FI66859C - Foerfarande foer framstaellning av 4-aminotiofen-3-karboxylsyraderivat med fysiologisk verkan - Google Patents

Foerfarande foer framstaellning av 4-aminotiofen-3-karboxylsyraderivat med fysiologisk verkan Download PDF

Info

Publication number
FI66859C
FI66859C FI772494A FI772494A FI66859C FI 66859 C FI66859 C FI 66859C FI 772494 A FI772494 A FI 772494A FI 772494 A FI772494 A FI 772494A FI 66859 C FI66859 C FI 66859C
Authority
FI
Finland
Prior art keywords
formula
solution
ethyl
carbomethoxy
methanol
Prior art date
Application number
FI772494A
Other languages
English (en)
Finnish (fi)
Other versions
FI772494A (fi
FI66859B (fi
Inventor
Pasquale Nicholas Confalone
Giacomo Pizzolato
Milan Radoje Uskokovic
Marianne Rouge
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI772494A publication Critical patent/FI772494A/fi
Application granted granted Critical
Publication of FI66859B publication Critical patent/FI66859B/fi
Publication of FI66859C publication Critical patent/FI66859C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI772494A 1976-08-23 1977-08-22 Foerfarande foer framstaellning av 4-aminotiofen-3-karboxylsyraderivat med fysiologisk verkan FI66859C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US71685476A 1976-08-23 1976-08-23
US71685376A 1976-08-23 1976-08-23
US71685476 1976-08-23
US71685376 1976-08-23
US82052177A 1977-08-01 1977-08-01
US82052177 1977-08-01

Publications (3)

Publication Number Publication Date
FI772494A FI772494A (fi) 1978-02-24
FI66859B FI66859B (fi) 1984-08-31
FI66859C true FI66859C (fi) 1984-12-10

Family

ID=27418961

Family Applications (1)

Application Number Title Priority Date Filing Date
FI772494A FI66859C (fi) 1976-08-23 1977-08-22 Foerfarande foer framstaellning av 4-aminotiofen-3-karboxylsyraderivat med fysiologisk verkan

Country Status (21)

Country Link
JP (1) JPS5340755A (de)
AR (1) AR222453A1 (de)
AT (1) AT359486B (de)
AU (1) AU509956B2 (de)
BE (1) BE858012A (de)
CH (1) CH628628A5 (de)
DE (1) DE2737738A1 (de)
DK (1) DK150484C (de)
ES (1) ES461796A1 (de)
FI (1) FI66859C (de)
FR (1) FR2365566A1 (de)
GB (1) GB1587084A (de)
HU (1) HU179484B (de)
IE (1) IE45470B1 (de)
IL (1) IL52792A (de)
IT (1) IT1143757B (de)
LU (1) LU78003A1 (de)
MC (1) MC1156A1 (de)
NL (1) NL7709246A (de)
NO (1) NO148673C (de)
NZ (1) NZ184981A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6232765Y2 (de) * 1981-02-28 1987-08-21
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
JPH08510451A (ja) 1993-05-13 1996-11-05 ネオルックス コーポレイション 異常増殖性平滑筋細胞に関連した病因の予防及び治療
WO1998046588A2 (en) 1997-04-11 1998-10-22 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
DE102004063191A1 (de) 2004-12-29 2006-07-13 Bayer Cropscience Ag Verfahren zur Herstellung von substituierten 2-Alkoxycarbonyl-3-aminothiophenen
UA104286C2 (uk) * 2008-02-29 2014-01-27 Нисан Кемикал Индастрис, Лтд. Спосіб одержання тіофенової сполуки та її проміжних сполук (варіанти)
WO2024079734A1 (en) 2022-10-14 2024-04-18 Adama Agan Ltd. Process for the preparation of substituted aminothiophene

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2502421A (en) * 1944-08-28 1950-04-04 Parke Davis & Co Tetrahydrothiophenes
US2502423A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 4-carbalkoxy-3-keto-2-substituted tetrahydrothiophene oximes
US2443598A (en) * 1944-12-23 1948-06-22 Parke Davis & Co 3-amino-4-carbethoxy-2-alkyl derivatives of thiophene
US2502424A (en) * 1944-12-23 1950-04-04 Parke Davis & Co 3-acylamino-4-carboalkoxy-2-omega-ralkylthiophenes

