6734208B2 (en) | 1997-04-11 | 2004-05-11 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
WO1998046588A2 (fr) * | 1997-04-11 | 1998-10-22 | Neorx Corporation | Composes et therapies destines a la prevention d'affections vasculaires ou non vasculaires |
US7923571B2 (en) | 2004-12-29 | 2011-04-12 | Bayer Cropscience Ag | Process for preparing substituted 2-alkoxycarbonyl-3-aminothiophenes |
CN101959875A (zh) * | 2008-02-29 | 2011-01-26 | 日产化学工业株式会社 | 噻吩化合物及其中间体的制造方法 |
CN101959875B (zh) * | 2008-02-29 | 2013-10-16 | 日产化学工业株式会社 | 噻吩化合物及其中间体的制造方法 |
CN103360290A (zh) * | 2008-02-29 | 2013-10-23 | 日产化学工业株式会社 | 噻吩化合物及其中间体的制造方法 |
CN103435593B (zh) * | 2008-02-29 | 2015-01-28 | 日产化学工业株式会社 | 噻吩化合物及其中间体的制造方法 |
CN103360290B (zh) * | 2008-02-29 | 2015-04-01 | 日产化学工业株式会社 | 噻吩化合物及其中间体的制造方法 |
WO2024079734A1 (fr) | 2022-10-14 | 2024-04-18 | Adama Agan Ltd. | Procédé de préparation d'aminothiophène substitué |
Also Published As
Publication number | Publication date |
---|---|
NO148673C (no) | 1983-11-23 |
FI66859B (fi) | 1984-08-31 |
BE858012A (fr) | 1978-02-22 |
NO772917L (no) | 1978-02-24 |
AU2809277A (en) | 1979-03-01 |
AR222453A1 (es) | 1981-05-29 |
FR2365566A1 (fr) | 1978-04-21 |
FI66859C (fi) | 1984-12-10 |
NL7709246A (nl) | 1978-02-27 |
DK372177A (da) | 1978-02-24 |
JPS5340755A (en) | 1978-04-13 |
DE2737738A1 (de) | 1978-03-09 |
MC1156A1 (fr) | 1978-04-17 |
IE45470L (en) | 1978-02-23 |
HU179484B (en) | 1982-10-28 |
DE2737738C2 (de) | 1987-01-29 |
IL52792A0 (en) | 1977-10-31 |
NZ184981A (en) | 1980-08-26 |
DK150484C (da) | 1987-10-05 |
IT1143757B (it) | 1986-10-22 |
NO148673B (no) | 1983-08-15 |
JPS6121235B2 (fr) | 1986-05-26 |
CH628628A5 (en) | 1982-03-15 |
AT359486B (de) | 1980-11-10 |
LU78003A1 (fr) | 1978-09-14 |
IL52792A (en) | 1981-06-29 |
IE45470B1 (en) | 1982-09-08 |
ES461796A1 (es) | 1978-12-16 |
FR2365566B1 (fr) | 1980-12-26 |
AU509956B2 (en) | 1980-06-05 |
FI772494A (fi) | 1978-02-24 |
ATA607477A (de) | 1980-04-15 |
DK150484B (da) | 1987-03-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
PCNP | Patent ceased through non-payment of renewal fee |