HU179484B - Process for preparing 3-amino-thiophene-4-carboxylic acid derivatives - Google Patents

Process for preparing 3-amino-thiophene-4-carboxylic acid derivatives

Info

Publication number
HU179484B
HU179484B HU77HO2009A HUHO002009A HU179484B HU 179484 B HU179484 B HU 179484B HU 77HO2009 A HU77HO2009 A HU 77HO2009A HU HO002009 A HUHO002009 A HU HO002009A HU 179484 B HU179484 B HU 179484B
Authority
HU
Hungary
Prior art keywords
thiophene
amino
preparing
carboxylic acid
acid derivatives
Prior art date
Application number
HU77HO2009A
Other languages
English (en)
Hungarian (hu)
Inventor
Pasquale N Confalone
Giacomo Pizzoloto
Marianne Rouge
Milan R Uskovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HU179484B publication Critical patent/HU179484B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU77HO2009A 1976-08-23 1977-08-22 Process for preparing 3-amino-thiophene-4-carboxylic acid derivatives HU179484B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71685476A 1976-08-23 1976-08-23
US71685376A 1976-08-23 1976-08-23
US82052177A 1977-08-01 1977-08-01

Publications (1)

Publication Number Publication Date
HU179484B true HU179484B (en) 1982-10-28

Family

ID=27418961

Family Applications (1)

Application Number Title Priority Date Filing Date
HU77HO2009A HU179484B (en) 1976-08-23 1977-08-22 Process for preparing 3-amino-thiophene-4-carboxylic acid derivatives

Country Status (21)

Country Link
JP (1) JPS5340755A (de)
AR (1) AR222453A1 (de)
AT (1) AT359486B (de)
AU (1) AU509956B2 (de)
BE (1) BE858012A (de)
CH (1) CH628628A5 (de)
DE (1) DE2737738A1 (de)
DK (1) DK150484C (de)
ES (1) ES461796A1 (de)
FI (1) FI66859C (de)
FR (1) FR2365566A1 (de)
GB (1) GB1587084A (de)
HU (1) HU179484B (de)
IE (1) IE45470B1 (de)
IL (1) IL52792A (de)
IT (1) IT1143757B (de)
LU (1) LU78003A1 (de)
MC (1) MC1156A1 (de)
NL (1) NL7709246A (de)
NO (1) NO148673C (de)
NZ (1) NZ184981A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6232765Y2 (de) * 1981-02-28 1987-08-21
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
JPH08510451A (ja) 1993-05-13 1996-11-05 ネオルックス コーポレイション 異常増殖性平滑筋細胞に関連した病因の予防及び治療
WO1998046588A2 (en) 1997-04-11 1998-10-22 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
DE102004063191A1 (de) 2004-12-29 2006-07-13 Bayer Cropscience Ag Verfahren zur Herstellung von substituierten 2-Alkoxycarbonyl-3-aminothiophenen
UA104286C2 (uk) * 2008-02-29 2014-01-27 Нисан Кемикал Индастрис, Лтд. Спосіб одержання тіофенової сполуки та її проміжних сполук (варіанти)
WO2024079734A1 (en) 2022-10-14 2024-04-18 Adama Agan Ltd. Process for the preparation of substituted aminothiophene

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2502421A (en) * 1944-08-28 1950-04-04 Parke Davis & Co Tetrahydrothiophenes
US2502423A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 4-carbalkoxy-3-keto-2-substituted tetrahydrothiophene oximes
US2443598A (en) * 1944-12-23 1948-06-22 Parke Davis & Co 3-amino-4-carbethoxy-2-alkyl derivatives of thiophene
US2502424A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 3-acylamino-4-carboalkoxy-2-omega-ralkylthiophenes

Also Published As

Publication number Publication date
FR2365566B1 (de) 1980-12-26
NO148673C (no) 1983-11-23
DE2737738A1 (de) 1978-03-09
FI772494A (fi) 1978-02-24
DK372177A (da) 1978-02-24
DK150484C (da) 1987-10-05
FI66859C (fi) 1984-12-10
IL52792A0 (en) 1977-10-31
LU78003A1 (de) 1978-09-14
DE2737738C2 (de) 1987-01-29
MC1156A1 (fr) 1978-04-17
GB1587084A (en) 1981-03-25
ATA607477A (de) 1980-04-15
JPS6121235B2 (de) 1986-05-26
BE858012A (fr) 1978-02-22
FR2365566A1 (fr) 1978-04-21
NZ184981A (en) 1980-08-26
NO148673B (no) 1983-08-15
CH628628A5 (en) 1982-03-15
FI66859B (fi) 1984-08-31
IL52792A (en) 1981-06-29
ES461796A1 (es) 1978-12-16
AT359486B (de) 1980-11-10
IE45470L (en) 1978-02-23
AU509956B2 (en) 1980-06-05
DK150484B (da) 1987-03-09
AU2809277A (en) 1979-03-01
NL7709246A (nl) 1978-02-27
AR222453A1 (es) 1981-05-29
IE45470B1 (en) 1982-09-08
JPS5340755A (en) 1978-04-13
IT1143757B (it) 1986-10-22
NO772917L (no) 1978-02-24

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee