CH627166A5 - - Google Patents

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Publication number
CH627166A5
CH627166A5 CH742480A CH742480A CH627166A5 CH 627166 A5 CH627166 A5 CH 627166A5 CH 742480 A CH742480 A CH 742480A CH 742480 A CH742480 A CH 742480A CH 627166 A5 CH627166 A5 CH 627166A5
Authority
CH
Switzerland
Prior art keywords
piperidine
formula
phenoxymethyl
compounds
mol
Prior art date
Application number
CH742480A
Other languages
German (de)
English (en)
Inventor
Walter-Gunar Dr Rer Nat Friebe
Max Dr Rer Nat Thiel
Kurt Dr Stach
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of CH627166A5 publication Critical patent/CH627166A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
CH742480A 1975-11-07 1980-10-03 CH627166A5 (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752549999 DE2549999A1 (de) 1975-11-07 1975-11-07 Piperidin-derivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
CH627166A5 true CH627166A5 (nl) 1981-12-31

Family

ID=5961166

Family Applications (3)

Application Number Title Priority Date Filing Date
CH1385576A CH624102A5 (nl) 1975-11-07 1976-11-03
CH742480A CH627166A5 (nl) 1975-11-07 1980-10-03
CH742380A CH625788A5 (nl) 1975-11-07 1980-10-03

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1385576A CH624102A5 (nl) 1975-11-07 1976-11-03

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH742380A CH625788A5 (nl) 1975-11-07 1980-10-03

Country Status (20)