Also Published As

Publication number Publication date
FR2365566B1 (de) 1980-12-26
NO148673C (no) 1983-11-23
DE2737738A1 (de) 1978-03-09
FI772494A (fi) 1978-02-24
DK372177A (da) 1978-02-24
HU179484B (en) 1982-10-28
DK150484C (da) 1987-10-05
IL52792A0 (en) 1977-10-31
LU78003A1 (de) 1978-09-14
DE2737738C2 (de) 1987-01-29
MC1156A1 (fr) 1978-04-17
GB1587084A (en) 1981-03-25
ATA607477A (de) 1980-04-15
JPS6121235B2 (de) 1986-05-26
BE858012A (fr) 1978-02-22
FR2365566A1 (fr) 1978-04-21
NZ184981A (en) 1980-08-26
NO148673B (no) 1983-08-15
CH628628A5 (en) 1982-03-15
FI66859B (fi) 1984-08-31
IL52792A (en) 1981-06-29
ES461796A1 (es) 1978-12-16
AT359486B (de) 1980-11-10
IE45470L (en) 1978-02-23
AU509956B2 (en) 1980-06-05
DK150484B (da) 1987-03-09
AU2809277A (en) 1979-03-01
NL7709246A (nl) 1978-02-27
AR222453A1 (es) 1981-05-29
IE45470B1 (en) 1982-09-08
JPS5340755A (en) 1978-04-13
IT1143757B (it) 1986-10-22
NO772917L (no) 1978-02-24

Similar Documents

Publication Publication Date Title
FI88504C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-benzyl-1-(2H)-ftalazinonderivat
JPS6089474A (ja) モルフイナン誘導体,その製造方法,及び該化合物を含有する抗腫瘍剤
CS240998B2 (en) Production method of 1,4-dihydropiridines
FI66859C (fi) Foerfarande foer framstaellning av 4-aminotiofen-3-karboxylsyraderivat med fysiologisk verkan
PT86716B (pt) Processo para a preparacao de derivados de pitidina
EA004931B1 (ru) 3, 4, 5-тризамещенные арилнитроны и содержащие их фармацевтические композиции
CA2037812A1 (fr) Derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant
EP0816338B1 (de) 3-(bis-substituierte-phenylmethylen)oxindol-derivate
PT91555B (pt) Processo de preparacao de derivados de dibenzo{2,3:6,7}-(oxepino ou tiepino){4,5-c}(piridina ou pirrol)e de composicoes farmaceuticas que os contem
BRPI0211025B1 (pt) um novo composto para o tratamento da impotência
CA2204007A1 (en) Remedy for diseases caused by infection with helicobacter
FI60863B (fi) Foerfarande foer framstaellning av nya bentshydryloxialkylaminderivat med foerlaengd antihistamineffekt
WO1998023606A1 (fr) Derives dithio cycliques, remedes contre des maladies renales diabetiques, agents hypoglycemiques, agents hypolipidemiques et agents lenitifs contre les troubles digestifs
US3558645A (en) 2-(4-(4',5-diphenyl - 2 - imidazolyl)-phenoxy) lower aliphatic monocarboxylic acids
US4446151A (en) Decarboxylase-inhibiting fluorinated pentane diamine derivatives
WO2021246408A1 (ja) 化合物又はその塩、医薬、抗利尿薬及びプロテインキナ-ゼa活性化薬
FR2465733A1 (fr) Nouveaux derives imidazolylethoxymethyliques de 1,3-dioxoloquinoleines utiles notamment comme medicaments antibacteriens et antifongiques, leur procede de preparation et compositions therapeutiques et formes pharmaceutiques les contenant
FR2973376A1 (fr) Derives utiles dans le traitement ou la prevention de tumeurs osseuses
US3635971A (en) 3 (3 4-dihydro-3-oxo-2-quinoxalinyl) propionamides
FI80440B (fi) Analogifoerfarande foer framstaellning av terapeutiskt anvaendbara afidkolanderivat.
TW580495B (en) An 1,4-dihydropiridine derivative chemically with guaiacoxypropanolamine based phenoxypropanolamine moiety
FI68622C (fi) Foerfarande foer framstaellning av indolaettiksyraderivat
US3558626A (en) 2-(4 - (diphenyl-2-pyrimidinyl)phenoxy) lower aliphatic monocarbocyclic acids and esters
US3577419A (en) 2,6-disubstituted-4-(omega-aminoalkoxy) phenyl pyrimidines
FI69065B (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla 3-(1-karboxi-alkoxi)-pyrazolderivat

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE AG