Country Link
US (1) US4243807A (nl)
JP (1) JPS6055509B2 (nl)
AT (1) AT352726B (nl)
BE (1) BE847973A (nl)
CA (1) CA1077942A (nl)
CH (3) CH624102A5 (nl)
DD (1) DD126942A5 (nl)
DE (1) DE2549999A1 (nl)
DK (1) DK494876A (nl)
FI (1) FI763148A (nl)
FR (1) FR2330678A1 (nl)
GB (1) GB1502050A (nl)
HU (1) HU171237B (nl)
IE (1) IE43866B1 (nl)
IT (1) IT1063618B (nl)
LU (1) LU76141A1 (nl)
NL (1) NL7612286A (nl)
SE (1) SE7612234L (nl)
SU (3) SU633473A3 (nl)
ZA (1) ZA766381B (nl)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA848275B (en) * 1983-12-28 1985-08-28 Degussa New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring
US4556664A (en) * 1984-03-13 1985-12-03 Gunnar A. K. Aberg Method and composition for the treatment of cardiac arrhythmias
IE66332B1 (en) * 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use
US5231184A (en) * 1987-11-23 1993-07-27 Janssen Pharmaceutica N.V. Pridazinamine derivatives
US4822778A (en) * 1988-01-19 1989-04-18 Gunnar Aberg Membrane stabilizing phenoxy-piperidine compounds and pharmaceutical compositions employing such compounds
US5109002A (en) * 1989-09-08 1992-04-28 Du Pont Merck Pharmaceutical Company Antipsychotic 1-cycloalkylpiperidines
NZ239846A (en) * 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
US5264420A (en) * 1990-09-27 1993-11-23 Merck & Co., Inc. Fibrinogen receptor antagonists
IL99537A (en) * 1990-09-27 1995-11-27 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical preparations containing them
FR2667317B1 (fr) * 1990-10-02 1992-12-04 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
HUT68769A (en) * 1991-05-07 1995-07-28 Merck & Co Inc FIBRINOGéN RECEPTOR ANTAGONIST COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AS EFFECTIVE SUBSTANCE
US5321034A (en) * 1991-05-07 1994-06-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5389631A (en) * 1991-10-29 1995-02-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5272158A (en) * 1991-10-29 1993-12-21 Merck & Co., Inc. Fibrinogen receptor antagonists
US5416099A (en) * 1991-10-29 1995-05-16 Merck & Co., Inc. Fibrinogen receptor antagonists
US5559127A (en) * 1992-10-14 1996-09-24 Merck & Co., Inc. Fibrinogen receptor antagonists
US5358956A (en) * 1992-10-14 1994-10-25 Merck & Co., Inc. Fibrinogen receptor antagonists
EP0673247A4 (en) * 1992-12-01 1996-05-01 Merck & Co Inc FIBRINOGEN RECEPTOR ANTAGONISTS.
US5441952A (en) * 1993-04-05 1995-08-15 Merck & Co., Inc. Fibrinogen receptor antagonists
US5334596A (en) * 1993-05-11 1994-08-02 Merck & Co., Inc. Fibrinogen receptor antagonists
US5397791A (en) * 1993-08-09 1995-03-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5821241A (en) * 1994-02-22 1998-10-13 Merck & Co., Inc. Fibrinogen receptor antagonists
US5719144A (en) * 1995-02-22 1998-02-17 Merck & Co., Inc. Fibrinogen receptor antagonists
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
WO1997011939A1 (fr) * 1995-09-28 1997-04-03 Kaken Pharmaceutical Co., Ltd. Procede d'elaboration de 4-methylenepiperidines
US5789421A (en) * 1995-10-26 1998-08-04 Merck & Co., Inc. Fibrinogen receptor antagonist
US5780480A (en) * 1996-02-28 1998-07-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5889023A (en) * 1996-05-10 1999-03-30 Merck & Co., Inc. Fibrinogen receptor antagonist
US5981584A (en) * 1997-02-06 1999-11-09 Merck & Co., Inc. Fibrinogen receptor antagonist prodrugs
US7888386B2 (en) * 2008-07-24 2011-02-15 Theravance, Inc. 3-(phenoxyphenylmethyl)pyrrolidine compounds
DK2358674T3 (da) 2008-11-14 2013-04-08 Theravance Inc Fremgangsmåde til fremstilling af 4-[2-(2-fluorphenoxymethyl)phenyl]piperidinforbindelser
WO2010120910A1 (en) * 2009-04-15 2010-10-21 Theravance, Inc. 3-(phenoxypyrrolidin-3-yl-methyl)heteroaryl, 3-(phenylpyrrolidin-3-ylmethoxy)heteroaryl, and 3-(heteroarylpyrrolidin-3-ylmethoxy)heteroaryl compounds
MX2012000685A (es) * 2009-07-13 2012-02-28 Theravance Inc Compuesto de 3-fenoximetilpirrolidina.
ES2495366T3 (es) 2009-07-21 2014-09-17 Theravance, Inc. Compuestos de 3-fenoximetilpirrolidina
EP2523945A1 (en) * 2010-01-11 2012-11-21 Theravance, Inc. 1 - (2 - phenoxymethylphenyl) piperazine compounds as serotonin and norepinephrine reuptake inhibitors
ES2543064T3 (es) * 2010-03-22 2015-08-14 Theravance Biopharma R&D Ip, Llc Compuestos de 1-(2-fenoximetilheteroaril)piperidina y piperazina
WO2012051103A1 (en) 2010-10-11 2012-04-19 Theravance, Inc. Serotonin reuptake inhibitors
WO2012075239A1 (en) 2010-12-03 2012-06-07 Theravance, Inc. Serotonin reuptake inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268951A (en) * 1969-06-12 1972-03-29 Pfizer Ltd Phenoxy-amines
DE2245061A1 (de) * 1972-09-14 1974-03-28 Boehringer Mannheim Gmbh Derivate des adenins
DE2401254A1 (de) * 1974-01-11 1975-11-27 Boehringer Mannheim Gmbh Neue derivate von n hoch 6-substituierten adeninen
DE2550000A1 (de) * 1975-11-07 1977-05-12 Boehringer Mannheim Gmbh Neue purin-derivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DE2549999A1 (de) 1977-05-12
DE2549999C2 (nl) 1989-01-26
AT352726B (de) 1979-10-10
ZA766381B (en) 1977-10-26
SU662009A3 (ru) 1979-05-05
HU171237B (hu) 1977-12-28
SU633473A3 (ru) 1978-11-15
ATA823776A (de) 1979-03-15
DK494876A (da) 1977-05-08
DD126942A5 (nl) 1977-08-24
IE43866L (en) 1977-05-07
CH624102A5 (nl) 1981-07-15
CA1077942A (en) 1980-05-20
SU867298A3 (ru) 1981-09-23
FI763148A (nl) 1977-05-08
NL7612286A (nl) 1977-05-10
LU76141A1 (nl) 1977-05-18
SE7612234L (sv) 1977-05-07
CH625788A5 (nl) 1981-10-15
BE847973A (fr) 1977-05-04
JPS5259163A (en) 1977-05-16
FR2330678B1 (nl) 1980-11-07
JPS6055509B2 (ja) 1985-12-05
IT1063618B (it) 1985-02-11
FR2330678A1 (fr) 1977-06-03
GB1502050A (en) 1978-02-22
IE43866B1 (en) 1981-06-17
US4243807A (en) 1981-01-06

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PL Patent ceased